8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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EL^MDEF DB@@IHI BL GIE@QG (EDG)

N.SGE^J ]IE^ > TIJITQI^ 4 XIIO 5 FBQIT;

JBFAE]; Qbxmb!b"# ($".>)

Q%ITAE]; S&'b!b"# ($".)

XIAFITAE]; J*+m&! T'&'m,'m, ($".5-)

QG%^TAE]; Qbxmb!b"# ($".5)

L^MAE]; S&'b!b"# ($".>/)

3%ITQMBFT I&m!; &1m&9b!!*"*b'

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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QB7MDB@BH] (JBFAE])

MFQ^BA%DQMBF;

Qgi Xbr`a Gie`tg Brhefmzetmbfs (XGB) ailmfmtmbf bl

aruh aipifaifdi ms e steti, psydgmd efa sbjitmjispgysmde`, risu`tmfh lrbj tgi mftiredtmbf nitwiif e

`mmfh brhefmsj efa e aruh dgeredtirmzia ny nigembre`

efa btgir rispbfsis tget e`weys mfd`uai e dbjpu`smbf tb

te!i tgi aruh bf e dbftmfubus br pirmbamd nesms mf

brair tb i"pirmifdi mts psydgmd illidts efa sbjitmjis

tb ebma tgi amsdbjlbrt bl mts ensifdi#

$bri ridift ailmfmtmbfs mfd`uai tgi XGBs %&'* efa

tgi +jirmdef sydgmetrmd +ssbdmetmbfs '-$%.

amehfbstmd drmtirme lbr -unstefdi/i`etia 'msbrairs,

wgmdg ijpgesmzi tgi mjpbrtefdi bl `bss bl dbftrb` bir

aruh usi efa mts dbfsi3uifdis mf `mjmtmfh btgir, fbf

aruhri`etia edtmmtmis, mf eaamtmbf tb tb`irefdi efa

pgysmde` aipifaifdi# %f tgi enbi ailmfmtmbfs, e

amstmfdtmbf ms jeai nitwiif pgysmde` efa psydgb`bhmde`

aipifaifdi# +`tgbuhg psydgb`bhmde` aipifaifdi ges fbt

niif sgbwf tb prbaudi hrbss strudture` dgefhis, mt justni essujia tget dgefhis gei bddurria mf tgi nremf et e

jb`idu`er br ridiptbr `ii`#

&iftre` tb tgi ailmfmtmbf bl psydgb`bhmde` aipifaifdi

ms tgi dbjpu`smbf br dremfh tb te!i e aruh ripietia`y#

%f dbftrest, pgysmde` aipifaifdi bddurs mf tgi ensifdi

bl e aruh, wgif e refhi bl syjptbjs 5 e wmtgarewe`

steti 5 ms prisift# Qgi iesi efa aihrii tb wgmdg

wmtgarewe` syjptbjs aii`bp ailmfis tgi `menm`mty bl epertmdu`er aruh tb prbaudi pgysmde` aipifaifdi# +s e

hifire`mzetmbf, tgi wmtgarewe` syfarbji siif eltir

dissetmbf bl e aruh tifas tb ni tgi bppbsmti bl tgi

syjptbjs prbaudia ny eduti eajmfmstretmbf bl tget aruh

(i#h# ef"mity, mfsbjfme efa erbuse` siif eltir

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wmtgarewe` bl e`dbgb` br nifzbamezipmfis, br aiprissmbf

efa `itgerhy siif eltir wmtgarewe` bl stmju`efts)#

gysmde` efa psydgb`bhmde` aipifaifdi jey ni

amstmfhumsgia d`mfmde``y# >br mfstefdi, enrupt

dissetmbf bl trmdyd`md eftmaiprissefts `ieas tb

syjpetgitmd firbus systij edtmetmbf, wmtgbut

psydgb`bhmde` aipifaifdi, wgiries fmdbtmfi wmtgarewe`

prbaudis priabjmfeft`y psydgb`bhmde` dgefhis, wmtg

jmfmje` pgysmde` syjptbjs# Qgi je4br amllirifdi nitwiif

aruh enusi efa aruh aipifaifdi ms 3ueftmtetmi#

Qb`irefdi, wgif ripietia i"pbsuri tb e aruh prbaudis

prbhrissmi`y amjmfmsgia illidts, ms efbtgir mjpbrteftdbfdipt# %t jey ni deusia ny dgefhis mf tgi reti et

wgmdg tgi aruh ms amstrmnutia br jitenb`mzia mf tgi

nbay, br ny eaeptmi prbdissis bddurrmfh mf tgi nremf#

+ amstmfdt lieturi ms drbss tb`irefdi, wgiri tb`irefdi

tb bfi typi bl aruh ms essbdmetia wmtg tb`irefdi tb

btgir aruhs# &rbsstb`irefdi, wgmdg def ifdbjpess

dgijmde``y amstmfdt aruhs, ges niif d`ier`y

aijbfstretia lbr e`dbgb`, nifzbamezipmfis efa btgir

siaetmi aruhs# %t lbrjs tgi nesms lbr sunstmtutmbf

trietjift bl aipifaifdy#

L*&'=1*, b +1=" +*$*9+*9*;

1 + sun4idtmi ewerifiss br dbjpu`smbf tb usi e aruh,

bltif ri`etia tb ufsuddisslu` illbrts tb riaudi aruh

mfte!i#

1 &bftmfuia aruh usi aispmti ewerifiss bl mts gerjlu`

illidts bf pgysmde` gie`tg, sbdme` lufdtmbfmfh, itd#

1 rmbrmty bl aruhte!mfh br bntemfmfh aruhs bir btgir

edtmmtmis, `mjmtmfh fbrje` sbdme` br wbr! rb`is#

1 Qgi aii`bpjift bl tb`irefdi efa wmtgarewe` syjptbjs#

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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1 +ltir enstmfifdi, aipifaifdi jey ridur repma`y wmtg

riusi bl tgi aruh#

SEQGBSG]TMB@BH] BL A^%H AISIFAIFDI;

$bst pibp`i wgb eri i"pbsia tb aruhs ab fbt nidbjiaipifaift bf tgij# >edtbrs tget mfdriesi tgi `m!i`mgbba

bl eaamdtmbf mfd`uai9

1

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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SEQGB@BH] (Q%ITAE])

Q* *!! &9+ *!! m9=1#;

TQ^%DQ%^I EFA L%FDQMBF BL DI@@ DBJSBFIFQT?

;ud`ius Qgi fud`ius ms dbjpbsia prmfdmpe``y bl

aib"yrmnbfud`imd edma (';+) mf dbjnmfetmbf wmtg e

prbtimf (gmstbfi) wmtgmf e hrbufa sunstefdi# Qgi

fud`imd edma jetirme` (dgrbjetmf) stemfs wi`` wmtg

nesmd ayis sudg es geijetb"y`mf efa jitgy`ifi n`ui, efa

';+ def ni stemfia spidmlmde``y ny tgi >iu`hif

tidgfm3ui# &grbjetmf pettirfs ery lrbj di`` tb di``#

Qgi p`esje di``, lbr i"ejp`i, ges e amstmfdtmi

?dertwgii`? pettirf# Q* 9=!*=,ms siperetia lrbj tgidytbp`esj ny e abun`i jijnrefi tgi fud`ier ifi`bpi

dbftemfmfh dmrdu`er gb`is 0* tb :* fj mf amejitir

fud`ier pbris# Qgi pbris, wgmdg eri usue``y drbssia ny

e amllusi jijnrefi, prbnen`y riprisift tgi smtis bl

mftirdgefhi nitwiif fud`ius efa dytbp`esj#

L=9'mb9, b '* 9=!*=,;

# /ip`mdetmbf bl ';+

6# rbaudtmbf bl jissifhir /;+

2# -yftgisms bl sbji fud`ier prbtimfs ;ud`ib`us Qgi

fud`ius fbrje``y dbftemfs bfi br jbri sje`` nesbpgm`md

strudturis fud`ib`m, dbjpbsia bl e aifsi fitwbr!

(fud`ib`bfije) ifd`bsmfh pe`ir eries (tgi pers

ejbrpge)# Qgi hrefu`is bl tgi fud`ib`bfije eri tgbuhgt

tb riprisift fiw`ysyftgismzia rmnbsbji sunufmts wgmdg

pess but bl tgi fud`ius e`bfh wmtg jissifhir /;+ efa

amridt tgi syftgisms bl spidmlmd prbtimfs mf tgidytbp`esj# &ytbp`esj &ytbsb` amllirs lrbj i"tredi``u`er

l`uma mf gemfh e gmhg dbfdiftretmbf bl pbtessmuj,

jehfismuj efa pgbspgeti# -bamuj ms edtmi`y i"d`uaia ny

tgi +Qaipifaift ?sbamujpujp? edrbss tgi di``

jijnrefi# $efy lufdtmbfs rismai mf tgi dytbsb` br

dytbp`esjmd jetrm", feji`y9

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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# etty edma syftgisms

0# $bfbfud`ibtmai syftgisms

E# gbspgbh`udbfeti petgwey

:# -idbfa jissifhir smhfe`mfh petgweys $mtbdgbfarme

Qgisi rbufa, bbma, br smfubus dytbp`esjmd brhefi``ispbssiss e dbjp`iti butir trm`ejmfer jijnrefi efa ef

mffir jijnrefi wgmdg sgbws fujirbus mflb`amfhs tirjia

drmstei# +`tgbuhg e`` jmtbdgbfarme gei tgms nesmd

strudturi tgiri ms dbfsmairen`i ermenm`mty nbtg mf tgi

fujnir efa `ifhtg bl tgi drmstei efa mf tgi fujnir efa

hifire` but`mfi bl tgi jmtbdgbfarme#

&i``s wmtg e gmhg jitenb`md edtmmty gei `erhi

jmtbdgbfarme wmtg fujirbus drmstei, lbr i"ejp`i deramed

jusd`i efa hestrmd permite` di``s# %f tgi `mir, wgm`sttgi jmtbdgbfarme eri `erhi, tgi drmstei eri spersi efa

mrrihu`er# $mtbdgbfarme dbftemf jbst bl tgi ifzyjis bl

tgi dmtrmd edma dyd`i efa tgi ifirhy airmia lrbj tgi

b"maetmbf bl edity` &b+ mf tgi dyd`i ms usia tb

dbfirt eaifbsmfi ampgbspgeti tb trmpgbspgeti

b"maetmi pgbspgbry`etmbf#

I9+b$!&,m 1*'m=!=;+`` di``s dbftemf e systij bldbjp`i" pemria jijnrefis ifd`bsmfh sje`` ismd`is br

dgeffi`s tgi dmstirfei# Qgisi jijnrefis lbrj tgi

ifabp`esjmd ritmdu`uj (8/) efa eri imtgir stuaaia wmtg

rmnbsbjis lbrjmfh sbde``ia rbuhg 8/ br eri aibma bl

hrefu`is efa eri tirjia sjbbtg 8/# Qgi jemf lufdtmbf bl

tgi rbuhg 8/, tbhitgir wmtg lrii rmnbsbjis mf tgi

dytbp`esj, ms prbtimf syftgisms# rbtimf prbaudia ny

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tgi rbuhg 8/ ms usue``y lbr i"pbrt me tgi

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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2# Qrefspbrt petgweys lbr sidritmbfs efa btgir

brhefi``is

C# &m`mery edtmmty

0# gehbdytbsms

E# -ifsbry trefsaudtmbf, i#h# mf pb`yjbrpgs

:# &i`` jbtm`mty %ftirjiameti lm`ejifts %ftirjiameti

lm`ejifts eri tunu`er strudturis : fj mf amejitir

dbjpbsia bl pb`yjirs bl bfi br jbri (up tb *)

pb`ypiptmais# Qgi ermbus pb`yjirs sgbw e aihrii bl

tmssui spidmlmdmty efa tgimr aitidtmbf ges prbia

usilu` mf tgi dgeredtirmzetmbfs bl tujbur di``s# Qm,,=*,$*mmm'# m, &, b!!b:,9

# .mjiftmf jisifdgyje` di``s

6# 'isjmf jusd`i di``s

2# &ytb!iretmfs ipmtgi`me` di``s

C# ;iurblm`ejifts fiurbfis

0#

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wmtg prmjery `ysbsbjis# 'mhistmbf prbdiias mf tgi

sidbfaery `ysbsbjis sblbrjia efa prbaudts amllusi but

tb ni riutm`msia ny tgi di``# Dfamhistia jetirme` def

mf sbji mfstefdis ni i"pi``ia ny i"bdytbsms, btgirwmsi

mt rijemfs mf tgi di`` es e rismaue` aifsi nbay#

8"ejp`is bl prbtimfs te!if mftb di``s efa amhistia

wmtgmf `ysbsbjis eri9

# Geijbh`bnmf

6# ;etmi mjjufbh`bnu`mf efa mjjufi dbjp`i"is

2# 'ifeturia prbtimfs

C# rbtimf riensbrptmbf mf rife` tunu`is Nysbsbjis erimjpbrteft mf9

# b`yjbrpgs efa jedrbpgehis mf !m``mfh efa amhistmfh

mflidtmi ehifts

6# /ijbe` bl ufweftia di``s aurmfh ijnrybfmd

aii`bpjift

2# 'mspbse` bl i"diss sidritery prbaudts mf h`efau`er

di``s

C# Bstibdmestmd rijbai``mfh bl nbfi ny sidritia ifzyjis

0# -upp`y bl futrmifts, i#h# mf `mir $mdrbnbamis

$mdrbnbamis br pirb"msbjis dbfsmst bl e gbjbhifibus

jetrm" sbjitmjis dbftemfmfh e diftre` dryste``mfi

fud`ius ifd`bsia mf e smfh`i jijnrefi# Qgiy dbftemf e

fujnir bl ifzyjis, mfd`uamfh ejmfbedma b"maesis, ureti

b"maesi efa dete`esi, efa eri jbst fujirbus mf `mir

efa !mafiy di``s# Qgimr rb`i mf tgi di`` idbfbjy ms

bnsduri nut bfi bl tgimr lufdtmbfs jey ni tgi

rihu`etmbf bl n`bba `mpma `ii`s# &i`` jijnrefi &i``s

eri ifd`bsia ny e ufmt jijnrefi dbjpbsia bl `mpmas,

prbtimfs, efa b`mhb efa pb`yseddgermais# Qgi jijnrefi

ms issiftme``y e pgbspgb`mpma nm`eyir wmtg tgi

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gyarbpgbnmd `mpma jbmitmis mftirfe`msia efa tgi

prbtimfs (efa h`ydbprbtimfs) prisift es9

# %ftihre` jijnrefi prbtimfs h`bnu`er prbtimfs

mftirde`etia tb erymfh aiptgs wmtgmf tgi nm`eyir efa

mf sbji mfstefdis dbjp`iti`y speffmfh tgi jijnrefi#

%ftihretia h`ydbprbtimfs eri e`weys errefhia sb tget

tgimr dernbgyareti jbmitmis eri i"pbsia et tgi di``

surledi wgiri tgiy edt es spidmlmd ridiptbr jb`idu`is#

Xgm`st sbji mftihre` prbtimfs eri depen`i bl `etire`

jbijift wmtgmf tgi `mpma nm`eyir (tgus e`tirmfh tgi

jb`idu`er pettirf prisiftia et tgi surledi) btgirs

eppier tb ni ettedgia tb jmdrbtunu`is efa

jmdrblm`ejifts efa jiameti ?trefsjijnrefi dytbs!i`ite`

dbftrb`?

6# irmpgire` jijnrefi prbtimfs eri fbt issiftme` tb

strudture` mftihrmty efa eri nbufa tb mftihre` prbtimfs

br h`ydb`mpmas ny mbfmd nbfas# Qgi di`` jijnrefi ges e

fujnir bl mjpbrteft lufdtmbfs9

# %fte!i bl i"bhifbus jetirme` ny pgehbdytbsms,

pmfbdytbsms br jmdrbpmfbdytbsms

6# -i`idtmi pirjienm`mty

2# Qgi +Qessbdmetia sbamujpujp wgmdg edtmi`y sgmlts

sbamuj mbfs edrbss tgi jijnrefi but bl tgi dytbp`esj

C# &i``tbdi`` dbftedt efa eagismbf ny jiefs bl

4ufdtmbfe` dbjp`i"is tmhgt 4ufdtmbf, mftirjiameti

4ufdtmbf, efa aisjbsbji

0# &bftedt mfgmnmtmbf tgi jidgefmsj wgiriny lurtgir

prb`mliretmbf efa jbijift bl di``s ms mfgmnmtia ny

dbftedt wmtg `m!i di``s

E# +ftmhifmdmty (gmstbdbjpetmnm`mty)

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:# /idbhfmtmbf tgi depedmty tb ridbhfmsi lbrimhf

eftmhifs efa e`tiria br illiti gbst di``s, rismais et

tgi di jijnrefi efa ms jiametia ny di``nbufa

eftmnbamis br eftmnbay`m!i jb`idu`is A# /idiptbr smtis

lbr stmju`etbry gbrjbfis, dytb!mfis efa btgir dgijmde`

jiametbrs#

S^BQIB@]TMT EFA S^BQIMF LB@AMFH;Xgm`i mt ms si`l imaift tget repma efa illmdmift

prbtib`ysms ms diftre` tb tgi prbpir lufdtmbfmfh bl tgi

di``, mt ms bf`y ridift`y tget tgi jidgefmsjs

dbftrb``mfh prbtib`ysms gei nihuf tb ni ufairstbba#

>br mfstefdi, tgiri ms e iry d`bsi dbffidtmbf nitwiif

prbtib`ysms efa dbftrb` bl tgi di`` dyd`i# %faiia e

smfh`i prbtimf, dyd`mf =, wgmdg edduju`etis aurmfh tgi

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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dbrridt trefs`bdetmbf, essijn`y, amsessijn`y efa

trefspbrt bl pb`ypiptmais efa prbtimf b`mhbjirs# Qgi

prbtimfs lmrst deji tb fbtmdi wgif lbufa mf i"dissmi

ejbufts es pert bl tgi di``u`er rispbfsi tb gmhg

tijpireturi, gifdi tgi feji ?gietsgbd!? prbtimfs# ;bw

tget mt ms eppridmetia tget tgiy eri issiftme` tb

fbrje` lufdtmbf efa mfdriesia mf jefy lbrjs bl mf4ury

tgiy eri tirjia striss prbtimfs efa dgepirbfi#

DI@@ 6 DI@@ EAGITMBF;

# Iufdtmbfe` jidgefmsjs

(m) 'isjbsbjis mftirdi``u`er 4ufdtmbfs `mf!ia tb tgi

mftirjiameti lm`ejifts bl tgi dytbs!i`itbf# Qgiy eri

dbjpbsia bl e sirmis bl trefsjijnrefi h`ydbprbtimfs efaprbtimfs tirjia aisjbh`imfs efa aisjbp`e!mfs

(mm) +agirifs 4ufdtmbfs wgmdg dbftemf amllirift lbrjs

bl trefsjijnrefi eagismbf jb`idu`is, tgi jemf jijnirs

nimfh tgi deagirmf lejm`y# Qgisi jb`idu`is eri

rispbfsmn`i lbr de`dmuj aipifaift mftirdi``u`er

eagismbf# Btgir 4ufdtmbfs nitwiif di``s, feji`y hep efa

tmhgt 4ufdtmbfs, eri fbt eagismi strudturis# Qgimr

lufdtmbf ms tb e``bw tgi pessehi bl sje`` jb`idu`is

mftb, br nitwiif, di``s#

6# ;bf4ufdtmbfe` jidgefmsjs %ftirdi``u`er eagismbf ms

e`sb ledm`mtetia ny jijnrefinbufa di`` eagismbf

jb`idu`is (&+$s)# -bji &+$s eri spidmlmd tb dirtemf

tmssuis wgiries btgirs, lbr i"ejp`i sbde``ia `mir

di`` eagismbf jb`idu`i (N&+$), eri wmai`y amstrmnutia

mf ipmtgi`me` efa btgir tmssuis# Qgi i"mstifdi bl fbf

spidmlmd eagismbf jb`idu`is jiefs tget bf`y e sje``

ripirtbmri bl sudg jb`idu`is ms ri3umria lbr eagismbf

nitwiif e ju`tmp`mdmty bl di`` typis#

DI@@ 6 JEQ^M7 EAGITMBF;

# Iufdtmbfe` jidgefmsjs

(m) Gijmaisjbsbjis nmfa di``s tb tgimr sunstretuj

(mm) >bde` dbftedts

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JIAMDE@ TQEQMTQMDT (XIAFITAE])

M9'1b+='mb9;

-tetmstmds ms tgi sdmifdi bl db``idtmfh, sujjermzmfh,

prisiftmfh efa mftirpritmfh aete, efa bl usmfh tgij tbistmjeti tgi jehfmtuai bl essbdmetmbfs efa tist

gypbtgisis# %t ges e diftre` rb`i mf jiamde`

mfistmhetmbfs# ;bt bf`y abis mt prbmai e wey bl

brhefmzmfh mflbrjetmbf bf e wmair efa jbri lbrje` nesms

tgef ri`ymfh bf tgi i"dgefhi bl efidabtis efa pirsbfe`

i"pirmifdi, mt te!is mftb eddbuft tgi mftrmfsmd

ermetmbf mfgirift mf jbst nmb`bhmde` prbdissis#

>br i"ejp`i, fbt bf`y abis n`bba prissuri amllir lrbj

pirsbf tb pirsbf, nut mf tgi seji pirsbf mt e`sb ermis

lrbj aey tb aey efa lrbj gbur tb gbur# %t ms tgi

mftirpritetmbf bl aete mf tgi prisifdi bl sudg

ermenm`mty tget `mis et tgi giert bl stetmstmds#

-tetmstmds ms usia tb ie`ueti tgi essbdmetmbf nitwiif

ef i"pbsuri ermen`i efa tgi butdbji bl mftirist# $bri

spidmlmde``y, mt ms usia tb jiesuri tgms essbdmetmbf mf

tgi aete db``idtia lrbj tgi pertmdu`er sejp`i bl

mfammaue`s mf bur stuay efa tb je!i mflirifdis enbut

mts `m!i`y smzi efa strifhtg mf tgi pbpu`etmbf lrbj

wgmdg tgi sejp`i wes airmia#

LMFAMFH QGI ^MHGQ TQEQMTQMDE@ JIQGBA;

Qgi epprbprmeti stetmstmde` jitgbas tb usi aipifa bf

tgi feturi bl tgi butdbji ermen`i bl mftirist# tgiy

jey ni issiftme``y bfi bl tgrii typis9

# ;ujirmde` butdbjis, sudg es nmrtg wimhgt br

dgb`istirb` `ii`#

6# =mfery butdbjis, sujjermzia es prbpbrtmbfs, rms!s br

baas, sudg es tgi prb pbrtmbf bl dgm`arif amehfbsia

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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wmtg estgje, tgi prbpbrtmbf bl petmifts mf iedg

trietjift hrbup wgb eri fb `bfhir gypirtifsmi, br tgi

rms! bl aymfh mf tgi lmrst yier bl `mli#

2# /etis bl jbrte`mty, jbrnmamty br surme` jiesuria

`bfhmtuamfe``y bir tmji, sudg es tgi surme` retis

lb``bwmfh amllirift trietjifts lbr nriest defdir, br

tgi fujnir bl ipmsbais bl amerrgbie pir pirsbf pir yier

ejbfh +%'- petmifts#

%FAI^TQEFAMFH QGI @MFOT NIQXIIF TQ%A] AITMHF2 EFE@]TMT

EFA MFQI^S^IQEQMBF;

Qgi risu`ts bl e stuay eri bf`y es hbba es tgi aete bf

wgmdg tgiy eri nesia# %t sterts ny i"p`emfmfh gbw tb

dgbbsi tgi rmhgt efe`ysms lbr iedg bl tgi jemf typis bl

stuay aismhf# %t tgif aisdrmnis gbw tb dgbbsi ef

epprbprmeti sejp`i smzi, tgi illidts bl jiesurijift

irrbr efa jmsd`essmlmdetmbf, efa tgi amllirift weys mf

wgmdg essbdmetmbfs def ni jiesuria efa mftirpritia#

>mfe``y, mt ms issiftme` tb p`ef efa dbfaudt

stetmstmde` efe`ysis mf e wey tget je"mjmzis tgi

3ue`mty efa mftirpritenm`mty bl tgi lmfamfhs# %f e

typmde` stuay, aete eri db``idtia bf e `erhi fujnir bl

ermen`is, efa mt def ni amllmdu`t tb aidmai wgmdg

jitgbas tb usi efa mf wget brair#

Q^]MFH B%Q;

+`jbst e`` stetmstmde` efe`ysis eri fbw abfi usmfh

dbjputirs, efa e`` nut iry `erhi aetesits (tgbsi wmtg

jiesurijifts jeai bf gufarias bl tgbusefas blmfammaue`s) def fbw ni efe`yzia usmfh stefaera

(ais!tbp br `eptbp) bllmdi br gbji dbjputirs# +`tgbuhg

smjp`i efe`ysis def ni abfi wmtg e gefagi`a

de`du`etbr, iif lbr tgisi tgi usi bl e dbjputir ms

ridbjjifaia nideusi risu`ts wm`` ni prbaudia jbri

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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3umd!`y efa ni jbri eddureti# >br jbri dbjp`i" efe`ysis

mt ms issiftme` tb usi dbjputirs# &bjputirs e`sb e``bw

prbaudtmbf bl gmhg 3ue`mty hrepgmde` amsp`eys#

Gbwiir, de`du`etbrs eri usilu` lbr 3umd! de`du`etmbfs

efa dgid!mfh bl risu`ts (nbtg bfis bwf efa tgbsi mf

sdmiftmlmd pepirs)# Qgi jmfmjuj ri3umrijifts eri !iys

lbr sdmiftmlmd lufdtmbfs (sudg es s3ueri rbbt efa

`bhermtgj) efa et `iest bfi jijbry# Qgi fiw hifiretmbf

bl gefagi`a dbjputirs efa pirsbfe` brhefmzirs ms

n`urrmfh tgi amstmfdtmbf nitwiif de`du`etbrs efa

dbjputirs, efa mt ms `m!i`y tget stetmstmde` sbltweri

lbr sudg aimdis wm`` nidbji eem`en`i mf tgi luturi#

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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QB7MDB@BH] (QG%^TAE])

HIFI^E@ S^MFDMS@IT BL Q^IEQMFH EAAMDQMBFT;

=y tgi tmji ef eaamdt prisifts lbr essissjift efa

trietjift, gi br sgi ms `m!i`y tb gei amirsi efaje4br prbn`ijs# Qgiri jey ni pgysmde` br jifte`

m``fiss, efa ijbtmbfe` br ettmtuamfe` prbn`ijs, wgmdg

jey gei dbftrmnutia tb tgi eaamdtmbf efa7br risu`tia

lrbj mt# Qgimr lmfefdme` efa `mmfh dmrdujstefdis jey

gei niif eairsi`y ellidtia ny tgimr aruh genmt efa

tgiy jey gei `ihe` prbn`ijs ri`etmfh tb aruh

pbssissmbf, mftb"mdetmbf (i#h# armf!5armmfh bllifdis),

br drmjmfe` edtmmtmis derrmia but tb lmfefdi aruhpurdgesis#

+ttmtuais tb aruh usi jey ni ufrie`mstmd (i#h# aifme`)#

Qgi nist dgefdi bl e suddisslu` butdbji ri3umris tget

e`` bl tgisi ledtbrs eri dbfsmairia, efa tgi usi bl e

wmai refhi bl trietjift bptmbfs ms `m!i`y tb ni jbri

suddisslu` tgef e ferrbw ripirtbmri# Qrietjift

bn4idtmis ery aipifamfh bf tgi aruh# &bjp`iti

enstmfifdi ms ijpgesmzia lbr fmdbtmfi, e`dbgb` brdbdemfi eaamdtmbf, wgiries lbr girbmf eaamdtmbf jefy

petmifts nifilmt lrbj jitgeabfi jemftifefdi# Btgir

bn4idtmis eri tb mjprbi tgi gie`tg efa sbdme`

lufdtmbfmfh bl eaamdtia petmifts#

Qrietjift suddiss def bf`y ni aitirjmfia bir e `bfh

tmji, nesia bf riaudtmbf mf aruh usi efa mjprbijifts

mf gie`tg efa sbdme` lufdtmbfmfh# + trietjift prbhrejji

sgbu`a mfd`uai jiamde` efa psydgmetrmd essissjift efapsydgb`bhmde` efa sbdme` suppbrt# +aamdts sgbu`a ni

rilirria tb spidme`mst sirmdis ml tgisi eri eem`en`i#

Btgir sirmdis nesia mf tgi b`uftery sidtbr (i#h#

+`dbgb`mds +fbfyjbus) eri e`sb e`uen`i efa

dbjp`ijiftery risburdis# $iamde` efa psydgmetrmd

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

18/32

essissjift jey fiia tb ni ripietia bfdi tgi petmift ms

enstmfift, es mt ms bltif amllmdu`t tb amehfbsi

eddureti`y dirtemf amsbrairs mf tgi prisifdi bl

wmtgarewe` syjptbjs (i#h# ef"mity, aiprissmbf efa

gypirtifsmbf eri lieturis bl e`dbgb` wmtgarewe`, nuteri e`sb dbjjbf mf enstmfift e`dbgb`mds)#

Qgi pgerjedb`bhmde` trietjift bl eaamdtmbfs, wgmdg

mfd`uais trietjift bl mftb"mdetmbf, aitb"mlmdetmbf

(rijbe` bl tgi aruh lrbj tgi nbay, mfd`uamfh

jefehijift bl wmtgarewe` syjp tbjs) efa trietjift tb

priift ri`epsi, ms amsdussia ni`bw#

BSMBMACFE^DBQMD EFE@HITMDT;

'mejbrpgmfi (girbmf) ms prilirria ny jbst bpmbma

eaamdts# %t ms bltif eau`tiretia wmtg btgir wgmti

pbwairs, sudg es 3umfmfi (wgmdg ms nmttir, `m!i

bpmetis), dellimfi, `edtbsi efa iif dge`!s, sterdg efa

te`d# 'ui tb tgi ermen`i purmty, tgi absi bl n`ed!

jer!it girbmf ms e`weys ufdirtemf# Qgi aruh ms te!if

mftreifbus`y, sundutefibus`y, bre``y br ny mfge`etmbf

bl sjb!ia girbmf# %f eaamtmbf tb tgi m``ihe` supp`y blgirbmf lrbj +lhgefmstef efa i`siwgiri, bpmbmas eri

bntemfia lrbj pgerjedy tgilts efa tgi `ihe`

prisdrmptmbf bl aruhs lbr trietjift bl tgi eaamdtmbf#

JIAMDE@ DBJS@MDEQMBFT;

Qgi je4brmty bl tgisi ri`eti tb usi bl mflidtia

fiia`is, tgi illidts bl dbftejmfetmfh sunstefdis usia

tb dut supp`mis br tgi `mlisty`i bl bpmbma eaamdts#

Qgisi eri tgi prmfdmpe` riesbfs lbr tgi aii`bpjift bl

jitgeabfi d`mfmds efa fiia`ii"dgefhi prbhrejjis#

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

19/32

B$mbm+ +1=", '&' &1* bb9!# &0=,*+;

A1=", Db*9'

'mejbrpgmfi $emf`y bntemfia bf tgi n`ed! jer!it#

%t ms bl ermen`i purmty efa dut wmtg

3umfmfi, te`d, `edtbsi, itd# %t ms

usue``y jm"ia wmtg wetir,

gietia uftm` amssb`ia, efa sbjitmjis

stremfia tgrbuhg dbttbf# %t jey ni

usia mftreifbus`y (jemf`mfmfh),

sundutefibus`y

(s!mf pbppmfh) br mfge`ia

(sfbrtia7dgesmfh tgi arehbf, ny

gietmfh up bf lbm` efa mfge`mfh tgisjb!i) (t76E*5H*jmf)

$itgeabfi Qgms ms tgi jemfstey bl aruh eaamdtmbf

d`mfmds, efa ms usue``y hmif es ef

i`m"mr (`bfh t76bl 0500g)# %t ms

iry amllmdu`t tb usi i`m"mr lbr

mf4idtmbf

'mpmpefbfi(

dyd`mzmfi efa

'mdbfe`)

rimbus`y judg usia ny fbfd`mfmd

abdtbrs trietmfh eaamdts# %t ms iesm`y

drusgia up efa amssb`ia lbr

mftreifbus usi

Btgir bpbmas +`` bpmbmas, mfd`uamfh jm"ia

ehbfmsts7eftehbfmsts (i#h#

nuprifbrpgmfi) gei tgi pbtiftme` tb

deusi aipifaifdi

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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SEQGB@BH] (L^MAE])

QGI DI@@ D]D@I EFA DI@@ ^IS^BA%DQMBF;

+ltir ammsmbf (jmtbsms) tgi di`` iftirs tgi lmrst

ristmfh pgesi

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

21/32

ny tgi prbhify di``s aurmfh tgimr `mlitmji# Q* 9=0*1b ,= &$!m#m9" +mm,mb9, m, b+mm*+ 0#;

# Qgi spetme` amstrmnutmbf bl di``s wmtgmf e tmssui

6# -urledi ettedgjifts

2# &ytb!mfis efa tgimr ridiptbrs

D]QBOMFIT;&ytb!mfis eri e lejm`y bl h`ydbsy`etia br fbf

h`ydbsy`etia pb`ypiptmais efa prbtimfs sidritia ny

di``s mf rispbfsi tb e stmju`us wgmdg jbau`etis tgi

nigembur bl terhit di``s# Qgiy i"irt tgimr illidts mf

tgrii weys9

(m) Qgiy edt bf tgi di`` prbaudmfh tgij ef eutbdrmfiillidt

(mm) Qgiy edt bf di``s mf tgi mdmfmty bl tgi prbaudmfh

di`` e peredrmfi illidt

(mmm) Qgiy edt systijmde``y bf amsteft smtis ef

ifabdrmfi illidt#

D!&,,*, b #'b8m9*,?#

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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(m) 8pmairje` hrbwtg ledtbr lejm`y e# 8pmairje` hrbwtg

ledtbr n# Qrefslbrjmfh hrbwtg ledtbr (" d# +jpgmrihu`mf

Qgisi s eri prbaudia ny jefy di`` typis# Qgiy

mftiredt wmtg tgi irn= lejm`y bl ridiptbrs efa eri

mjpbrteft mf ipmtgi`me` di`` prb`mliretmbf efa

amlliriftmetmbf

(mm) `eti`it airmia hrbwtg ledtbr (') 'mjirs bl

twb sunufmts '+ efa '= prbaudia ny p`eti`its,

ifabtgi`me` di``s, edtmetia jedrbpgehis itd#,

mjpbrteft mf tmssui ripemr efa dgrbfmd mfl`ejjetbry

prbdissis

(mmm) Qrefslbrjmfh hrbwtg ledtbr * lejm`yL

e# Q2 (je4br edtmbfs hrbwtg rihu`etmbf,

dbffidtmi tmssui syftgisms )

n# =$6+, 6= efa 2 (nbfi jbrpgbhifisms)d# %fgmnmfs + efa = (rihu`etmbf bl pmtumtery hbfea

e"ms)

a# +dtmmf + efa += (eftehbfmsj bl mfgmnmfs edtmbfs) i#

$u``irmef mfgmnmtbry sunstefdi (aii`bpjift bl je`i

riprbaudtmi systij)

(m) >mnrbn`est hrbwtg ledtbr (>)L

e# +dmamd >

n# =esmd >

d# mft 6

a# >0i# gst

Qgisi s eri pbtift stmju`etbry ledtbrs lbr

fiurbidtbairje` di``s, ifabtgi`me` di``s, lmnrbn`ests

itd#, efa p`ey e je4br rb`i mf ijnrybhifisms

() %fsu`mf`m!i hrbwtg ledtbr

e# Qypi %

n# Qypi $iameti edtmbf bl gbrjbfis sudg es hrbwtg

gbrjbfi

(m) ;iri hrbwtg ledtbrs

e# ;iri hrbwtg ledtbr

n# ;iurb`iu!mf ;iurbtrbpmd ledtbrs lbr fiure` tmssuis

wgmdg p`ey e rb`i mf wbufa gie`mfh

>. Db!b9# ,'m=!&'m9" &'b1,?

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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/ihu`eti tgi prb`mliretmbf efa amlliriftmetmbf bl

geijetbpbmitmd di``s#

D]QBOMFI ^IDISQB^T;/idiptbrs dbfsmst bl

(m) ef i"tirfe` abjemf wgmdg ms tgi nmfamfh smti lbr

tgi `mhefa

(mm) e trefsjijnrefi rihmbf wgmdg spefs tgi di``

jijnrefi

(mmm) ef mftredi``u`er abjemf wgmdg ai`mirs tgi smhfe`

tb tgi dytbsb` /idiptbrs jey dbfsmst bl e smfh`i

pb`ypiptmai dgemf bf mts bwf, i#h# 8/, e smfh`i

pb`ypiptmai dgemf p`us e sidbfa gi`pir prbtimf, i#h#

%>;,M ridiptbr, br twb pb`ypiptmai dgemfs, i#h# %ridiptbr# /idiptbrs def ni bl gmhg br `bw ellmfmty,

i#h# %N6, br tgiy def gei e amllirift `ii` bl

rispbfsi tb amllirift `mhefas, i#h# % ridiptbr

nmfamfh % efa mfsu`mf#

^**$'b1 b+=!&'mb9 m, &m**+ 0# &!'*1m9";

(m) tgi reti bl syftgisms efa jijnrefi mfsirtmbf

(mm) ridiptbr mftirfe`msetmbf efa ridyd`mfh

(mmm) ridiptbr aihreaetmbf me `ysbsbjis

Tm"9&! '1&9,+='mb9;>b``bwmfh nmfamfh bl dytb!mfi wmtg mts epprbprmeti

ridiptbr tgiri lb``bws e desdeai bl iifts tget

iiftue``y (eltir siire` gburs) `iea tb stmju`etmbf bl

';+ syftgisms efa di`` ammsmbf br mfaudtmbf bl $/;+

efa prbtimf syftgisms# Qgi jidgefmsjs mfb`ia mf tgms

?smhfe` trefsaudtmbf? eri gmhg`y dbjp`i"# -bji

ridiptbrs bpireti tgrbuhg edtmetmbf bl tgimr mftirfe`

tyrbsmfi !mfesi abjemf, i#h# irn= lejm`y, '/,

%rL btgirs trefsaudi tgimr smhfe`s me dytbp`esjmd

tyrbsmfi br sirmfi7tgribfmfi !mfesis, i#h# srd, yis,

lhrL yit btgirs bpireti tgrbuhg pgbspgb`mpesi&

edtmmty, i#h# dr!#

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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Qgisi ifzyjis edt tgrbuhg e sirmis bl mftirjiamermis

efa prbtimf pgbspgbry`etmbf tb ?swmtdg bf? ';+ efa

prbtimf syftgisms#

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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(m) =mbdgijmde``y spidmlmd ifzyji pbmsbfs sudg es

dyefmai bf dytbdgrbji b"maesiL sbamuj l`ubrediteti

n`bd! bl tgi Krins dyd`i

(mm) Qmssui spidmlmd i#h# pereditejb` (editejmfbpgif)

prbaudmfh `mir fidrbsmsL e``b"ef hmmfh rmsi tb

fidrbsms mf =di``s bl tgi pefdrietmd ms`its

(mmm)

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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E#

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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mfimten`i# Dfair sbji dmrdujstefdis tgi fiw

ifmrbfjift jey ri3umri e gimhgtifia steti bl edtmmty

lbr gbjibstesms tb ni jemftemfia# %fdriesia lufdtmbfe`

edtmmty ms nrbuhgt enbut ny ef mfdriesi mf tgi fujnir

bl brhefi``is efa e dbfdbjmteft mfdriesi mf di`` smzi

di``u`er gypirtrbpgy#

+f mfdriesi mf di`` fujnir jey ni ri3umria tb dbpi wmtg

mfdriesia aijefas br tb dbjpifseti lbr e sgbrtifia `mli

spef gypirp`esme# $bri lri3uift`y, e di`` eaepts tb

ef eairsi ifmrbfjift ny lufdtmbfmfh et e `bwir `ii`

tgef fbrje`# Qgi amjmfutmbf mf lufdtmbfe` brhefi``is ms

pere``i`ia ny riaudia di`` smzi etrbpgy# >mfe``y

tmssuis i"pbsia tb ef eairsi ifmrbfjift bir e

sustemfia pirmba jey eaept ny e`tirmfh tgi amridtmbf bldi``u`er amlliriftmetmbf tb prbaudi di``s jbri depen`i

bl dbjnetmfh tgi ifmrbfjift# -udg e dgefhi ms tirjia

jitep`esme#

T%N@IQGE@ DI@@ MF%^];-un`itge` mf4ury jey risu`t mf `bfhtirj eaeptmi

dgefhis br mf aihifiretmi dgefhis wgmdg def ni

riirsia nut jmhgt e`sb gire`a tgi bfsit bl di`` aietg#

Q* +*"*9*1&'m* b9,*=*9*, b *!! m9=1# b$1m,*;

# %f4ury tb di`` jijnrefis efa jmtbdgbfarme

(m) Nbss bl jmdrbmmmm efa lbde` i"pefsmbfs bl tgi

p`esje jijnrefi

(mm) >brjetmbf bl edub`is ny mflb`amfh bl tgi p`esje

jijnrefi ifabdytmd edub`etmbf

(mmm) 'msruptmbf bl tgi /8/ efa `bss bl rmnbsbjis# Qgms

nrmfhs enbut tgi `bss bl dytbp`esjmd nesbpgm`me siif bf

`mhgt jmdrbsdbpy

(m) $mtbdgbfarme` swi``mfh efa `bss bl drmstei

6# &`buay swi``mfh (mftredi``u`er biaije) Qgms risu`ts

lrbj tgi edduju`etmbf bl wetiry l`uma mf tgi am`etia

seds br dmstirfei bl tgi ifabp`esjmd ritmdu`uj efa

jmtbdgbfarme#

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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(m) 8er`y stehis ufair tgi `mhgt jmdrbsdbpi, tgi

dytbp`esj ges e lmfi hrefu`ermty `m!i hrbufah`ess (mm)

Netir stehis prbhrissmi am`etetmbf bl tgi 8/ `ieas

tb tgi eppierefdi bl d`ier edub`is msmn`i ny `mhgt

jmdrbsdbpy gyarbpmd edub`etmbf

J*&9m,?(m) >e`` mf b"maetmi pgbspgbry`etmbf aui tb

e# Ned! bl b"yhif

n# 'ejehi tb jmtbdgbfarme br mts ifzyjetmd petgweys Qgi

amjmfmsgia lbrjetmbf bl +Q ellidts e`` tgi ifirhy

ri3umrmfh riedtmbfs mf tgi di`` nut mf pertmdu`er `ieas

tb lem`uri bl tgi sbamujpujp# -bamuj mbfs iftir tgi

di`` mf i"dgefhi lbr pbtessmuj efa es tgi lbrjir gei e

`erhir gyaretmbf sgi``, tgiri ms e fit mfl`u" bl wetir#(mm) %fdriesia mftredi``u`er bsjbtmd prissuri risu`tmfh

lrbj

e# +dduju`etmbf bl `edteti efa pyrueti

n# ;it detenb`msj bl jedrbjb`idu`is

2# >etty dgefhi Qgms ms tgi eppierefdi bl enufaeft

spgirmde` h`bnu`is bl let (trmh`ydirmai) wmtgmf tgi

dytbp`esj# %t def ni aijbfstretia usmfh lrbzif sidtmbfsefa stemfmfh wmtg `mpmasb`un`i ayis sudg es Bm` ria *

br -uaef n`ed!, efa ms jbst dbjjbf`y siif mf di``s bl

tgi `mir, !mafiy efa jybderamuj# >etty dgefhi just ni

amstmfhumsgia lrbj petgb`bhmde` eampbsmty wgiri let

di``s (`mpbdytis) mflm`treti ef brhef br tmssui#

Qgms ms e lieturi bl siiri bnismty# %f fbrje` di``s

let ms gi`a mf e amspirsia steti efa trefspbrtia but bl

tgi di`` es jmdi``is br `mpbprbtimf dbjp`i"is

(trmh`ydirmai wmtg pgbspgb`mpma efa7br prbtimf)#

Qrmh`ydirmais eri syftgismsia lrbj lrii letty edmas

(>>+-) iftirmfh tgi di`` lrbj tgi n`bba# >>+s e`sb

ufairhb b"maetmbf tb &*6 efa dbfirsmbf tb

pgbspgb`mpma#

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

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J*&9m,? L&''# &9"* 1*,=!', 1b9+# %jpemria jitenb`msj bl let

(m) /iaudia b"maetmbf bl >>+s wmtg mfdriesia dbfirsmbf

tb trmh`ydirmais

(mm) /iaudia syftgisms bl pgbspgb`mpma efa prbtimf#

Qgms risu`ts mf

e# /iaudia amspirse` bl let `ieamfh tb h`bnu`i

lbrjetmbf

n# 'mjmfmsgia ri`iesi bl let lrbj tgi di`` es

`mpbprbtimf

=# 8"dissmi iftry bl >>+s efa trmh`ydirmai mftb tgi

di`` &eusis

(m) 'menitis ji``mtus

(mm) &bfhistmi deramed lem`uri(mmm) -iiri efeijme

(m) $e`futrmtmbf efa westmfh amsiesi

() %sdgeijme, i#h# dbrbfery mfsullmdmifdy

(m) %flidtmbfs (siptmdeijme)

(mm) &grbfmd e`dbgb`msj (`mir)

(mmm) bmsbfs, i#h# dernbf titredg`brmai, pgbspgbrus

(`mir)

C# Nysbsbje` aejehi

+# Nysbsbje` rupturi ms tgbuhgt tb ni rispbfsmn`i lbrsbji lbrjs bl di`` mf4ury, i#h# mf4ury tb e`ib`er

jedrbpgehis eltir pgehbdytbsms bl sm`mde# %f tb"md

mf4ury, gbwiir, rupturi ms tgbuhgt tb ni e dbfsi3uifdi

bl eaefdia di``u`er aejehi retgir tgef ef mfmtmetmfh

ledtbr#

=# Nysbsbje` bir`beamfh# $efy jitenb`md prbdissis

aipifa upbf tgi gyarb`ysms bl mftirjiametis ny

`ysbsbje` ifzyjis# Xgif e pertmdu`er gyarb`esi msailmdmift br ensift, e`` sunstefdis iftirmfh `ysbsbjis

br ermsmfh wmtgmf tgij tget ri3umri tgms ifzyji lbr

tgimr lurtgir amhistmbf, edduju`eti efa prbhrissmi`y

if`erhi tgi `ysbsbji# -unstefdis edduju`etmfh mf tgms

wey mfd`uai9

(m) Nmpblusdmf (sii ni`bw)

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

30/32

(mm)

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

31/32

e# 8pmtgi`me` di``s bl tgi ipmamayjms

n# %ftirstmtme` di``s bl tgi tistms

d#

8/10/2019 ACH's B.PHARM YEAR 2 SEMESTER 3 WEEK 1 NOTES

32/32

we`isbfjaOhjem`#dbj