Achondroplasia. Karyotypes and Nondisjunction Karyotype Picture of a persons’ chromosomes Allows...
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Transcript of Achondroplasia. Karyotypes and Nondisjunction Karyotype Picture of a persons’ chromosomes Allows...
KaryotypePicture of a persons’ chromosomes
Allows doctors to detect some genetic disorders
Reveals extra or missing chromosomes
KaryotypesPicture taken during metaphase of mitosis
Chromosomes are condensed and consist of 2 sister chromatids
DNA is stained prior to taking the picture. Similar DNA sequences glow similarly
Arranged by decreasing size
Telomeres
The ends of a chromosome
They serve a protective function
Their degradation leads to aging and cancer
Nondisjunction
Occurs when Sister Chromatids fail to separate
Can happen in Meiosis I or Meiosis II
Wrong number of chromosomes in a gamete