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AB SCIEX 5500 Series of Instruments

Site Planning Guide

Document Number: D5034384 ARelease Date: August 2012

This document is provided to customers who have purchased AB Sciex equipment to use in the operation of such AB Sciex equipment. This document is copyright protected and any reproduction of this document or any part of this document is strictly prohibited, except as AB Sciex may authorize in writing.Software that may be described in this document is furnished under a license agreement. It is against the law to copy, modify, or distribute the software on any medium, except as specifically allowed in the license agreement. Furthermore, the license agreement may prohibit the software from being disassembled, reverse engineered, or decompiled for any purpose.Portions of this document may make reference to other manufacturers and/or their products, which may contain parts whose names are registered as trademarks and/or function as trademarks of their respective owners. Any such use is intended only to designate those manufacturers' products as supplied by AB Sciex for incorporation into its equipment and does not imply any right and/or license to use or permit others to use such manufacturers' and/or their product names as trademarks.AB Sciex makes no warranties or representations as to the fitness of this equipment for any particular purpose and assumes no responsibility or contingent liability, including indirect or consequential damages, for any use to which the purchaser may put the equipment described herein, or for any adverse circumstances arising therefrom.For research use only. Not for use in diagnostic procedures.

The trademarks mentioned herein are the property of AB Sciex Pte. Ltd. or their respective owners.AB SCIEX™ is being used under license.

AB SCIEX71 Four Valley Dr., Concord, Ontario, Canada. L4K 4V8.AB Sciex LP is ISO 9001 registered.© 2012 AB SCIEX.Printed in Canada.

Contents

Chapter 1 Customer and FSE Responsibilities. . . . . . . . . . . . . . . . . . . . . . . . . . . 5Customer Site Planner Responsibilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5FSE Responsibilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6

During Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6Operator Familiarization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6

Technical Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6

Chapter 2 Site Planning Checklist . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7Customer Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .7Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .7Comments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11Exceptions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12Signoff . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12

Appendix A Site Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .13Site Layout Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .13

Weights and Dimensions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .13Layout Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .14Installation Site Clearances . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .16

Electrical Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .16International Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .16North American Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .16Mains Supply Fluctuations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .18Protective Earth Conductor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .18UPS (Uninterruptible Power Supply) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .18System Electrical Specifications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .19

Gas Supply Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20Optional Generators . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21

Ventilation and Waste-Collection Requirements . . . . . . . . . . . . . . . . . . . . . . . . .21General Guidelines for the Laboratory Ventilation System . . . . . . . . . . . . . . .22

Network and Computer Equipment Requirements . . . . . . . . . . . . . . . . . . . . . . .23Customer Printer Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .23LAN Connection (Optional) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .23

Environmental Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24Standard Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24Optional Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24Sound Pressure Specifications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24Vibration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24

Customer Supplied Solutions and Equipment . . . . . . . . . . . . . . . . . . . . . . . . . . .25

Appendix B Health and Safety Precautions . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27

Appendix C Equipment Safety Categories . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .29

Site Planning GuideD5034384 A

AB SCIEX 5500 Series of Instruments 3 of 30

Contents

AB SCIEX 5500 Series of Instruments4 of 30

Site Planning Guide D5034384 A

1

Customer and FSE Responsibilities

This guide is for the site planner, the individual responsible for preparing the facility for the installation of the AB SCIEX QTRAP® 5500 system or AB SCIEX Triple Quad™ 5500 system.

Customer Site Planner ResponsibilitiesCaution: Potential Instrument Damage: Do not unpack the mass spectrometer crate or computer boxes. The FSE will unpack and move the mass spectrometer at the time of the installation.

• Verify that adequate space and the required shipping facilities are available. Refer to Site Layout Requirements on page 13.

• Provide all required electrical receptacles. Refer to Electrical Requirements on page 16.

• Provide all required regulators, shut off valves, and gases, as detailed in this guide. Refer to Gas Supply Requirements on page 20.

• Provide and install all required vents and ventilation devices. Refer to Ventilation and Waste-Collection Requirements on page 21.

• Provide a printer and (optional) active, tested LAN connection. Refer to Network and Computer Equipment Requirements on page 23.

• Verify that the requirements for the operating environment are met. Refer to Environmental Requirements on page 24.

• Provide the required solutions and laboratory equipment, including all equipment, fittings, and sample tubing required for the liquid chromatography (LC) equipment, unless purchased from AB SCIEX. Refer to Customer Supplied Solutions and Equipment on page 25.

• Complete the checklist in Site Planning Checklist on page 7 and return it to the FSE.

Note: If the site preparation tasks are not complete when the AB SCIEX Field Service Employee (FSE) arrives, the scheduled installation will be postponed.

Note: The FSE will follow up if the checklist is not received prior to the scheduled installation date.



Customer and FSE Responsibilities

FSE Responsibilities• Supply all fittings, plugs, and cables required to connect the mass spectrometer to

the electrical receptacles, and regulators, provided they are within the maximum distances described herein.

• Assemble and set up any AB SCIEX benches ordered with the mass spectrometer.• Test and qualify the system to the specifications in the Installation Guide.• Set up LC equipment sold and supported by AB SCIEX. Integrate other supported

LC equipment.• Set up optional gas generator equipment sold by AB SCIEX only.

During InstallationAfter an FSE unpacks the system (with assistance from people at your site), it takes several hours for the FSE to set up the system and check its operation. When the system reaches proper vacuum, the FSE will perform installation qualification tests.

Operator FamiliarizationDuring installation, the FSE provides a system and software overview, reviews data, and provides some basic operator familiarization. Training for auxiliary equipment supplied by other manufacturers is not provided by the FSE.

Technical SupportAB SCIEX and its representatives maintain a staff of fully-trained service and technical specialists located throughout the world. They can answer questions about the system or any technical issues that may arise. For more information, visit the web site at www.absciex.com.

Note: Online training is available at www.absciex.com/training.



2
Site Planning Checklist
Customer Information

RequirementsCaution: Potential Instrument Damage: Do not unpack or connect any components. The FSE will unpack, connect, and configure the system for the proper operating voltage.

OrganizationAddress

CityCountry ZIP/Postal CodeTelephone # Fax #Site planner contact nameE-mail address

Table 2-1 Site Planning Checklist

Requirements CompleteSite Layout RequirementsRefer to Site Layout Requirements on page 13.The measured building clearances can accommodate the equipment and crate dimensions. If the requirements cannot be met, contact the FSE.

..

Electrical RequirementsRefer to Electrical Requirements on page 16.One branch circuit (200 VAC to 240 VAC) is provided for the mass spectrometer. The mains supply outlet is less than 1.6 m (69 inches) from the mass spectrometer.The optional bench can be connected to the mass spectrometer branch circuit.

..

One branch circuit (200 VAC to 240 VAC) is provided for the roughing pump. The mains supply outlet for the roughing pump is less than 1.6 m (69 inches) from the roughing pump.

..

Record the following values. The measured mains voltage over 24 hrs was:.• High value +%:• Low value –%:




The mains voltage source does not fluctuate more than ±10% from the nominal voltage.

Note: Peripheral devices may have different mains supply fluctuation limits. Check the mains supply fluctuation limit with the vendor of each peripheral device that will be used with the mass spectrometer.

..

The mains supply includes a correctly installed protective earth conductor. ..

(Optional) A customer-supplied UPS is provided for the system. The UPS must deliver 230 VAC, 50/60 Hz, 4000 VA (min). Refer to UPS (Uninterruptible Power Supply) on page 18.

..

(Optional) A customer-supplied power conditioner is provided for the system. It must deliver 230 VAC, 50/60 Hz, 4000 VA (min). Refer to UPS (Uninterruptible Power Supply) on page 18.

..

A qualified electrician has determined the appropriate mains supply configuration based on the system electrical specifications found in Table A-4 on page 19.

..

Electrical Requirements (North America)Refer to Electrical Requirements on page 16.The branch circuits referred to above:• Have duplex receptacles, nominal 15A 208/240 VAC (voltage fluctuations

between 180 VAC and 264 VAC), 50/60 Hz.• Are terminated with CSA/NEMA 6-15R receptacles.

..

Electrical Requirements (Accessories)A minimum of two mains supply outlets is provided for computer equipment (computer, monitor, printer): • North America:120 VAC, 60 Hz• Europe:230 VAC, 50 Hz• Japan: 100 VAC, 50/60 Hz

..

For optional devices: electrical outlets are provided as necessary for the LC pump, autosampler, diode array detector, and gas generator depending on equipment requirements and installation location. Refer to the documentation that comes with the device.

..

Gas Supply RequirementsRefer to Gas Supply Requirements on page 20.Gas 1/Gas 2 supply is available:

• Zero grade air• Delivery pressure of 100 psi (max.) with flows up to 22 L/min

..

Table 2-1 Site Planning Checklist (Continued)

Requirements Complete




Curtain Gas™ supply and CAD gas supply are available:• UHP nitrogen (99.999%)*• Delivery pressure up to 60 psi (max.) with flows up to 10 L/min

* or approved AB SCIEX gas generator

..

Source exhaust gas supply is available:• Clean, dry, and oil-free air or nitrogen• Maximum delivery pressure of 55 psi (3.8 bar) with flows up to 8 L/min

..

If an optional wall-mounted gas generator or the optional mass spectrometer bench is used, a supply of compressed oil-free air is provided, with a delivery pressure of 120 psi (8.3 bar).

..

Liquid nitrogen generators, if used, are secured to meet local safety standards and regulations. Use only regulators and connectors that comply with local regulations.

..

Gas delivery lines are installed as required by local safety standards and regulations.

..

Ventilation and Waste Collection RequirementsRefer to Ventilation and Waste-Collection Requirements on page 21.Installation of plumbing and ventilation fixtures complies with local bylaws and biohazard regulations.

..

A negative flow vent is provided with a total flow rate capacity of 283 L/min (10 cfm).

..

A smooth fitting is provided for the roughing pump, with an outside diameter (o.d.) of 3.2 cm (1.25 inch). The vent is within 1.5 m (5 ft) of the exhaust port on the roughing pump, and at least 1 m (3 ft) above the floor.

..

A fitting is provided for the source exhaust drain bottle with an o.d. of 1.3 cm (0.5 inch). The vent is within 1.5 m (5 ft) of the source exhaust drain bottle.

..

Ventilation of the laboratory environment in which the mass spectrometer will be used complies with local regulations, and the air exchange rate is appropriate for the work performed.

..

The length and number of bends in the ducting system is minimized. ..

The ventilation system uses smooth stainless steel tubing, with 45 degree elbows to turn corners.

..

(Recommended) The blower for the source exhaust system is equipped with an indicator light.

..

The length of the duct entering the blower is a straight length of at least ten times the duct diameter.

..

The outlet end of the ventilation system is equipped with a backdraft damper and exhaust stack, and is away from open windows or inlet vents.

..

The quantity of makeup air supplied matches the quantity of air exhausted by the system.

..






Computer RequirementsRefer to Network and Computer Equipment Requirements on page 23.A network or IT specialist is available to connect the computer to the company LAN while the AB SCIEX FSE is present.

..

A network computer name and domain password are available. ..

An active, tested LAN connection is available. ..

A network printer or a dedicated printer and necessary print drivers are available. ..

Environmental RequirementsRefer to Environmental Requirements on page 24.An ambient temperature of 15°C to 30°C (59°F to 86°F). The ambient temperature cannot change more than 2°C (3.6°F) per hour.

Note: Peripheral devices may have different operating environment requirements. Check the operating environment requirements with the vendor of each peripheral device that will be used with the system.

..

The relative humidity level is 20% to 80%, non-condensing. ..

Air conditioning provides a minimum of 6500 Btu/hr (mass spectrometer and roughing pump only).

..

(Optional) A customer-supplied soft wall is installed behind the mass spectrometer to reduce noise.

..

Mass Spectrometer BenchA bench is provided for the mass spectrometer, either a moveable bench or a fixed bench with 1 m (3 ft, 4 inches) of clearance on three sides for service access.

..

A bench is provided for the data acquisition workstation, located within 4 m (13 ft) of the mass spectrometer. Make sure that there is 1 m of clearance from the front, back, and left sides.

..

Materials Required for Routine OperationRefer to Customer Supplied Solutions and Equipment on page 25.All required solutions are available. .

.All required LC equipment and supplies are available. .

.Tubing and fittings required to connect the supported LC equipment to the mass spectrometer are available.

..

Additional Site PlanningComplete site planning for peripheral devices and software, as required. .

.






Comments

TrainingComplete the online training. Go to www.absciex.com/training. .

.Obtain and review system documentation. Go to www.absciex.com. Navigate to Downloads > Mass Spectrometry User Guides.

..






Exceptions

SignoffComplete the checklist and return it to the FSE email specified below on or before the Return Date.

Site Planner contact name

Site Planning Review Completion Date

I acknowledge that all installation requirements, as specified in this document, have been met.

..

FSE name Return dateFSE e-mail



A
Site Requirements
Site Layout RequirementsReturn to checklist.

Weights and DimensionsCheck the weight and dimensions in Table A-1 and make sure that you can move the system to the installation site. Make sure that the installation site can accommodate the equipment dimensions, weight, and associated clearance.The mass spectrometer has been designed to support 77 kg (170 lbs). The mass spectrometer bench is designed to support the weight of the mass spectrometer plus its associated load, roughing pump, and an additional 77 kg (170 lbs).

Note: The site must not be designated BioSafety Level 3 (BSL-3) or BSL-4. AB SCIEX does not install, service, or repair AB SCIEX mass spectrometers in areas designated BSL-3 or BSL-4.

Table A-1 Weights and Dimensions

Equipment Height Width Length WeightCrate 84.5 cm; 33.3 in. 99.3 cm; 39 in. 112 cm; 44 in. 70 kg; 154 lbs.Mass spectrometer 59 cm; 24 in. 79 cm; 32 in. 79 cm; 32 in. 130 kg; 285 lbs.Roughing pump 22 cm; 9 in. 30 cm; 12 in. 42 cm; 17 in. 34 kg; 75 lbs.Bench 78 cm; 31 in. 100 cm 40 in. 84 cm; 34 in. 120 kg; 265 lbs.Accessories crate 129.5 cm; 51 in. 104 cm; 41 in. 132 cm; 52 in. 178 kg; 391 lbs.



Site Requirements

Layout RequirementsReturn to checklist.Figure A-1 to Figure A-4 show examples of typical configurations.

Figure A-1 Layout configuration (not to scale)




Site Requirements





Site Requirements

Installation Site ClearancesReturn to checklist.Make sure the installation site meets the required building clearances. Refer to Table A-2.

Electrical RequirementsReturn to checklist.

The total combined system (mass spectrometer and roughing pump) power consumption is 2200 VA (50 Hz or 60 Hz) at 230 VAC. You do not need an external line transformer for the mass spectrometer, optional mass spectrometer bench, or roughing pump.

International RequirementsReturn to checklist.

• For installations outside North America, use locally approved standard connections and cables. If the voltage changes more than 10% in 24 hours, use a power conditioner.

North American RequirementsReturn to checklist.

• Two separate15A branch circuits are required to supply the mass spectrometer, roughing pump, and mass spectrometer bench. These branch circuits must

• Have duplex receptacles: nominal 15A 208/240 VAC. Total of four outlets.• Be equipped with CSA/NEMA 6-15R straight blade receptacles as shown in

Figure A-5.

Table A-2 Site Clearances

Clearance MeasurementFront, back, and left sides Mass spectrometer clearance requirement is 1 m for service

access.

WARNING! Electrical Shock Hazard: Use only qualified personnel for the installation of all electrical supplies and fixtures, and make sure that all installations adhere to local bylaws.



Site Requirements

Figure A-5 CSA/NEMA 6-15 duplex receptacle and plug• The optional gas generator requires an additional separate branch circuit equipped

with a CSA/NEMA 6-15R straight blade receptacle (208/240 VAC).• Additional outlets (120 VAC) are required for the computer, monitor, printer, and LC

equipment.

Figure A-6 System mains supply configuration

Item Description1 One 15 A branch circuit is required for the mass spectrometer.The optional

mass spectrometer bench can be plugged into the mass spectrometer branch circuit.

2 One 15 A branch circuit is required for the roughing pump.

3 One branch circuit is required for the optional gas generator.

4 Additional 120 VAC outlets for computer, monitor, printer, and LC equipment as required.

12

3

4



Site Requirements

Mains Supply FluctuationsReturn to checklist.In areas where the mains supply is subject to voltage fluctuations exceeding ±10% of the nominal value (200 VAC to 240 VAC), a power conditioner may be required. High or low voltages can adversely affect the electronic components of the mass spectrometer. Refer to Table A-3.

Protective Earth ConductorReturn to checklist.The mains supply must include a correctly installed protective earth conductor that must be installed or checked by a qualified electrician before connecting the mass spectrometer.

UPS (Uninterruptible Power Supply)Return to checklist.Use a pure sine-wave UPS or power conditioner to maintain the system supply (mass spectrometer, computer, monitor, and roughing pump) during power outages.If you power the system from a UPS or power conditioner, it must meet the following specifications.

Note: Peripheral devices may have different mains supply fluctuation limits. Check the mains supply fluctuation limit with the manufacturer of each peripheral device that will be used with the mass spectrometer.

WARNING! Electrical Shock Hazard: Do not intentionally interrupt the protective conductor. Any interruption of the protective conductor is likely to make the installation dangerous.

Table A-3 UPS and Power Conditioner Requirements

Condition RequirementsOutput voltage 200–240 VAC True on line (double conversion)Frequency 50/60 HzWaveform Pure sine waveMinimum peak current 3 × nominal currentOutput voltage distortion

Site Requirements

System Electrical SpecificationsReturn to checklist.The following tables contain the electrical specifications for the mass spectrometer, roughing pump, mass spectrometer bench, computer, and monitor.

Note: Specifications are subject to change without notice.

Table A-4 Mass Spectrometer Electrical Specifications

Mass spectrometer ValueNominal input voltage 200 VAC to 240 VACInput voltage fluctuation ±10% of nominalFrequency 50/60 HzMax input current 10 AMax input power 1000 VA

Table A-5 Roughing Pump Electrical Specifications

Varian 849-9240 roughing pump ValueNominal input voltage 200 VAC to 240 VACInput voltage fluctuation ±10% of nominalFrequency 50/60 HzMax input current —Max input power 1200 VA

Table A-6 Optional Mass Spectrometer Bench Electrical Specifications

Optional mass spectrometer bench ValueNominal input voltage 100 VAC to 240 VACInput voltage fluctuation ±10% of nominalFrequency 50/60 HzMax input current 1 AMax input power 240 VA

Table A-7 Computer Electrical Specifications

Computer (P-390) ValueNominal input voltage 115/230 VACInput voltage fluctuation ±10% of nominalFrequency 50/60 HzMax input current 6/3 AMax input power 690 VA



Site Requirements

Gas Supply RequirementsReturn to checklist.Use high-pressure liquid nitrogen dewars or AB SCIEX approved gas generators.

Caution: Potential Instrument Damage: Each supply must be separately regulated at the mass spectrometer otherwise over pressure can damage gas controllers.It

Table A-8 Monitor Electrical Specifications

Monitor (1907FP) ValueNominal input voltage 100 VAC to 240 VACInput voltage fluctuation +6/–10% of nominalFrequency 50/60 HzMax input current 1.5 AMax input power 360 VA

Figure A-7 Gas connection configuration

Item Gas Description Requirements Tubing1 Gas 1/Gas 2 Zero air Zero grade air at 100 psi

(max.); flow rate of 22 L/min.1/4 inch

2 Curtain Gas™ supply; CAD gas

UHP (ultra high purity) nitrogen (N2)

UHP N2 at 60 psi (max.); flow rate of 10 L/min.

1/4 inch

3 Source exhaust House air, zero air, or UHP N2

House air, zero air, or UHP N2 at 55 psi; flow rate of 8 L/min. Do not operate below 55 psi.

1/4 inch

Note: All regulator output fittings must be 1/4 inch NPT to 1/4 inch Swagelok (Swagelok PN SS-400-11-4).

1

2

3

1

2

3



Site Requirements

Figure A-8 Swagelok connection and tubing

Optional GeneratorsReturn to checklist.Gas generator are available from AB SCIEX. Refer to the manufacturer’s documentation that comes with the generator for system specifications.

Ventilation and Waste-Collection RequirementsReturn to checklist.

Caution: Potential Instrument Damage: Do not connect the source exhaust hose to the vent. The connection must be made by a qualified AB SCIEX FSE.

• Provide a ventilation system with a total negative flow rate capacity of 283 L/min (10 cfm) at item 1 in Figure A-9.

• Provide a smooth fitting for the roughing pump, with an o.d. of 3.2 cm (1.25 inch). The vent must be within 1.5 m (5 ft) of the exhaust port on the roughing pump, and at least 1 m (3 ft) above the floor. Refer to Figure A-9.

• Provide a fitting for the source exhaust drain bottle with an o.d. of 1.3 cm (0.5 inch). The vent must be within 1.5 m (5 ft) of the source exhaust drain bottle. Refer to Figure A-9.

WARNING! Radiation Hazard, Biohazard, or Toxic Chemical Hazard: Make sure that the laboratory is equipped with an appropriate ventilation system. Adequate laboratory ventilation is required for safe operation of the mass spectrometer.

WARNING! Radiation Hazard, Biohazard, or Toxic Chemical Hazard: Use only qualified personnel for the installation of plumbing and ventilation fixtures, and make sure that all installations follow local bylaws and biohazard regulations.



Site Requirements

General Guidelines for the Laboratory Ventilation SystemReturn to checklist.

• Make sure that the ventilation of the laboratory environment in which the mass spectrometer will be used complies with local regulations, and that the air exchange rate is appropriate for the work performed.

• Minimize the length and number of bends in the ducting system.• Use smooth stainless steel tubing instead of flexible tubing to reduce friction loss or

drag in the ventilation system. Use 45 degree elbows to turn corners.

Figure A-9 Vent connections

Item Description1 Vent

2 Source exhaust hose: 1.3 cm (0.5 inch) i.d. (inside diameter)

3 Source exhaust drain bottle. In this drawing, the capped drain bottle is shown at the back of the mass spectrometer, to make connection points visible. The drain bottle is located at the side of the mass spectrometer when installed.

4 Source exhaust drain tubing

5 Roughing pump exhaust hose: 3.2 cm (1.25 inch) i.d.

Note: In the United States, OSHA 29 CFR Part 1910-1450 requires 4 to 12 air changes per hour in laboratories.

3

1

5

2

4



Site Requirements

• (Recommended) Equip the blower used for the source exhaust with an indicator light located near the mass spectrometer, so that the operator can easily see whether the blower is on.

• Make sure that the length of the duct that enters the blower is a straight length of at least ten times the diameter of the duct.

• Equip the outlet end of the system with a backdraft damper and an exhaust stack. Keep the exhaust outlet away from open windows or inlet vents.

• Supply a quantity of makeup air that matches the quantity of the air exhausted by the system. An airtight lab causes an efficiency loss in the exhaust system.

Network and Computer Equipment RequirementsReturn to checklist.

• Make sure that an IT specialist is available to install the security software while the FSE is present.

Caution: Potential Instrument Damage: Other than security software, do not install additional software on the computer. Changes to the configured software could void the instrument warranty and cause the system to stop operating.

Customer Printer RequirementsReturn to checklist.The system can be connected to a network or dedicated printer.

• Make sure that the printer and any necessary print drivers are available before the scheduled installation.

LAN Connection (Optional)Return to checklist.

• Make sure that an active, tested LAN connection is in place before the scheduled installation date.

• Make sure that a network specialist is available to connect the computers to your LAN while the FSE is present.



Site Requirements

Environmental RequirementsReturn to checklist.

Standard Requirements• An ambient temperature of 15°C to 30°C (59°F to 86°F)

The rate of the change in temperature should not be more than 2°C (3.6°F) per hour. Ambient temperature fluctuations may result in mass shifts in spectra.

• Relative humidity from 20 to 80%, non-condensing• The cooling and venting requirement for the mass spectrometer and roughing pump

is 6500 Btu/hr

Caution: Potential Instrument Damage: Do not place the roughing pump in an enclosed unventilated area. Otherwise, it will fail prematurely or shut down from overheating and may cause severe damage to the mass spectrometer.

Optional RequirementsWe recommend that you install a soft wall behind the mass spectrometer to reduce the reflection of sound generated by the equipment.

Sound Pressure Specifications

Vibration• The packaged instrument was tested to confirm the effects of transportation do not

impact instrument performance upon arrival at the customer destination.• AB SCIEX has no specific data that relates to instrument performance under the

effects of vibration.

Note: Operation of the mass spectrometer at altitudes higher than 2000 m (6400 ft.) above sea level may impact mass spectrometer performance.

Note: Peripheral devices may have different operating environment requirements. Check the operating environment requirements with the manufacturer of each peripheral device that will be used with the mass spectrometer.

Table A-9 Sound Pressure Levels

Sound pressure LevelAverage sound pressure level 65 dBAMaximum sound pressure level 68 dbA (at ion source)



Site Requirements

Customer Supplied Solutions and EquipmentReturn to checklist.

• HPLC-grade ammonium acetate (100 mg)• MS-grade acetonitrile (2 L)• MS-grade methanol (2 L)• HPLC-grade deionized water (2 L)• Formic acid, 99% or higher (50 mL)• LC system, including waste bottles unless ordered through AB SCIEX• Pipettors (20 µL, 100 or 200 µL, 1 mL)• Printers• Table for the computer and monitor. Refer to Layout Requirements on page 14. • Mass spectrometer bench, unless ordered through AB SCIEX

WARNING! Toxic Chemical Hazard: Follow all safety guidelines when handling, storing, and disposing of chemicals. For health and safety guidelines, see Health and Safety Precautions on page 27.



Site Requirements



B

Health and Safety Precautions

• Determine what chemicals may have been used in the instrument. Refer to Safety

Data Sheets if you are not familiar with the chemicals and the health and safety precautions that should be followed.

• Work in a well-ventilated area. • Always wear assigned personal protective equipment, including powder-free nitrile

gloves, safety glasses and a laboratory coat. • Follow required electrical safe work practices.• Avoid ignition sources when working with flammable materials, such as isopropanol,

methanol, and other flammable solvents. • Take care in the use and disposal of any chemicals. Potential risk of personal injury

if proper handling and disposing of chemicals are not followed. • Avoid skin contact with chemicals during cleaning, and wash hands after use.• Comply with all local regulations for the handling of radioactive materials.



Health and Safety Precautions



C

Equipment Safety Categories

Table C-1 Equipment Safety Categories

Description CategoryEquipment pollution degree Pollution Degree 2Mains supply transient overvoltage Overvoltage Category II



Equipment Safety Categories



Site Planning GuideContentsCustomer and FSE ResponsibilitiesCustomer Site Planner ResponsibilitiesFSE ResponsibilitiesDuring InstallationOperator Familiarization

Technical Support

Site Planning ChecklistCustomer InformationRequirementsCommentsExceptionsSignoff

Site RequirementsSite Layout RequirementsWeights and DimensionsLayout RequirementsInstallation Site Clearances

Electrical RequirementsInternational RequirementsNorth American RequirementsMains Supply FluctuationsProtective Earth ConductorUPS (Uninterruptible Power Supply)System Electrical Specifications

Gas Supply RequirementsOptional Generators

Ventilation and Waste-Collection RequirementsGeneral Guidelines for the Laboratory Ventilation System

Network and Computer Equipment RequirementsCustomer Printer RequirementsLAN Connection (Optional)

Environmental RequirementsStandard RequirementsOptional RequirementsSound Pressure SpecificationsVibration

Customer Supplied Solutions and Equipment

Health and Safety PrecautionsEquipment Safety Categories

Organization: Address: City: Country: ZIPPostal Code: Telephone: Fax: Site planner contact name: Email address: undefined: Offundefined_2: Offundefined_3: OffHigh value: Low value: undefined_4: Offundefined_5: Offundefined_6: Offundefined_7: Offundefined_8: Offundefined_9: Offundefined_10: Offundefined_11: Offundefined_12: Offundefined_13: Offundefined_14: Offundefined_15: Offundefined_16: Offundefined_17: Offundefined_18: Offundefined_19: Offundefined_20: Offundefined_21: Offundefined_22: Offundefined_23: Offundefined_24: Offundefined_25: Offundefined_26: Offundefined_27: Offundefined_28: Offundefined_29: Offundefined_30: Offundefined_31: Offundefined_32: Offundefined_33: Offundefined_34: Offundefined_35: Offundefined_36: Offundefined_37: Offundefined_38: Offundefined_39: Offundefined_40: Offundefined_41: Offundefined_42: Offundefined_43: Offundefined_44: OffComments: undefined_45: Site Planner contact name: Site Planning Review Completion Date: undefined_46: OffFSE name: FSE email: Return date:

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