Cleveland Clinic Heart and Vascular Institute presents

A Comprehensive International Symposium

The Treatment of Cardiovascular Disease: Legacy and Innovation

A Look at the Future50 years after coronary angiography40 years after coronary bypass surgeryat Cleveland Clinic

June 3-5, 2009InterContinental Hotel & Bank of America Conference CenterCleveland, Ohio

www.ccfcme.org/CardioCare09

Course OverviewThe Treatment of Cardiovascular Disease: Legacy and Innovation

3

Cleveland Clinic Heart & Vascular Institute is pleased to host this one time event which will be a

comprehensive, single-site overview of the state of cardiac surgery, cardiovascular medicine, and

their related disciplines.

This three day educational event offers a complete over-

view of current trends, ideas and innovations. Presenters

include the recognized leaders in all major aspects in

cardiovascular care from Cleveland Clinic and around the

world. Please join us as we celebrate the opening of the

Arnold and Sydell Miller Family Pavilion, the new home of

the Heart & Vascular Institute, and the largest and most

advanced heart care facility in the world.

Target Audience

This program is intended for:

• Cardiologists

• Cardiothoracic Surgeons

• Vascular Medicine Physicians

• Vascular Surgeons

• Anesthesiologists

• Internists

• Family Physicians

• Nurses

• Perfusionists

Course Objectives

Upon completion of this program, attendees should be able to identify and evaluate patients with cardiovascular disease, based on clinical guidelines and best practices for their optimal management, through the following methods:

• Reporting of the recent discoveries in atherogenesis through biomarkers and bioimaging which result in improve management of coronary artery disease

• Summarize outcomes of percutaneous Interventions for coronary, aortic, and valvular diseases

• Employ and integrate diagnostic imaging, detection and management for heart failure and transplantation

• Describe viability quantification, imaging, and future therapeutic approaches in cardiovascular disease

• Discuss the causes and consequences including the diagnosis of primary electrical diseases and devices used for cardiomyopathies

• Summarize the progress in genetics and cell regeneration

Description

www.MeetTheBuildings.com

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n Social EventYour registration fee includes the following:

Thursday, June 46:30 pm – 10:00 pm

n LocationInterContinental Hotel & Conference Center9801 Carnegie Avenue, Cleveland, Ohio 44106Phone: 216.707.4100 or 877.707.8999Fax: 216.707.4101

n Hotel ReservationsA block of rooms has been reserved at the InterContinental Hotel. To make a reservation, contact the hotel directly via phone or on-line at www.ichotelsgroup.com. Please mention the Legacy and Innovation meeting (on-line code: BC6) to receive the special rate of $189.00 per night plus tax.

Individual guest reservations must be canceled by 4:00pm (Eastern time) on the day prior to the scheduled arrival date to avoid a no-show charge.

n Ground Transportation/ParkingTaxi service is available from Cleveland Hopkins International Airport to the InterContinental Hotel. Valet parking is available at the hotel for an additional charge.

n American with Disabilities ActThe Cleveland Clinic Foundation Center for Continuing Education fully intends to comply with the legal requirements of the Americans with Disabilities Act. If you need assistance, please notify Jamie Belkin Events at 216.932.3448 at least two weeks prior to the start of this course.

n Registration/Refund PolicyGeneral registration deadline is Friday, May 29, 2009. You can register on-line at www.ccfcme.org/CardioCare09 or use the attached registration form and fax to 216.445.9406. Please register on site after May 29. A request for a refund must be received in writing by Friday, May 29, 2009. Registrations are transferable through May 29. There will be a $50 cancellation service charge. No refunds will be given after June 10, 2009.

n Grantors and ExhibitorsFor more information on grantor and exhibitor opportunities, please contact Ceca Sarkissian at 216.932.3448 or ceca@jamiebelkin.com.

n AccreditationThe Cleveland Clinic Foundation Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The Cleveland Clinic Foundation Center for Continuing Education designates this educational activity for a maximum of 20.75 AMA PRA Category 1 Credit(s).™ Physicians should only claim credit commensurate with the extent of their participation in the activity.

This activity may be submitted for American Osteopathic Association Continuing Medical Education credit in Category 2.

n For Additional InformationJamie BelkinPhone: 216.932.3448 Fax: 216.932.0444Email: jamie@jamiebelkin.com

Cleveland Clinic Campus Map

General Information

Each major building at Cleveland Clinic is designated with a letter and a corresponding color. Overhead signs throughout the buildings will help guide you.

eXAMPLeSTo locate a Clinic desk: A31Letters and corresponding color blocks indicate major areas and elevator banks

To locate a hospital room: H71-35Letters and corresponding color blocks indicate major areas and elevator banks

NOTeS■ Greeters in red coats are available to assist you.

■ Valet parking is available at the H Main Entrance, at the Crile (A) Building, Cole Eye Institute (i) and at Taussig Cancer Center (R). Patients are responsible for parking fees.

■ Information desks are indicated on the map with (?) question marks.

■ The H Main Entrance is the patient drop-off and pick-up for most buildings (F, G, H, M, S, T).

■ If you need assistance, an indoor Skyway Shuttle is available from Parking 2 (E. 100th St.) garage to and from buildings A, F, G and H.

■ Parking rates are posted at garage entrances. Discount parking passes for long-term parking are available from garage and hospital cashiers.

■ Parking Payment Stations are located in the foyer of Parking 1. There are two stations on the tunnel level and one on the ground level.

■ To exit a parking garage after 12:30 a.m. on weekdays or 10:30 p.m. on weekends, please pick up the Cleveland Clinic Police telephone at the exit. The phone will automatically ring Cleveland Clinic police.

E.93

St.

E.90

St.

E.89

St.

E.10

5 St.

E.10

2 St.

E.10

0 St.

E.10

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E.96

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6 St.

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1 St.

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St.

E.89

St.

E.87

St.

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5 St.

E.10

6 St.

Stokes Blvd.

Cedar Ave.Cedar Ave.

Carnegie Ave.

Wilbur Ave.

Carnegie Ave.

Euclid Ave.Euclid Ave.Euclid Ave.

Chester Ave.Chester Ave.

Foundation House

InterContinentalHotel Suites

E. 89th St Garage and Service Center (opening fall 2008)

Health Space WhiteMansion

BuntsAuditorium

Employee Parking

Employee Parking

Cleveland ClinicGuesthouse

Ronald McDonaldHouse

Office Complex

Taussig Cancer Center

Callahan Center

Children’s Hospital

Sydell & Arnold MillerFamily Pavilion

Main Entrance

Surgery Center

Laboratory Medicine

Meyer MRI

Emergency Medicine

Access Center

Glickman Tower

Crile Building

Cole Eye Institute

W.O. Walker Center

BankShops/Restaurants Bank

ChurchChurch

UnitedCerebral

PalsyAmerican Cancer

Society

PostOffice

DrugStore

Mellen Center

Imaging CenterCCF

Police

SubacuteCenter

InterContinental Hotel and Bank of AmericaConference Center

Imaging Center

Florist

OutpatientSurgeryCenter

Innovations

Upper Carnegie

Employee Parking

Lerner Research Institute

SherwinResearch

Betsy de WindtCancer

Labratories

Center for Genomics Research

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Parking #1 off E. 93rd St. between Chester and Euclid Ave.Parking #2 off E. 100th St. between Carnegie and Cedar Ave.Parking #3 off E. 90th St. between Carnegie and Euclid Ave.Parking #4 off E. 89th St. between Carnegie and Euclid Ave.Short-Term Parking off E. 102nd St. for Crile (A) and Cole Eye (i)

Due to construction, traffic patterns may change.Please call 216.444.9500 for a brief update or visit clevelandclinic.org/maps/constructionupdate.

For your convenience, a free shuttle bus service stops at most main building entrances. Please call 216.444.8484 or, from any house phone, 48484.Gift shop

Cleveland Clinic Main CampusDriving directions to and from campus are detailed on the front and back pages.

Specific areaof floor

Floor

A 3 1Building

Specific areaof floor

Room numberFloor

H 71 – 35Building

Each major building at Cleveland Clinic is designated with a letter and a corresponding color. Overhead signs throughout the buildings will help guide you.

eXAMPLeSTo locate a Clinic desk: A31Letters and corresponding color blocks indicate major areas and elevator banks

To locate a hospital room: H71-35Letters and corresponding color blocks indicate major areas and elevator banks

NOTeS■ Greeters in red coats are available to assist you.

■ Valet parking is available at the H Main Entrance, at the Crile (A) Building, Cole Eye Institute (i) and at Taussig Cancer Center (R). Patients are responsible for parking fees.

■ Information desks are indicated on the map with (?) question marks.

■ The H Main Entrance is the patient drop-off and pick-up for most buildings (F, G, H, M, S, T).

■ If you need assistance, an indoor Skyway Shuttle is available from Parking 2 (E. 100th St.) garage to and from buildings A, F, G and H.

■ Parking rates are posted at garage entrances. Discount parking passes for long-term parking are available from garage and hospital cashiers.

■ Parking Payment Stations are located in the foyer of Parking 1. There are two stations on the tunnel level and one on the ground level.

■ To exit a parking garage after 12:30 a.m. on weekdays or 10:30 p.m. on weekends, please pick up the Cleveland Clinic Police telephone at the exit. The phone will automatically ring Cleveland Clinic police.

E.93

St.

E.90

St.

E.89

St.

E.10

5 St.

E.10

2 St.

E.10

0 St.

E.10

0 St.

E.96

St.E.9

6 St.

E.93

St.

E.97

St.

E.10

1 St.

E.90

St.

E.89

St.

E.87

St.

E.10

5 St.

E.10

6 St.

Stokes Blvd.

Cedar Ave.Cedar Ave.

Carnegie Ave.

Wilbur Ave.

Carnegie Ave.

Euclid Ave.Euclid Ave.Euclid Ave.

Chester Ave.Chester Ave.

Foundation House

InterContinentalHotel Suites

E. 89th St Garage and Service Center (opening fall 2008)

Health Space WhiteMansion

BuntsAuditorium

Employee Parking

Employee Parking

Cleveland ClinicGuesthouse

Ronald McDonaldHouse

Office Complex

Taussig Cancer Center

Callahan Center

Children’s Hospital

Sydell & Arnold MillerFamily Pavilion

Main Entrance

Surgery Center

Laboratory Medicine

Meyer MRI

Emergency Medicine

Access Center

Glickman Tower

Crile Building

Cole Eye Institute

W.O. Walker Center

BankShops/Restaurants Bank

ChurchChurch

UnitedCerebral

PalsyAmerican Cancer

Society

PostOffice

DrugStore

Mellen Center

Imaging CenterCCF

Police

SubacuteCenter

InterContinental Hotel and Bank of AmericaConference Center

Imaging Center

Florist

OutpatientSurgeryCenter

Innovations

Upper Carnegie

Employee Parking

Lerner Research Institute

SherwinResearch

Betsy de WindtCancer

Labratories

Center for Genomics Research

P

P

P

P

P

PP

P

P

U

R

M

T

TT

S

J

JJ

HPF

G

Q

A

i

C

B

OS

E LND NA EE

NB

NE

NN NC

P

#3(closing Fall 2008)

#1

#4 (E.89 & 90 St.)

#2

SKYWAY

SKYWAY

SKYWAY

TUNNELSKYWAY

$Rx

$$P

$

$

$

v

v

v

v

?

Rx

Rx

Rx

?

??

?

??

v

v?

Rx

$

$P

Main entrance

Other entrances

Information desk

Dining area

ATM

Pharmacy

Skyway

Tunnel

Parking for disabled patientsavailable in all parking lots

Valet parking

Parking payment station

P Visitor parking (first hour of parking is free in garages only)

Parking #1 off E. 93rd St. between Chester and Euclid Ave.Parking #2 off E. 100th St. between Carnegie and Cedar Ave.Parking #3 off E. 90th St. between Carnegie and Euclid Ave.Parking #4 off E. 89th St. between Carnegie and Euclid Ave.Short-Term Parking off E. 102nd St. for Crile (A) and Cole Eye (i)

Due to construction, traffic patterns may change.Please call 216.444.9500 for a brief update or visit clevelandclinic.org/maps/constructionupdate.

For your convenience, a free shuttle bus service stops at most main building entrances. Please call 216.444.8484 or, from any house phone, 48484.Gift shop

Cleveland Clinic Main CampusDriving directions to and from campus are detailed on the front and back pages.

Specific areaof floor

Floor

A 3 1Building

Specific areaof floor

Room numberFloor

H 71 – 35Building

Course OverviewThe Treatment of Cardiovascular Disease: Legacy and Innovation

5

Christopher Bajzer, MD

John Bartholomew, MD

Edwin Beven, MD

Eugene Blackstone, MD

Manuel Cerqueira, MD

Leslie Cho, MD

Mina Chung, MD

Daniel Clair, MD

Milind Desai, MD

Thomas Dresing, MD

M. Bridget Duffy, MD

Matthew Eagleton, MD

Stephen Ellis, MD

Scott Flamm, MD

A. Marc Gillinov, MD

Marcelo Gomes, MD

Gonzalo Gonzalez-Stawinski, MD

Steven Gordon, MD

Heather Gornik, MD

Roy Greenberg, MD

Brian Griffin, MD

Richard Grimm, DO

Michael Hanna, MD

Stanley Hazen, MD

Norman Hertzer, MD

Robert Hobbs, MD

Katherine Hoercher, RN

Eileen Hsich, MD

Julie Huang, MD

Wael Jaber, MD

Mohamed Kanj, MD

Samir Kapadia, MD

Harry Lever, MD

A. Michael Lincoff, MD

Bruce Lindsay, MD

Floyd D. Loop, MD

Sean Lyden, MD

Bruce W. Lytle, MD

Kandice Marchant, MD, PhD

David Martin, MD

David Mason, MD

Tara Mastracci, MD

Ellen Mayer-Sabik, MD

Tomislav Mihaljevic, MD

Rocio Moran, MD

Christine Moravec, PhD

Wilfred Mullens, MD

Sudish Murthy, MD, PhD

Stephen Nicholls, PhD

Steven Nissen, MD

Marc Penn, MD, PhD

Gosta Pettersson, MD, PhD

Leo Pozuelo, MD

Javier Provencio, MD

Michael Rocco, MD

L. Leonardo Rodriguez, MD

Eric Roselli, MD

Joseph Sabik, MD

Walid Saliba, MD

Mark Sands, MD

Timur Sarac, MD

Nicholas Smedira, MD

Edward Soltesz, MD

Sunita Srivastava, MD

Randall Starling, MD, MPH

William Stewart, MD

Lars Svensson, MD, PhD

Wilson Tang, MD

David O. Taylor, MD

Patrick Tchou, MD

James Thomas, MD

E. Murat Tuzcu, MD

David Van Wagoner, PhD

Oussama Wazni, MD

Bruce Wilkoff, MD

James Young, MD

Cleveland Clinic Faculty

Faculty Disclosure The Cleveland Clinic Foundation Center for Continuing Education has implemented a policy to comply with the current Accreditation Council for Continuing Medical Education Standards for Commercial Support requiring resolution of all faculty conflicts of interest. Faculty declaring a relevant commercial interest will be identified in the activity syllabus.

6

Eric Bates, MD University of Michigan Ann Arbor, MI

Ramon Berguer, MD, PhD University of Michigan Ann Arbor, MI

Deepak Bhatt, MD Brigham and Womens Hospital Boston, MA

William Boden, MD University at Buffalo Buffalo, NY

Robert Bonow, MD Northwestern University Medical School Chicago, IL

Michael Bristow, MD, PhD University of Colorado Aurora, CO

Richard Paul Cambria, MD Massachusetts General Hospital Boston, MA

Blase Carabello, MD Veterans Affairs Medical Center Houston, TX

John Carroll, MD University of Colorado Denver, CO

Timothy Chuter, MD University of California, San Francisco San Francisco, CA

Anthony Comerota, MD Toledo Hospital Toledo, OH

John Conte, MD Johns Hopkins Baltimore, MD

Jack Copeland, MD Arizona Health Sciences Center Tucson, AZ

Tirone David, MD Toronto General Hospital Toronto, ON

N. A. Mark Estes, III, MD Tufts University School of Medicine Boston, MA

Derek Exner, MD University of Calgary Calgary, AB, Canada

Michael Felker, MD Duke Clinical Research Institute Durham, NC

Mario Garcia, MD Mount Sinai Medical Center New York, NY

Bruce Gray, DO Upstate Vascular Associates Greenville, SC

David Holmes, MD Mayo Clinic Rochester, MN

Eric Isselbacher, MD Massachusetts General Hospital Boston, MA

Michael Jaff, DO Massachusetts General Hospital Newton, MA

K. Wayne Johnston, MD Toronto General Hospital Toronto, Onterio, Canada

Nicholas Kouchoukos, MD Missouri Baptist Medical Center Saint Louis, MO

Albrecht Kramer, MD Catholic University Hospital Santiago, Chile

Irving Kron, MD University of Virginia Charlottesville, VA

Michael Lauer, MD National Heart Lung and Blood Institute Bethesda, MD

Wayne Levy, MD University of Washington Seattle, WA

Kenneth McCurry, MD University of Pittsburgh Pittsburgh, PA

Ruth McPherson, MD, PhD University of Ottowa Heart Institute Ottawa, ON, Canada

D. Craig Miller, MD Stanford University Medical School Stanford, CA

Leslie Miller, MD Georgetown University Hospital and Washington Hospital Center Washington, DC

Hiroshi Nakagawa, MD, PhD University of Oklahoma Health Sciences Center Oklahoma City, OK

Christopher O’Connor, MD Duke Medical Center Durham, NC

Jeffrey Olin, DO The Heart and Vascular Institute Morristown, NJ

Richard Page, MD University of Washington Seattle, WA

Juan Parodi, MD University of Miami Miami, FL

Vivek Reddy, MD University of Miami Miami, FL

Paul Ridker, MD Harvard Medical School, Center for Cardiovascular Disease Prevention, Brigham and Women’s Hospital Boston, MA

Yoram Rudy, PhD Washington University St. Louis, MO

Hazim Safi, MD Memorial Hermann Houston, TX

Hartzell Schaff, MD Mayo Clinic Rochester, MN

Mark Slaughter, MD University of Louisville Louisville, KY

Benjamin Sun, MD The Ohio State University Medical Center Columbus, OH

Michael O. Sweeney, MD Brigham and Women’s Hospital Chestnut Hill, MA

Paul Teirstein, MD Scripps Clinic and Research Foundation La Jolla, CA

Jeffrey Weitz, MD Henderson Research Centre Hamilton, ON, Canada

Guest Faculty

Course OverviewThe Treatment of Cardiovascular Disease: Legacy and Innovation

7

W E D n E s D Ay | J u n E 3 , 2 0 0 98:00 - 8:10am Welcome

Delos M. Cosgrove, MD, CEO and President Cleveland Clinic

8:10 - 8:40am Keynote Address Floyd D. Loop, MD*

8:40 - 10:25am CORONARY ARTERY DISEASE PLENARY Moderators: Stephen Ellis, MD and Joseph Sabik, MD

• Debate: DES, BMS, or Medical Therapy in Stable Ischemic Heart Disease William Boden, MD and David Holmes, MD

• Evaluating Percutaneous Interventions for Traditional Surgical Indications Paul Teirstein, MD

• Perioperative Risk of Patients with Previous DES Placement Stephen Ellis, MD

• What’s New in Coronary Surgery? Joseph Sabik, MD

• Preventing Clots in Ischemic Heart Disease A. Michael Lincoff, MD

10:25 - 10:45am Break

10:45 - 12:30pm PREVENTION PLENARY Moderators: Stanley Hazen, MD, PhD and Leslie Cho, MD

•PlaqueRegression:CanWeMake Atherosclerosis Go Away? Steven Nissen, MD

•HDLTargetedTherapy—WhichDrugs and Why Stanley Hazen, MD, PhD

•DoesNon-InvasiveImagingPreventDeath? Moderator: TBA • Pro – Mario Garcia, MD • Con – Michael Lauer, MD Panel Discussion Michael Lauer, MD, Stephen Nicholls, MD, Leslie Cho, MD, Mario Garcia, MD

12:30 - 2:00pm Lunch Keynote Addresses Improving the Patient Experience in Cardiovascular Care: More Than Reducing Mortality! M. Bridget Duffy, MD*

Edwin Beven, MD*

2:00 - 3:30pm CONCURRENT SESSIONS

Valve: Minimally Invasive Mitral Repair Moderators: A. Marc Gillinov, MD and Robert Bonow, MD

• Anterior Leaflet Repair Tirone David, MD

• Robotic Mitral Repair Tomislav Mihaljevic, MD

• MinimallyInvasiveMitralRepair—IsItBetter? A. Marc Gillinov, MD

• Surgery for Ischemic Mitral Regurgitation Irving Kron, MD

Coronary Artery Disease: Management of Acute MI and Shock Moderator: A. Michael Lincoff, MD

• Delays in Door-to-Balloon Time and the Impact on Choice of Therapy Eric Bates, MD

•CABG in Cardiogenic Shock: Patient Selection Joseph Sabik, MD

• Circulatory Support in the Cath Lab: Saving Lives or Spending Money Samir Kapadia, MD

Aortic: Imaging and Patient Workup Moderator: Eric Roselli, MD

• Advances in Aortic CT Imaging Scott Flamm, MD

• Comprehensive Work Up of Aortic Patients Eric Isselbacher, MD

• Follow-up Paradigms: Small Aneurysms, Dissections, and Endografts Tara Mastracci, MD

• Marfans and Other Genetic Disorders: Implications and Testing Efforts Rocio Moran, MD

Heart Failure: Controversies in Heart Failure Care Moderators: Katherine Hoercher, RN and Eileen Hsich, MD

• Is Tailored Therapy with a PA Catheter Beneficial? • Pro – Wilson Tang, MD • Con – Michael Felker, MD

• Heart Transplant Center Volume: Does Size Matter for Quality Outcomes? • Pro – John Conte, MD • Con – Benjamin Sun, MD

*Speaker’s address is Non-CME.

8

• Does Exercise Help Patients with Heart Failure? • Pro – Christopher O’Connor, MD • Con – Michael Lauer, MD

Prevention: What is the Role of Alternative Blood and Genetic Markers in Preventive Cardiology? Moderator: Stanley Hazen, MD, PhD

• Blood Markers Paul Ridker, MD

• Genetic Markers Ruth McPherson, MD, PhD

Electrophysiology: Atrial Fibrillation: Pathophysiology Moderators: Patrick Tchou, MD and Oussama Wazni, MD

• Genotyping & Phenotyping, How Do We Get Here? Mina Chung, MD

• Cellular Insights into Atrial Fibrillation David Van Wagoner, MD

• Role of the Autonomic Nervous System Hiroshi Nakagawa, MD

• Insights from Noninvasive ECG Imaging (ECG) Yoram Rudy, PhD

Panel Discussion

4:00 - 5:30pm CONCURRENT SESSIONS

Electrophysiology: Atrial Fibrillation: Management Moderators: Thomas Dresing, MD and Walid Saliba, MD

• Rate vs. Rhythm Control: The Ongoing Struggle Richard Page, MD

• New Imaging & Navigation Modalities Vivek Reddy, MD

• Surgical Ablation: When, Why and How? A. Marc Gillinov, MD

• Monitoring for Outcomes: Implanted, Wearable Bruce Lindsay, MD

Panel Discussion

Coronary Artery Disease: Technical Advances in PCI Moderator: Stephen Ellis, MD

• PCI for Chronic Total Occlusion Samir Kapadia, MD

• Magnetic Resonance Guided PCI TBD

• The Role of Rotational Angiography John Carroll, MD

Heart Failure: Treatment of Advanced Cardiopulmonary Failure Moderators: Kenneth McCurry, MD and Michael Hanna, MD

• Advanced Lung Failure: ECMO Bridge to Lung Transplant David Mason, MD

• Pulmonary Hypertension: When to Choose Heart Transplant, Heart/Lung Transplant or VAD Support Kenneth McCurry, MD

• ArtificialLungTechnology—AreWeClose? Sudish Murthy, MD, PhD

Case Presentation

Imaging for Viability: Why is it Important? Moderator: James Thomas, MD

• Echo Wael Jaber, MD

• Nuclear Manuel Cerqueira, MD

• CT/Cardiac MRI Mario Garcia, MD

Vascular: Management of Venous Thromboembolism (VTE) Diagnosis and Management of Acute PE Moderator: Marcelo Gomes, MD

• Standard Anticoagulation for VTE John Bartholomew, MD

• Thrombolytic Therapy for Acute PE Jeffrey Weitz, MD

• Thrombolytic Therapy/Intervention for DVT Anthony Comerota, MD

• Pulmonary Embolectomy Gonzalo Gonzalez-Stawinski, MD

• Newer Anticoagulants Jeffrey Weitz, MD

• Thrombophilia (Genetic/Acquired) Kandice Marchant, MD, PhD

Aortic: How I Do It Moderator: Bruce W. Lytle, MD

• ETG Open and Hybrids Lars Svensson, MD, PhD

• TAAA Branch Grafts Roy Greenberg, MD

Course OverviewThe Treatment of Cardiovascular Disease: Legacy and Innovation

9

• ETA Completion Eric Roselli, MD

• Aortic Dissection Edward Soltesz, MD

T H u r s D Ay | J u n E 4 , 2 0 0 98:00 - 9:45am VALVULAR DISEASE PLENARY

Mitral Valve: Case Studies Moderators: A. Marc Gillinov, MD and William Stewart, MD

• Asymptomatic4+MRwithProlapse— Should We Operate? Robert Bonow, MD

• RepairofIschemicMR—theSubstrateand the Challenges D. Craig Miller, MD

• PercutaneousRepairforMR—Readyfor Prime Time? Blase Carabello, MD

Aortic Valve: Case Studies Moderators: Tirone David, MD and E. Murat Tuzcu, MD

• TranscatheterAVR—WhichPatients, Which Approach? Samir Kapadia, MD

• Valve-SparingRootSurgery—WhatHas Time Taught Us? Tirone David, MD

• TissueValvesinYoungPatients—The Right Choice? Nicholas Smedira, MD

• The Treatment of Valve Endocarditis Gosta Pettersson, MD, PhD

9:45 - 10:15am Break

10:15 - 12:00pm AORTIC PLENARY Moderators: Roy Greenberg, MD and Bruce W. Lytle MD

• Past, Present, and Future Concepts for AAA Repair Juan Parodi, MD

• Contrast Between Open and Endovascular Repair Of Thoracoabdominal Aneurysms Roy Greenberg, MD

• Hybrid Graft Solutions and Brain Protection for Arch Repair Lars Svensson, MD, PhD

Panel Discussion

12:00 - 1:30pm Lunch Keynote Addresses Regulation and Innovation Steven Nissen, MD

The Future of Information Technology and Patient Care Eugene Blackstone, MD

1:30 - 3:15pm VASCULAR PLENARY Moderators: John Bartholomew, MD and Matthew Eagleton, MD

Is Intervention Better than Drugs? Asymptomatic Carotid Artery Stenosis (Debates)

• CEA is the Gold Standard Norman Hertzer, MD

• Carotid Stenting is the First line of Therapy Daniel Clair, MD

• MedicalTherapy—NoCaseforIntervention Michael Jaff, DO

Panel Discussion

Non-Lifestyle Limiting Claudication (Debates)

• Intervention Indicated in the Endovascular Era Bruce Gray, DO

• Medical Management is the Only Therapy Heather Gornik, MD

Panel Discussion

3:15 - 3:45pm Break

3:45 - 5:15pm CONCURRENT SESSIONS

Coronary Artery Disease: The Gold Standard in the Treatment of CAD: PCI vs. CABG Moderators: A. Michael Lincoff, MD and Joseph Sabik, MD

• What is the Data on Restenosis? David Holmes, MD

• What is the Data on Graft Patency? Joseph Sabik, MD

Case Presentations: Surgery vs. Stents vs. Medicine

Valve: Advances in Imaging and Assessment of Valvular Heart Disease Moderators: Blase Carabello, MD and D. Craig Miller, MD

• Quantitative Doppler in MR: Threshold for Repair William Stewart, MD

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• 3D Echo in Valve Disease James Thomas, MD

• Quantitative Doppler in AR: Threshold for Surgery Robert Bonow, MD

• Imaging in Aortic Valve Repair Brian Griffin, MD

Aortic: Moderators: Roy Greenberg, MD and Eric Roselli, MD

• Debate: Open Versus Endovascular Repair for Infrarenal AAA Tara Mastracci, MD vs. K. Wayne Johnston, MD

• Debate: Open Versus Endovascular Thoracoabdominal Aneurysm Repair Hazim Safi, MD vs. Timothy Chuter, MD

• Debate: Open Versus Endovascular Descending Thoracic Aneurysm Repair Richard Cambria, MD vs. Nicholas Kouchoukos, MD

Vascular: Management of Lower Extremity Arterial Disease Moderator: Heather Gornik, MD

• PAD and Unusual Vasculopathies Jeffrey Olin, MD

• Imaging (Ultrasound, MRA, CTA, Ateriography) Mark Sands, MD

• SFA Stents versus PT Timur Sarac, MD and Albrecht Kramer, MD

• Tibial Recanalization Sean Lyden, MD

• Management of the Non-Revascularizable Patient Jeffrey Olin, MD

Heart Failure: Ventricular Assist Devices as a Therapy for Advanced Heart Failure Moderators: Jack Copeland, MD and James Young, MD

• The Evolution of VADS: Past, Present and Future Jack Copeland, MD

• What Have We Learned About Continuous Flow Pumps? Mark Slaughter, MD

• Current Outcomes Randall Starling, MD, MPH

• Can VADs and Medicines Facilitate LV Recovery? Leslie Miller, MD

Hypertrophic Obstructive Cardiomyopathy Moderator: Harry Lever, MD

• Clinical Aspects of HOCM Harry Lever, MD

• Imaging in HOCM Milind Desai, MD

• Percutaneous Therapy for HOCM E. Murat Tuzcu, MD

• Surgical Therapy for HOCM Hartzell Schaff, MD

• Mitral Valve Surgery for HOCM Nicholas Smedira, MD

6:30pm Social Event

F r I D Ay | J u n E 5 , 2 0 0 98:00 - 9:45am ELECTROPHYSIOLOGY PLENARY

Collaborative Approach to Electrical Therapy of Heart Failure: Moderators: Bruce Lindsay, MD and Robert Hobbs, MD

Identification of Patients at Risk of Preventable Cardiac Death: What is the Best Strategy?

• Who Dies, When and How? N.A. Mark Estes, III, MD

• LV Function, LV Scar & Dyssynchrony Milind Desai, MD

• Electrical Measurements & Derivative Derek Exner, MD

Discussion of Best Strategies

Implementation of Collaborative Electrical Therapy

• Bringing the Preop Assessment into the EP Lab Richard Grimm, DO

•TroubleshootingOptimizedCRT Wilfried Mullens, MD

• Remote Disease Management 2.0 Bruce Wilkoff, MD

9:45 - 10:15am Break

Course OverviewThe Treatment of Cardiovascular Disease: Legacy and Innovation

11

10:15 - 12:00pm HEART FAILURE PLENARY

Therapy for Heart Failure: Today and Tomorrow Moderators: Nicholas Smedira, MD and Randall Starling, MD, MPH

• Risk Stratification: Do We Need a Heart Transplant Allocation Score? Wayne Levy, MD

• Stem Cell Therapies for Acute and Chronic Heart Failure: Options for Today and Tomorrow Marc Penn, MD, PhD

• Medical Therapies and Personalized Delivery of Care with Genomics Michael Bristow, MD, PhD

• Current Indications and Outcomes in Heart and Lung Transplantation David O. Taylor, MD

12:00 - 1:30pm Lunch Keynote Address Bruce W. Lytle, MD*

1:30 - 3:30pm CONCURRENT SESSIONS

Valve: Percutaneous Valve Technologies Moderator: Blase Carabello, MD

• ApicalAVR—HowtoDoIt Lars Svensson, MD, PhD

• TransfemoralpercutaneousAVR— How to Do It E. Murat Tuzcu, MD

• Transcatheter AVR will Change the Practice of Valve Disease Blase Carabello, MD

• Percutaneous Repair for MR: How Long Until It’s Ready? Samir Kapadia, MD

• Imaging for Percutaneous AVR and MV Repair L. Leonardo Rodriguez, MD

Vascular: Management of Cerebral Vascular Disease Moderator: Matthew Eagleton, MD

• CarotidDuplex—TheGoldStandard Heather Gornik, MD

• Cerebral Protection Devices Christopher Bajzer, MD

• Vertebral Interventions: The Ignored Problem Ramon Berguer, MD, PhD

• Percutaneous Vertebral Interventions Sunita Srivastava, MD

• Unusual Carotid Disorders Michael Jaff, DO

Prevention: Ask the Experts Moderator: Leslie Cho, MD

• Complex Lipid Cases Michael Rocco, MD, and Stanley Hazen, MD, PhD

• Women and Heart Disease Leslie Cho, MD, Julie Huang, MD, Ellen Mayer-Sabik, MD

Heart-Brain Medicine Moderator: Marc Penn, MD, PhD

• State of the Science Marc Penn, MD, PhD

• Subarchnoid Hemorrhage and Sudden Cardiac Death Javier Provencio, MD

• The Risk of Depression in the CABG Population Leo Pozuelo, MD

• The Role of Biofeedback in the Treatment of Heart Failure Christine Moravec, PhD

Electrophysiology: Collaborative Management of Device Therapy Morbidity: Prevention, Protection & Therapy Moderators: David Martin, MD and Mohamed Kanj, MD

• ICD Shocks: Causes, Prevention & Risk Michael O. Sweeney, MD

• Vascular Occlusion: Detection & Therapy Deepak Bhatt, MD

• Infection: Pathophysiology, Prophylaxis & Therapy Steven Gordon, MD

• Lead Failure: Pathophysiology, Prevention & Detection Bruce Wilkoff, MD

3:30pm Meeting Adjourns

*Speaker’s address is Non-CME.

The Treatment of Cardiovascular Disease: Legacy and InnovationInterContinental Hotel and Bank of America Conference Center June 3-5, 2009

registration Form

Wednesday, June 312:30 – 2:00pm Lunch – Edwin Beven, MD

2:00 – 3:30pm Valve: Minimally Invasive Mitral Repair

Coronary Artery Disease: Management of Acute MI and Shock

Aortic: Imaging and Patient Workup

Heart Failure: Controversies in Heart Failure Care

Prevention: What is the Role of Alternative Blood and Genetic Markers in Preventive Cardiology?

Electrophysiology: Atrial Fibrillation: Pathophysiology

4:00 – 5:30pm Electrophysiology: Atrial Fibrillation: Management

Coronary Artery Disease: Technical Advances in PCI

Heart Failure: Treatment of Advanced Cardiopulmonary Failure

Imaging for Viability: Why is it Important?

Vascular: Management of Venous Thromboembolism (VTE) Diagnosis and Management of Acute PE

Aortic: How I Do It

Thursday, June 412:00 – 1:30pm Lunch – Steven Nissen, MD | Eugene Blackstone, MD

3:45 – 5:15pm Coronary Artery Disease: The Gold Standard in the Treatment of CAD: PCI vs. CABG

Valve: Advances in Imaging and Assessment of Valvular Heart Disease

Aortic

Vascular: Management of Lower Extremity Arterial Disease

Heart Failure: Ventricular Assist Devices as a Therapy for Advanced Heart Failure

Hypertrophic Obstructive Cardiomyopathy

Friday, June 512:00 – 1:30pm Lunch – Bruce W. Lytle, MD

1:30 – 3:30pm Valve: Percutaneous Valve Technologies

Vascular: Management of Cerebral Vascular Disease

Prevention: Ask the Experts

Heart-Brain Medicine

Electrophysiology: Collaborative Management of Device Therapy Morbidity: Prevention, Protection & Therapy

Pre-Registration Due by May 29, 2009Complete the information below if registering by MAIL or FAX

First Name ____________________________________________________________________

Last Name ____________________________________________________________________

Affiliation _____________________________________________________________________

Degree__________________________________ Specialty _____________________________

Address _______________________________________________________________________

City_____________________________________ State___________ Zip __________________

Phone___________________________________ Fax _________________________________

Email Address _________________________________________________________________

Register online at: www.ccfcme.org/CardioCare09

Fee includes: registration materials, social event, meals, and sessions

To pay by check: Make payable to Cleveland Clinic and mail to:The Cleveland Clinic Educational Foundation

PO Box 931653Cleveland, OH 44193-1082To Register by fax: 216-445-9406

CCF Main Campus, Family Health Centers, CCHS Community Hospital employees (physicians and non-physicians) and CCF alumnus should register at www.ccfcme.org/CardioCare09. Once you register online, please DO NOT mail or fax in a registration form.

Heart and Vascular Institute Professional Staff and Symposium attendees coming from outside the U.S. will receive complimentary registration. Please register at www.ccfcme.org/CardioCare09.

Concurrent SessionsPlease designate the sessions you would like to attend by checking the box next to the session. Please sign up for only one session during each concurrent breakout time.

Full Course Brochure Online Per Day

Physician $450.00 same $185.00

Comprecare Affiliate (Member ID #___________) $292.50 same $120.25

Resident/Fellow/Nurse $75.00 same $52.00

Corporate $600.00 same $235.00

CCF Alumnus complimentary —

International Physician complimentary —

Total amount enclosed or to be charged $__________________________

Make check payable to: The Cleveland Clinic Educational Foundation

Or charge the following account:

Mastercard Visa Discover American Express

Card Number Expiration Date

Signature (not valid without signature)

3/4-digit verification number (found on the back of the card)

I require vegetarian meals.

I will attend the Social event on June 4, 2009.

Course020541•OfficeUseOnly

Fee _____________Date ___________ M.O.P. ____________ CXL/Fee _____________

Cleveland Clinic Heart and Vascular Institute presents

A Comprehensive International Symposium

The Treatment of Cardiovascular Disease: Legacy and Innovation

June 3-5, 2009InterContinental Hotel & Bank of America Conference CenterCleveland, Ohio

In celebration of the opening of our new Heart Center and more importantly to celebrate our rich legacy of cardiovascular care and innovation, Cleveland Clinic Heart and Vascular Institute will host this one time CME event: The Treatment of Cardiovascular Disease: Legacy and Innovation, June 3-5, 2009.

Join us for this landmark educational event of internationally renowned faculty and decision makers in the field of heart and vascular disease.

Sessions will include: · Aortic Disease · Coronary Artery Disease · Valvular Disease · Electrophysiology · Heart Failure · Prevention · Imaging · Heart-Brain Medicine · Vascular Disease · Transplantation

The Cleveland Clinic Foundation 9500 Euclid Avenue / JJ40Cleveland, OH 44195

This activity has been approved for AMA PRA Category 1 Credit™.