Guided By:Ms. Ruchita PatelPresented By :Abhinandan Sharma & Vaibhav Trivedi INTRODUCTIONLab-n-a-chi! "L#$% is a device that inte&rates ne r several labratry 'unctins n a sin&le chi! ' nly millimetres t a 'e( s)uare centimetres in si*e.L#$s deal (ith the handlin& ' e+tremely small 'luid vlumes d(n t less than !ic-litres. Lab-n-a-chi! devices are a subset ' M,MS devices and 'ten indicated by -Micr Ttal Analysis Systems- ".TAS% as (ell.The micr 'luidic lab-n-a-chi! all(s t cnduct chemical & bichemical analysis inaminiaturi*ed'rmatssmallthat!r!ertiesande''ectsaresuccess'ully enhanced/and!rcessesseamlesslyinte&rated.Thismicrscaleadvanta&e translates int &reater sensitivity/ mre accurate results/ and better in'rmatinAdvancesinmicr'luidicstechnl&y''ere+citin& !ssibilities'r01Ase)uencin&/!rteincrystalli*atin/ dru&discvery/immunassays&!int-'-careclinical dia&nstics/ etc.CHIP MATERIAL & FABRICATION TECHNOLOGYThe basis 'r mst L#$ 'abricatin !rcesses is !htlith&ra!hy.Because ' demands 'r e.&. s!eci'ic !tical characteristics/ bi- r chemical cm!atibility/ l(er !rductin csts and 'aster !rtty!in&/ ne( !rcesses have been devel!ed such as &lass/ ceramics and metal etchin&/ de!sitin and bndin&/ P0MS !rcessin& "e.&./ s't lith&ra!hy%/ thic2-'ilm- and stere-lith&ra!hy.DISPOSABLE CHIPThe chi! (ill be 'abricated 'rm a bicm!atible !lymer such as PMMA/ usin& RTP "ra!id thermal !rcess% in3ectin mldin&.The trans!arent !lastic cnstructin is (ell-suited 'r !tical detectin techni)ues/ and assures that such chi!s (ill be relatively a''rdable in (hen !rduced in vlume.4i&ure 5 sh(s a cnce!tual three-layer chi! desi&n/ cnsistin& ' a multi!le-reservir base layer "a% t (hich a 'unctinal 'luidic layer/ "b% and a thin cver layer"c% are bnded.CONSTRUCTION & WORKINGBase unit :- The 6B$ cunter cnsists ' t( cm!nents: an ine+!ensive dis!sable chi! n (hich all micr 'luidic interactins ccur/ and a hand-held base unit.. A bld sam!le is dra(n/ the chi! is inserted int the base unit/ and the 6B$ cuntin& !rcess be&ins. Reservir :- 7t includes varius sectins ' chi! (here!ressuri*ed &as/ antica&ulants/ !er+ide and ther stains are stred.#btainin& bld sam!le :- A small hy!dermic needle inte&rated int the chi! !ermits bld sam!le ac)uisitin by ca!illary actin. T! vie( ' a !r!sed lab-n-a-chi!.Sam!le 'cusin& :- ,lectr-smsis !lays a 2ey rle in cntrllin& sam!le 'l( in the sam!le 'cusin& sectin ' the chi! "a clse-u! vie( ' this re&in is sh(n in 4i&ure %. ADVANTAGESl( 'luid vlumes cnsum!tin 'aster analysis and res!nsebetter !rcess cntrlcm!actness ' the systems DISADVANTAGESnvel technl&y and there're nt yet 'ully devel!ed.detectin !rinci!les may nt al(ays scale d(n in a !sitive (ay/ leadin& t l( si&nal-t-nise ratis.althu&h the abslute &emetric accuracies and !recisin in micr 'abricatin are hi&h/ they are 'ten rather !r in a relative (ay/ cm!ared t !recisin en&ineerin& 'r instance.APPLICATIONSReal-time !cr: detect bacteria/ viruses and cancers.0ielectr!hresis: detectin ' cancer cells and bacteria.Bld sam!le !re!aratin: can crac2 cells t e+tract 01A.CONCLUSIONThe advanta&e ' 'ast am!li'icatin ' 01A detectin ' cancer cell r sendin& ' nan device in bld stream t destry tumr cell and &ive relie' t cancer !atient ma2es Lab n chi! mre 'uturistic.Thus seein& Lab n chi! as an im!rtant yet cmmn device (uld nt be e+clamatin 'r 'uture medical 'ield. 8sin& ne( inventin and re!lacin& lder nt nly &ives mre accuracy but asl saves mney and time.6ecnclude that Lab n chi! is the 'uture ' bimedical science. The technl&y used in Lab n chi! is 2n(n as 1an technl&y (hich re)uires very less v9ume ' bld as a sam!le 'r detectin ' any disease r !hysil&y !arameter. 7t user 'riendly as (ell as can be used by anyne and at anytime and !rvides results in s!lit secnds r minutes.Any Quest!n "