13.Haemorrhage,Classification,Diagnosis,Management,Blood Transfusion c

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    Professor Panna Lal SahaProfessor of Surgery & Head

    Department of SurgeryGC Trust Medical CollegeChittagong

    Haemorrhage classificationdiagnosis management blood

    transfusion

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    Definition

    Escape of circulating blood from the

    vascular system.

    60-70 percent of the blood volume is

    accommodated in low pressure

    venules and veins and in the

    sphlanchnic vessels, and a loss of upto 10% (500-600ml) is adequately

    compensated for by the

    venoconstriction and therefore the

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    Signs

    External blood loss is

    obvious, but a serious

    internal hemorrhage must berecognized without delay by

    the general signs of bloodloss:

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    Signs

    Restlessness

    Increasing

    pulse rateDecreased

    blood pressure

    Increasing

    pallor

    Deep sighing

    respiration

    Cold and

    clammy skin

    Empty veins

    Thirst, tinnitusand blindness

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    Effects

    Blood loss threatens the oxygen supply to

    tissue cells

    Pending the arrest of hemorrhage and the

    replacement of blood, the function of vital

    structures such as the heart and brain stemis largely preserved by the increasing pulse

    rate peripheral vasoconstriction

    Unchecked and untreated blood loss resultsin failure of the heart and vasomotor centre

    to maintain a sufficient perfusion of oxygen

    for their own purposes and death follows.

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    Effects

    Vasoconstriction fails to maintain theblood pressure when blood loss

    increases beyond 20-30%

    Hypotension becomes severe with a50% loss and the perfusion of

    myocardium and brain stem is affected.

    Thus the heart fails and vasoconstrictionof venous reservoir fails each affecting

    the others in a vicious cycle which ends

    in death

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    Natural blood volume and red cell

    recovery

    The recovery of blood volumesbegins immediately by thewithdrawal of fluid from the tissues

    from the circulation. There ishemodilution. Plasma proteins arereplaced by the liver

    Red cell recovery takes some fiveto six weeks

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    Chronic hemorrhage

    Examples of causes in surgical practiceare bleeding hemorrhoids, fibroids,

    carcinoma colon, peptic ulcer etc.

    There is no diminution of blood volumeas there is time for plasma

    replacements, but red cell replacement

    lags behind resulting in a state ofanaemic hypoxia, requiring an increased

    cardiac out put.

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    Chronic hemorrhage

    These patients develop high outputcardiac failure

    They must not be transfused with

    normal blood, but require packed

    cells instead.

    Acute hemorrhage in such cases ispoorly compensated, as oxygen

    carriage is already depleted.

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    Measurement of hemorrhage

    Bed side observation

    Record keeping

    Hemoglobin level

    The hematocrit Measuring blood loss

    Blood clot

    Swelling in closed fracture

    Swab weighing Blood volume determination

    Measurement of CVP

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    Pressure and packing

    Pressure dressing to be applied inthe wound

    Simple pressure over the bleeding

    site by finger stop bleeding

    Packing by roll gauge is an

    important tool to control bleeding inspecial circumstance

    Tourniquets applied in special place

    and circumstance to stop bleeding

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    Position and rest

    Elevation of limbs

    Position of patient during

    operationAbsolute rest

    Sedation

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    Hemorrhage management during

    operation

    Artery forceps

    Bleeding vessels are ligated with cat gut,

    silk, vicryl, etc. or coagulated with

    diathermy. Management of scalp hemorrhage during

    operation by special technique

    Pressure by gauze pack helps to stopoozing

    Gel-foam or oxygel application stops

    bleeding in special circumstance

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    Blood transfusion

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    Indication of blood transfusion in

    surgical practice

    Following traumatic incidentswhere there has been severe

    blood loss, or hemorrhage frompathological lesion, e.g. from

    gastrointestinal tract

    During major operativeprocedures where a certain

    amount of blood loss is inevitable,

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    Preparation of blood products

    It is important that blood donors should befit and no history of serious diseases, in

    particular hepatitis, AIDS, malaria which

    are transmitted in donor blood Blood is collected into a sterile

    commercially prepared plastic bag with

    needle and plastic tube attached in a

    complete, closed sterile unit

    Usually 410 ml blood is collected from a

    donor and mixed with 75 cc anticoagulant

    (CPD).

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    Infectious Disease Testing of Blood Donations

    1. Syphilis Testing - TPHA

    2. Viral Serology Testing

    - HBsAg, HCV Ab, HIV-1&2 Ab

    3. NAT Testing

    - HIV/HCV/HBV

    4. Bacterialtesting forplatelets5. Malaria testing

    for at-risk donors

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    BLOOD STORAGE

    It is essential to store blood at 4 2 C

    WBC- rapidly destroyed in stored

    blood

    Platelets at 4 C survival of platelets

    considerably reduced

    Clotting factors like platelets,

    clotting factors VIII and V are labile

    and their level falls quickly

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    Giving blood

    Selection and preparation of the site

    Careful checking of the donor blood. This

    should bear a compatibility label stating the

    patientsname, hospital reference no., wardand blood group.

    Insertion of needle or canula. The latter may

    be valuable if intravenous therapy is

    required for any length of time

    Giving detailed written instructions as to the

    rate of flow, for example, 40 drops/min

    allows one 540 ml unit of blood to be

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    Giving blood

    Site

    As routine measure, vein on the forearm,

    or on the back of the hand is chosen. In

    women, young children, and some men,especially when the venous pressure is

    low, a visible or palpable vein may not be

    found in the arm; consequently anothersite must be used.

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    Monitoring Procedure-

    Two patients with same surname in the same ward

    Both having a blood transfusion

    Patient identification check not undertaken

    Group O patient transfused with Group A RBCs

    Patient complained of generalised pain

    Transfusion continued

    Patient became very ill and died 6 hours later

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    A m ild react ion may be the ear ly stages o f a severe react ion

    - DONT IGNORE IT!

    Signs & Symptoms of aTransfusion ReactionMild Reaction Severe Reaction

    Fever Pyrexia, rigors

    Urticaria HypotensionRash Loin/Back Pain

    Pruritis Increasing anxiety

    Pain at infusion site

    Respiratory Distress

    Dark urineSevere Tachycardia

    Unexpected bleeding (DIC)

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    1. Stopthe transfusion

    (check patient and component compatibility)

    2. Seek medical advice

    3. Assess patient

    4. Commence appropriate treatment

    If s igns & sym ptoms worsen wi th in 15 m inutes

    treat as a severe react io n

    Management of a Mild AcuteTransfusion Reaction

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    1. Stop the transfusion

    Replace the administration setIV access should be maintained with normal saline

    (check patient and component compatibility)

    2. Call the doctor to see the patient urgently

    3. Assess patient - resuscitate as required4. Inform the HTL and return the component

    5. Document event in patient case notes

    Management of a SevereTransfusion Reaction

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    Safer Practice Takes Seconds

    A consistent, professional approach to safe transfusion

    practice can save lives

    Id like to know who I can blame I still feel hate.

    I am furious and angry someone couldnt be bothered

    to treat my chi ld in a pro fessional and safe manner.Mrs Green 15/12/98

    C li ti f bl d

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    Complications of blood

    transfusion

    Congestive cardiac failure

    Transfusion reactions

    IncompatibilitySimple pyrexial reaction

    Allergic reaction

    Antibody reaction

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