Diagnosis of Transfusion Reactions...ABO or other allotypic RBC antigen incompatibility is known OR...

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Diagnosis of Transfusion Reactions The App in your back pocket

Transcript of Diagnosis of Transfusion Reactions...ABO or other allotypic RBC antigen incompatibility is known OR...

Page 1: Diagnosis of Transfusion Reactions...ABO or other allotypic RBC antigen incompatibility is known OR only transfusion-related (i.e., immune or non-immune) cause of acute hemolysis is

Diagnosis of Transfusion ReactionsThe App in your back pocket

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Transfusion Reactions

Blood transfusions are most common procedures for hospitalised patients Adverse effects - 1:70000 per unit Two distinct categories:

– Acute haemolytic transfusion reactions– Delayed haemolytic transfusion reactions

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Transfusion Reactions

Publicly available guidelines for accurate diagnosis Accurate diagnosis is crucial for correct

treatment Guidelines are not user friendly

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Transfusion Rx DDx

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References Pfuntner A, Wier LM, Stocks C 2013. HCUP Statistical Brief #165: Most

Frequent Procedures Performed in U.S. Hospitals, 2011. http://www.hcup-us.ahrq.gov/reports/statbriefs/sb165.pdf. Accessed 15 September 2016

Roback JD, Smith GH 2015. Transfusion Rx DDx [Mobile application software]. Retrieved from http://www.trddx.com.

Sandler SG 2016. Transfusion Reactions. http://emedicine.medscape.com/article/206885-overview. Accessed 15 September 2016

Strobel E 2008. Hemolytic Transfusion Reactions. Transfus Med Hemother 35(5): 346-353.

U.S. Centers for Disease Control and Prevention 2016. The National Healthcare Safety Network (NHSN) Manual: Biovigilance Component v2.2. Available at: http://www.cdc.gov/nhsn/PDFs/Biovigilance/BV-HV-protocol-current.pdf. Accessed 15 September 2016.


Adaptive or Specific Immune Response

Adaptive or Specific Immune Response

Fetal Anaemia and Intrauterine Transfusion 20.2...Fetal Hydrops: • Immune and non-immune Fetal hydrops • Abnormal fluid collection in at least two different fetal compartments:

Fetal Anaemia and Intrauterine Transfusion 20.2...Fetal Hydrops: • Immune and non-immune Fetal hydrops • Abnormal fluid collection in at least two different fetal compartments:

The Immune System. The Immune System in Action When a mosquito bites When you breathe When you have allergies When you get a blood transfusion When you.

The Immune System. The Immune System in Action When a mosquito bites When you breathe When you have allergies When you get a blood transfusion When you.

Clinical Blood Transfusion - moh.gov.sg · 2 Red blood cells transfusion 26 3 Platelet transfusion 44 4 Fresh frozen plasma transfusion 50 5 Cryoprecipitate transfusion 54 6 Safety

Clinical Blood Transfusion - moh.gov.sg · 2 Red blood cells transfusion 26 3 Platelet transfusion 44 4 Fresh frozen plasma transfusion 50 5 Cryoprecipitate transfusion 54 6 Safety

Blood transfusion | Blood transfusion | Guidance | NICE

Blood transfusion | Blood transfusion | Guidance | NICE

BLOOD TRANSFUSION AND TRANSFUSION REACTIONS DR VAISHALI JAIN.

BLOOD TRANSFUSION AND TRANSFUSION REACTIONS DR VAISHALI JAIN.

URTICARIAL TRANSFUSION REACTIONS TRANSFUSION-RELATED ACUTE LUNG INJURY POSTTRANSFUSION PURPURA ANAPHYLACTIC TRANSFUSION REACTIONS DELAYED HEMOLYTIC TRANSFUSION.

URTICARIAL TRANSFUSION REACTIONS TRANSFUSION-RELATED ACUTE LUNG INJURY POSTTRANSFUSION PURPURA ANAPHYLACTIC TRANSFUSION REACTIONS DELAYED HEMOLYTIC TRANSFUSION.

Single Unit Transfusion for Red Blood Cell Transfusion

Single Unit Transfusion for Red Blood Cell Transfusion

National Comparative Audit of Blood Transfusion · preventing the development of HDFN due to immune anti-D. It requires close coordination and cooperation between the transfusion

National Comparative Audit of Blood Transfusion · preventing the development of HDFN due to immune anti-D. It requires close coordination and cooperation between the transfusion

MICROBIOLOGY- ALCAMO LECTURE: IMMUNE DISORDERS. IMMUNE DISORDERS Faulty immune system can either: Over-react or Under-react.

MICROBIOLOGY- ALCAMO LECTURE: IMMUNE DISORDERS. IMMUNE DISORDERS Faulty immune system can either: Over-react or Under-react.

Massive Transfusion Protocol OR Days 0630-2230 M-F

Massive Transfusion Protocol OR Days 0630-2230 M-F

Compatibility Testing Practical Blood Bank. Blood Transfusion Process Pre-transfusion Transfusion Post-transfusion.

Compatibility Testing Practical Blood Bank. Blood Transfusion Process Pre-transfusion Transfusion Post-transfusion.

Hot topics in Paediatric Transfusion and the Emergency ...Transfusion and the Emergency Provision from the Blood Transfusion ... LVT or Standard (100ml) (250 ml) 5-10kg 1 adult unit

Hot topics in Paediatric Transfusion and the Emergency ...Transfusion and the Emergency Provision from the Blood Transfusion ... LVT or Standard (100ml) (250 ml) 5-10kg 1 adult unit

Transfusion Laboratory Manager · Maggi Webb Transfusion Laboratory Manager Northern Devon Healthcare Trust. Anti-D Prophylaxis Back to Basics •History •Immune response •Rh

Transfusion Laboratory Manager · Maggi Webb Transfusion Laboratory Manager Northern Devon Healthcare Trust. Anti-D Prophylaxis Back to Basics •History •Immune response •Rh

Bedside transfusion practice audit - NZBS Transfusion Practice Audit

Bedside transfusion practice audit - NZBS Transfusion Practice Audit

A Compendium of Transfusion Practice Guidelines · therapy, transfusion strategies and alternatives, the transfusion committee, transfusion complications, and infectious disease testing.

A Compendium of Transfusion Practice Guidelines · therapy, transfusion strategies and alternatives, the transfusion committee, transfusion complications, and infectious disease testing.

Administering blood transfusion - CETLcetl.org.uk/learning/print/blood-transfusion-print.pdf · Administering blood transfusion Is it safe? ... Adverse reactions: when to stop a transfusion

Administering blood transfusion - CETLcetl.org.uk/learning/print/blood-transfusion-print.pdf · Administering blood transfusion Is it safe? ... Adverse reactions: when to stop a transfusion

Pre-Transfusion Testing - UCLApathology.ucla.edu/workfiles/Education/Transfusion Medicine/3-4... · Pre-Transfusion Testing ... Risk per Unit Transfusion Transmission Rate Window

Pre-Transfusion Testing - UCLApathology.ucla.edu/workfiles/Education/Transfusion Medicine/3-4... · Pre-Transfusion Testing ... Risk per Unit Transfusion Transmission Rate Window

Massive Transfusion in 30 minutes or less

Massive Transfusion in 30 minutes or less

Guidelines for Home Transfusion · 3. Transfusion 3.1 Pre-Transfusion Sample Collection Pre-transfusion testing is an important step in the delivery of hospital or home transfusions.

Guidelines for Home Transfusion · 3. Transfusion 3.1 Pre-Transfusion Sample Collection Pre-transfusion testing is an important step in the delivery of hospital or home transfusions.