10. Severe Malnutrition

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    Dr. Emmanuel AmeyawDepartment of Child Health

    Kath, Kumasi

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    INTRODUCTION CLASSIFICATION

    SIGNS

    HYPOTHESIS REDUCTIVE ADAPTATION

    MANAGEMENT

    STATISTICS

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    About 20 million children are affected bysevere acute malnutrition globally,

    Leading cause of death in children indeveloping countries,

    contributes to 5060% of all child deaths,

    Mortality rates for children with SAM are 5 to20 times higher compared to well-nourished

    children

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    1 million to 2 million preventable child deathseach year

    Only about 15% get hospital admission

    28% of children under 5 years of age areunderweight.

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    Malnutrition is defined as the failure of cells toperform their physiological functions due toinability receive and use the energy andnutrients needed, (in terms of amounts, mix

    and timeliness).Severe malnutrition is characterized by

    Severe wasting ( weight for height < 70% or

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    Primary malnutrition refers to malnutritionresulting from inadequate food intake

    Secondary malnutrition refers to malnutritionresulting from increased nutrient needs,decreased nutrient absorption, and orincreased nutrient losses.

    Micronutrient malnutrition

    Macronutrient malnutrition

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    Weight for height of

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    Syndromic classification Kwashiokor

    Marasmus

    Marasmic Kwashiokor

    Gomez 1st degree .. .. Wgt between 90% and 75%

    2nd drgree .. .. 75% and 60%

    3rddegree.. Below 60%

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    Wellcome Weight between 80% and 60% (expected weight)

    EdemaKwashiokor

    No edemaundernutrition

    Weight below 60% Edema marasmic kwashiokor

    No edema marasmus

    Jelliffe

    1st degree wgt between 90 and 80% (expected wgt) 2nd degree wgt between 80 and 70% (expected wgt)

    3rd degree wgt between 70 and 60% (expected wgt)

    4th degree below 60% (expected wgt)

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    McLareen Mild: wgt between 90 and 80% (expected)

    Moderate: wgt between 80 and 70% (expected)

    Severe: wgt below 70% (expected)

    Waterloo Acute: wasted but not stunted

    Wgt for height is low, height for age is normal

    Chronic: wasted and stunted

    Wgt for height low, height for age low

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    1. Severe wasting: Loss of fat and muscle (skin and bones)

    Front view: ribs easily seen and skin of upperarm and thighs look loose.

    Back view: ribs and shoulder bones easily seen,flesh missing from the buttocks, folds of skinson buttocks and thighs (wearing baggy pants)

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    2. Oedema of both feet: The retained addedto the weight therefore weight for height > -3SD.

    Rating of oedema:

    + mild: both feet++ moderate: both feet + lower legs + hand

    or lower arms

    +++ severe: generalised (moderate + face)

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    3. Dermatosis Occurs in oedematous malnutrition than wasted

    child.

    Range from patches of abnormal pigmented skin

    (light and dark) to shedding, ulceration andweeping lesion.

    Affects perineum, groin, nappy areas, limbs, behindears, armpit and face

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    4. Eye Signs: Vit. A deficiency

    Night blindness Conjunctivitis xerosis

    Bitot spot Corneal xerosis Cornea ulceration Cornea scar

    Infection Pus

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    In severe malnutrition, the systems almostshut down or slow down in order to allowfor survival on the barest minimum energyrequirements.

    Almost all the major organs are affected

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    HISTORY Frequency of feeding

    Recent appetite

    Usual diet before current illness When last child ate normally

    Breastfeeding history

    Birth history

    Social/Family history

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    MEDICAL HISTORY Vomiting & diarrhea Episodes of fever Chronic cough Birth weight Birth rank and intervals Immunizations Milestones reached before current illness

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    Typical signs of malnutrition Signs of shock

    Signs of infections or heart failure

    Temperature, pulse, and respiratory rate Eye signs,

    Mouth; sore tongue, thrush etc

    Skin lesions

    ENT, Chest Organomegaly, especially the liver, spleen

    Lymph nodes

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    Blood film for Mps Full blood count

    Chest x-ray

    Urine RE & Culture Stool RE & Culture

    VCT-where the suspicion is there

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    Weight for height of

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    Prevent or Treat Hypoglycemia Prevent or Treat Hypothermia Prevent or Treat Dehydration Correct Electrolyte Imbalance

    Treat and Prevent Infections Correct Micronutrient deficiencies Start Cautious feeding Give Catch-up diet Provide TLC and play and stimulation Prepare for Follow-up and discharge

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    Phases Initial phase

    Stabilization phase(1-2)

    Transition phase (3-7)

    Rehabilitation phase(2-6wks)

    Follow ups (7-26 wks)

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    MINERALS Potassium 2340mg

    Magnesium 146mg

    Zinc 40mg Copper 5.6g

    Iodine 154mcg

    Selenium 94mcg

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    Vitamin A 3000mcg Vitamin D 60mcg

    Vitamin E 44mg

    Vitamin C 200mg Vitamin B1 1.4mg

    Vitamin B2 4mg

    Vitamin B6 1.4mg

    Vitamin B12 2mcg

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    Vitamin K 80mcg Biotin 0.2mg

    Folic acid 700mg

    Patothenic acid 6mg Niacin 20mg

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    F 75 F 100

    Suji

    RUTF

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    Treat infections and other medical problems Provide sufficient energy and nutrients to

    stop further loss of muscle and fat

    Revive the cells and organs that are almostdormant

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    Provide extra energy and nutrients for rapidweight gain

    Start stimulating the child to improve mentaland motor development

    Start educating carer on how to continuecaring for the child after discharge

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    Starter formula (F 75 here) Must contain milk, sugar and oil

    Must be low in sodium and protein and highin sugar

    Must be fed in small amounts every 3 hoursday and night. Feed very ill children 2hrly.

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    Feed by NGT if a child; Is lethargic and refuses to eat

    Has refused or vomited the last 2 consecutivefeeds

    Is taking

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    Child is active and smiling Edema resolving or resolved

    Increased appetite

    Continue with F 100 or RUTF

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    Catch-up diets are high in energy and proteinand some micronutrients

    It contains more milk and oil and less sugarthan starter formula

    Rapid weight gain Give high energy snacks such as bread and

    margarine, banana between feeds

    Avoid salty foods

    Weight gain should be aimed at 10g/kg/day

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    In severe malnutrition, theres delayedbehavioral and mental development.

    These can be improved by giving;

    TLC

    A cheerful stimulating environment

    Structured play therapy,15-30min/day

    Physical activities as soon as well enough

    Maternal involvement as much as possible

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    Counselling Bringing child back for regular follow-up

    checks

    Ensure they complete immunizationschedules

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    HYPOGLYCAEMIA Blood sugar

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    When axillary temperature

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    Difficult to rely on usual signs to tell severity

    of dehydration

    Assume all children with watery diarrhea may

    have some dehydration No IV fluids except in shock

    ReSoMal-ideal solution in malnutrition; giveorally or by NGT.

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    ReSoMal: 5ml/kg every 30mins for the 1st 2hours, then 5-10ml/kg/hr for the next 4-10hours

    Start starter feeds after 4 hours

    Continue breastfeeding

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    Look out for signs of over hydration Puffy face

    Engorged jugular vein

    Pulse

    Respiratory rate

    HR

    Crackles

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    Assume all malnourished children have aninfection

    Hypoglycemia & hypothermia are signs ofsevere infections

    Give broad-spectrum antibiotics Keep warm Check RTHC for at least measles vaccine,

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    All severely malnourished children have vitamin& mineral deficiencies

    Do not give iron within the first 2 weeks Give;

    Vitamin A Multivitamin supplement

    Folic acid Zinc

    Copper

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    Haemotransfusion required if Hb

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    Common causes Misdiagnosis of dehydration with consequent

    inappropriate hydration

    Very severe anemia

    Overloading due to blood transfusion High Na diet using conventional ORS or

    excess ReSoMal

    Inappropriate treatment of refeeding

    diarrhea with rehydration solutions

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    First fast breathing 2-12 months: RR>50 cpm

    1-5years: RR>40cpm

    Later

    Cyanosis or pulse oximetry,SaO2 2cm

    Engorged jugular veins

    Increased pulse rate

    Lung crepitations

    Respiratory distress

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    Stop all oral intake and IV fluid No fluid should be given until cardiac

    function improves

    A diuretic-IV lasix,1mg/kg stat

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    TB can be a cause of failure to gain weight Signs are often non-specific

    Asymmetric chest signs or lymph nodes areusually TB

    The mantoux test can be negative Take a chest x-ray

    To treat as soon as the suspicion is there

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    Nutritional treatment of HIV/HIV-suspectedpatients is the same as for any severelymalnourished patient

    They require the same dietary and medical

    treatment HIV-positive patients usually respond well to

    the nutritional treatment and gain weight

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    Children can be allowed to go home if they; Have completed the transition to catch-up diets and are

    eating well

    Have no edema

    Have completed antibiotic treatment

    Have received extra electrolytes and micronutrients for atleast 2 weeks

    Have been gaining weight well for at least 1week

    Are up to date with their immunizations

    W-f-h of >85%,if theres good follow-up services; w-f-h

    of >95% without good follow-up services

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    MONTH KWASHIOKOR MARASMUS MK TOTAL FATALITY

    January 7 15 2 24 2

    February 0 15 2 17 3

    March 1 13 1 15 4

    April 1 20 3 24 0

    May 5 20 4 29 5

    June 2 18 3 23 1

    July 0 15 4 19 4

    August 3 16 3 22 4

    September 4 12 0 16 2

    October 1 14 3 18 3

    November 10 20 8 38 9

    December 10 17 4 31 2

    TOTAL 44 195 37 276 39

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    MONTH KWASHIOKOR MARASMUS MK TOTAL FATALITY

    January 2 24 4 30 1

    February 3 35 6 44 3

    March 5 30 1 37 6

    April 9 24 1 34 4

    May 1 17 0 18 3

    June 3 15 2 20 5

    July 4 19 2 25 1

    TOTAL 27 164 16 207 23

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    14.13% for 2008 11.11% for 2009

    Both primary and secondary

    WHO accepts between 5-10%

    Resources available: 1-5%

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    Part of Ward B4 Four nutritionist

    3 pediatricians

    1 resident

    3/4 house officers

    Nurses

    Health care assistants

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    Over crowding Nocturnal feedings

    No office and store for feeds

    Funds for alternate feeds

    Hospital bill

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    Case management practices suitable for the

    non malnourished child may be highlydangerous for the PEM child

    A malnourished child can be likened to apremature neonate

    Very delicate and fragile, but when given thenecessary care and treatment, can surpriseeven you

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