026.aggressive periodontitis

13
Dr Jaffar Raza Syed Page 1 Aggressive Periodontitis “characterized by the rapid loss of attachment and bone loss occurring in an otherwise clinically healthy patient with the amount of microbial deposits inconsistent with disease severity and familial aggregation of diseased individuals formerly classified as early onset periodontitis” localized juvenile periodontitis (LJP) has been changed to localized aggressive periodontitis (LAP) generalized aggressive periodontitis was previously classified as generalized juvenile periodontitis (GJP) and rapidly progressive periodontitis (RPP).

Transcript of 026.aggressive periodontitis

Page 1: 026.aggressive periodontitis

Dr Jaffar Raza Syed Page 1

Aggressive Periodontitis “characterized by the rapid loss of attachment and bone loss occurring in an otherwise

clinically healthy patient with the amount of microbial deposits inconsistent with

disease severity and familial aggregation of diseased individuals formerly classified as

early onset periodontitis”

localized juvenile periodontitis (LJP) has been changed to localized aggressive

periodontitis (LAP)

generalized aggressive periodontitis was previously classified as generalized juvenile

periodontitis (GJP) and rapidly progressive periodontitis (RPP).

Page 2: 026.aggressive periodontitis

Dr Jaffar Raza Syed Page 2

Clinical Features of LAP: Age and Sex Distribution

between puberty and 20 years of age

both sexes but predilection to female patients. Distribution of Lesions Three areas of localization of bone loss have been described:

1. First molar and/or incisors.

2. First molar and/or incisors + additional teeth (not exceeding 14 teeth).

3. Generalized involvement

Page 3: 026.aggressive periodontitis

Dr Jaffar Raza Syed Page 3

Clinical Findings

most striking feature is lack of clinical inflammation despite the presence of deep periodontal pockets

mobility and migration of first molars and incisors

other symptoms like root surface sensitivity, deep dull radiating pain, periodontal abscess formation and regional lymph node enlargement may occur Radiographic Findings

Arc-shaped loss of alveolar bone extending from distal surface of 2nd premolar to mesial surface of 2nd molar.

Frequently, bilaterally symmetrical patterns of bone loss occurs, called as “mirror image pattern”

Page 4: 026.aggressive periodontitis

Dr Jaffar Raza Syed

Page 4

Page 5: 026.aggressive periodontitis

Dr Jaffar Raza Syed

Page 5

Page 6: 026.aggressive periodontitis

Dr Jaffar Raza Syed Page 6

Pathogenesis

Specific microbiology of subgingival plaque,

A. actinomycetemcomitans,

Capnocytophaga sputigena

others

defects in cementum,

hereditary factors,

impaired PMNs function

disorders of the immune system.

Page 7: 026.aggressive periodontitis

Dr Jaffar Raza Syed

Virulence factors associated with

associated with A. actinomycetemcomitans are

Page 7

Page 8: 026.aggressive periodontitis

Dr Jaffar Raza Syed Page 8

Treatment

Extraction of involved teeth

Transplantation of developing third molars into the sockets of previously extracted 1st molars

Standard periodontal therapy: Includes

scaling, root planing,

curettage,

flap surgery with/without bone grafts,

root amputation,

hemisection,

occlusal adjustment and strict plaque control has been tried

Page 9: 026.aggressive periodontitis

Dr Jaffar Raza Syed Page 9

Antibiotic therapy

scaling and root planing and tetracycline 250 mg qid for 14 days every 8 weeks.

excellent bone fill noted in cases of LAP treated with tetracycline, flap surgery and placement of grafts

Doxycycline 100 mg/day may also be used.

Chlorhexidine rinses should be prescribed.

In refractory cases,

tetracycline resistant Actinobacillus species have been suspected. In such cases, a combination of amoxicillin and metronidazole has

Been suggested

Page 10: 026.aggressive periodontitis

Dr Jaffar Raza Syed Page 10

GENERALIZED AGGRESSIVE PERIODONTITIS “characterized by generalized interproximal attachment loss affecting atleast three permanent teeth other than first molars and incisors” most pathogenic organisms may be associated, e.g.

Porphyromonas gingivalis,

A. actinomycetemcomitans,

Bacteroids forsythus

Page 11: 026.aggressive periodontitis

Dr Jaffar Raza Syed Page 11

Clinical Characteristics Age and sex distribution:

It affects persons between puberty and 35 years (but may be older).

No sex discrimination is seen. Distribution of lesion:

No specific pattern is observed,

all or most of the teeth are affected.

Some of the patients may have systemic manifestations such as

weight loss,

mental depression and

general malaise.

Page 12: 026.aggressive periodontitis

Dr Jaffar Raza Syed

Page 12

Page 13: 026.aggressive periodontitis

Dr Jaffar Raza Syed Page 13

Treatment of Aggressive Periodontitis

full mouth disinfection which has been proposed by Quirynen et al. Since it was observed that A. a has the ability to translocate from one person to another and from site to site, full mouth disinfection was implemented.

It includes the following steps:

Full mouth scaling and root planing (in 2 sessions within 24 hours).

Brushing the dorsum of the tongue with an antimicrobial agent (1% chlorhexidine gel) for one minute.

Mouthrinsing with antimicrobial agents.

Home irrigation systems. Other Treatment Options • Local drug delivery system. • Host modulation therapy