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سطام األمير جامعة المساعد الصيدلية الكيمياء أستاذالسعودية - العربية المملكة الخرج عبدالعزيز بن

ا"ل"ذ"ا"ت"ي"ة" ا"ل"س"ي"ر"ة"لتميمي/ ا الفواز صالح بن عبدالملك الدكتور

Name: ABDULMALIK SALEH M ALTAMIMIAssistant professor and head of pharmaceutical chemistry department, college of pharmacy Prince Sattam bin Abdulaziz University, Alkharj, Saudi Arabia

Personal Data Scientific Backgroun d Professional Position s Administrative position s Prize s Trainin g Publication s

Supervision of Master & Ph.D. Thesi s List of Publication s L a n g u a g e s

Personal Data

Position: ASS. Prof of Pharmaceutical Chemistry Date and Place of Birth: 9/1/1970, Riyadh.Present Address: Riyadh, Saudi ArabiaWork Phone: 00966-11-5886072Home Phone: 00966-11-7210000Mobile Phone: 00966-543888833Fax: 00966-11-5886001E-mail: [email protected]

Scientific Background

1433: Ph.D. Pharmaceutical Sciences [Pharmaceutical Chemistry], King Saud University, Riyadh, Saudi Arabia.

1422: M.Sc. Pharmaceutical Sciences [Pharmacology], King Saud University, Riyadh, Saudi Arabia.

1415: B.Sc. Pharmaceutical Sciences, King Saud University, Riyadh, Saudi Arabia.

Professional Positions

Chairman of Pharmaceutical Chemistry Department, College of Pharmacy, Prince Sattam bin Abdulaziz University since 16-11-1437.

Vice Dean of Scientific Research 1-6-1435 – 30-5-1437 Chairman of Pharmaceutical Chemistry Department, College of Pharmacy,

Prince Sattam bin Abdulaziz University 18-10-1434 -30-5-1435. Assistant Professor of Pharmaceutical Chemistry [Medicinal Chemistry], Prince

Sattam bin Abdulaziz University, Al-Kharj since 1-4-1434.

التميمي/ | 1 عبدالملك │ د P S A U

1415-1432: A lot of administrative positions at the Ministry of Health.

اللجان عضوية

من .1 الصيدلة بكلية العلمي البحث وأخالقيات استراتيجيات لجنة رئيس3/12/1437. تاريخه حتى هـ

من .2 الصيدلة بكلية التميز بدل لجنة .3/12/1437رئيس تاريخه حتى هـمن .3 الميداني الصيدلي التدريب على االشراف لجنة في عضواً

3/12/1437. تاريخه حتى هـتاريخ .4 من الصيدلية الكيمياء قسم تاريخه 1437-11-16رئيس حتىتاريخ .5 من العلمي البحث عمادة حتى 1/6/1435وكيل .30/5/1437هـتاريخ .6 من العلمي البجث عمادة مجلس حتى 1/6/1435أمين .30/5/1437هـبتاريخ .7 الحيوية البحوث أخالقيات لجنه .25/12/1435رئيس تاريخه حتى هبتاريخ .8 والتحقيق والترجمة التأليف لجنة تاريخ 23/7/1436رئيس حتى ه

30/5/1437.تاريخ .9 من التدريس هيئة ألعضاء والبدالت للحوافز الدائمة اللجنة ً عضوا

الى 15/5/1435 ه .8/11/1436همن .10 التدريس هيئة اعضاء من الكليات حاجة لتقييم الدائمة اللجنة عضو

.1435-11-15الى 15-5-1435العربية .11 مصر جمهورية من التعاقد لجنة .1435-8-28الى 1435-8-20عضوآفاق ) .12 مشروع الجامعي للتعليم المستقبلية الخطة مقترحات لجنة مقرر

ه .7/7/1435بتاريخ( بتاريخ .13 الميداني الصيدلي التدريب على اإلشراف لجنة هـ8/7/1435عضواً

هـ .7/7/1437حتى الصحية ..14 للعلوم بالجامعة البحثية األولويات تحديد فريق رئيسالتدريس .15 هيئة ألعضاء البحثي للتميز التشجيعية للمكافآت لجنة عضواً

بتاريخ السعوديين ه .19/3/1436لغيربن .16 سطام االمير جامعة بين التعاون اتفاقية تطبيق عمل فريق عضواً

بتاريخ المخدرات لمكافحة العامة والمديرية ه .5/7/1435عبدالعزيز

Conferences

5th Ubiquitin Research and Drug Discovery Conference held by Global Technology community “GTC bio” in San Diego CA, USA during February 26-27, 2015.

, " التحديات التمويل العلمي البحث لدعم األول السعودي الؤتمرللعلوم" عبدالعزيز الملك مدينة في الرياض بمدينة المنعقد والحلول

بتاريخ م2014نوفمبر 4-2والتقنية MEETING: Drug Discovery Chemistry, organized by Cambridge Healthtech

Institute, in San Diego CA, USA during April 23-25, 2014. The Fourth Annual International Conference of MEDCHEM-2013, held in

Hainan, China during November 13-16, 2013. 5th International Symposium on Advances in Synthetic and Medicinal Chemistry

held in Moscow, Russia during May 5-8, 2013.


Fifth international conference on Medicinal Chemistry at Beijing China; held during May 10-15, 2012.

7th International Saudi Pharmaceutical Conference 2009. 5th International Saudi Pharmaceutical Conference 2007.

Workshops and Trainings

الحيوية البحوث ألخالقيات المحلية اللجان ألعضاء الثالث 7الملتقى والتقنيةز 2016يناير للعلوم عبدالعزيز الملك مدينة في انعقد والذي

THE TRAINING COURSES FOR MEMEBERS OF LOCAL COMMITTEES OF RESEARCH ETHICS” organized by National Committee of Bioethics and King Saud University, Riyadh, KSA on November 19, 2015.

“RESEARCH COOPERATION AMONG UNIVERSITIES AND PRIVATE SECTOR in SCIENTIFIC RESEARCH” organized by King Saud University Deanship of scientific research, Riyadh, KSA during October 28-29, 2015.

“FUNDING, CHALLENGES AND SOLUTIONS” organized by KAUST in Riyadh, KSA during November 2-4, 2014.

Methods assessments of learning outcomes during February 12/2014 organized by Salman bin Abdulaziz University, Alkharj, KSA.

“SAUDI DIGITAL LIBRRAY TRAINING ON USING DIGITAL DATABASES” organized by SDL and Ministry of Higher Education KSA on October 9, 2013.

“ACADEMIC ADVISING” organized by Salman bin Abdulaziz University, Alkharj, KSA, on March 11, 2013.

“LEADERSHIP IN STUDENTS AFFAIRS” organized by Ministry of Higher Education, KSA, during March 04-05, 2013.

"STRATEGIC PLANNING AND EFFECTIVE LEADERSHIP" Sponsored by Strategic Planning Project team, King Saud University, Riyadh, KSA, held on June, 28/ 2008.

"CHINESE EXPERIENCE IN NANO INDUSTRY" Sponsored by King Abdullah Institute for Nanotechnology, King Saud University, Riyadh, Saudi Arabia, held during MAY 25-27/2008.

"ACTIVE LEARNING AND TEACHING LARGE CLASSES” by Dr. Sergio Piccinin. This was sponsored by Deanship of Skills Development, King Saud University, Riyadh, Saudi Arabia and held on April 26/ 2008 for 6 Training Hours.

“PARAMETRIC AND NON-PARAMETRIC TESTS USING SPSS” held during February 23-27/2008 and Sponsored by Deanship of Skills Development, King Saud University Riyadh, KSA.

“PREPARING DATA USING SPSS”. Sponsored by Deanship of Skills Development, King Saud University Riyadh, KSA, during February 16-20/2008.

NANO RESEARCH AT UNIVERSITIES: the Road towards fulfilling the Vision of the Custodian of the Two Holly Mosques” 1st Workshop; King Saud University, Riyadh, Saudi Arabia, held on October 29/ 2007.

الدورات


- " التحليل في وتطبيقات اساسيات التتدريبي البرنامج تدريس اقامة " من فترة في المنعقد للمخدرات والكمي الكيفي للتعيين -12-6اآللي

سطام 2016-1-4الى 2015 االمير جامعة الصيدلة كلية في اقيم والذي الخرج في عبدالعزيز .بن

Research Grants

Summer Research Grant for New Saudi Staff Members during summer, June 10 th

to September 1st 2013, with Professor Claudiu T. Supuran at University Delgi Studi, Florence, Italy.Research grant from King Abdulazz City for science and technology (KACST) 2015.In addition some projects sponcered by deanship of scientific research, prince Sattam Bin Abdulaziz University between years 2014-2016.

List of Publications

1. Abdul-Malek S. Al-Tamimi, Electronic structure, hydrogen bonding and

spectroscopic profile of a new 1,2,4-triazole-5(4H)-thione derivative: A combined

experimental and theoretical (DFT) analysis, Journal of Molecular Structure 1120

(2016) 215e227.

2. Murat Bozdag , Ahmed M. Alafeefy , Fabrizio Carta , Mariangela Ceruso , Abdul-

Malek S. Al-Tamimi ,Abdulla A. Al-Kahtani , Fatmah A. S. Alasmary , Claudiu T.

Supuran , Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-

benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory

properties, Bioorganic & Medicinal Chemistry 24 (2016) 4100–4107.

3. Ahmed M. Alafeefy , Fabrizio Carta , Mariangela Ceruso , Abdul-Malek S. Al-

Tamimi ,Abdulla A. Al-Kahtani , Claudiu T. Supuran, Development of 3-(4-

aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of

carbonic anhydrase isoforms involved in tumorigenesis and glaucoma, Bioorganic

& Medicinal Chemistry 24 (2016) 1402–1407.

4. Monirah A. Al-Alshaikh, Hazem A. Ghabbour*, Abdul-Malek S. Al-Tamimi,

Mohammed S.M. Abdelbaky, Santiago Garcia-Granda and Ali A. El-Emam, Crystal


structure of 5-(adamantan-1-yl)-3-[(4-chloroanilino)methyl]-2,3-dihydro-1,3,4-

oxadiazole-2-thione, C19H22ClN3OS, Z. Kristallogr. NCS 2016;v 231, p301-303.

5. Ahmed M. Alafeefy , Rehan Ahmad , Maha Abdulla , Wagdy M. Eldehna ,Abdul-

Malek S. Al-Tamimi , Hatem A. Abdel-Aziz , Omar Al-Obaid , Fabrizio

Carta ,Abdulla A. Al-Kahtani , Claudiu T. Supuran , Development of certain new 2-

substituted-quinazolin-4-ylaminobenzenesulfonamide as potential antitumor

agents, European Journal of Medicinal Chemistry 109 (2016) 247e253.

6. Ebtehal S. Al-Abdullah, Hazem A. Ghabbour, Hamad M. Alkahtani, Abdul-Malek S.

Al-Tamimi and Ali A. El-Emam, Crystal structure of N-(adamantan-1-yl)-4-

phenylpiperazine-1-carbothioamide, C21H29N3S, Z. Kristallogr. NCS 2016; aop.

7. Haya I. Aljohar, Hazem A. Ghabbour*, Abdul-Malek S. Al-Tamimi, Haitham

AlRabiah and Ali A. El-Emam, Crystal structure of 4-[(E)-(2-chloro-6-

fluorobenzylidene)amino] -1,2-dihydro-2,3-dimethyl-1-phenylpyrazol-5-one,

C18H15ClFN3O, Z. Kristallogr. NCS 2016; aop.

8. Abdul-Malek S. Al-Tamimi, Hazem A. Ghabbour* and Ali A. El-Emam, Crystal

structure of N'-(adamantan-2-ylidene)pyridine-3-carbohydrazide, C16H19N3O, Z.

Kristallogr. NCS 2016; 231(2): 573–575.

9. Abdul-Malek S. Al-Tamimi, Hazem A. Ghabbour* and Ali A. El-Emam, Crystal

structure of 6-oxo-4-propyl-2-(propylthio)-1,6-dihydropyrimidine-5-carbonitrile,

C11H15N3OS, Z. Kristallogr. NCS 2016; 231(2): 583–585.

10. Murat Bozdag , Ahmed M. Alafeefy , Daniela Vullo , Fabrizio Carta , Nurcan

Dedeoglu ,Abdul-Malek S. Al-Tamimi , Nabila A. Al-Jaber , Andrea Scozzafava ,

Claudiu T. Supuran , Benzenesulfonamides incorporating bulky

aromatic/heterocyclic tails with potent carbonic anhydrase inhibitory activity,

Bioorganic & Medicinal Chemistry 23 (2015) 7751–7764.

11. Alafeefy AM, Ceruso, M, Al-Tamimi AM, Del Prete S, Supuran CT, Capasso C.

Inhibition studies of quinazoline-sulfonamide derivatives against the gamma-CA

(PgiCA) from the pathogenic bacterium, Porphyromonas gingivalis. JOURNAL OF

ENZYME INHIBITION AND MEDICINAL CHEMISTRY. AUG 2015; 30(4): 592-596.

12. Alafeefy AM, Abdel-Aziz HA, Vullo D, Al-Tamimi AM, Awaad AS, Mohamed MA,

Capasso C, Supuran CT. Inhibition of human carbonic anhydrase isozymes I, II, IX

and XII with a new series of sulfonamides incorporating aroylhydrazone-,

[1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-


thiadiazol-3(2H)-yl moieties. JOURNAL OF ENZYME INHIBITION AND MEDICINAL

CHEMISTRY. FEB 2015; 30(1): 52-56.

13. Sebastian SSHR, Al-Tamimi AM, El-Brollosy NR, El-Emam AA, Panicker, CY, Van

Alsenoy C. Vibrational spectroscopic (FT-IR and FT-Raman) studies, HOMO-

LUMO, NBO analysis and MEP of 6-methyl-1-({[(2E)-2-methyl-3-phenyl-prop-2-

en-l-yl]oxy}methyl)-1,2,3,4-tetra-hydroquinazoline-2,4-dione, a potential

chemotherapeutic agent, using density functional methods. SPECTROCHIMICA

ACTA PART A. JAN 5 2015; 134: 316-325.

14. Mary YS, Al-Tamimi AM, El-Brollosy NR, El-Emam AA, Jojo PJ, Panicker CY, Van

Alsenoy C. Molecular structure and vibrational spectra of 2-Ethoxymethyl-6-

ethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione, a potential chemotherapeutic

agent, by density functional methods. SPECTROCHIMICA ACTA PART A. DEC 10

2014; 133: 439-448.

15. Alafeefy AM, Ceruso M, Al-Tamimi AM, Del Prete S, Capasso C, Supuran CT.

Quinazoline-sulfonamides with potent inhibitory activity against the alpha-

carbonic anhydrase from Vibrio cholera. BIOORGANIC & MEDICINAL

CHEMISTRY. OCT 1 2014; 22: 5133-5140.

16. Sert Y, El-Emam AA, Al-Abdullah ES, Al-Tamimi AM, Cirak C, Ucun F. Use of

vibrational spectroscopy to study 4-benzyl-3-(thiophen-2-yl)-4,5-dihydro-1H-

1,2,4-triazole-5-thione: A combined theoretical and experimental approach.

SPECTROCHIMICA ACTA PART A. MAY 21 2014; 126: 280-290.

17. Al-Tamimi AM, El-Emam AA, Al-Deeb OA, Prasad O, Pathak SK, Srivastava R,

Sinha L. Structural and spectroscopic characterization of a novel potential anti-

inflammatory agent 3-(adamantan-1-yl)-4-ethyl-1H-1,2,4-triazole-5(4H)thione

by first principle calculations. SPECTROCHIMICA ACTA PART A. APR 24 2014;

124: 108-123.

18. Alafeefy AM, Abdel-Aziz HA, Vullo D, Al-Tamimi AM, Al-Jaber NA, Capasso C,

Supuran CT. Inhibition of carbonic anhydrases from the extremophilic bacteria

Sulfuri hydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a

new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b]

[1,3,4]thiadiazinyl-or2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl

moieties. Bioorganic Med Chem. 2014 Jan 1; 22(1):141-7.


19. Abdul-Malek S. Al-Tamimi , Ahmed M. Alafeefy, Ali A. El-Emam, Seik Weng Ng

and Edward R. T. Tiekink. 5-(Adamantan-1-yl)-N-methyl-1,3,4-thiadiazol-2-

amine. Acta Crystallographica Section E. Online April 2013.

20. El-Emam AA, Al-Tamimi AM, Al-Omar MA, Alrashood KA, Habib EE. Synthesis and

antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-

1,2,4-triazoline-3-thiones. Eur J Med Chem. 2013;68C:96-102.

21. Abdul-Malek S. Al-Tamimi, Ebtehal S. Al-Abdullah, Ali A. El-Emam, Seik Weng Ng

and Edward R. T. Tiekink. 3-(Adamantan-1-yl)-4-[(E)-(2,6-difluorobenzylidene)

amino]-1-[(4-ethylpiperazin-1-yl)methyl]-4,5—dihydro-1H-1,2,4-triazole-5-thione.

Acta Crystallographica Section E. Online April 2013.

22. Abdul-Malek S. Al-Tamimi , Ahmed M. Alafeefy, Ali A. El-Emam, Seik Weng Ng

and Edward R. T. Tiekink. 5-(Adamantan-1-yl)-3-[(4-fluoroanilino)methyl]-2,3—

dihydro-1,3,4-oxadiazole-2-thione. Acta Crystallographica. E69, o730, Online April

2013.

23. Abdul-Malek S. Al-Tamimi, Omar A. Al-Deeb, Ali A. El-Emam, Seik Weng Ng and

Edward R. T. Tiekink. 5-(Adamantan-1-yl)-3-anilinomethyl]-2,3—dihydro-1,3,4-

oxadiazole-2-thione. Acta Crystallographica. E69, o729, Online April 2013.

24. Ali A. El-Emam, Abdul-Malek S. Al-Tamimi, Khalid A.Alrashood, Seik Weng Ng . and Edward R. T. Tiekink. 3-(Adamantan-1-yl)-4-methyl-1-({4-[3-

(trifluoromethyl)phenyl]piperazin-1-yl}-methyl)-4,5-dihydro-1H-1,2,4-triazole-5-

thione. Acta Crystallographica ,E69, o695–o696, Online April 2013.

25. Abdul-Malek S. Al-Tamimi, Ebtehal S. Al-Abdullah,Ali A. El-Emam, Seik Weng Ng

and Edward R. T.Tiekink, 3-(Adamantan-1-yl)-4-[(E)-(2,6-

difluorobenzylidene)amino]-1-[(4-ethylpiperazin-1-yl)methyl]-4,5-dihydro-1H-

1,2,4-triazole-5-thione, Acta Crystallographica , E69, o685–o686, Online April

2013.

26. Ali A. El-Emam, Abdul-Malek S. Al-Tamimi, Khalid A. Al-Rashood, Hriday N. Misra,

Vijay Narayan, Onkar Prasad, Leena Sinha. Structural and spectroscopic

characterization of a novel potential chemotherapeutic agent 3-(1-adamantyl)-1-

{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-4-methyl-1H-1,2,4-triazole-5(4H)-

thione by first principle calculations. Journal of Molecular Structure, Volume

1022, 29 August 2012, Pages 49-60.

27. El-Emam AA, Al-Omar MA, Al-Tamimi AM, Ng SW, Tiekink ER. 3-(Adamantan-1-

yl)-1-[(4-benzyl-piperazin-1-yl)meth-yl]-4-[(E)-(2-hy-droxy-benzyl-idene)amino]-


1H-1,2,4-triazole-5(4H)-thione. Acta Crystallogr Sect E Struct Rep Online. 2012 Jun

1;68(Pt 6):o1766-7. doi: 10.1107/S1600536812021204.

28. El-Emam AA, Alrashood KA, Al-Omar MA, Al-Tamimi AM. Synthesis and

antimicrobial activity of N'-heteroarylidene-1-adamantylcarbohydrazides and (±)-

2-(1-adamantyl)-4-acetyl-5-[5-(4-substitutedphenyl-3-isoxazolyl)]-1,3,4-

oxadiazolines. Molecules. 2012 Mar 16;17(3):3475-83. doi:

10.3390/molecules17033475.

29. El-Emam AA, Alrashood KA, Al-Tamimi AM, Ng SW, Tiekink ER. 3-(Adamantan-1-

yl)-1-[(4-ethyl-piperazin-1-yl)meth-yl]-4-[(E)-(4-hy-droxy-benzyl-idene)amino]-1H-

1,2,4-triazole-5(4H)-thione. Acta Crystallogr Sect E Struct Rep Online. 2012 Mar

1;68(Pt 3):o657-8. doi: 10.1107/S1600536812005107.

30. El-Emam AA, Al-Omar MA, Al-Tamimi AM, Ng SW, Tiekink ER. 3-(Adamantan-1-

yl)-4-methyl-1-[(4-phenyl-piperazin-1-yl)meth-yl]-1H-1,2,4-triazole-5(4H)-thione

dichloro-methane hemisolvate. Acta Crystallogr Sect E Struct Rep Online. 2012

Jun 1;68(Pt 6):o1772-3. doi: 10.1107/S1600536812021393.

31. Al-Tamimi AM, Bari A, Al-Omar MA, El-Emam AA, Ng SW. N'-[(2-n-Butyl-4-chloro-

1H-imidazol-5-yl)-methyl-idene]adamantane-1-carbo-hydrazide sesquihydrate

ethanol hemi-solvate. Acta Crystallogr Sect E Struct Rep Online. 2010 Jul 31;66(Pt

8):o2131. doi: 10.1107/S1600536810029260.

32. Al-Tamimi AM, Bari A, Al-Omar MA, Alrashood KA, El-Emam AA. 3-(1-Adamant-

yl)-1-{[4-(2-meth-oxy-phen-yl)piperazin-1-yl]meth-yl}-4-methyl-1H-1,2,4-triazole-

5(4H)-thione. Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 23;66(Pt

7):o1756. doi: 10.1107/S1600536810022695.

Languages

Arabic: Native speaker. English: Passed the English language program, offered by The Institute of Public

Administration, for candidates for studies abroad with overall “Excellent” grade. French: Fair.


http://www.ncbi.nlm.nih.gov/pubmed/22719551



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