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MATERIAL SAFETY DATA SHEETDoc #: EHSIFI027 Ref SOP #: EHS/SOP/024

Product Name: Acetyl ChlorideEffective Date: 10.05.2016Rev. #: 00

SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATIONProduct Name Acetyl Chloride

Chemical Formula CH3COCI Chemical Name I Acetyl Chloride

Synonyms Acetic Acid Chloride; Ethanoyal Chloride.

IOL Chemicals and Pharmaceuticals LimitedViII. - Fatehgarh Channa, Mansa Road, Trident Complex, Barnala - 148101

Company (Punjab) IndiaIdentification Tel No.: +91-1679-285285-86

Fax No.: +91-1679-285292Email: [email protected]

SECTION 2 - COMPOSITION I INFORMATION ON INGREDIENTS

Hazardous LDsoof IngredientsIngredients Acetyl Chloride (specify species & route of Not available(specific) administration)

% (by weight) >98%LCso of Ingredients

LC50: Not available(specify species)

CAS Number 75-36-5 ECNo. 200-865-6

SECTION 3 - HAZARDS IDENTIFICATIONRoute ofEntry

Tissue damage,ulceration,permanent

Severeirritation or Choking,bums to the coughing,

headache,eyes with tightness in chest,possible shortness of

permanent. Ihu'!OIthdamage andblindness.

Severe bums to

Skin Contact SkinAbsorption

scarring.

EyeContact Inhalation Ingestion

I.....P"PTP bums,tissue damage,

Symptoms ulceration,permanentscarrmg.

mouth, throat,'~"'''_'''' with

nauseavomiting.

destruction,abdominal pain,

vomiting of blood;

Class 3 Indication of Danger: Highly Flammable. Corrosive.r---------------------+Health Class

[WHMIS Symbols] 4WE,flammable liquid, corrosive, which reacts

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MATERIAL SAFETY DATA SHEETDoc #: EHS/F/027 Ref SOP #: EHS/SOP/024

SECTION 4 - FIRST AID MEASURES

Skin Contact Wash with soap and water. Cover the irritated skin with an emollient. Getmedical attention if irritation develops. Cold water may be used.

Serious Skin Contact Get medical attention immediately.

Eye Contact Immediately flush eyes with plenty of water for at least 15minutes, liftingupper and lower eyelids occasionally.

Serious Eye Contact Get medical attention immediately.

Inhalation Remove to fresh air.

Evacuate the victim to a safe area as soon as possible. Loosen tight

Serious Inhalation clothing such as a collar, tie, belt or waistband. If breathing is difficult,administer oxygen. If the victim is not breathing, perform mouth-to-mouthresuscitation. Get medical attention immediately.

Do not induce vomiting unless directed to do so by medical personnel.Ingestion Never give anything by mouth to an unconscious person. Loosen tight

clothing such as a collar, tie, belt or waistband.

Serious Ingestion Never give anything by mouth to an unconscious person. Get medicalattention immediately.

SECTION 5 - FIRE FIGHTING MEASURES

Flammable: ~ Yes Extremely flammable liquid and vapour, maycause flash fire.Use dry chemical powder, sand etc.Protective Equipment: Wear self-containedbreathing apparatus and protective clothing to

Means of Extinction & Instruction prevent contact with skin and eyes.Specific Hazard(s): Flammable liquid, emitstoxic fumes under fire conditions. Vapour maytravel considerable distance to source of ignitionand flash back.

Fire Class B/3 Severe

Flash Point

Open Cup Not availableUEL (% by 19% LEL(% by 7.3 %volume) volume)

Close Cup 4°C

Explosion Liquid/vapour andAuto Explosion Data None Data- air mixture in theIgnition 390°C (734F) Sensitivity To identified Sensitivity to flammable rangeTemperature Contact Static may be ignited by a

Discharge static charge.


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MATERIAL SAFETY DATA SHEET .Doc #: EHS/FI027 Ref SOP #: EHS/SOP/024

Hazardous Combustion Phosgene, Hydrogen Chloride Gas, CO, CO2ProductsFire Hazard in Presence of In presence of open flames and sparks, of heat and incompatibles.

Explosion Hazard Explosive in presence of open flames, sparks and heat.

Remarks on Fire Hazard Keep away the ignition sources.

Remarks on Explosion It can become potentially explosive during distillation orHazard evaporation.

Suitable: Carbon dioxide, Dry chemical power andMAP storedExtinguishing Media pressure type fire extinguishers. Dry sand.

Unsuitable: Do not use water.

SECTION 6 - ACCIDENTAL RELEASE MEASURES:

Small SpilllLeak Mop up, or absorb with an inert dry material and place in anappropriate waste disposal container.

Flammable liquid. Keep away from heat. Keep away from sourcesof ignition. Stop leak if without risk. Absorb with dry earth; sand or

Large SpilllLeak other non-combustible material. Do not touch spilled material.Prevent entry into sewers, basements or confined areas; dike ifneeded.

SECTION 7 - HANDLING AND STORAGEHandling Procedure Handle with care

Store in a segregated and approved area. Keep container in a cool,

.Storage & Condition well-ventilated area. Keep container tightly closed and sealed untilready for use. Avoid all possible sources of ignition (spark or flame)and water also.

Keep away from heat. Keep away from sources of ignition. Groundall equipment containing material. Do not. ingest. Do not breathegas/fumes/vaporlspray. Avoid contact with eyes. Wear suitable

Storage Protection protective clothing. In case of insufficient ventilation, wear suitablerespiratory equipment. Show the container or the label. Keep awayfrom incompatibles such as oxidizing agents, acids, base andalcohols.

Avoid all personal contact, including inhalation. Wear protectiveGeneral Occupational clothing when risk of exposure occurs. Do not cut, drill, grind orHygiene Measures weld such containers. Wash contaminated clothing before reuse.

Discard contaminated shoes. Wash thoroughly after handling.

Remarks on Storage Protect against physical damage. Storage and use areas should beNo smoking areas.


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SECTION 8 - EXPOStJRE CONTROL I PERSONAL PROTECTION

OSHA (PEL) NIOSH (REL)Exposure Limit ACGIHI TLV

None listed None listed None listedTWA

None listed None listed None listedSTEL

Specific Engineering Controls: Provide exhaust ventilation or other engineering controls to keep theairborne concentrations of vapors below their respective threshold limit value. Ensure that eyewashstations and safety showers are proximal to the work-station location

Personal Protection:1. Respiratory Protection: Use respirators and components tested and approved under appropriate

government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows airpurifying respirators are appropriate use a full-face respirator with multi-purpose combination(US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If therespirator is the sole means of protection, use a full-face supplied air respirator.

2. Eye Protection: Chemical safety goggles. Face shield (8-inch minimum).3. Skin !Hands Protection: Compatible chemical-resistant gloves.

Select gloves tested to a relevant standard (e.g. Europe EN 374, US F739).Gloves with a protection class of 5 or higher (breakthrough time greater than 240 minutesaccording to EN 374) and NIOSH approved is recommended.Gloves must only be worn on clean hands. After using gloves, hands should be washed and driedthoroughly. Application of a non-perfumed moisturizer is recommended.OTHERGloves. Full suit. Vapor respirator. Be sure to use an approved/certified respirator or equivalent.Wear appropriate respirator when ventilation is inadequate. Overalls body protection.,Approved SCBA setP.V.C. apronBarrier creamSkin cleansing creamEye wash unit

Thermal Hazards: To avoid thermal hazards ensure the sufficient air flow trough mechanicalventilation system

Environmental Exposure Control: To ensure the health hygiene of workers environmental conditionat work place should be recorded. Avoid the inhalation of fumes by using the appropriate filter /canister mask.Acetyl Chloride is a highly toxic substance in aquatic environmental also. There is growing concordand possible effect on environmental.

SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES

PungentPhysical State &Appearance

Clear, Yellowish liquid. Odour

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Odour Threshold (ppm) Not available Molecular Weight 78.5 g/mole

Color Clear to yellow Melting Point - 112°C

Specific Gravity 1.11@ 20°C/4°C Vapour Density 2.7(air=l)

Vapour Pressure 11.69psi @ 20°C Evaporation Not available(mmHg) Rate/V olatility

Boiling Point 51°C Freezing Point (OC) - 112°C

pH (1% Solution in Coefficient ofNot available Water/Oil Not availableWater) Distribution

Solubility in Water Soluble in water and oil Taste Bitter (Slight)

Ionicity will not occurred Critical Not availableTemperature

Oxidization Property Not available Decomposition Not availableTemperature

Viscosity Not available Dispersion Not availableProperty

SECTION 10 - STABILITY AND REACTIVITY

Chemical Stability..J yesThis product is stable.

Incompatibility with Other ..J yesSubstances With strong oxidizing agents, strong bases, alcohols.

Reactivity and its Conditions:

Reactivity Class 2

Corrosively Class EF

Polymerization Will not occur

Hazardous Decomposition Typical for burning hydrocarbon forms Carbon Dioxide and CarbonProducts Monoxide, Hydrogen Chloride Gas.

SECTION 11 - TOXICOLOGICAL INFORMATION

Effect on Animals Not found

Chronic Effect on Human Dermatitis, scaling, irritating and nervous system dispersion

Toxic Effect on Human None

Irritancy of Product Irritation to eye and skin of8

Rev. # 03 (EffectiveDate: 15.03.2016)

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MATERIAL SAFETY DATA SHEETDoc #: EHS/FI027 Ref SOP #: EHS/SOP/024

Skin Sensitization Skin bum

Respiratory Sensitization Respiratory tract irritation

Carcinogenicity-IARC Not listed Carcinogenicity Not listed(ACGIH)

Reproductive Toxicity No Information Teratogenicity No Information

Embrotoxicity No Information Mutagenicity None

Developmental Toxicity Not available Aspiration Hazard Not available

Specific Target Organ Eyes, skin, mucous Specific Target Organ Central nervous

Toxicity - Single Exposure membranes Toxicity-Repeated system, eyes, skin,Exposure mucous membranes.

Name of Synergistic Not availableProductslEffects

SECTION 12 - ECOLOGICAL INFORMATION

Aquatic Toxicity Not available

BOD & COD Increase BOD and COD

Biodegradation Product Possibly hazardous degradation products are likely.

Toxicity of Biodegradation The product itself and its products of degradation are toxic.Product

SECTION 13 - DISPOSAL CONSIDERATIONS

Waste must be disposed of in accordance with federal, state and localWaste Disposal environmental control regulations,

Federal and State Regulations: Acetyl Chloride is a toxic substance

Waste Code RCRA waste number UOO6

SECTION 14 - TRANSPORT INFORMATION

Special Shipping Information Acetyl Chloride

Transport Classification Class: 3, Sub Class: 8 Property: Highly flammable andexplosive and water reactive.

Identification Acetyl Chloride

Hazchem Code 4WE

TDG This product is classified as Dangerous Goods Class 3.2, packinggroup II.


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Proper ShippingName Acetyl ChlorideHazards Class Class: 3, Sub Class: 8

IMO UNNumber UN: 1717Packing Group II

SECTION 15- REGULATORY INFORMATIONClass B-2: Flammable liquid with a flash point lower than 37.8°C (lOO°F).

WHMIS Classification Class D-2A: Material causing other toxic effects (Very Toxic).Class E: Corrosive liquid.

OSHA None listed

R Phrases:R.II-Highly flammable.R 22-Harmful if swallowed.R 38-Irritating to skin.R 41-Risk of serious damage to eyesRI8-In use may form flammable/explosive vapor-air mixture.R 20/21/22-Harmful by inhalation, in contact with skin and if swallowed.

DSCL (EEC) R 34/ 35-Causes bum and severe bums.R 41-Risk of serious damage to eyes.R 14-Reactsviolently with water.S Phrases:S 16-Keepaway from sources of ignition - No smoking.S 26-In case of contact with eyes rinse immediately with plenty of water andseek medical advice.S 45-Seek medical advice immediatelyS 9-Keep container in a well-ventilated place.

NFPA(USA)

Health Hazard 3 Flammability Hazard 3

Reactivity Hazard 3 Other Hazard Water reactive

SECTION 16 - OTHER INFORMATION

Danger: Flammable liquid and vapor. Corrosive. May cause central nervous system depression. Causeseye and skin bums. May cause severe respiratory tract irritation with possible bums. May cause severedigestive tract irritation with possible bums. Water reactive.

References: http://www.sciencelab.net

Label Precautions: Keep away from heat, sparks and flame and contact of water. Keep container


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MATERIAL SAFETY DATA SHEETDoc #: EHS/FI027 Ref SOP #: EHS/SOP/024

closed. Use only with adequate ventilation along with fume hoods. Wash thoroughly after handling.Avoid breathing vapor. Avoid contact with eyes, skin and clothing.

Label First Aid: Aspiration hazard. If swallowed, vomiting may occur spontaneously, but DO NOTINDUCE. If vomiting occurs, keep head below hips to prevent aspiration into lungs. Never giveanything by mouth to an unconscious person. Call a physician immediately. If inhaled, remove to freshair. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. In case of contact,immediately flush eyes or skin with plenty of water for at least 15 minutes. Remove contaminatedclothing and shoes. Wash clothing before reuse. In all cases, get medical attention.

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