The score: budget cuts, 1; football team, 0

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+ A REVER-BERATINGWIN: The AvonHigh Schoolmarching bandwon for the sec-ond year in a rowat the Bands ofAmerica GrandNational Cham-pionships. Theband performed“Twisted Wonder-land” on Saturdaynight at Lucas OilStadium.Story, B1

Bands of America championships

JOE VITTI / The Star

There’s a guy in town,name is Larry Bird.Throughout the1980s, he was one

half of sport’s greatest teamand individual rivalry — theBoston Celtics and Los An-geles Lakers, Bird and MagicJohnson. He, too, has heardall the talk from the Indian-

apolis Colts and NewEngland Patriots, how

tonight’s nationally tele-vised game is . . . here it

comes . . just another game.“Just another game,” dead-

panned Bird, the IndianaPacers president. “Yeah, right.I don’t buy any of it.”

In the 1980s, when Bird andMagic were saving the NBA,the Lakers and Celtics rarelyplayed during the regular sea-son, given the fact the twoplayed in different confer-

ences. But when that rare game or twogot scheduled every season, they men-tally circled it.

Bob KravitzCOMMENTARY

Think the Colts and Patriots put thisone on their mental day planner whenthe schedule came out?

Bet on it. “The thing is, (before those Celtics-

Lakers games), the emotion, the tensionin the air leading up to it, you could feelit,” Bird said. “Even if we were playingAtlanta on a Wednesday and the Lakerson a Friday, all anybody was talkingabout was the Lakers. Youcouldn’t help but hear it,

EPIC RIVALRYCOLTS VS. PATRIOTS 8:20 P.M. TODAY | COVERAGE IN SPORTS, C1

MANNING-BRADY FACE-OFF IS ONE FOR THE HISTORY BOOKS

ROBERT SCHEER / The Star WINSLOW TOWNSON / Associated Press

Whether in movies, stories or sports, highly charged matchups are always fun to watch.Can you name all of the famous rivals below? (For answers, see Page A2.)

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The Star’s position: Corporations and special-interest groups arepouring a record amount of money into the Indiana Statehouse toinfluence, and even to help write, state laws. It’s time for Hoosiersto demand reform. Conversations, B9-10

By John Russelljohn.russell@indystar.com

In a corner of an Eli Lilly and Co.cancer laboratory, biologist Julie Po-meroy squeezes drops of a fluorescentstain onto mice tumor tissues, trying tomake their mysterious world more vis-ible under a microscope.

One room away, Dr. Mark Uhlik, asenior research scientist, pulls up theimages on a computer screen. The tu-mor, marked in yellow, is fairly small.But it is surrounded by globs of bloodvessels in green, support cells in red

and the nucleus inblue.

The colors, Uhlikthinks, could give himvaluable clues abouthow to attack a tumorand, more impor-tantly, its surroundingenvironment.

For years, cancerresearchers focusedtheir efforts on just

killing the tumor, ignoring the sur-rounding matter — with limited suc-cess. The tumors often swelled backup, nourished by the blood and tissuessurrounding it.

Now, researchers at Lilly think a tu-mor’s whole environment is important.Maybe the best way to kill a tumor,they say, is to choke off its blood sup-ply, starving it to death.

“Are we hitting our target?” Uhlikasks, looking at the colors on thescreen to see if they are being affectedby the various experimental drugs.

Dozens of times a day, hundreds oftimes a week, the researchers and lab

Lilly’s bigcancer bet:

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Risks, potential rewardsare huge for drug maker

» See Lilly, Page A16

+ CANCERFIGHT: A lookat what cancerdrugs Lilly hasand the 23compounds it’sworking on toattack the dis-ease. A16

Deep in the back ofManual High School,in a room just beyondthe main auditorium,

you can find the school’s history.It can be discovered in year-

books dating back a century; inyellowed school newspapers;and, among other clippings andpapers, in a framed black-and-white photograph of Manual’sundefeated 1958 football team.

The school’s alumni associa-tion, a dedicated group of senior

citizens, manages the room withcare. Many of them have e-mailed and called me in recent

months to reminisce about theManual they remember, the onebubbling with school spirit andtradition. Over and over, they’vetold me Manual was the placeto be in their day.

But the group hasn’t hadmuch material to add to itsroom lately.

Manual hasn’t had a schoolnewspaper or yearbook in years,and student participation in

The score: budget cuts, 1; football team, 0

» See Tully, Page A17

Matthew TullyCOMMENTARY

» MANUAL PROJECT This is the 13th in an occasional series of columns Matthew Tully is writing about life atManual High School. Follow Tully’s reports throughout the school year as he explores Manual through the eyes ofteachers, administrators, students and parents at IndyStar.com/Manual.

Butler comes from behind for a season-opening victory against Davidson. >> C1

» See Kravitz, Page A23

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many clubs and activities is low.Now comes word that the

school is losing its football team,a victim of budget cuts and theinability to round up enoughstudent-athletes to field a fullteam.

By the end of this season,coach Cedric Lloyd was leftwith only 17 players — a team sosmall that most players wereforced to play both offense anddefense. Each week, his teamtook on schools with bigger ros-ters and stronger programs.Manual lost every game itplayed this year.

Still, in a school with a mea-ger 39 percent graduation rate,17 young men worked andstayed in school and gave whatthey had. Students in theschool’s band played faithfullyfrom the mostly empty standsweek after week. A small groupof cheerleaders kept working torally support, even on cold andrainy nights when their teamwas losing by 40 points.

It wasn’t enough.After years of warnings, Indi-

anapolis Public Schools Superin-tendent Eugene White an-nounced last week he’d hadenough with schools thatcouldn’t produce strong sportsprograms. Manual’s footballteam, despite a history thatstretches to the late 1890s, isnow history itself.

With this depressing news,another piece of Manual disap-pears. Another staple of highschool life leaves the building.Another avenue to keep stu-dents in school is lost. Along theway, the cruel gap between aschool in the heart of the cityand those in the townships andsuburbs widens further.

It’s a cold decision. And whileWhite makes a rational bottom-line argument on behalf of themove, it’s one he should recon-sider.

Manual needs to offer its stu-dents more options, not fewer.Its leaders need to be able toconvince students and parentsthat they are fighting to improvelife at Manual, rather than giv-ing up in the face of struggles.

Football isn’t Manual’s topconcern, of course. Guidingmore students into calculus,other advanced classes and ulti-

mately to graduation are farmore important goals. But imag-ine a high school without even afootball team.

“It’s going to feel a lot morebleak,” junior Donald Tener toldme. “A lot of schools are identi-fied by their football teams. Butnot this one.”

The news comes at a particu-larly bad time. As I’ve writtenmany times this year, Manual’sproblems are enormous and nu-merous. But many teachers, stu-dents and ad-ministrators aretrying hard torevive theschool. The evi-dence is there —in the growingchoir program,in the small butloyal drama club,in the bandroom and in thepush to bringback the schoolpaper and yearbook.

“We’re trying to build extra-curricular programs. We reallyare,” Principal Richard Grismoresaid as we sat in his officeWednesday afternoon. “But herewe are now, losing a major pieceof that.”

White shared the news withthis newspaper before tellingthe school’s leaders. So Gris-more found out about his foot-ball team’s fate, and his highschool’s latest headache, whilescanning The Indianapolis Star’ssports section over his morningCheerios on Wednesday.

“I’m surprised,” he said. “I’mdisappointed. But I knew (Su-perintendent White) was look-

ing at this.”Near Grismore’s office, senior

DeJuan Parker stood byManual’s front door waiting foran after-school ride. He playedwide receiver this season andsaid football helped him stayfocused on school. Studentsmust have a C average to playon the team, and although thatcost coach Lloyd many potentialplayers, it was a motivator forothers.

“It really helped some kids,”DeJuan said.“The kids whoplay graduate.Now you havethat big field outthere. What areyou going to dowith it?”

Not much.The footballfield behindManual HighSchool will situnused next

year. There will be no reason tohead to Manual on fall Fridaynights.

The other day I talked tocheerleader Tricia Tharpe, ahard-working student who getsgood grades and works afterschool at a pizza joint. She de-fends Manual but said she andother friends talk frequentlyabout the lack of school spirit.

“It’s not there,” she said. “Wetry to get people excited at thegames, but it’s hard.”

At least she tried. Unlike IPS,which has given up — at least inone way — on Manual.✭ Reach Matthew Tully at (317) 444-6033 or via e-mail atmatthew.tully@indystar.com.

Tully» Principal read aboutteam’s fate in the paper.

From A1

DANESE KENON / The Star

SETBACK: Manual Principal Richard Grismore, seen at an October peprally, says he’s surprised and disappointed at losing the football team.

By Jennifer LovenAssociated Press

SINGAPORE — A major pactwithin tantalizing reach, Presi-dent Barack Obama aims tonudge forward an arms-controldeal in talks with Russian Presi-dent Dmitry Medvedev.

The 21-nation Asia-PacificEconomic Cooperation forumbrought Obama to Singapore, buthe is focusing on individual meet-ings today with Medvedev andIndonesia’s Susilo Bambang Yud-hoyono, president of the world’slargest Muslim nation and Oba-ma’s home as a boy.

The U.S.-Russia meeting takesplace as the nations seek a suc-cessor to a Cold War-era agree-ment.

Obama planned another mile-stone: joining a larger meetingthat includes the leader of mili-tary-ruled Myanmar. Obama issure to face criticism at home,particularly from conservatives,for doing so — a significant stepup in his administration’s newpolicy of “pragmatic engage-ment” that is a shift from years ofU.S. isolation and sanctions.

The leaders at the APEC forumalso planned an informal break-fast meeting, organized by Aus-tralian Prime Minister KevinRudd and Mexican President Fe-lipe Calderon, to discuss theprogress of negotiations on a cli-mate change agreement.

Obama and Medvedev agreedin April to reach a new nucleararms reduction treaty to replaceStrategic Arms ReductionTreaty 1 before it expires on Dec.5. Later, in Moscow in July, theyagreed further to cut the numberof nuclear warheads each nationpossesses to between 1,500 and1,675 within seven years.

U.S. officials say the two na-tions now have agreed on thebroad outlines of a new treaty,with the expectation that the

leaders will sign one during Oba-ma’s travels to Europe in earlyDecember to accept the NobelPeace Prize.

Such an agreement would be abig feather in Obama’s cap andbragging rights toward his prom-ise to work toward a nuclear-freeworld, offering momentum forother arms-control and nonpro-liferation efforts. The presidenthas been hinting at his optimismon the issue leading up to andduring his Asia trip.

“We are already taking steps tobring down our nuclear stock-piles in cooperation with the Rus-sian government,” he said duringa news conference in Japan withPrime Minister Yukio Hatoyama.

A new treaty also could boostrelations with Russia at a timethat Washington is looking for itscooperation on reining in Iran’snuclear ambitions and other is-sues.

Negotiators already haveworked through a number of con-tentious issues and agreed on thenumber of warheads, the numberof delivery systems and what willcount as a delivery system, offi-cials said.

Once a deal is signed, it stillwould need to be ratified by theRussian Duma and the U.S. Senateto take effect.

Obama to pusharms control deal

with MoscowPresident will continue

talks with Russianleader at Asian forum

VINCENT THIAN / Associated Press

WELCOME: President Barack Obamagreeted Singapore’s Prime MinisterLee Hsien Loong before Saturday’sdinner for APEC leaders.

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IPS SuperintendentEugene White saidlast week thatsagging participationalso forced him toend the footballprograms at Marshalland Washington highschools.