Post on 17-Jan-2018
description
Slide 1
superoxide dismutase catalase
Figure 6.1Page 96Do not post
on Internet
Slide 2
Caenorhabditis elegans
Figure 6.2Page 97
Slide 3
product with more energy(plus by-products
602 and 6H2O)
Energy In
energy-poorstarting substances 6 12
Endergonic reaction
Energy Out
energy-rich starting substance
+602
products with less energy6 6
Exergonic reaction
Stepped ArtFigure 6.5a,b
Page 100
Slide 4
Energy inputrequired
Potential energy released
Stepped ArtFigure 6.5c,d
Page 100
Slide 5
ATPForms
Cellular Work
Energy Releasing Reactions
Energy Requiring Reactions
Figure 6.6aPage 101
Slide 6
three phosphate groups
sugar (ribose)
Figure 6.6bPage 101
nucleotide base (adenine)
Slide 7
ribose
Stepped ArtFigure 6.6cPage 101
adenine
ATP
P P P
ADP
P P
AMP
Slide 8
energyinput
ADP + Pi
ATP
energy output
In-text figurePage 101
Slide 9
Figure 6.7Page 101
Ca++
Ca++ Ca++
Ca++
Ca++
Ca++Ca++
Ca++
ATP
ADP Pi
energy input energy output
Slide 10
A B C D E F
Figure 6.8Page 102
Linear Pathway:
FA B C D E
Branching Pathway:
K J
M LN
Cyclic Pathway:
G
H
I
Stepped Art
Slide 11
HighlySpontaneous
Equilibrium
HighlySpontaneous
Relative Concentrationof Product
Relative Concentrationof Reaction
Figure 6.9Page 103
Slide 12
Glucose-1-phosphate Glucose-6-phosphate
Figure 6.10Page 103
Slide 13
H2 1/2 O2 H2
2H+ 2e-
2H+
2e-
1/2 O2
H2O
1/2 O2
H2O
Explosiverelease ofenergy asheat cannot beharnessedfor cellularwork
2.Electronstransferred throughan electron transfer system
1. Water molecules split; hydrogen ions, electrons, oxygen released
3. Somereleasedenergy isused to make ATP
electric spark
Figure 6.11a,bPage 104
Slide 14
sunlight
electron transfer chains(dark green)
H2O
NADP+e-
NADPH
H+ concentration and electric gradients build up and are used to drive ATP formation
Figure 6.11cPage 104
Slide 15
activation energywithout enzyme
activation energywith enzyme
energyreleasedby the
reaction
products
starting substance
forward reaction
Figure 6.12aPage 105
Slide 16
ENZYME!
Figure 6.12bPage 105
Slide 17
Action of catalase
heme group
histidine
hydrogen peroxide
Stepped ArtFigure 6.14Page 107
Slide 18
allosteric activator
vacantallosteric binding site
active site altered, can bind substrate
active site cannot bind substrate
enzyme active site
Allosteric activation
allosteric inhibitor
allosteric binding site vacant; active site can bind substrate
active site altered, can’t bind substrate
Allosteric inhibition
Stepped ArtFigure 6.15a,b
Page 108
Slide 19
enzyme 2 enzyme 3 enzyme 4 enzyme 5
enzyme 1
SUBSTRATEEND
PRODUCT (tryptophan)
Excess end product molecules bind with molecules of enzyme 1.
The greater the excess, the more enzyme molecules are inhibited and the greater the decrease in tryptophan synthesis.
Feedback Inhibition
Figure 6.16Page 108
Slide 20
Animation
Click to view animation.
Feedback inhibition animation.
Slide 21
Figure 6.17bPage 109
Slide 22
Figure 6.17cPage 109
Slide 23
Firefly LuciferaseFigure 6.19c
Page 110
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