Post on 10-Dec-2015
description
Schematic diagram
-initial infection happens.
2-4 days after initial infection Primary viral replication occurs
4-6 days post-infection Second viral Infection
14-16 days post-infection
Susceptible Person
*Immunocompromised
*No known history of Varicella Zoster infection
*non-immunized by any form of Varicella Vaccine
Varicella Zoster Virus
Mucosae of the upper Respiratory tract
Sneezing
Coughing
Contact with blisters
Conjunctivae
Regional Lymph nodes
(Viral proliferation occurs)
Liver, spleen and other organs.
Invasion of the capillary endothelial cells, exit into the capillaries and spread into the dermis and epidermis
INFECTED PERSON
Centripetal Vesicular Rash
Low-grade fever, Myalgia, Body malaise, nausea ,anorexia,
headache