ROLE OF INSULINAND IT’S

ALTERATION IN DM.

Prepared by: Fahad AlHulaibiKing Faisal University

College of medicine

ROLE OF INSULIN Insulin is protein hormone, secrated after

male by B-cells. Response in rising of blood glucose

(glycogenesis). Effect metabolism of CHO, fat & protein. < glucose production & > glucose

uptake By translocation GLUT4. Stimulate lipogenesis in liver. And

inhabit lipolysis (inhabit fat catabolism).

IN DM. In DM, insulin deficiency.. or insulin resistance.. Glucose level will be high.

Hyperglycemia. Other complications