Role of insulin & it's alteration in Diabetes Mellitus

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ROLE OF INSULIN AND IT’S ALTERATION IN DM . Prepared by: Fahad AlHulaibi King Faisal University College of medicine

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Role of insulin & it's alteration in Diabetes Mellitus

Transcript of Role of insulin & it's alteration in Diabetes Mellitus

Page 1: Role of insulin & it's alteration in Diabetes Mellitus

ROLE OF INSULINAND IT’S

ALTERATION IN DM.

Prepared by: Fahad AlHulaibiKing Faisal University

College of medicine

Page 2: Role of insulin & it's alteration in Diabetes Mellitus

ROLE OF INSULIN Insulin is protein hormone, secrated after

male by B-cells. Response in rising of blood glucose

(glycogenesis). Effect metabolism of CHO, fat & protein. < glucose production & > glucose

uptake By translocation GLUT4. Stimulate lipogenesis in liver. And

inhabit lipolysis (inhabit fat catabolism).

Page 3: Role of insulin & it's alteration in Diabetes Mellitus

IN DM. In DM, insulin deficiency.. or insulin resistance.. Glucose level will be high.

Hyperglycemia. Other complications

Page 4: Role of insulin & it's alteration in Diabetes Mellitus