Reporting on Scientific Journal Articles (Jeremy Moore, M.A.)

8/7/2019 Reporting on Scientific Journal Articles (Jeremy Moore, M.A.)

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Reporting on Scientific

Journal Articles

Jeremy Moore, M.A.

Senior Manager, Science Communications

American Association for Cancer Research

jeremy.moore@aacr.org

Why is Cancer Newsworthy?

Number 1 cause of death, surpassing heart disease in 2010

In the United States, it affects one in threewomen and one in two men

Consequences both biological and psychological

Government Money

NCI Budget, 2009: $4.96 billion

Government Money

Budget Request for 2011

$5.26 Billion

Private Money

Corporate and Philanthropic

Scientific Inquiry

In fact I have not failed 1,000 times.

I have successfully discovered 1,000

ways not to make a light bulb.--Thomas Edison

Scientific Inquiry

Cancer

Scientific Inquiry

Cancer

Out of control cell growth

Scientific Inquiry

Cancer

Out of control cell growth

More than 200 diseases

Cancer

CONTROL

Cancer: The Scientific Questions

Diagnosis

Bladder Cancer

Pancreatic Cancer

Ovarian Cancer

Breast Cancer

Colon Cancer

Skin Cancer

Diagnosis

Screening

Questions surrounding PSA, Mammography,Colonoscopy

Sensitivity vs. Specificity

Sensitivity

Correctly Identifying WhoIs Sick

Specificity

Correctly Identifying WhoIs Not Sick

MicroRNA

The discovery of MicroRNA can be equated withthe idea that weve known for years that cars

existed and only recently discovered they have a

transmission. Its that fundamental.Philip Sharp, Ph.D., Nobel Laureate from M.I.T.

MicroRNA News from AnnualMeeting 2010

miR-21 and miR-106a are associated with anoverall poor prognosis and that overexpressionsof miR-181b and miR-203 are associated with

poor outcomes in blacks for colorectal cancer MicroRNA-31 (miR-31) repressed specific tumor

suppressors and, therefore, may be a novelpharmacologic target for lung cancer therapy

and chemoprevention.

MicroRNA News from AnnualMeeting 2010

High levels of miR-21 were significantlycorrelated with poor response to Herceptin.

DNA Methylation Levels

Diagnosis

Screening

Personalized Medicine

PersonalizedMedicine

Diagnosis

Screening

Personalized Medicine

Prevention

At least half of all cancer deaths are preventableby what we already know about healthy eating,

exercise, maintaining appropriate weight,

avoiding smoking and going for regularscreenings.

Ernest T. Hawk, M.D., M.P.H.

Vice President of the Division of Cancer Preventionand Population Sciences at The University of

Texas M. D. Anderson Cancer Center.

Prevention

Healthy Living

Prevention

Healthy Living

Chemoprevention

Prevention

Scientific Inquiry

75 Clinical Trials

11 Systematic Reviews

Are Being Published Every Single Day

Bastian H, Glaszio P, Chalmers I, et al. (2010). Seventy-Five Trials and Eleven Systematic Reviews a Day: How Will WeEver Keep Up? P LOS Med 7 (9): e1000326. doi:10.1371/journal.pmed.1000326.

Journals to Watch

New England Journal of Medicine

Journals to Watch

Journal of the American Medical Association

Journals to Watch

Cancer

Journals to Watch

Cancer

Journal of Clinical Oncology

Journals to Watch

Cancer Research

Journals to Watch

Cancer Research

Clinical Cancer Research

Journals to Watch

Cancer Research

Cancer Epidemiology, Biomarkers & Prevention

Journals to Watch

Cancer Research

Cancer Prevention Research

Journals to Watch

Cancer Research

Cancer Prevention Research

Molecular Cancer Research

Molecular Cancer Therapeutics

NEWS FLASH

CANCER DISCOVERY

NEWS FLASH

CANCER DISCOVERY Officially announcing next week

NEWS FLASH

Editors in Chief, Jose Baselga, M.D, Ph.D. and Lewis

Cantley, Ph.D.

NEWS FLASH

Editors in Chief, Jose Baselga, M.D., Ph.D., and Lewis

Cantley, Ph.D.

Will be the premier venue for the publication andbroad dissemination of high impact research in allareas of cancer research

NEWS FLASH

Cantley, Ph.D.

Will be the premier venue for the publication andbroad dissemination of high-impact research in allareas of cancer research.

First papers will be published online April 2011

NEWS FLASH

Cantley, Ph.D.

Will be the premier venue for the publication andbroad dissemination of high-impact research in allareas of cancer research

First papers will be published online April 2011 In Print July 2011

THE ANATO MY OF AN ABSTRACT

Conclusions, not titles

Population Samples

Statistics

P Values, anything less than .05 is significant

Statistics

P Values, anything less than .05 is significant

Hazard Ratios

HR=1.23, 95% CI, 1.05-1.10

FOLLO W THE NEWS

Subscribe to Newswise

Check Eurekalert

Find a PR Person you trust

KEEP IN TOUCH

Jeremy Moore

Senior Manager, Science Communications

Office: 267-646-0557

Cell: 609-519-0212

jeremy.moore@aacr.org

THANK YOU

Reporting on Scientific Journal Articles (Jeremy Moore, M.A.)

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