Oct 13, 2005 GW Canters Leiden Univ 1

I I . Superstructures/patterns

A. DNA based superstructures

B. Patterning

C. Protein based superstructures

D. Supramolecular Chemistry

Oct 13, 2005 GW Canters Leiden Univ 2Nature 421(2003)427

Oct 13, 2005 GW Canters Leiden Univ 3

Bioch.Soc.Trans. 32(2004)51

Oct 13, 2005 GW Canters Leiden Univ 4

I I . Superstructures/patterns

A. DNA based superstructures

B. Patterning

C. Protein based superstructures

D. Supramolecular Chemistry

Oct 13, 2005 GW Canters Leiden Univ 5

Oligonucleotide 40 has a sequence of 17 bases; its 3 end is modified with athiol group (5-GTAAAACGACGACGGCCAGT-SH-3). The 57-baseoligonucleotide 41 includes a central sequence complementary to 40 andside sequences of alternating A and T bases. Oligonucleotide 42 is a 50-basepoly(A-T) that forms a network structure upon contact with 41. All threeoligonucleotides were mixed with 5-nm Au NPs. The resulting network wasadsorbed onto a mica surface, and the surface was probed by AFM

Angew.Chem. 43(2004)6042

Oct 13, 2005 GW Canters Leiden Univ 6

I I . Superstructures/patterns

A. DNA based superstructures

B. Patterning

C. Protein based superstructures

D. Supramolecular Chemistry

Oct 13, 2005 GW Canters Leiden Univ 7

G. Ali Mansoori, “Principles of nanotechnology” (2005) World Scientific Publishers

Angew.Chem. 43(2004)6042

Oct 13, 2005 GW Canters Leiden Univ 8

Angew.Chem. 43(2004)6042

Oct 13, 2005 GW Canters Leiden Univ 9

I I . Superstructures/patterns

A. DNA based superstructures

B. Patterning

C. Protein based superstructures

D. Supramolecular Chemistry

Oct 13, 2005 GW Canters Leiden Univ 10Accts. Chem. Res. 34(2001)433

Oct 13, 2005 GW Canters Leiden Univ 11

JACS 123(2001)12632

Oct 13, 2005 GW Canters Leiden Univ 12

Accts. Chem. Res. 34(2001)433