Post on 21-Aug-2020
M.Phil. CHEMISTRY SEM SUB CODE COURSE SUBJECT TITLE
HRS / WEEK
CREDIT CIA
Mark ESE
MARK TOTAL MARK
I
20MPCH1CC1 Core – I Research methodology in chemistry 4* 4 25 75 100
20MPCH1CC2 Core – II Advanced physical methods and molecular modelling in chemistry
4* 4 25 75 100
20MPCH1CC3 Core – III Teaching and learning skills 4* 4 25 75 100
20MPCH1CC4
Core - IV (Elective)
Paper on topic of research (the syllabus will be prepared by the guide and examination will be conducted by the COE)
4* 4 25 75 100
*One hour library for each course
TOTAL 16* 16 100 300 400
II 20MPCH2PD
Dissertation## - 8 - - 200
GRAND TOTAL - 24 - - 600
## Evaluation of the Dissertation and Viva Voce shall be made jointly by the Research Supervisor and
the External Examiner.
Course Outcomes:
1. Scholars shall identify various ways to design a research problem.
2. Scholars shall develop the numerical aptitude and computational knowledge in the
fundamental of collection and presentation data
3. Scholars shall get innovative idea for their research work based on the compilation of
literature
4. Scholars shall acquire knowledge for writing and publishing the research paper and
drafting the thesis
5. Scholars shall understand the role of statistical analysis of data in research
6. Scholars shall learn basic concepts of computer knowledge for presentation of
dissertation.
Unit - I Principles of Research 12 hours
Definition - Need for research. Objectives – Motivation – Types of research –
Significance - Formulation of Research Problem – Developing Hypothesis - Preparing
Research Design - Selection of Research Problem – Determining Sample Design
Characteristics of a Good Sample Design - Collection of Data – Methods of Data Collection -
Execution of Work. Analysis of Data – Hypothesis, Testing - Generalization and
Interpretation - Preparation of Report - #Submission of Report in the form of Thesis #
Unit - II Survey of Literature 12 hours
Need for literature survey – Primary, Secondary and Tertiary Sources. Journals,
Chemical Abstracts – Subject index, Substance index, Author index, Formula index and other
indices. Other similar abstracts for special topics. Current Titles – Reviews – Monographs –
Selection of Research topic – Selection of Research Facility – Location of Journals and
Articles. Use of computers in the Literature Survey – Websites – Search Engines -
chemspider, google scholar, scifinder, scopus, Internet, E-mail. #Scientific Information and
Documentation Centers – INSDOC, BANSDOC, NCSI, British Library – Digital Library –
e-Journals – e-Content #.
Unit - III Assignment, Research Paper and Thesis Writing 12 hours
Assignment – Topic selection, Front Page, Text and References. Research Paper –
Preparation of Manuscript for Publication in International Journals Published by Elsevier,
Interscience, Wiley and Springer- submission procedure. Thesis - Rough drafting – Title,
Abstract, Introduction, Scope of the Work, Literature Review, Problem and Time Limitation,
Experimental Methods, Results and Discussion Foot Notes- Data Presentation - Figures and
Tables, Sign Conventions followed, bibliography, Conclusion and Recommendations.
Abbreviations used. #Storing and Retrieval of Information using Computer – CD, Pen Drive,
DVD#.
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC1 Core – I RESEARCH METHODOLOGY
IN CHEMISTRY 4 4 100 25 75
Unit – IV Statistical Analysis of Data 12 hours Various types of errors – precision and accuracy – significant figures, various statistical tests on
the accuracy of results, positive and negative deviation from accurate results – the Gaussian distribution
– the normal distribution of random errors, mean value, variance and standard deviation, reliability
interval, deviations from the Gaussian law of error distribution, t-tests- comparison of the mean with the
expected value, comparison of the results of two different methods, comparison of the precision of two
methods by F-test, Gross errors and elimination of outlying results, graphical methods – Linear
regression, regression line, # standard deviation, correlation coefficient#–Multiple Linear regression (one
variable with two other variables).
Unit – V Computer Application Skill 12 hours
Internet – meaning and importance, types of networking – LAN, WAN and MAN – Internet –
WWW, website and webpage’s, mode of connection, network protocol, browsing the internet –
browsing softwares, URL addresses, domain name, search engines, exploring websites and downloading
materials from websites, E-mail – sending, receiving and storing mail and chatting. Power point –
creating a presentation – slide preparation – # popular websites for data collection in chemistry#.
#............ # Self study TEXT BOOKS 1. Research Methodology (Methods & Techniques), C.R. Kothari. 2nd Edn., Wishwa Prakasam,
2002. 2. Analytical Chemistry, Scoog, West, Holler and Crouch. Thomson – India 8th Edn., 2007. 3. Zikr – ur Rahman , Modern teaching methods and techniques , Anmol Publication Pvt. Ltd. New Delhi,
(2006). 4. T. M. Srinivasan, Use of Computers and Multimedia in Education, Aavisakar publication, Jaipur (2002). UNIT I : Text Book 1 UNIT II : Text Book 1 UNIT III : Text Book 1 UNIT IV : Text Book 2 UNIT V : Text Book 3,4 REFERENCES 1. Thesis and Assignment writing, J. Anderson, B.H. Durston and M.Poole, John Wiley
Publications, Sydney. 1970. 2. How to write a research paper, R. Berry, Pergoman, 1969. 3. Computers in Chemistry, K.V. Raman, Tata McGraw-Hill Publishing company Limited, New
Delhi, 2005.
4. Analytical Chemistry (Theory and Practice) by R.M. Verma. CBS Publishers and
Distributers, 2001.
Relationship Matrix for Course Outcomes, Programme Outcomes and Programme Specific
Outcomes:
Semester Code Title of the Course Hours Credits
I 20MPCH1CC1 Research Methodology in
Chemistry
4 4
Course
Outcomes
(COs)
Programme Outcomes
(POs)
Programme Specific Outcomes
(PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1 PSO2 PSO3 PSO4 PSO5
CO1
CO2
CO3
CO4
CO5
Number of Matches= 35 Relationship is : High
Prepared by: Checked by: Dr.A.Jahir Hussain Dr.Syed Abuthair
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC2 Core – II ADVANCED PHYSICAL
METHODS AND MOLECULAR MODELLING IN CHEMISTRY
4 4 100 25 75
Course Outcomes:
1. Categorize the features of nonmaterial’s based on their applications.
2. Predict complicated structures using correlation technique
3. Deduce the geometry and magnetic properties of inorganic complexes.
4. Analyse the molecular interactions by adapting molecular modelling.
5. Assess the Drug ability of a molecule by simulation method.
Unit I - Characterization and applications of nano materials 12 hours Surface morphology and nanostructure – Scanning Electron Microscope (SEM), Transmission
Electron Microscope (TEM) and Atomic Force Microscope (AFM); #Structural Characterization - UV-
Visible and FT-IR spectroscopy#; Structure orientation and micro texture-X-ray Diffraction (XRD);
Elemental analysis – Energy Dispersive X-ray Micro analysis (EDX) and Atomic Absorption
Spectroscopy(AAS).
Applications of carbon nanomaterials in the field of fuel cells and batteries; Energy and
environmental applications- Energy production and storage - Applications of nanomaterials in electronics-
semiconductors and chemical sensors, biotechnology- detection of biomolecules and medicine-drug design
and drug delivery.
Unit II– 2D-NMR and NQR spectroscopy 12 hours
2D- NMR – basic principle and types-homonuclear through-bond correlation methods-Correlation
spectroscopy (COSY- 1H-
1H COSY &
1H-
13C COSY), Exclusive correlation spectroscopy (ECOSY), Total
correlation spectroscopy (TOCSY), Incredible natural-abundance double-quantum transfer experiment
(INADEQUATE)- Heteronuclear through-bond correlation methods-Heteronuclear single-quantum
correlation spectroscopy (HSQC), Heteronuclear multiple-bond correlation spectroscopy (HMBC)- Through-
space correlation methods-Nuclear Overhauser effect spectroscopy (NOESY), Rotating frame nuclear
Overhauser effect spectroscopy (ROESY)-# Resolved-spectrum methods-Higher-dimensional methods
#.
NQR spectroscopy – Characteristics of quadrupolar nucleus – effects of field gradient and magnetic
field upon quadrupolar energy levels – NQR transitions – applications of NQR spectroscopy.
Unit – III –Inorganic Spectroscopy 12 hours 31
P, 14
N and 15
N NMR spectra – basic theory, standard reference, chemical shift, coupling constants
and biological applications.Combined applications of UV-Visible, FT-IR, Raman and EPR spectral data for
solving the structure of metal (Co, Ni, Cu and Zn) complexes- #1
H-NMR spectra of zinc complexes#-
Magnetic studies for the characterization of the complexes by VSM.
Unit -IV Molecular Modeling-I 12-hours
Molecular Modeling – definition and importance-types of molecular model- spheres, ball-and-stick,
skeletal, polyhedral, composite and computer-based models- molecular mechanics- software for molecular
mechanics modeling - coordinate systems- potential energy surfaces- molecular graphics- definition, relation
with molecular models- #non-bonded interactions- electrostatic and van der Waals interactions in molecular
modeling#- hydrogen bonding in molecular mechanics.
Unit-V Molecular Modeling –II 12-hours Computer simulation methods- definition and advantages- data preparation and process for the
preparation of computer simulation model- softwares for simulation- differences between simulation and
model- types of simulation models- force field model for the simulations of liquid water-#calculation of
simple thermodynamic properties, phase space#, drug design and delivery using simulating models.
#......... # Self study
BOOKS FOR STUDY
S.
No. Author Name Book Name Edition Publisher detail
Year
1 F. J. Ownes Introduction to Nano technology - John Wiley and New
Jersey
2003
2 P.S.Kalsi Spectroscopy of Organic
Compounds 6th Edition
New Age International
Publishers. 2007
3 William Kemp NMR in Chemistry - Macmillan Education
Ltd, London 1986
4. R. S. Drago
Physical Methods in Chemistry - W. B. Sounders 1983
5. Alan Hinchliffe
Molecular Modelling for
Beginners 2
nd Edition Wiley Publication 2008
6. Andrew R. Leach
Molecular Modelling 2
nd Edition
Pearson Prentice Hall, England
2001
1. , UNIT I: Text Book 1 UNIT II: Text Book 2 UNIT III: Text Book 3, 4
UNIT IV: Text Book 5 UNIT V: Text Book 6
BOOKS FOR REFERENCES
S.
No. Author Name Book Name Edition Publisher detail
Year
1 B. P. Straughan and S.
Walker
Spectroscopy, Vol. 1 - Chapman and Hall
1967
2 H. Kaur
Spectroscopy 3rd Edition
Pragati Prakasan
Publications, Meerut 2006
3
E.AV.Ebsworth,
W.H. Rankin and
Cradock
Structural Methods in
Inorganic Chemistry - ELBS 1987
4.
Robert M.
Silverstein, Francis
X.Webster, David
Kiemle
Spectrometric
Identification of Organic
Compounds - John Wiley & sons 2005
5.
A.K.Srivastava
and P.C.Jain
Instrumental approach to
chemical analysis 4th revised
Edition S.Chand company
Ltd. 2009
6.
Willard, Merrit,
Dean and Settle
Instrumental Methods of
Analysis 6th Edition
CBS Publishers and
Distibutors 1986
Relationship Matrix for Course Outcomes, Programme Outcomes and Programme Specific
Outcomes:
Semester Code Title of the Course Hours Credits
I 20MPCH1CC2 ADVANCED PHYSICAL
METHODS AND MOLECULAR
MODELLING IN CHEMISTRY
4 4
Course
Outcomes
(COs)
Programme Outcomes
(POs)
Programme Specific Outcomes
(PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1 PSO2 PSO3 PSO4 PSO5
CO1 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO2 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO3 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO4 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO5 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
Number of Matches=39, Relationship is : HIGH
Prepared by: Checked by:
Dr.M.Purusothamam Dr.Syed Ali Badusha
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC3 Core – III TEACHING AND LEARNING
SKILLS 4 4 100 25 75
Course Outcomes
1. Compare and differentiate communication and interaction methods
2. Build educative skill
3. Plan teaching strategies
4. Compose teaching materials using technologies
5. Assess the students by guidance and counselling
Unit - I 12 hours
Communication and Interaction The theory of communication – communication cycle – Types of communication,
communication and language, communication in the class room, Lecture and Lecture demonstration as
communication. Interaction methods – Interaction analysis, observation schedule and record. Bale’s
interaction process categories – Flander’s system of interaction analysis – verbal interaction category
system. #Reciprocal category system – Equivalent talk categories#.
Unit – II 12 hours
Educative Skill
Psychology – Definition – Nature – Meaning of Educational Psychology – Definition – Nature –
Scope. Teaching and learning – meaning – characteristics –effective teaching – concept of learning –
comparison between teaching and learning. Mental health – Frustration –# concept of adjustment –
Defence mechanism# – Mental hygiene.
Unit – III 12 hours
Uses of teaching strategies
Group methods of instruction – lecture – demonstration – seminars – workshops – case analysis
– panel discussion – team teaching – individual approaches – Teleconferencing – Video conferencing –
Description – Advantages – Micro teaching –Characteristics of Micro teaching – Teaching skills -
Programmed Instruction - Computer Assisted Instruction (CAI) – # Language Laboratory#.
Unit – IV 12 hours
Educational Technology
Educational technology – definition – objectives – teaching technology – characteristics of
teaching technology – behavioral technology – pedagogy of teaching – General advantage of using
teaching aids – Broad classification of teaching aids – Hardware and software in teaching aids.
Instructional media – media attributes – multimedia and instructional development – # Multimedia
centre – uses and abuses of multimedia#.
Unit-V 12 hours
Guidance and Counselling
Meaning and definition of Guidance and Counselling- need for guidance – aims of
guidance- nature of guidance - principles of guidance philosophy- types of guidance-
educational, vocational, personal and social guidance- benefits of guidance- benefits to
students, teachers, parents community and administrators – role and functions of guidance
cell – Counsellor-definition, qualities of a good counsellor, characteristics of counselling,
#types of counselling# class teacher as a counsellor- specific duties of a teacher in guidance
service, differences between guidance and counselling.
#......... # Self study
Text Books
S.
No. Author Name Book Name Edition Publisher detail
Year
1 Zikr – ur Rahman
Modern Teaching
Methods and
Techniques
5th
Edition
Anmol
Publications Pvt
Ltd, New Delhi
2000
2 R. A. Sharma
Educational
technology and
management models
media and methods
- R. Lall Book
Depot. Meerut 2007
3 Vanaja Educational
technology
7th
Edition
Neel Kamal
publications Pvt.
Ltd. Hyderabad
2016
4.
K. Nagarajan and
Deva
Seetharaman
Psychology of
learning and Human
Development
2nd
Edition
Sriram Publishers,
Chennai 2014
Books for References
S.
No. Author Name Book Name Edition Publisher detail
Year
1 Bn Dash
Elementary
Educational
Psychology and
Methods of teaching
-
Neel Kamal
publications Pvt.
Ltd., New Delhi
2007
2
P. Sambasiva
Rao and D.
Bhaskar Rao
Techniques of
Teaching Psychology -
Sonali publications,
New Delhi 2006
3 S. K. Kochhar
Methods and
Techniques of
Teaching
- Sterling Publisher
Pvt. Ltd, New Delhi 2004
4.
K. Sampath, A.
Panner selvam
and S. Santhanam
Introduction to
Educational
Technology
4th revised
ed
Sterling Publisher
Pvt. Ltd 2000
5. S. Robinson Fundamentals of
Education Psychology 2nd Edition Ane Books Pvt. Ltd 2008
6. T.M. Srinivasan
Use of Computers and
Multimedia in
Education
- Aavisakar
publication, Jaipur 2002
7. K. Sundarrajan Internet -
Kannadhasan
publications,
Chennai
1998
Web References:
https://swayam.gov.in/nd2_ntr20_ed21/preview
Relationship Matrix for Course Outcomes, Programme Outcomes and Programme Specific
Outcomes:
Semester Code Title of the Course Hours Credits
I 20MPCH1CC3 TEACHING AND
LEARNING SKILLS
4 4
Course
Outcomes
(COs)
Programme Outcomes
(POs)
Programme Specific Outcomes
(PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1 PSO2 PSO3 PSO4 PSO5
CO1 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO2 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO3 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO4 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO5 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
Number of Matches= 44, Relationship is : High
Prepared by: Checked by:
Dr.K.Loganathan Dr.Syed Ali Badusha
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC4 Core – IV SYNTHETIC ORGANIC
CHEMISTRY 4 4 100 25 75
Course Outcomes: 1. Apply various concepts, applications and interpretation of NMR and mass spectroscopy
2. Solve structural elucidation of organic compounds by NMR spectroscopy
3. Appraise the principle of XRD in structure determination
4. Investigate special techniques used in synthetic methods
5. Design the idea of innovative routes to organic synthesis using reagents
UNIT - I
NMR Spectroscopy: 1H- NMR principles, chemical shift and its applications. Coupling constant and its
applications. Fourier transforms NMR – Second order spectra –Systems with chemical
exchange – Study of fluxional behavior of molecules. 13C- NMR spectroscopy – Basic theory of FT-NMR – Relaxation – Broad band
decoupling – Off resonance decoupling and chemical shift correlations (CH, CH2, CH3,
aromatic). Identification of structure based on NMR data. Application of Dept, 1H- 1H COSY,
NOESY in structure elucidation of organic compounds.
UNIT- II
Mass Spectroscopy:
Instrumentation – Resolution, base peak, isotopic peaks, metastable peak, parent peak
– determination and use of molecular formula, recognition of molecular ion peak – ionization
by EI, CI, FAB and ESI methods – Fragmentation – General rules –Pattern of fragmentation
for various classes of compounds – McLafferty rearrangement – Importance of metastable
peaks –Molecular fragmentations – Ion reactions.
X-ray diffraction studies:
Bragg’s equation, Experimental methods, structure determination.
UNIT - III
Special Techniques in synthetic methods:
Phase transfer catalysis, Micellar medium synthesis, polymer supported synthesis,
ionic liquids, microwave assisted synthesis, sonochemistry.
UNIT - IV
Important Reagents in organic synthesis:
Use of following reagents in organic synthesis and functional group transformations –
complex metal hydrides, Gilman’s reagent, lithium dim ethyl cuprate, LDA, DCC, 1,3 -
Dithane (reactivity umpolung). Merrifield resin, Peterson’s synthesis, Lawesson’s reagent.
Wilkinson’s catalyst, Bakeryeast., hypervalent organo iodine’s (introduction) and reagents
of non-transition metals – Zn, Cd, Sn and In.
UNIT – V
Reagents for Oxidation: Osmium tetroxide, Sharpless asymmetric epoxidation, Chromyl chloride, Ozone,
DDQ, Dioxiranes, Lead tetra acetate, Selenium dioxide, DMSO either with Ac2O or Oxalyl
chloride, Dess-Martin reagent. LDA, Phase transfer catalysis (PTC), Merrifield resin, Baker’s
yeast.
Reagents for Reduction: Catalytic hydrogenation and dehydrogenation, Reduction with LiAlH4, NaBH4,
Tritertiarylbutoxy aluminum hydride, NaCNBH3, Tributyltin hydride, Me3SiCN, Alkali
metals for reduction, Reductions with hydrazine’s.
Books for Reference: 1. Rusell S.Drago, Physical Methods in Chemistry, W.B.Saunders Company.
2. G.Aruldhas, Molecular structure and spectroscopy, second edition, PHI learning Pvt.
Ltd., New Delhi, 2008.
3. Jerry March – “Advanced organic chemistry reactions mechanism and sturcure”, 4th
Ed., (2006), Wiley India Pvt. Ltd.
4. F.A. Carey and R.J. Sundberg – “Advanced organic chemistry” Vol. I and II– 3rd Ed.,
(1984), Plenum Publications.
5. R.O.C. Norman – “Principles of Organic Synthesis” – 2nd Ed., (1986), Chapman and
Hall Publications, New York.
6. O.P. Agarwal – “Reactions and Reagents in Organic Chemistry”, 5th Ed., (2005), Goel
Publishing House, Meerut.
7. Robert M. Silverstein, Francis X. Webster, David Kiemle “Spectrometric Identification
of Organic Compounds”, John Wiley & sons (2005).
Web References:
https://nptel.ac.in/courses/102/103/102103044/ https://nptel.ac.in/courses/104/104/104104101/
Relationship Matrix for Course Outcomes, Programme Outcomes and Programme Specific
Outcomes:
Semester Code Title of the Course Hours Credits
I 20MPCH1CC4 SYNTHETIC ORGANIC
CHEMISTRY
4 4
Course
Outcomes
(COs)
Programme Outcomes
(POs)
Programme Specific Outcomes
(PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1 PSO2 PSO3 PSO4 PSO5
CO1
CO2
CO3
CO4
CO5
Number of Matches= 42, Relationship is : High
Prepared by: Checked by:
Dr. M. Seeni Mubarak
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC4 Core – IV CORROSION STUDIES 4 4 100 25 75
Course Outcomes
1. Identify oxidizing/reducing agents in chemical reaction.
2. become familiarized with electrochemical process involved in corrosion process
3. apply standard reduction potential data to determine the relative strength of
oxidizing/reducing agents.
4. get knowledge to control corrosion of metals and alloys by using inhibitors
5. Construct an electrochemical cell diagram, including identifying the anode, cathode,
direction of electron flow, sign of the electrodes, direction of ion flow in salt bridge,
from a redox reaction or from short hand cell notation.
Unit-I
Corrosion - Definition, causes and cost - consequence - Theories of corrosion -
Direct chemical attack, electrochemical theory and acid theory - Different forms of
corrosion- uniform, pitting, galvanic, crevice, stress, erosion, film forming, intergranular,
dealloying, exfoliation and fretting - factors influencing corrosion - Nature of the metal -
oxidation potential, over voltage, purity and passive character - Nature of the environment -
temperature, moisture, impurities, pH and conductance.
Unit-II
Electrochemical aspects of corrosion - activation polarization, exchange current,
current density, concentration polarization, corrosion potential, corrosion current, charge
transfer resistance, linear polarization resistance, fmax and double layer capacitance, phase
angle - applications of Nernst, Tafel and Butler - Volmer's equations- corrosion rate-
expressions for corrosion rate.
Unit-III
Corrosion monitoring techniques - non electrochemical methods - weight loss
measurements and gasometric method – electro chemical methods - potentiodynamic
polarization and A.C impedance spectroscopy – Determination of surface coverage –
Biocidal efficiency and its determination - methods of corrosion control - modification of
metal, modification of environment and change of metal environment potential.
Unit-IV
Corrosion inhibitors - Definition, need and importance - classification of inhibitors -
acid, alkaline, neutral inhibitors and green inhibitors- vapour phase inhibitors - Recent
classification - neutralizers, barrier layer formers and scavengers – Theories of inhibition of
corrosion - mode of actions of inhibitors - adsorption - electrostatic, physical and chemical -
adsorption isotherms - Langmuir and Temkin's - principle and applications – Biocidal
efficiencies.
Unit-V
Organic inhibitors - advantages – anodic and cathodic inhibitors- nitrogen, oxygen
and sulphur containing organic compounds - mechanism of inhibition - formation of a
physical barrier, reduction in metal reactivity and change in the electrical double layer
structure - correlation between adsorption and inhibition of corrosion.
References:
1. Advanced physical chemistry, J.N, Gurtu and A.Gurtu, Pragati publications,
8th revised edition, 2007.
2. Essential of physical chemistry, Bahl, Tuli and Arun bahl, S.Chand publications,
2004.
3. An introduction to electrochemistry, Samuel.Glasstone, Affiliated East-west
private limited, New Delhi.
Online Reference
1. https://swayam.gov.in/nd1_noc20_mm27/preview
Relationship Matrix for Course Outcomes, Programme Outcomes and Programme Specific
Outcomes:
Semester Code Title of the Course Hours Credits
I 20MPCH1CC4 CORROSION
STUDIES
4 4
Course
Outcomes
(COs)
Programme Outcomes
(POs)
Programme Specific Outcomes
(PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1 PSO2 PSO3 PSO4 PSO5
CO1 √ √ √ √ √ √ √ √ √
CO2 √ √ √ √ √ √ √
CO3 √ √ √ √ √ √ √ √ √
CO4 √ √ √ √ √ √ √ √
CO5 √ √ √ √ √ √ √ √ √ √
Number of Matches= 43, Relationship is : High
Prepared by: Checked by:
Dr. A. Jamal Abdul Jafar
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC4 Core – IV PHYTOCHEMICAL
TECHNIQUES 4 4 100 25 75
Course Outcomes
After completion of the course the students
1. will able to isolate and separate the phytochemical compounds using various
techniques.
2. will know about characteristics of the phytochemical compounds.
3. Will Apply the microbial techniques using various procedure.
4. Analyze the compounds using various spectral techniques.
5. Evaluate the Nanoparticles using various Nano techniques.
UNIT - I Phytochemical Analysis
Methods of separation - Isolation and identification - Qualitative and quantitative analysis
of phenolic compounds - Anthocyanins – Alkaloids - Flavonoids - Xanthones - Stibenes -
Terpenoids, Steroids- Tannins- Saponins- Carbohydrates - Poly Phenols -Amino acids.
UNIT - II Separation Techniques
Methods of Extraction - cold percolation method - soxhlet method - methods of isolation -
methods of separation.
Chromatography - Definition – Principle – Classification - Paper Chromatography -
Column Chromatography - Thin layer Chromatography - Gas Chromatography - High
performance Liquid Chromatography - Vacuum distillation - Crystallization techniques.
UNIT - III Microbial Techniques
Classification of plants - Nomenclature - Cells - Tissues - Structures and functions of
Cells and tissues - Primary metabolites - Secondary metabolites - Microorganism - Biological
activities - Microbial studies - techniques.
UNIT - IV Spectral Techniques
Spectroscopy - Principle - Classification - UV - VIS spectroscopy - IR spectroscopy-
Proton and carbon -13 NMR spectroscopy - FTIR - GC – MS, LC - MS - Mass spectroscopy
- Principle - Instrumentation and Applications.
UNIT - V Nano Techniques
Nano Particles - Classification of Bio synthesis Nano particles - Characterization -
Scanning Electron Microscopy (SEM) -Atomic Force Microscopy (AFM) - Transmission
Electron Microscopy (TEM) - Resolution and Scanning Transition Electron Microscopy
(STEM) - Scanning Tunneling Microscopy (STM) - Scanning Near field Optical Microscopy
(SNOM).
Reference Books:
1. Francis A.Carey, “Organic chemistry”, 5th edition, Tata McGraw Hill, New Delhi,
1993.
2. Graham Solomns T.W, “Organic chemistry”, Vol. I & II 5th edition, John Wiley &
Sons, New York, 1992.
3. O.P.Agarwal, “Organic chemistry” Reactions and Reagents. Published by Krishna
Prakashan media (P) Ltd. 2016.
4. Morrison and Boyd, “Organic chemistry”, Paramount Communications,2007
5. Atta-Ur-Rahman and M.I.Choudhary, New Trends in Natural Products chemistry,
Gordon & Breach Science Publishers, I Edn., 1998.
6. Principle of Nano Technology by Michael Wilson, Overseas press India (P.Ltd)
New Delhi-110002, 1st Edition 2005.
Mapping:
Semester Code Title of the Course Hours Credits
I 20MPCH1CC4 PHYTOCHEMICAL
TECHNIQUES
4 4
Course
Outcomes
(COs)
Programme Outcomes
(POs)
Programme Specific Outcomes
(PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1 PSO2 PSO3 PSO4 PSO5
CO1
CO2
CO3
CO4
CO5
Number of Matches= 34 Relationship is : Moderate
Prepared by: Checked by:
Dr. A. Zahir Hussain
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC4 Core – IV PLANT AND
ENVIRONMENTAL CHEMISTRY
4 4 100 25 75
Course outcome
After completion of the course students were able to
1. Check the water quality of sample
2. Create awareness to the public regarding water quality standard parameters.
3. Isolate and characterize the phytochemical present in plant sources.
4. Use the phytochemicals for drug synthesis.
5. To elucidate the structures of isolated compounds from plant source.
UNIT- I
Environment
Concept of environmental chemistry - components of environment- factors affecting
environment, segments of environment- formation of physical chemical and biological
weathering, composition of soil- process of soil formation. Physical and chemical properties
of Air, soil and water, Atmosphere composition- pressure and temperature changes of
troposphere, stratosphere, mesosphere and ionosphere.
UNIT- II
Analysis of Water Pollution
Objectives of analysis - Sampling techniques- parameter for analysis – color ,turbidity
- total solids - conductivity - acidity - alkalinity - hardness - chloride sulphate - fluoride
phosphate, nitrate, DO, BOD, COD and heavy metal analysis- Impact of cadmium,
chromium, copper, lead, zinc, manganese, mercury and arsenic- Prevention and control
measures.
UNIT- III
Spectroscopy technique
Laws of absorption – Beer Lambert’s law- Instrumentation and applications of
turbidimetry, nephelometry and colorimetery. AAS-principle, instrumentation and
applications. Atomic Emission spectroscopy – principle, instrumentation and applications. FT
–IR- theory and applications.
UNIT- IV
Phytochemical analysis
Introduction and plant chemicals, methods of extraction, isolation, separation and
identification- Soxlet method- principle - procedure - uses. Preliminary phytochemical
screening and detection of various plant constituents. Bioactive compounds and its biological
activities- Applications.
UNIT- V
Chromatography and separation Techniques
Definition, Types, column chromatography, HPLC, TLC. Principle - Experimental
techniques – Applications.. GC -MS, principle, technique and applications.
REFERENCES:
1. B. K. Sharma and H. Kaur, Water Pollution Krishna Prakashan Mandir, Meerut.
2. T. H.Y. Tebbut, Principles of Water Quality Control A. Butterworth-Heinemann
Cleaning our environment - a chemical perspective 2nd edition, American
Chemical Society.
3. J Shapiro Radiation Protection 4th Ed. Harvard University Press, London.
4. S K Banedee Environmental Chemistry Goel Publishing House, Meerut.
5. G. W. Ewing Instrumental Method of Chemical Analysis, McGraw- Hill, New
York.
6. H. Kaur - "Instrumental methods of Chemical Analysis", 6,j' edition, (2010),
Pragati prakasan Publications, Meerut.
7. Willard, Meenitt, Dean and Settle - "Instrumental Methods of Analysis", 7 th
Ed.,(2006), CBS Publishers.
8. B.K. Sharma - "Instrumental methods of Analysis", (2000), Goel Publications.
9. S.M. Khopkar, "Basic Concepts of Analytical Chemistry", Revised edition (2006)
Wiley Eastern Ltd.
10. R.A. Day and A.L. Underwood - "Quantitative Analysis", (1999), PrenticeHall of
India Pvt., Ltd., New Delhi.
11. H. Kaur - "Instrumental methods of Chemical Analysis", 6,j' edition, (2010),
Pragati prakasan Publications, Meerut.
12. Willard, Meenitt, Dean and Settle - "Instrumental Methods of Analysis", 7 th
Ed.,(2006), CBS Publishers
13. Principles of Instrumental Analysis by Donglas A. Skoog, James, J. Leary,
4th Edition.
14. Instrumental Methods of Chemical Analysis – B. K. Sharma - 9th Edition.
15. Instrumental Methods of Analysis – Hobert H. Willard, 7th Edition.
Online Course References
1. https://swayam.gov.in/nd2_cec19_bt03/preview
2. https://swayam.gov.in/nd1_noc19_bt17/preview
Relationship Matrix for Course Outcomes, Programme Outcomes and Programme
Specific Outcomes:
Semester Code Title of the Course Hours Credits
I 20MPCH1CC4 PLANT AND
ENVIRONMENTAL
CHEMISTRY
4 4
Course
Outcomes
(COs)
Programme Outcomes
(POs)
Programme Specific Outcomes
(PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1 PSO2 PSO3 PSO4 PSO5
CO1 √ √ √ √
CO2 √ √ √ √ √ √ √ √
CO3 √ √ √ √ √ √ √ √
CO4 √ √ √ √ √ √ √ √ √
CO5 √ √ √ √ √ √ √
Number of Matches= 36, Relationship is : High
Prepared by: Checked by:
Dr. J. Sirajudeen
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC4 Core – IV SYNTHETIC ORGANIC
CHEMISTRY 4 4 100 25 75
Course Outcomes: Learners will be able to
1. Investigate the purity of a reaction mixture by various chromatographic techniques
2. Formulate a reaction pathway for the target material by disconnection approach
3. Design and validate various reactions, reagents and solvents
4. Determine the structure of unknown molecular entity by X-ray diffraction and NMR
spectroscopic techniques
5. Solve and generate molecular structure by various spectroscopic techniques
UNIT-I 12 hours
Chromatography :
Principle-types- Thin Layer Chromatography-Principle, experimental techniques,
applications of TLC. Paper chromatography-principle, types, experimental techniques of
paper chromatography, applications. Column Chromatography-definition, principle types,
Experimental techniques – Characteristics of good adsorbent – developers – techniques of
separation – detectors, applications. HPLC- principle, experimental technique, applications.
UNIT-II 12 hours
Disconnection approach:
An introduction to Synthons and synthetic equivalents, disconnection approach,
functional group interconversions. One group C-X and two group disconnections in 1, 2, 1, 3
-,1,4- & 1,5 difunctional compounds , Retro- synthesis of Alkene ,acetylenes and aliphatic
nitro Alcohols and carbonyl compounds, amines , the importance of the order of events in
organic synthesis, chemoselectivity, regioselectivity. Diels Alder reaction, Michael addition
and Robinson annulation. Retro- synthesis of aromatic Heterocycles and 3, 4, 5 and 6
membered carbocyclic and heterocyclic rings. Reversal of polarity (Umpolung).
UNIT-III 12 hours
Application of the following in synthesis:
Application of following reagents in synthesis. Complex metal hydrides, lithium
dialkyl cuprate, lithium diisopropylamide(LDA) Dicyclohexylcarbodiimide(DCC), Trimethyl
silyl iodide, tributyltin hydride, peracids, lead tetra acetate, Diazomethane , phase transfer
catalyst, Selenium dioxide, DDQ, periodic acid, KMnO4, CrO4, MnO2 and OsO4. Solvents -
comparative study on solvents like protic, aprotic, acidic and basic
UNIT-IV 12 hours
X-ray diffraction:
Fundamentals of X-ray diffraction, theory of X-ray diffraction, diffraction of x-rays
by crystals, determination of crystal structure (powder as well as single crystals),
Instrumentation, determination of lattice parameters, X-ray intensity calculations and
application of X-rays.
2D NMR spectroscopy:
Basic principles of COSY, ROSY and NOESY.
UNIT-V 12 hours
Reactions and reactivity of phenol, resorcinol, pyridine, pyrimidine and active methylene
compound ( malonic acid, malonic ester and malono nitrile)
Combined Spectroscopic problems of IR, 1H NMR, 13C NMR and Mass spectroscopy.
Books for Reference: S.
No. Author Name Book Name Edition Publisher detail
Year
1 H. Kaur Instrumental methods of
chemical analysis 12th Edition
Pragati prakashan,
Meerut
2016
2 A. K. Srivastava
and P.C. Jain
Instrumental approach to
chemical analysis 4th Edition
S. Chand & Co.,
New Delhi 2009
3 Stuart Warren
Organic Synthesis:
The Disconnection
Approach
- John Wiley & Sons. New
York 2008
4. R.O.C. Norman Principle of organic
synthesis. 3th Edition Taylor & Francis Ltd 1993
5.
Carey, Francis
A., Sundberg,
Richard J.
Advanced Organic Chemistry. Part B: Reaction
and Synthesis.
5th Edition Springer US 2007
6. P.S.Kalsi Spectroscopy of Organic
Compounds 6th Edition
New Age International
Publishers. 2007
7.
Robert M.
Silverstein,
Francis X.
Webster,
David J.
Kiemle,
David L. Bryce
Spectrometric
Identification of Organic
Compounds
8th Edition John Wiley & sons, Inc. 2014
Web References:
https://nptel.ac.in/courses/102/103/102103044/ https://nptel.ac.in/courses/104/104/104104101/
Relationship Matrix for Course Outcomes, Programme Outcomes and Programme
Specific Outcomes:
Semester Code Title of the Course Hours Credits
I 20MPCH1CC4 SYNTHETIC
ORGANIC
CHEMISTRY
4 4
Course
Outcomes
(COs)
Programme Outcomes
(POs)
Programme Specific Outcomes
(PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1 PSO2 PSO3 PSO4 PSO5
CO1 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO2 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO3 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO4 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO5 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
Number of Matches= 44 , Relationship is : High
Prepared by: Checked by:
Dr. K. Loganathan
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC4 Core – IV CORROSION INHIBITORS 4 4 100 25 75
Course Outcomes:
Learners will be able to
1. Investigate the types and influencing factors of corrosion
2. Assess the electrochemical aspects of corrosion
3. Evaluate the corrosion rate by Corrosion monitoring techniques
4. Solve corrosion by inhibitors
5. Generate new organic corrosion inhibitors
UNIT-I 12 hours
Corrosion
Corrosion-Definition, causes and cost- Theories of corrosion-Direct chemical attack,
electrochemical theory and acid theory -Types of corrosion - uniform, pitting, galvanic,
crevice, stress, erosion, film forming, intergranular, dealloying, exfoliation and fretting -
factors influencing corrosion - Nature of the metal - oxidation potential, over voltage, purity
and passive character - Nature of the environment - temperature, moisture, impurities, pH and
conductance.
UNIT-II 12 hours
Electrochemical aspects of corrosion
Electrochemical aspects of corrosion- exchange current, current density, activation
polarization, concentration polarization, corrosion potential, corrosion current, charge transfer
resistance and double layer capacitance - applications of Nernst, Tafel and Butler - Volmer's
equations- expressions for corrosion rate.
UNIT-III 12
hours
Corrosion monitoring techniques
Non electrochemical methods - weight loss measurements and gasometric method – electro
chemical methods - potentiodynamic polarization and A.C impedance spectroscopy -
methods of corrosion control - modification of metal, modification of environment and
change of metal environment potential.
UNIT-IV 12
hours
Corrosion inhibitors Definition, need and importance - classification of inhibitors - acid, alkaline and neutral
inhibitors - vapour phase inhibitors - Recent classification - neutralizers, barrier layer formers
and scavengers - mode of actions of inhibitors - adsorption - electrostatic, physical and
chemical - adsorption isotherms - Langmuir and Temkin's - principle and applications.
UNIT-V 12 hours
Organic inhibitors
Organic inhibitors- advantages - nitrogen and sulphur containing organic compounds -
mechanism of inhibition - formation of a physical barrier, reduction in metal reactivity and
change in the electrical double layer structure - correlation between adsorption and inhibition
of corrosion.
Books for Reference: S.
No. Author Name Book Name Edition Publisher detail
Year
1 J. N. Gurtu and
A. Gurtu
Advanced physical
chemistry
8th revised
edition Pragati Publication
2007
2 Bahl, Tuli and
Arun Bahl
Essential of Physical
Chemistry 4th Edition S. Chand Publications 2004
3. Samuel
Glasstone
An introduction to
Electrochemistry -
Affiliated East-West Private
Limited, New Delhi 2000
Web References: https://swayam.gov.in/nd1_noc20_mm04/preview
Relationship Matrix for Course Outcomes, Programme Outcomes and Programme Specific
Outcomes:
Semester Code Title of the Course Hours Credits
I 20MPCH1CC4 CORROSION
INHIBITORS
4 4
Course
Outcomes
(COs)
Programme Outcomes
(POs)
Programme Specific Outcomes
(PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1 PSO2 PSO3 PSO4 PSO5
CO1 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO2 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO3 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO4 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO5 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
Number of Matches= 43 , Relationship is : High
Prepared by: Checked by:
Dr. M. Anwar Sathiq
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC4 Core – IV SYNTHETIC ORGANIC
CHEMISTRY 4 4 100 25 75
Course Outcomes: Learners will be able to
1. Investigate the purity of a reaction mixture by various chromatographic techniques
2. Formulate a reaction pathway for the target material by disconnection approach
3. Design and validate various reactions, reagents and solvents
4. Determine the structure of unknown molecular entity by X-ray diffraction and NMR
spectroscopic techniques
5. Solve and generate molecular structure by various spectroscopic techniques
UNIT-I 12 hours
Chromatography :
Principle-types- Thin Layer Chromatography-Principle, experimental techniques,
applications of TLC. Paper chromatography-principle, types, experimental techniques of
paper chromatography, applications. Column Chromatography-definition, principle types,
Experimental techniques – Characteristics of good adsorbent – developers – techniques of
separation – detectors, applications. HPLC- principle, experimental technique, applications.
UNIT-II 12 hours
Disconnection approach:
An introduction to Synthons and synthetic equivalents, disconnection approach,
functional group interconversions. One group C-X and two group disconnections in 1, 2, 1, 3
-,1,4- & 1,5 difunctional compounds , Retro- synthesis of Alkene ,acetylenes and aliphatic
nitro Alcohols and carbonyl compounds, amines , the importance of the order of events in
organic synthesis, chemoselectivity, regioselectivity. Diels Alder reaction, Michael addition
and Robinson annulation. Retro- synthesis of aromatic Heterocycles and 3, 4, 5 and 6
membered carbocyclic and heterocyclic rings. Reversal of polarity (Umpolung).
UNIT-III 12 hours
Application of the following in synthesis:
Application of following reagents in synthesis. Complex metal hydrides, lithium
dialkyl cuprate, lithium diisopropylamide(LDA) Dicyclohexylcarbodiimide(DCC), Trimethyl
silyl iodide, tributyltin hydride, peracids, lead tetra acetate, Diazomethane , phase transfer
catalyst, Selenium dioxide, DDQ, periodic acid, KMnO4, CrO4, MnO2 and OsO4. Solvents -
comparative study on solvents like protic, aprotic, acidic and basic
UNIT-IV 12 hours
X-ray diffraction:
Fundamentals of X-ray diffraction, theory of X-ray diffraction, diffraction of x-rays
by crystals, determination of crystal structure (powder as well as single crystals),
Instrumentation, determination of lattice parameters, X-ray intensity calculations and
application of X-rays.
2D NMR spectroscopy:
Basic principles of COSY, ROSY and NOESY.
UNIT-V 12 hours
Reactions and reactivity of phenol, resorcinol, pyridine, pyrimidine and active methylene
compound ( malonic acid, malonic ester and malono nitrile)
Combined Spectroscopic problems of IR, 1H NMR, 13C NMR and Mass spectroscopy.
Books for Reference: S.
No. Author Name Book Name Edition Publisher detail
Year
1 H. Kaur Instrumental methods of
chemical analysis 12th Edition
Pragati prakashan,
Meerut
2016
2 A. K. Srivastava
and P.C. Jain
Instrumental approach to
chemical analysis 4th Edition
S. Chand & Co.,
New Delhi 2009
3 Stuart Warren
Organic Synthesis:
The Disconnection
Approach
- John Wiley & Sons. New
York 2008
4. R.O.C. Norman Principle of organic
synthesis. 3th Edition Taylor & Francis Ltd 1993
5.
Carey, Francis
A., Sundberg,
Richard J.
Advanced Organic Chemistry. Part B: Reaction
and Synthesis.
5th Edition Springer US 2007
6. P.S.Kalsi Spectroscopy of Organic
Compounds 6th Edition
New Age International
Publishers. 2007
7.
Robert M.
Silverstein,
Francis X.
Webster,
David J.
Kiemle,
David L. Bryce
Spectrometric
Identification of Organic
Compounds
8th Edition John Wiley & sons, Inc. 2014
Web References:
https://nptel.ac.in/courses/102/103/102103044/ https://nptel.ac.in/courses/104/104/104104101/
Relationship Matrix for Course Outcomes, Programme Outcomes and Programme
Specific Outcomes:
Semester Code Title of the Course Hours Credits
I 20MPCH1CC4 SYNTHETIC
ORGANIC
CHEMISTRY
4 4
Course
Outcomes
(COs)
Programme Outcomes
(POs)
Programme Specific Outcomes
(PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1 PSO2 PSO3 PSO4 PSO5
CO1 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO2 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO3 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO4 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO5 ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
Number of Matches= 44 , Relationship is : High
Prepared by: Checked by:
Dr. M. Purushothaman
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC4 Core – IV PHYSICAL ORGANIC
CHEMISTRY 4 4 100 25 75
Course Outcomes: Learners will be able to
1. Investigate the reaction rate and explain the theories of reaction rate. 2. Criticise the thermodynamic parameters and different types of catalysis. 3. Apply thevarious methods of reaction mechanism and linear free energy
relationship by Hammett and Taft equation. 4. Generate molecular structure by IR,UV,1 H NMR, and Mass spectroscopic
techniques 5. Design the reactions using different oxidizing reagents and solve the error by
statistical method.
UNIT-I Chemical Kinetics 1.1 Chemical Kinetics: Rate and rate constant – Order , Molecularity of the reaction- factors affecting rate of reactions – Experimental Determination of order of the reaction – First order reaction , characteristics and Examples of first order reactions 1.2 :Temperature effect on reaction rate - Arrhenius rate equation, energy of activation and its significance,Theories of reaction rates – simple collision theory, Absolute Reaction Rate Theory (ARRT) to simple uni-molecular and bimolecular processes - Comparison of collision theory & ARRT UNIT-II Kinetics of Thermodynamics and Catalysis 2.1 Thermodynamic parameters: Enthalpy, Entropy ,Energy of activation and Gibbs functions – some useful thermodynamics relationships. Applications of thermodynamic parameters: The applications of thermodynamics to rate processes – properties of transition state – uses of activation parameters. 2.2 Catalysis: Catalyst, types of catalysts - homogeneous and heterogeneous catalysis- Enzyme catalysis – Mechanism of single substrate reactions –Michaeli’s –Menten law- Influence of pH and temperature UNIT-III Correlation of Structure with reactivity 3.1 Methods of determining reaction mechanism: Energy profile diagrams – thermodynamic control and kinetic control of organic reactions – Isotope effects – Kinetic and non – kinetic methods of determination of reaction mechanisms – Product analysis and its importance. 3.2 Correlation Analysis: Linear free energy relationships – Hammett Equation- significance of sigma and rho applications deviations and limitations – Taft Equation and application.
UNIT-IV Spectro – Analytical Methods, Kinetics of Solutions 4.1 Spectro – Analytical Methods: Theory of spectrophotometry and colorimetry – Classifications of methods of colour measurements – Instrumentation of photoelectric colorimeter and spectrophotometers – Experimental colorimetric determination of chromium compounds – Introduction of spectroscopy-- types – electromagnetic spectrum – Instrumentations of IR,UV, 1H NMR and Mass spectroscopy 4.2 Kinetics of Solutions :Factors influencing reaction rates in solution – Applications of ARRT to Solution kinetics, Effects of solvents, double sphere and single sphere model- Effects of ionic Strength. UNIT-V Oxidation Reactions and Error Analysis 5.1 Oxidation Reactions Oxidation of Alcohols to aldehydes and ketones- Chromium Reagents such as K2Cr2O7 / H2SO4(Jones reagent) – Pyridinium chloro chromate (Corey’s reagent ), CrO3- Pyridine (Collins reagent) Oxidation involving C-C bond cleavage using HIO4,cycloalkanones using CrO3,Oxidation of C=C usingNalO4 and OsO4 aromatic ring using RuO4 5.2Error Analysis: Definition of Accuracy- Precision –classifications of errors- significant figures and computations – Mean deviation - Normal distribution Comparison of results the number of parallel determinations – the value of statistics Books for Reference:
S. No.
Author Name Book Name Edition Publisher detail Year
1 Laidler Chemical Kinetics 3rd edition Tata Mc Graw Hill.Co. New Delhi
1984
2
Kuriacose and Rajaram
Kinetics and Mechanism of Chemical transformation
1st edition Macmillan & Co 1993
3 V. B.Putania
Chemical kinetics 1st edition Campus Books International New Delhi
2004
4 Neil . S. Isaacs
Physical Organic Chemistry
2nd edition Longman Scientific and technical, New York
1987
5 Jerry March
Advanced Organic chemistry, Reactions, Mechanism and structure
4th edition wiley India PVT Ltd 2006
6 John R. Dyer
Applications of Absorption Spectroscopy of Organic Compounds
3rd edition Prentice Hall of India, New Delhi
1984
7 G. M. Barrow Introduction to Molecular Spectroscopy
6th edition Tata Mc Graw Hill.Co. New Delhi
1993
8
C. N. Banwell and E. M. Mccash
Fundamentals of Molecular Spectroscopy
4th edition Tata, McGraw-Hill Publishing Company Limited, New Delhi
2009
9
J. N. Gurtu and R. Kapoor
Organic Reactions Reagents”
1st edition, Sultan chand Company PVT, Ltd
1988
10 O. P. Agarwal
Reactions and Reagents in Organic chemistry
5th edition, “,Goel Publishing House, Meerut
2005
11 H. Kaur
Instrumental methods of chemical analysis
6th edition , Pragati Prakasan, Meerut
2010
12 Willard ,Meritt, Dean and Settle
Instrumental Methods of Analysis
7th edition CBS Publishers 1983
13 B. K. Sharma
Instrumental Methods of Analysis
19th edition Goel Publications 2000
Web References: https://nptel.ac.in/courses/102/103/102103044/
Relationship Matrix for Course Outcomes, Programme Outcomes and Programme Specific Outcomes:
Semester Code Title of the Course Hours Credits
I 20MPCH1CC4 PHYSICAL ORGANIC CHEMISTRY
4 4
Course Outcomes
(COs)
Programme Outcomes (POs)
Programme Specific Outcomes (PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1
PSO2 PSO3
PSO4 PSO5
CO1 ✔ ✔ ✔ ✔ ✔ ✔
CO2 ✔ ✔ ✔ ✔ ✔
CO3 ✔ ✔ ✔
CO4 ✔ ✔ ✔ ✔ ✔ ✔ ✔
CO5 ✔ ✔ ✔ ✔ ✔
Number of Matches= 41, Relationship is : High
Prepared by: Checked by:
Dr. K. Periyasamy
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC4 Core – IV PHYTOCHEMISTRY 4 4 100 25 75
Course outcomes:
At the end of the course the learners could be able to
1. Understand about the phytochemicals.
2. Use the of medicinal plants for various diseases
3. Analyze the structure of various phytochemicals
4. Deduce new compounds in pharma industry
5. Summarize the new compounds in pharma industry.
UNIT‐ I
Introduction: An overview of Indian Medicine Ayuveda .Traditional medicine /
Ethnomedicine Classification, taxonomy and phytochemistry of Medicinal Plants.
Therapeutic potential of Medicinal plants ‐ A global perspective. Recent development of
some natural products.
UNIT‐ II
Secondary Metabolites
Definition, types (Alkaloids, Steroids, glycosides and flavonoids).Structure, Chemistry,
Biosynthesis, Metabolism and Regulation of Secondary Metabolites, Secondary metabolites
as plant therapeutics, Economic importance of Secondary products.
UNIT –III
Free radicals and Anti-oxidant Free radicals –Introduction, Modern theory of free radical, Oxidative Stress, Free radicals
Scavengers. Antioxidants‐Definition, property and biological significance, Antioxidants –
Enzymes and Vitamins. Antioxidants as markers for liver and kidney disease. Medicinal
plants as a source of Direct and Indirect antioxidant activity.
UNIT –IV
Methods of Extraction – Cold Percolation Method – Soxhlet Method – Methods of Isolation
– Methods of Separation.
Chromatography Principle and applications of Thin layer, Paper, Column, Gas and High
performance Liquid Chromatography.
Distillations – Steam, fractional, vacuum distillation and Crystallization Techniques.
UNIT‐ V
Phytochemical analysis, Biochemical methods, qualitative and quantitative analysis –
Separation procedures, Purification, and structural elucidation of secondary compounds of
therapeutic potential by Mass and Proton and Carbon-13 NMR Spectroscopy.
Reference:
1. Harborne JB, 1988, Phytochemical Methods: A Guide to Modern Techniques of Plant
Analysis, II Ed., London and New York, Chapman and Hall.
2. Furniss BS, Hannaford AJ, Smith PWG and Tatchell AR, 1989, Vogel’s Text book of
Practical Organic Chemistry, V Ed., Essex, England, ELBS with Longman.
3. Finar I.L. Organic Chemistry, Vol. 2. ELBS London.
4. Raphael Ikan, 1969, Natural Products: A Laboratory Guide, Jerusalem, Israel University
Press.
5. Jeffrey C, 1982, An Introduction Plant Taxonomy, II Ed., Cambridge, Cambridge
University Press.
6. William J and Sham M, 1976, Microorganisms, London, Mills and Boon Limited.
7. Ari Koskinen, 1993, Asymmetric Synthesis of Natural Products, Chichester, New York,
Brisbane, Toronto, Singapore, John Wiley and Sons.
8.Plant Biochemistry by Dey and J.B. Harborne
Relationship Matrix for Course Outcomes, Programme Outcomes and Programme Specific Outcomes :
Semester Code Title of the Course Hours Credits
I 20MPCH1CC4 PHYTOCHEMISTRY 4 4
Course Outcomes
(COs)
Programme Outcomes (POs)
Programme Specific Outcomes (PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1 PSO2 PSO3 PSO4 PSO5
CO1 √ √ √ √
CO2 √ √ √ √ √ √ √
CO3 √ √ √ √ √ √ √ √
CO4 √ √ √ √ √ √ √ √ √
CO5 √ √ √ √ √ √ √
Number of Matches= 35, Relationship is : High
Prepared by: Checked by:
Dr. J. MUNEER AHAMATH
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC4 Core – IV ENVIRONMENTAL
POLLUTION: WATER, AIR AND SOIL
4 4 100 25 75
OUTCOMES:
At the end of the course the learners could be able to
1. Understand about the environmental pollution
2. Know the importance of water quality parameters
3. Gain to get the knowledge of pollution control and adapt suitable methods
4. Treat the waste water by adapting suitable techniques
5. Aware the disease caused by pollutants
Unit-I
Introduction and Classification: Introduction-environmental science- Environmental
chemistry-Ecology-Definition-Ecosystem-Cycling of mineral elements and gases-
Phosphate cycle-Carbon cycle-Hydrogen cycle-Nitrogen cycle-Hydrological cycle-
Environmental segment-Pollution and its type: air pollution - Water pollution - Soil
pollution -Other type of pollution-and its effect and control-Remedial measures.
Unit II
Air pollution: Introduction - Source of air pollution - air pollutant - Classification and
effects of air pollutants-oxides of nitrogen, sulphur and carbon-acid rain-effects and control
–hydrogen sulphide - effects and control – carbon mono oxide – effects and control –
photochemical smog- effects and control –fly ash – effects and control – green house
effects – global warming – effects and control – ozone layer – ozone depletion –chloro
fluoro carbons – effects and control.
Unit III
Water pollution: Introduction – types of water – Water pollution – sources of water
pollution – water pollutants – classification – physical, chemical and biological – inorganic
pollutants and toxic metals – organic pollutants – radioactive pollutants in water –
pesticides and fertilizers – suspended particles – water quality- water quality index – ill
effects of water pollutants – fluorosis – water pollution control – water treatment – primary,
secondary and tertiary treatment – desalination- reverse osmosis – sewage and industrial
waste water treatment. Unit IV
Soil pollution: Introduction – type of soil –soil pollution - types – indicators of soil pollution –
plants as indicators of pollution - sources of soil pollution – fertilizers and pesticides –
radioactive pollutants – solids waters – soil sediments as pollutants – soil erosion –
treatment of soil pollutants –treatment of solid wastes – thermal methods – land filling –
composting – land protection – remedial measures for soil pollution.
Unit V
Analysis of pollutants: Introduction-analysis of water pollution – units – sampling –
devices and methods for sampling – measurement: Turbidimetry nephelometry -
Conductometry – analysis of water pollutants – units – sampling – devices and methods for
sampling – measurement : Atomic Absorption spectroscopy – titration – analysis of
different water quality parameters – BOD – COD analysis and monitoring of Pesticides,
carcinogens and industrial pollutants.
Suggested Readings:
1. B. K. Sharma and H. kaur, Environmental chemistry, Krishina Prakashan, Meerut, 1997
2. A.K. De, Environmental chemistry, Wiley Eastern Ltd., Meerut,1994
3. A.K. Mukherjee, Environmental pollution and Health Hazards causes and control,
Galgotia press, New Delhi, 1986.
4. N. Manivasakam, Physico-chemical examination of water, sewage and industrial
effluents, Pragati Prakashan Publ.Meerut, 1985.
5. B.K. Sharma - "Instrumental methods of Analysis", (2000), Goel Publications.
6. S.M. Khopkar, "Basic Concepts of Analytical Chemistry", revised edition (2006) Wiley
Eastern Ltd.
7. R.A. Day and A.L. Underwood - "Quantitative Analysis", (1999), Prentice Hall of India
Pvt., Ltd., New Delhi.
Relationship Matrix for Course Outcomes, Programme Outcomes and Programme
Specific Outcomes:
Semester I Code Title of the Course Hours Credits
I 20MPCH1CC4 Environmental Pollution:
Water, Air and Soil
4 4
Course
Outcomes
(COs)
Programme Outcomes (POs) Programme Specific Outcomes (PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1 PSO2 PSO3 PSO4 PSO5
CO1 √ √ √ √ √ √ √ √ √
CO2 √ √ √ √ √ √ √ √
CO3 √ √ √ √ √ √ √ √
CO4 √ √ √ √ √ √ √
CO5 √ √ √ √ √ √ √ √
Number of Matches= 40, Relationship is : High
Prepared by: Checked by:
Dr. R. Abdul vahith
Semester Code Course Title of the
Course Hours Credits
Max. marks
Internal marks
External marks
I 20MPCH1CC4 Core – IV CORROSION INHIBITORS 4 4 100 25 75
Outcomes
At the end of the course, the student has
1. acquired basic electrochemical knowledge to understand corrosion processes
2. become familiarized with electrochemical process involved in corrosion process
3. been trained in corrosion protection measures
4. get knowledge to control corrosion of metals and alloys by using inhibitors
5. apply Nernst equation and the Tafel equation to different electrochemical systems
Unit-I
Corrosion - Definition, Historical lessons - causes and cost- consequence -
Orthodontic wires-Types – Uses- Theories of corrosion-Direct chemical attack,
electrochemical theory and acid theory - Different forms of corrosion- uniform, pitting,
galvanic, crevice, stress, erosion, film forming, intergranular, dealloying, exfoliation and
fretting - factors influencing corrosion - Nature of the metal - oxidation potential, over
voltage, purity and passive character - Nature of the environment - temperature, moisture,
impurities, pH and conductance.
Unit-II
Electrochemical aspects of corrosion - current density, exchange current, activation
polarization, concentration polarization, corrosion potential, corrosion current, charge
transfer resistance, linear polarization resistance, phase angle, fmax and double layer
capacitance - applications of Nernst, Tafel and Butler - Volmer's equations- corrosion rate-
expressions for corrosion rate.
Unit-III
Corrosion monitoring techniques - non electrochemical methods - weight loss
measurements and gasometric method – electro chemical methods - potentiodynamic
polarization and A.C impedance spectroscopy – Determination of surface coverage –
Biocidal efficiency and its determination - methods of corrosion control - modification of
metal, modification of environment and change of metal environment potential.
Unit-IV
Corrosion inhibitors - Definition, need and importance - classification of inhibitors -
acid, alkaline, neutral inhibitors and green inhibitors- vapour phase inhibitors - Recent
classification - neutralizers, barrier layer formers and scavengers – Theories of inhibition of
corrosion - mode of actions of inhibitors - adsorption - electrostatic, physical and chemical -
adsorption isotherms - Langmuir and Temkin's - principle and applications – Biocidal
efficiencies – Determination of biocidal efficiency –CFU.
Unit-V
Organic inhibitors - advantages – anodic and cathodic inhibitors- nitrogen, oxygen
and sulphur containing organic compounds - mechanism of inhibition - formation of a
physical barrier, reduction in metal reactivity and change in the electrical double layer
structure - correlation between adsorption and inhibition of corrosion.
References:
4. Advanced physical chemistry, J.N, Gurtu and A.Gurtu, Pragati publications,
8th revised edition, 2007.
5. Essential of physical chemistry, Bahl, Tuli and Arun bahl, S.Chand publications,
2004.
6. An introduction to electrochemistry, Samuel.Glasstone, Affiliated East-west
private limited, New Delhi.
Online Reference
1. https://swayam.gov.in/nd1_noc20_mm27/preview
Relationship Matrix for Course Outcomes, Programme Outcomes and
Programme Specific Outcomes:
Semester Code Title of the Course Hours Credits
I 20MPCH1CC4 CORROSION
INHIBITORS
4 4
Course
Outcomes
(COs)
Programme Outcomes
(POs)
Programme Specific Outcomes
(PSOs)
PO1 PO2 PO3 PO4 PO5 PSO1 PSO2 PSO3 PSO4 PSO5
CO1 √ √ √ √ √ √ √ √
CO2 √ √ √ √ √ √ √
CO3 √ √ √ √ √ √ √ √
CO4 √ √ √ √ √ √ √ √
CO5 √ √ √ √ √ √ √ √
Number of Matches= 39, Relationship is : High
Prepared by: Checked by:
Dr. S. S. Syed Abuthahir