Lipids - dezazma.comdezazma.com/wp-content/uploads/2019/08/Lipids-1.pdf · Important in the...

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Lipids

Dr Hadi Ansarihadipour

References:

1. Molecular Cell Biology. Fifth Edition. Harvey Lodish. Copyright

2. Biochemistry. Lehninger. 4th Edition, 2005.

3. Wikipedia

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Cholesterol

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β-sitisterol

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saccharolipid

Structure of the saccharolipid

Kdo2-lipid A (a hexa-acylated

disaccharide of glucosamine

that is glycosylated with two

3-deoxy-D-manno-

octulosonic acid (Kdo)

residues).

Glucosamine residues in

blue, Kdo residues in

red, acyl chains in black

and phosphate groups in

green. dezazma.com

https://en.wikipedia.org/wiki/Glucosamine

https://en.wikipedia.org/wiki/3-Deoxy-D-manno-oct-2-ulosonic_acid

https://en.wikipedia.org/wiki/Acyl

https://en.wikipedia.org/wiki/Phosphate

The building block of isoprenoid alcohols dezazma.com

isoprenoid alcohols

H – [ CH2CCH3=CHCH2 ]n – OH

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Important in the acylation of:

1. Proteins

2. Carotenoids

3. fat-soluble vitamins: A, E and K

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Cardiology

1. coronary heart disease:

angina and myocardial infarction

2. congestive heart failure

3. high blood pressure

4. abnormal cholesterol levels

5. deep vein thrombosis and pulmonary

embolism

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https://en.wikipedia.org/wiki/Cardiology

https://en.wikipedia.org/wiki/Coronary_heart_disease

https://en.wikipedia.org/wiki/Angina_pectoris

https://en.wikipedia.org/wiki/Myocardial_infarction

https://en.wikipedia.org/wiki/Congestive_heart_failure

https://en.wikipedia.org/wiki/High_blood_pressure

https://en.wikipedia.org/wiki/Dyslipidemia

https://en.wikipedia.org/wiki/Deep_vein_thrombosis

https://en.wikipedia.org/wiki/Pulmonary_embolism

Endocrinology

1. diabetes mellitus

2. polycystic ovarian syndrome

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https://en.wikipedia.org/wiki/Endocrinology

https://en.wikipedia.org/wiki/Diabetes_mellitus

https://en.wikipedia.org/wiki/Polycystic_ovarian_syndrome

Reproductive medicine

1. menstrual disorders

2. infertility

3. complications during pregnancy

4. birth defects

5. intrauterine fetal death

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https://en.wikipedia.org/wiki/Reproductive_medicine

https://en.wikipedia.org/wiki/Menstruation

https://en.wikipedia.org/wiki/Infertility

https://en.wikipedia.org/wiki/Maternal_obesity

https://en.wikipedia.org/wiki/Birth_defects

https://en.wikipedia.org/wiki/Stillbirth

Neurology

1. stroke

2. migraines

3. carpal tunnel syndrome

4. meralgia paresthetica

5. dementia

6. idiopathic intracranial hypertension

7. multiple sclerosis

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https://en.wikipedia.org/wiki/Neurology

https://en.wikipedia.org/wiki/Stroke

https://en.wikipedia.org/wiki/Migraines

https://en.wikipedia.org/wiki/Carpal_tunnel_syndrome

https://en.wikipedia.org/wiki/Meralgia_paresthetica

https://en.wikipedia.org/wiki/Dementia

https://en.wikipedia.org/wiki/Idiopathic_intracranial_hypertension

https://en.wikipedia.org/wiki/Multiple_sclerosis

Psychiatry

1. depression in women

2. social stigmatization

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https://en.wikipedia.org/wiki/Psychiatry

https://en.wikipedia.org/wiki/Major_depressive_disorder

https://en.wikipedia.org/wiki/Social_stigma

Rheumatology and Orthopedics

1. Gout

2. poor mobility

3. osteoarthritis

4. low back pain

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https://en.wikipedia.org/wiki/Rheumatology

https://en.wikipedia.org/wiki/Orthopedics

https://en.wikipedia.org/wiki/Osteoarthritis

https://en.wikipedia.org/wiki/Low_back_pain

Dermatology

1. stretch marks

2. acanthosis nigricans

3. lymphedema

4. cellulitis

5. hirsutism

6. intertrigo

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https://en.wikipedia.org/wiki/Dermatology

https://en.wikipedia.org/wiki/Stretch_marks

https://en.wikipedia.org/wiki/Acanthosis_nigricans

https://en.wikipedia.org/wiki/Lymphedema

https://en.wikipedia.org/wiki/Cellulitis

https://en.wikipedia.org/wiki/Hirsutism

https://en.wikipedia.org/wiki/Intertrigo

Gastroenterology

1. gastroesophageal reflux disease

2. fatty liver disease

3. cholelithiasis (gallstones)

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https://en.wikipedia.org/wiki/Gastroenterology

https://en.wikipedia.org/wiki/Gastroesophageal_reflux_disease

https://en.wikipedia.org/wiki/Non-alcoholic_fatty_liver_disease

https://en.wikipedia.org/wiki/Cholelithiasis

Oncology

1. esophageal

2. colorectal

3. pancreatic

4. gallbladder

5. endometrial

6. kidney

7. Leukemia

8. Hepatocellular carcinoma

9. malignant melanoma

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https://en.wikipedia.org/wiki/Oncology

https://en.wikipedia.org/wiki/Esophageal_cancer

https://en.wikipedia.org/wiki/Colorectal_cancer

https://en.wikipedia.org/wiki/Pancreatic_cancer

https://en.wikipedia.org/wiki/Gallbladder_cancer

https://en.wikipedia.org/wiki/Endometrial_cancer

https://en.wikipedia.org/wiki/Renal_cell_carcinoma

https://en.wikipedia.org/wiki/Leukemia

https://en.wikipedia.org/wiki/Hepatocellular_carcinoma

https://en.wikipedia.org/wiki/Malignant_melanoma

Respirology

1. obstructive sleep apnea

2. obesity hypoventilation syndrome

3. asthma

4. increased complications during general

anaesthesia

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https://en.wikipedia.org/wiki/Respirology

https://en.wikipedia.org/wiki/Sleep_apnea

https://en.wikipedia.org/wiki/Obesity_hypoventilation_syndrome

https://en.wikipedia.org/wiki/Asthma

https://en.wikipedia.org/wiki/General_anaesthesia

Urology and Nephrology

1. erectile dysfunction

2. urinary incontinence

3. chronic renal failure

4. hypogonadism

5. buried penis

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https://en.wikipedia.org/wiki/Urology

https://en.wikipedia.org/wiki/Nephrology

https://en.wikipedia.org/wiki/Erectile_dysfunction

https://en.wikipedia.org/wiki/Urinary_incontinence

https://en.wikipedia.org/wiki/Chronic_renal_failure

https://en.wikipedia.org/wiki/Hypogonadism

https://en.wikipedia.org/wiki/Buried_penis

Lipids - dezazma.comdezazma.com/wp-content/uploads/2019/08/Lipids-1.pdf · Important in the...

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