Post on 18-Jan-2016
Leptospirosis is a bacterial disease related to genus Leptospira which cause septicemia, It is rare in cats but more common in dogs, cattle
Leptospirosis is a zoonotic disease (human).
NB: In man: it causes Weil’s
disease
Septicemia septicemia leads to petechial septicemia leads to petechial
hemorrhages and edemahemorrhages and edema on serous membranes (on serous membranes (pleurapleura ) )::may be seen in other organs as may be seen in other organs as
myocardiummyocardium ,,adrenal glandsadrenal glands,,
pancreaspancreas , ,gallbladdergallbladder and and lunglung
Pulmonary hemorrhage
A-Canine Leptospirosis:Pathognomonic Lesions:Acute leptospirosis:
Liver:
Macroscopic Picture: 1-The liver is enlarged and yellow
in color.2-Yellow m.m. due to icterus.
3-Peticheal hemorrhages on the pleura, pericardium and peritoneum.
IcterusIcterus
.
Microscopic Picture:1 -coagulative necrosis in hepatic cells.
2-Dissociation of the hepatic cells (individualization).
3-hemolytic jaundice with dilation of the bile canaliculi with yellow bile pigments.
4-Hemosiderosis are seen in the kupffer cells.
Organ : Liver.Stain : H&E.Micro : Dissociation and individualization hepatic cells.
B- Bovine leptospirosisSubacute and Chronic leptospirosis:Macroscopic Picture:
1-The kidneys are enlarged & atrophied (chronic).
2-Grayish-white spots throughout the cortex (white spotted kidney) andthe capsule is not easily detached.
3-Smooth or pitted surface with hemorrhage at the corticomedullaryjunction.
.
Microscopic Picture:1-Agggregations of lymphocytes
2-Extenssive coagulative necrosis.3-Fibrosis and cystic dilation of
some renal tubules in chronic stage.
4-Cellular and hyaline casts