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Gkjhmolkstry 18NOBOWAD SWKBHKSDOX

Srjtokb 

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Sroparoe abe prosobtoe gy

Larh Klmjtop Hray, L.E.Gaskh Loekhad Xhkobhos & H@ Uoahmor

Woforobho rosjurhos9

Jrnabkh hmolkstry Gkjhmolkstry‘^k`kpoeka Srjtokb-^k`kpoeka 

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Umo Alkbj Ahkes. Add prjtokbs aro pjdylorsjf alkbj ahkes, wmkhm aro gkfubhtkjbad jrnabkhhjlpjubes tmat hjbtakb gjtm ab alkbj nrjupabe a hargjxydato nrjup. Ekfforobhos kb tmo W

nrjups jf alkbj ahkes hauso ekfforobhos kb tmoprjportkos jf alkbj ahkes abe prjtokbs. Ywkttorkjbs. Umo prosobho jf gjtm alkbj

nrjups abe hargjxyd nrjups kb alkbj ahkesla`os kt pjsskgdo fjr alkbj ahkes tj oxkst kbsovorad kjbkh fjrls, kbhduekbn tmo fjrl jf azwkttorkjb. Umo zwkttorkjb ks a ekpjdar fjrl kbwmkhm tmo bot hmarno jb tmo kjb ks zorj.

Woahtkjb jf Alkbj Ahkes. Alkbj ahkes habubeornj roahtkjbs hmarahtorkstkh jf abyfubhtkjbad nrjup kb tmo ljdohudo. Uwjroahtkjbs jf klpjrtabho aro tmo roahtkjb jftwj hystokbo ljdohudos tj fjrl a ek sudfkeo,

abe tmo roahtkjb jf alkbj nrjups abehargjxydato nrjups jf ekfforobt ljdohudos tjfjrl poptkeo (alkeo) dkb`anos.

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8/13/2019 IVMS Intro to Biochemistry Lecture 13 -Protein

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Klpjrtabt Soptkeos. Ljro tmab 733poptkeos mavo goob smjwb tj go ossobtkad tjtmo prjpor fubhtkjbkbn jf tmo mulab gjey.Mjrljbos abe ob`opmadkbs aro aljbn tmopoptkeos fjr wmkhm fubhtkjbs mavo goobkeobtkfkoe.

Hmarahtorkstkhs jf Srjtokbs. Srjtokbs arodarno pjdylors jf alkbj ahkes. Ahkekh abegaskh prjportkos jf prjtokbs aro eotorlkboe gytmo ahkekh jr gaskh hmarahtor jf tmo W nrjupsjf tmo alkbj ahkes hjlprkskbn tmo prjtokb.Srjtokbs porfjrl bulorjus klpjrtabt

fubhtkjbs kb tmo gjey. Srjtokbs aro hdasskfkoestruhturaddy as fkgrjus jr ndjgudar. Umoy arohdasskfkoe jb tmo gasks jf hjlpjsktkjb assklpdo jr hjbiunatoe.

Umo Srklary Xtruhturo jf Srjtokbs. Umoprklary struhturo jf a prjtokb ks tmo soquobhojf alkbj ahkes kb tmo pjdylorkh hmakb. Umks

nkvos add prjtokbs ab keobtkhad gah`gjbo jfhargjb abe bktrjnob atjls mode tjnotmor gypoptkeo dkb`anos. Umo ekfforobho kb prjtokbs kstmo soquobho jf W nrjups attahmoe tj tmogah`gjbo.

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Umo Xohjbeary Xtruhturo jf Srjtokbs. Srjtokb hmakbs aro mode kb hmarahtorkstkh smaposhaddoe sohjbeary struhturos gy myerjnobgjbes. Uwj spohkfkh struhturos tmat mavo goob

keobtkfkoe aro tmo adpma-modkx abe tmo gota-pdoatoe smoot. Umo Uortkary Xtruhturo jf Srjtokbs. A tmkre

dovod jf hjlpdoxkty kb prjtokb struhturo rosudtsfrjl kbtorahtkjbs gotwoob tmo W nrjups jfprjtokb hmakbs. Umoso kbtorahtkjbs kbhdueoeksudfkeo grkenos, sadt grkenos, myerjnobgjbes, abe myerjpmjgkh attrahtkjbs.

Umo Quatorbary Xtruhturo jf Srjtokbs. Xjlo fubhtkjbad prjtokbs hjbskst jf twj jrljro pjdypoptkeo hmakbs mode tjnotmor gyfjrhos suhm as kjbkh attrahtkjbs, eksudfkeogrkenos, myerjnob gjbes, abe myerjpmjgkh

fjrhos. Umo arrabnolobt jf tmoso pjdypoptkeostj fjrl tmo fubhtkjbad prjtokb ks haddoe tmoquatorbary struhturo jf tmo prjtokb.

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Srjtokb Myerjdysks abeEobaturatkjb. Umo poptkeo (alkeo)dkb`anos jf poptkeos abe prjtokbs hab

go myerjdyzoe ubeor apprjprkatohjbektkjbs. Umks eostrjys tmo prklarystruhturo abe prjeuhos sladdorpoptkeos jr alkbj ahkes. Umohmarahtorkstkh sohjbeary, tortkary, abe

quatorbary struhturos jf prjtokbs habadsj go eksruptoe gy hortakb pmyskhadjr hmolkhad hjbektkjbs suhm asoxtrolo tolporaturos jr pM vaduos.Umo eksruptkjb jf tmoso struhturos kshaddoe eobaturatkjb, abe hausos tmoprjtokb tj gohjlo bjbfubhtkjbad abe,kb sjlo hasos, tj prohkpktato.

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Fjrlatkvo Assosslobt

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Uj hroato a prjtokb, alkbjahkes aro dkb`oe vka a(b)

 ZZZZ gjbe.alkeoahotadostor

otmorhargjxydkh

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alkeo

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Umo prjtokb assjhkatoewktm hjbbohtkvo tkssuo

suhm as tobejbs ks9 fkgrjnoblyjskbhjddanob

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hjddanob

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A prjtokb hab go eobaturoegy wmkhm jf tmo fjddjwkbn. 

ahkesgasosmoatadd jf tmo agjvo

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add jf tmo agjvo

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Fjr tmo oxalpdodkstoe kb Fknuro 7,wmat typo jfstruhturo ks

smjwb: prklarysohjbearytortkary

quatorbary

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sohjbeary

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Fjr tmo oxalpdo

dkstoe kb Fknuro 8,wmat typo jfstruhturo kssmjwb: 

prklarysohjbearytortkaryquartorbary

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Umo obeUmab` yju fjr yjur attobtkjb

Furtmor Xtuey9Gkjhmolkstry abe Hodd GkjdjnyHjddono jf Xakbt Goboekht abe Xakbt Ijmb's _bkvorskty - Gkjhmolkstry Jbdkbo Kbekaba _bkvorskty - Loekhad Gkjhmolkstry Sano LKU - Gkjdjny Myportoxtgjj` 

BDL - Gkjhmolkstry BDL - Ljdohudar Hodd Gkjdjny _bkvorskty jf _tam - BotGkjhmol