Ian Graham et al. European Heart Journal 2007;28:2375-414

Classes of recommendations

Ian Graham et al. European Heart Journal 2007;28:2375-414

Levels of evidence

Ian Graham et al. European Heart Journal 2007;28:2375-414

Ian Graham et al. European Heart Journal 2007;28:2375-414

Ian Graham et al. European Heart Journal 2007;28:2375-414

Ian Graham et al. European Heart Journal 2007;28:2375-414

All deaths from circulatory disease in EuropeAll ages - Year 2000 or circa

Ian Graham et al. European Heart Journal 2007;28:2375-414

Ian Graham et al. European Heart Journal 2007;28:2375-414

Ian Graham et al. European Heart Journal 2007;28:2375-414

Ian Graham et al. European Heart Journal 2007;28:2375-414

Ian Graham et al. European Heart Journal 2007;28:2375-414

Ian Graham et al. European Heart Journal 2007;28:2375-414

The relationship of total cholesterol (TC):HDL cholesterol ratio to 10-year fatal CVD events in men and women aged 60 years with and without risk

factors, based on a risk function derived from the SCORE project

Ian Graham et al. European Heart Journal 2007;28:2375-414

Impact of combinations of risk factors on risk

Ian Graham et al. European Heart Journal 2007;28:2375-414

Ian Graham et al. European Heart Journal 2007;28:2375-414

Advantages in using the SCORE risk chart

• Intuitive, easy to use tool• Takes account of the multifactorial nature of CVD• Estimates risk of all atherosclerotic CVD, not just CHD• Allows flexibility in management - if an ideal risk factor level

cannot be achieved, total risk can still be reduced by reducing other risk factors

• Allows a more objective assessment of risk over time • Establishes a common language of risk for clinicians• Shows how risk increases with age• The new relative risk chart helps to illustrate how a young person

with a low absolute risk may be at a substantially higher and reducible relative risk.

Ian Graham et al. European Heart Journal 2007;28:2375-414

Ian Graham et al. European Heart Journal 2007;28:2375-414

Ian Graham et al. European Heart Journal 2007;28:2375-414

SCORE chart: 10-year risk of fatal CVD in populations at high CVD risk based on the following risk factors: age, gender,

smoking, systolic blood pressure, and total cholesterol

Ian Graham et al. European Heart Journal 2007;28:2375-414

SCORE chart: 10-year risk of fatal CVD in populations at low CVD risk based on the following risk factors: age, gender,

smoking, systolic blood pressure, and total cholesterol

Ian Graham et al. European Heart Journal 2007;28:2375-414

SCORE chart: 10-year risk of fatal CVD in populations at high CVD risk based on the following risk factors: age, gender, smoking,

systolic blood pressure, and total cholesterol: HDL cholesterol ratio

Ian Graham et al. European Heart Journal 2007;28:2375-414

SCORE chart: 10-year risk of fatal CVD in populations at low CVD risk based on the following risk factors: age, gender, smoking,

systolic blood pressure, and total cholesterol: HDL cholesterol ratio

Ian Graham et al. European Heart Journal 2007;28:2375-414

Relative risk chart

Ian Graham et al. European Heart Journal 2007;28:2375-414