genomicsandhealth.org

GDC-DCFPilot

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genomicsandhealth.org

GenomicDataCommons–DataCommonsFramework

●  NCIGenomicDataCommonsstarted2014●  3NCICloudPilots(nowNCICloudResources)2015●  TheseprojectswillbeintegratedwiththeDataCommons

FrameworkandwillsharecommonstandardsandAPIs.●  OrganizaKonsinclude:UniversityofChicago,Broad,Seven

BridgesGenomics&InsKtuteforSystemsBiology(morecoming)●  Mission:Weareworkingtogethertomakeiteasiertodevelop

andoperatelargescaledatacommonsanddataecosystemsforbiomedicalresearch.

●  IniKalfocusiscancergenomics.2

genomicsandhealth.org

NCIGenomicDataCommons• Launchedin2016withover4PBofdata.Nowhasover10PBofdata.

• JointprojectwithOICR.

• Usedby1500-2000+usersperday.

• Baseduponanopensourceso\warestackthatcanbeusedtobuildotherdatacommons.

*See: NCI Genomic Data Commons: Grossman, Robert L., et al. "Toward a shared vision for cancer genomic data." New England Journal of Medicine 375.12 (2016): 1109-1112.

genomicsandhealth.org

NCI Genomic Data Commons NCI & Third Party Cloud Resources & Apps

analyze explore & access Explore and access

access

Genomic Data Commons – DCF Open Data Sharing Ecosystem

data peering

Bionimbus

Third Party Data Commons

We all have open source stacks: we have collaborated on APIs and competed on implementations for the past 3 years.

genomicsandhealth.org

CommonsAlliance

TheCommonsAllianceisaneffortsothatGDC/DFC,AllofUs,andtheHumanCellAtlascandevelopcommonstandardsandAPIs.

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genomicsandhealth.org

GDC-DCFGA4GHEngagement

●  CurrentGA4GHworkstreamsengagement:o  Largescalegenomicso  Cloudo  DatauseandresearcherIDs(previouslyDataAccess)

●  WehavehadlimitedinteracKonwithGA4GHunKltherecentre-organizaKon.

●  Ourprojectgoalistoconvergeonthesmallestnumberofstandardssowecaninteroperatewithsimilarlargescaledatacommonsandcloud-basedanalysissystems.

●  WehavelessinterestinmovingtonewunimplementedAPIs.

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genomicsandhealth.org

GDC/DataCommonsFramework

Q&A

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