Post on 01-Jun-2020
Page 204 of 250
8. BIBILIOGRAPHY
� Afaf I, Abuelgasim S, Nuha HS, Mohammed AH. (2008).
Hepatoprotective effect of Lepidium sativum against carbontetrachloride
induced damage in rats. Res J Animal Veterinary Sci, 3: 20-23.
� Agarwal AK and Mehendale JK. (1983). Potentiation of carbon
tetrachloride hepato toxicity and lethality by chlordecone in female rats.
Toxicology, 26: 231-42.
� Agarwal M, Srivastava V, Saxena KK and Kumar A. (2006).
Hepatoprotective activity of Beta vulgaris against CCl4 induced hepatic
injury in rats. Fitoterapia, 77(2): 91-93.
� Ahmed B, Alam T, Varshney M and Khan A. (2002). Hepatoprotective
activity of two plants belonging to the apiaceae and the euphoribiaceae
family. J. Ethnopharmacol., 79(3): 313-316.
� Amin A, Lotfy M, Shafiullah M and Adeghate E. (2006), The protective
effect of Tribulus terrestris in diabetes. Annals of the New York Academy
of Sciences, 1084: 391-401.
� Arulkumaran KS, Rajasekaran A, Ramasamy A, Jegadeesan M, Kavimani
S, Somasundaram A. (2009). Cassia roxburghii seeds protect liver against
toxic effects of ethanol and carbontetrachloride in rats. Int J PharmTech
Res., 1(2): 273-246.
� Asha VV, Akhila S, Wills PJ and Subrammaniam A. (2004). Further
studies on the antihepatotoxic activity of Phyllanthus maderaspatensis, J
Ethnopharmacol., 92(1): 67-70.
Page 205 of 250
� Avadhoot Y and Rana AC. (1991). Hepatoprotective effect of Vitex
negundo against carbon tetrachloride induced liver damage. Arch. Pharm.
Res., 14(1): 96-98.
� Avijeet J, Manish S, Lokesh D, Anurekha J, Rout SP, Gupta VB and
Krishna KL. (2008). Antioxidant and hepatoprotective activity of
ethanolic and aqueous extracts of Momordica dioica leaves. J
Ethnopharmacol., 115(1): 61-66.
� Badam L, Deolankar RP, Rojatkar SR, Nagsampgi BA and Wagh UV.
(1988). In-vitro antimalarial activity of medicinal plants of India. Journal
of Medical Research, 87: 379-383.
� Balakrishnan BR, Sangameswaran B and Bhaskar VH. (2010). Effect of
methanol extract of Cascuta reflexa aerial parts on hepatotoxicity induced
by antitubercular drugs in rats. Inter. J. of Applied Research in Natural
Prod., 3(1): 18-22.
� Balakrishnan N, Balasubaramaniam A, Sangameswarn B and Bhaskar
VH. (2011). Hepatoprotective activity of two Indian medicinal plants
from western ghats, TamilNandu. J Nat Pharm, 2(2): 92-98.
� Balasubramaniyan V, Kalaivani SJ and Nalini N. (2003). Role of leptin
on alcohol induced oxidative stress in swiss mice. Pharmaco Res., 47:
211-216.
� Bardhan P, Sharma SK and Garg NK. (1985). In-vitro effect of an
ayurvedic liver remedy on hepatic enzymes in carbontetrachloride treated
rats. Ind J Med Res., 82: 359 364.
Page 206 of 250
� Bhanwra S, Singh J and Khosla P. (2000). Effect of Azadirachta indica
leaf aqueous extract on paracetamol induced liver damage in rats. Ind. J.
Physiol and Pharmacol., 44(1): 64-68.
� Bhaskar VH and Balakrishnan N. (2009). Hepatoprotective activity of
Laticiferous plant species (Pergularia daemia and Carissa carandas)
from western ghats, Tamil Nandu, India. Inter J Health Res., 2(2): 163-
170.
� Bhattacharya D, Pandit S, Mukherjee R, Das N, and Sur TK. (2003).
Hepatoprotective effect of Himolive, a polyherbal formulation in rats.
Indian J Physiol Pharmacol., 47(4): 435-440.
� Bhattacharyya D, Pandit S, Jana U, Sen S and Sur TK. (2005).
Hepatoprotective activity of Adhatoda vasica aqueous leaf extract on D
galactosamine – induced liver damage in rats. Fitoterapia, 76(2): 223.
� Boots AW, Haenen GR and Bast A. (2008). Health effects of quercetin:
from antioxidant to nutraceutical. Eur J Pharmacol, 585: 325-337.
� Boyle SP, Dobson VL, Duthie SJ, Hinselwood DC, Kyle JA and
Collins AR. (2000). Bioavailability and efficiency of rutin as
an antioxidant: a human supplementation study. Eur J Clin Nutr,
54:774-782
� Cameron GR, Thomas JC and Karunarathe WAE. (1936). The pathogenesis
of liver injury in carbon tetrachloride and ethanol poisoning. J. Path. Bact.,
41: 297.
Page 207 of 250
� Chadha YR. (1985). The Wealth of India: Raw Materials (Vol 1). In:
Adina Cordifolia, National Institute of Science Communication and
Information Resources (CSIR) publication, New Delhi, 82-84.
� Chang Chi H, Hsun Lang F and Wen Chuan L. (2008). Inhibitory effect
of Solanum nigrum on thioacetamide induced liver fibrosis in mice. J
Ethnopharmacol., 119: 117-121.
� Chattopadhyay RR. (2003). Possible mechanism of hepatoprotective
activity of Azadirachta indica leaf extract, Part II. J Ethonopharmacol.,
89(2 3): 217-219.
� Chitravanshi VC, Singh AP, Ghoshal S, Prasad BNK, Srivastava V and
Tandon J S. (1992). Therapeutic action of Nyctanthes arbor tristis against
caecal amoebiasis of rat. Inter J Pharmacog., 30: 71-75.
� Chopra RN and Chopra IC. (2006b). Indigenous Drugs of India, In: Adina
Cordifolia, Academic Publishers, Kolktta, India, 576.
� Citoglu GS, Dulger H, Ugras S and Sever B. (2004). Hepatoprotective
and anti inflammatory activities of Ballota glandulosissima. J
Ethnopharmacol., 95(2-3): 143-149.
� Cotran and Robbins. (2004). Basic Pathology, Saunders, the Curtis center,
Philadelphia Pennsylvania, 7: 614.
� CPCSEA. (2003). CPCSEA guidelines for laboratory animal facility.
Indian Journal of Pharmacology, 35: 257-274.
� D'Amour FF, Blood FR and Belden DA. (1965). The manual for
laboratory work in mammalian physiology. The University of Chicago
Press, Chicago, 126-128.
Page 208 of 250
� Das S and Sasmal D. (2002). Studies of certain pharmacological activities
of the flowers and seeds of Nyctanthes arbor tristis. Indian J.
Pharmacology, 35: 194-201.
� Davidso. (1999). Principle and practice of medicine, Churchill
Livingstone Elsevier Science Ltd, 19: 838-878.
� Dawkins MJR. (1963). Carbon tetrachloride poisoning in the liver of the
new born rat. J. Path. Bact, 85: 189.
� Deshmukh RD, Pokharkar RD, Takate SB, and Gite VN. (2007).
Amelioration of CCl4 induced hepatosuppression by Nyctanthes
arbortristis leaves in wistar albino rats. Pharmacologyonline,1: 203-208.
� Devi PK, Sreepriya M, Balakrishna K and Devaki T. (2004). Protective
effect of Premna tomentosa extract on membrane bound phosphatases and
inorganic cations transport in acetaminophen induced hepatotoxicity rats.
J Ethnopharmacol., 93(2 3): 371-375.
� Beshbishy HA. (2005). Hepatoprotective effect of green tea (Camellia
sinensis) extract against tamoxifen induced liver injury in rats. J Biochem
Mol Biol., 38(5): 563-570.
� Fan S and Weng CF. (2005). Co-administration of cyclosporine-A,
alleviates ethanol induced liver injury. World J Gastroenterol., 11(10): 1411-
1419.
� Farasworth NR and Pezzuto JM. (1983). Rational approaches to the
development of plant derived drugs in proceeding of the 2nd national
symposium on The Pharmacology and Chemistry of natural products,
Joaopessoa, Brazil, 3-5.
Page 209 of 250
� Farell GC. (1991). “Drug induced Liver Disease.” Current Hepat., 11: 95-
110.
� Farnsworth NR. (1966). Biological and phytochemical screening of
plants. J Pharmaceut Sci., 55(3): 225-276.
� Festa F, Aglitti T, Duranti G, Ricordy R, Perticone P and Cozzi R. (2001).
Strong antioxidant activity of ellagic acid in mammalian cells in vitro
revealed by the comet assay. Anticancer Res, 21: 3903-3908.
� Fleurentin J, Hoefler C, Lexa A, Mortier F and Pelt JM. (1986). Anisotes
trisulcus: Two traditional medicinal plants or hepatoprotective properties
of Crepis rueppellii. J Ethnopharmacol., 16(1): 105-111.
� Gennavo AR and Remington. (2000). “The science and practice of
pharmacy.” Philadelphia: Lipincott Williams and Wilkins, 20, 1088-1090.
� Germano MP, Angelo V, Sanogo R, Catania S, Alma RDe, Pasquale R
and Bisignano G. (2005). Hepatoprotective and antibacterial effects of
extracts from Trichilia emetica vahl. (Meliaceae). J Ethnopharmaco., 4
(1-2): 227-232.
� Ghadi PS. (2000). Disorders of Liver: Pathophysiology for pharmacy. 2nd
ed. Nashik: Career publications, 106-8 and 125-30.
� Ghosh T. (2007). Hepatoprotective activity of Bacopa monnieri against
ethanol induced toxicity in rat. Phcog.net., 3(10): 95-100.
� Gilani AH and Hussain K. (1995). Preventive and curative effect of
Artemisia absinthium on acetaminophen and CCl4 induced hepatotoxicity.
J Pharmacol., 26(2): 309-315.
Page 210 of 250
� Gilani AH, Yaeesh S, Jamal Q and Ghayur MN. (2005). Hepatoprotective
activity of aqueous – methanol extract of Artemisia vulgaris. Phytother
Res., 19(2): 170-172.
� Gothoskar SV and Ranadive KJ. (1971). Anticancer screening of SAN
AB; an extract of marking nut Semicarpus anacardium. Ind J Exp Bio.,
9(3): 372–375.
� Govindarajan R, Vijayakumar M, Rao CV, Shirwaikar A,
Mehrotra S and Pushpangadan P. (2004). Healing potential of
Anogeissus latifolia for dermal wounds in rats. Acta Pharm, 54: 331-338.
� Govindarajan R, Vijayakumar M, Singh M, Rao ChV, Shirwaikar A,
Rawat AK and Pushpangadan P. (2006). Antiulcer and antimicrobial
activity of Anogeissus latifolia. J Ethnopharmacol, 106: 57-61.
� Grahamesmith DG and Azonson JK. (1984). The drug therapy of gastro
intestinal, hepatic and biliary disorders Chaper 23 In: Oxford Textbook of
Clinical Pharmacology and Drug Therapy, Oxford University Press,
Oxford, (1): 383-385.
� Gujrati V, Patel N, Rao NV, Nandakumar K, Gouda TS and Shalam
S. (2007). Hepatoprotective activity of alcoholic and aqueous extracts
of leaves of Tylophora indica in rats. Ind J. Pharmacol., 39 (1): 43-47.
� Gupta P, Bajpai SK, Chadra K, Singh KL and Tandon JS. (2005).
Antiviral profile of Nyctanthes arbortristis against encephalitis causing
viruses. Indian J Exp. Biol., 43(12): 1156-1160.
� Gupta PP, Srimal RC and Tandon JS. (1993). Antiallergic activity of
some traditional Indian medicinal plants. Inter J Pharmacog., 31: 15-18.
Page 211 of 250
� Hajimehdipoor H, Sadeghi Z, Elmi S, Elmi A, Ghazi Khansari M,
Amanzadeh Y and Sadat SE. (2006). Protective effects of Swertia
longifolia and its active compound, swerchirin, on paracetamol induced
hepatotoxicity in mice. J Pharmacol., 58(2): 277-280.
� Handa SS and Kapoor VK. (2005). A Text Book of Pharmacognosy. 2nd
ed., Delhi, Balaji offset Printers, 9-10.
� Handa SS and Sharma A. (1990). Hepatoprotective activity of
Andrographolide from Andrographis paniculata against carbon
tetrachloride. Ind. J. Med. Res., 92: 276-92.
� Handa SS, Sharma A and Chakraborti KK. (1986). Natural products and
plants as liver protecting drugs. Fitoterapia, 57(5): 307-352.
� Haque R, Mondal S, Sinha S, Ghose MR, Sinhal P and Gupta S. (2011).
Hepatoprotective activity of Clerodendron inerme against paracetamol
induced hepatic injury in rats for pharmaceutical product. Inte. J. of Drug
Dev and Res., 3 (1): 118-126.
� Hardman JG and Limbird LE. (2001). Ehanol Chapter 18 In: Goodman
and Gilman’s The Pharmacological basis of Therapeutics, 10th ed,
McGraw – Hill Medical Publishing Division, 434.
� Harshmohan A. (2000). Text book of pathology, 4th ed, Jaypee brothers
Medical Publishers (P) Ltd, New Delhi, 599 and 602,603.
� Harshmohan A. (2002). The liver, biliary tract and exocrine pancreas.
In: Text book of pathology, 4th Ed, Jaypee Brothers Medical Publishers
(P) Ltd. New Delhi. 4: 569-630.
Page 212 of 250
� Hemieda FA, Abdel HSK and Elnga MA. (2005). Biochemical and
histological studies on H2 receptor antagonist ranitidine induced
hepatotoxicity in rats. Ind J Exp Biol., 43(9): 782-5.
� Hoefler C, Fleurentin J, Mortier F, Pelt JM and Guillemain J. (1987).
Comparative choleretic and hepatoprotective properties of young sprouts
and total plant extracts of Rosmarinus officinalis in rats. J
Ethnopharmacol., 19(2): 133-143.
� Hui ML, Hsien CT, Chau JW, Jin L, Chia WL and Fen PC. (2008).
Hepatoprotective effects of Solanum nigrum Linn extract against CCl4
iduced oxidative damage in rats. Chemico Biol Inter., 171: 283-293.
� Ira TM, Christopher D, Gove RD, Hughes lG, McFarlane and Williams R.
(1995). Protective effects of Osbeckia octandra against galactosamine and
tert butyl hydroperoxide induced hepatocyte damage. J Ethnopharmacol.,
49(2-1): 69-76.
� Ishak KG. (1982). The liver, “Pathology of Drug Induced and Toxic
Disease.” Riddell RH, New York: Churchill Livingstone, 459.
� Jafri MA, Subhani M, Jalis J, Kalim and Singh S. (1999).
Hepatoprotective activity of leaves of Cassia occidentails against
paracetamol and ethyl alcohol intoxication in rats. J Ethnopharmacol.,
66(3): 355-361.
� Janbaz KH, Saeed SA and Gilani AH. (2002). Protective effect of rutin
on paracetamol and CCl4-induced hepatotoxicity in rodents. Fitoterapia,
73: 557-563.
Page 213 of 250
� Jin YS, Heo SI, Lee MJ, Rhee HI and Wang MH. (2005). Free radical
scavenging and hepatoprotective actions of Quercus aliena acorn extract
against CCl4 induced liver. Free Radical Res., 39(12): 1351-1358.
� Jung SH, Lee YS, Lim SS, Lee S, Shin KH and Kim YS. (2004).
Antioxidant activities of isoflavones from the rhizomes of Belamcanda
chinensis on carbon tetrachloride induced hepatic injury in rats. Arch.
Pharma Res., 27(2): 184-188.
� Kannan M, Singh R, Kumar A, Jegatheswari P and Subburayalu S. (2007)
Studies on immuno-bioactivites of Nyctanthes arbortristis (Oleaceae).
African J Micro. Resc, 1(6): 88-91.
� Kapur V, Pillai KK, Hussain SZ and Balani DK. (1994).
Hepatoprotective activity of Jigrine on liver damage caused by alcohol
carbon tetrachloride and paracetamol in rats. Ind. J. Pharmacol., 26, 35-
40.
� Khandelwal KR. (2004). Practical Pharmacognosy, In: Preelimary
Phytochemical screening, In: Evauation, Nirali Prakashan, Pune, India,
149-153 and 157-159.
� Khatune NA, Mosaddik MA and Haque ME. (2001). Antibacterial
activity and cytotoxicity of Nyctanthes arbortristis flowers, Fitot., 72:
412-414.
� Kind PRN and King EJ. (1954). Estimation of plasma phosphates by
determination of hydrolysed phenol with antipyrine. J. Clin. Pathol., 322-
30.
Page 214 of 250
� Kirchain WR and Gill MA. (1999). “Drug Induced Liver Disease”,
Pharmaco therapy a pathophysiological approach. London Appleton and
Lange, 4: 628-636.
� Klaassen CD and Plaa GL. (1968). Effect of CCl4 on the metabolism,
storage and excretion of sulfobromophthalein. Toxicol. Appl. Pharmacol,
12: 132-9.
� Kokate CK and Gokhale SB. (2008). Practical Pharmacognosy (12th ed).
In: Physical and chemical testes for evauation of crude drugs, Nirali
Prakashan, Pune, India, 14-19, 107-111 and 121.
� Kokate CK, Purohit AP and Gokhale SB. (2005). Pharmacognosy (31st
ed). In: Traditinal and Alternative System of Medicin, Nirali Prakshan,
Pune, India, 4-5.
� Krishna MG, Pallavi E, Ravi KB, Ramesh M and Venkatesh S. (2007).
Hepatoprotective activity of Ficus carica leaf extract against carbon
tetrachloride induced hepatotoxicity in rats. DARU., 15(3): 162-167.
� Kukongviriyapan V, Janyacharoen T, Kukongviriyapan U,
Laupattarakasaem P, Kanokmedhakul S and Chantaranothai P. (2003).
Hepatoprotective and antioxidant activities of Tetracera loureiri. Phytother
Res,17:717-721
� Kulkarni GT. (2005). Herbal formulation development. Abstract GL12,
National seminar on emerging trends in ethnopharmacology, bagalkot. 12th
13th Nov.
� Kumar G, Banu GS, Pappa PV, Sundrarajan M and Pandian MR. (2004).
Hepatoprotective activity of Trianthema portulacastrum against
Page 215 of 250
paracetamol and thioacetamide intoxication in albino rats. J
Ethnopharmacol., 92(1): 37-40.
� Kuruvilla A. (1999). Herbal formulations as pharmacotherapeutic
agents. J Ethnopharmacol., 66(3): 355-61.
� Lal J, Chandra S, Raviprakash V and Sabir M. (1976). In-vitro
anthelmintic action of some indigenous medicinal plants on Ascaridia
Galli worms. Indian Journal of Physiology and Pharmacology, 20: 64-68.
� Laurance DR, Bennett PN and Brown MJ. (1997). Clinical Pharmacology.
Edinburg, Churchill Livingstone, 8: 589-590.
� Lowry OH, Rosebrough NJ, Farr AL and Randall RJ. (1951). Protein
measurement with the Folin phenol reagent, J Biol Chem., 193: 265-275.
� Lutterodt GD. (1988a). Oxytocic effect of an extract from Sida
veronicaefolia. Journal of Ethanopharmacol., 23(1): 27-37.
� Lutterodt GD. (1988b). Abortifacient properties of an extract from Sida
Veronicaefolia. Journal of Ethnopharmacology, 23(2-3): 313-322.
� Madani H, Talebolhosseini M, Asgary S and Nader GH. (2008).
Hepatoprotective activity of Silybum marianum and Cichorium intybus
against thioacetamide in rat. Pak J Nutrition., 7(1): 172-176.
� Maheswari C, Maryammal R and Venkatanarayanan R. Hepatoprotective
activity of “Orthosiphon stamineus” on lver damage caused by
paracetamol in rats. Jordan J Biological Sciences., 1(3): 105-108.
Page 216 of 250
� Mahida Yogesh and Mohan JSS. (2007). Screening of plant for their
potential antibactirial activity against staphylococcus and salmonella spp.
Natural Product Radiance, 1: 302-305.
� Manoj R, Bhandarkar H and Khan A. (2004). Antihepatotoxic effect of
Nymphaea stellata in rats. J. Ethnopharmacol., 91(1): 61-64.
� Mantena SK, Mutalik S, Srinivasa H, Subramanian GS, Prabhakar KR,
Reddy KR, Srinivasan KK and Unnikrishnan MK. (2005). Antiallergic,
antipyretic, hypoglycemic and hepatoprotective effects of aqueous extract
of Coronopus didymus. Biol. Pharm. Bull., 28(3): 468-472.
� Marina N, Abdul MM, Joydev KK, Sitesh CB, Farida B and Bidyut KD.
(2009). Protective effects of Flacourtia indica aerial parts extracts against
paracetamol‐induced hepatotoxiciy in rats. J Taibah University for Sci., 2:
1-6.
� Matsuda H, Morikawa T, Xu F, Ninomiya K and Yoshikawa M. (2004).
New isoflavones and pterocarpane with hepatoprotective activity from the
stems of Erycibe expansa. Planta Med., 70(12): 120-129.
� Meena B, Ezhilan RA, Rajesh R, Hussain KS, Ganesan B and Anandan R.
(2008). Antihepatotoxic potential of Sargassum polycystum
(Phaeophyceae) on antioxidant defense status in D galactosamine induced
hepatitis in rats. African J Biochem Res., 2(2): 51-55.
� Mehrola MN. (1990). Quality control and equipments of medicinal plants
used in traditional medicines ethanobotany, (2): 19-20.
Page 217 of 250
� Misra P, Pal NL, Guru PY, Katiyar JC and Tandon JS. (1991)
Antimalarial activity of traditional plants against erythrocytic stages of
Plasmodium berghei. Inter J Pharmacog, 29: 19-23.
� Modern VE. (2000). Approaches to herbal medicine. The
Eastern Pharm., 3: 35-8.
� Mohamed AF, AliHasan AG, Hamamy MI and Abdel Stattar E. (2005).
Anitoxidant and hepatoprotective effects of Eucalyptus maculata. Med.
Sci. Monit., 11(11): 426-431.
� Mrouesh M, Saab Y and Rizkallah R. (2004). Hepatoprotective activity of
Centaurium erythraea on acetaminophen–induced hepatotoxicity in rats.
Phytother Res, 18(5): 431-435.
� Murugaian P, Ramamurthy V and Karmegam N. (2008). Hepatoprotective
activity of Wedelia calendulacea against acute hepatotoxicity in rats. Res
J Agri Biol Sci., 4(6): 685-687.
� Nair CKN and Mohanan N. (2001) Medicinal plant of India, NAG
Publication, Delhi, India, 316-317.
� Oboth G. (2005). Hepatoprotective property of ethanolic and aqueous
extracts of Telfairia occidentalis leaves against garlic induced oxidative
stress. J Med Food, 8(4): 560-563.
� OECD. (1996). Guidelines for the testing of chemicals, Test no.423,
Acute Oral Toxicity Acute Toxic Class Method.
� Omkar A, Jeeja T and Chhya G. (2006). Evaluation of anti-inf lammatory
activity of Nyctanthes arbortristis and Onosma echiodes, Pharcogsy Mag,
2(8): 258-260.
Page 218 of 250
� Padma W, Suja V, Shyamala DCS and Prema. (1998). Hepatoprotective
effect of Liv 52 on antitubercular drug induced hepatotoxicity in rats.
Fitoterapia, 69(6): 520-22.
� Pandey M. (2009). Sida Veronicaefolia as a source of natural antioxidant.
International Journal of Pharmaceutical Sciences and Drug Research,
1(3): 180-182.
� Pari L and Uma A. (2003). Protective effect of Sesbania grandiflora
against erythromycin estolate induced hepatotoxicity. Therapie., 58(5):
439-443.
� Parotta JA. (2001). Healing plants of peninsular India, 3rd edi, CAB
International, Wallingford, U.K., 548-549.
� Paul BN and Saxena AK. (1997). Depletion of tumor necrosis factor α in
mice by Nyctanthes arbor tristis, Journal of Ethnopharmacology, 56:
153-158.
� Paul BN, Prakash A, Kumar S, Yadav Ak, Mani U, Saxena Ak, Sahu AP,
Lal K and Dutta KK. (2002). Silica indued early fibrogenic reaction in
lung of mice amelioratend by Nyctanthes arbortristis extract. Biomed
Environ Sci., 5(3): 215-222.
� Paya M, Ferrandiz ML, Sanz MJ and Alcaraz MJ. (1993). Effects of
phenolic compounds on bromobenzene mediated hepatotoxicity in mice.
Xenobiotica, 23: 327.
� PK Mukherjee. (2002). Quality control of herbal drugs, 1st ed, Business
Horizons Pharmaceutical Publication, New Delhi, 531.
Page 219 of 250
� Porchezhian E. and Ansari SH. (2005). Hepatoprotective activity of
Abutilon indicum on experimental liver damage in rats. Phytomed., 12(1-
2): 62-64.
� Porchezian E, Ansari SH. (2000). Effect of liquid extract from fresh
Abutilon indicum leaves and Alliumcepa bulbs on paracetamol and
carbontetrachloride induced hepatotoxicity. Pharmazie. 55(9): 702-3.
� Pramyothin P, Chirdchupunsare H, Rungsipipat A and Chaichantipyuth C.
(2005). Hepatoprotective activity of Thunbergia laurifolia extract in rats
treated with ethanol: In vitro and In vivo studies. J Ethnopharmacol.,
102(3): 408-411.
� Puri A, Saxena R, Saxena RP, Saxena KC, Srivastava V and Tandon JS.
(1994). Immunostimulant activity of Nyctanthes arbortristis. Journal of
Ethnopharmacology, 42(1): 31-37.
� Purushhothamam KK, Mathuram V and Ayyappath S. (1985).
Arbortristoside A and B, two iridoid glucosides from Nyctanthes
arbortristis, Phytochemistry, 24(4): 773-776.
� Gupta RS, Kachhawa JBS and Sharma R. (2006). Antispermatogenic
effects of Nyctanthes arbortristis in male albino rats. Pharmacologyonline
2: 261-273.
� Radha KD and Yogesh KC. (2005). Herbal medicines for liver diseases.
Digestive Diseases and Sciences, 50(10): 1807–1812.
� Raj DS, Vennila JJ, Aiyavu C and Panneerselvam K. (2009). The
hepatoprotective effect of alcoholic extract of Annona squamosa leaves
Page 220 of 250
on experimentally induced liver injury in swiss albino mice. Int J Int Bio,
5(3): 162-166.
� Ram VJ. (2001). Herbal Preparations as source of hepatoprotective
agents. Drug News Prospect, 14(6): 353-63.
� Ramachandra SS, Absar AQ, Viswanath Swamy AHM, Tushar PPT,
Prabhu K and Veeran GA. (2007). Hepatoprotective activity of
Calotropis procera flowers against paracetamol induced hepatic injury
in rats. Fitoterapia, 8: 451-454.
� Rana AC and Avadhoot Y. (1991). Hepatoprotective effects of
Andrographis paniculata against carbon tetrachloride – induced liver
damage. Arch. Pharm.Res., 14(1): 93-95.
� Rang HR and Dale MM. (2003). “Pharmacology”, Churchill Livingstone,
5: 391,509, 546, 557.
� Rao MS, Duddeck H and Dembinski R. (2002). Isolation and structural
elucidation of 3,4’,5,7 tetra acetyl quercetin from Adina cordifolia.
Fitoterapia, 73(4): 353-355.
� Rao VE. (2000). Modern Approach to Herbal Medicine. The Eastern
Pharmacist, 5: 35-7.
� Rasheed RA, Ali BH and Bashir AK. (1995). Effect of Teucrium
stocksianum on Paracetamol induced Hepatoxicity in Mice. J Pharmacol.,
26(2): 297-301.
� Rathee JS, Hassarajani SA and Chattopadhyay S. (2007). Antioxidant
activity of Nyctanthes arbortristis leaf extract. Food Chemistry 103:
1350–1357.
Page 221 of 250
� Rathod N, Raghuveer I, Chitme H. R and Chandra R. (2008). Antidiabetic
activity of Nyctanthes arbortristis. Pharmacognosy Magazine, 16: 335.
� Rathore A, Rivastava V, Srivastava KC and Tandon JS. (1990). Iridoid
glycosides from Nyctanthes arbortristis. Phytochemistry, 29(6): 1917-
1920.
� Rathore B, Paul B, Chaudhury BP, Saxena AK, Sahu AP and Gupta YK.
(2007). Comparative studies of different organs of Nyctanthes
arbortristis: In modulation of cytokines in murine model of arthrites.
Biomed. Environ Sci., 20(2): 154-159.
� Raza M, Ahmad M, Gado A and Al Shabanah OA. (2003) A comparison
of hepatoprotective activities of amino guanidine and N acetyl
cysteine in rat against the toxic damage induced by azathioprine.
Comparative Biochem Physiol., 134: 451-456.
� Rosa MP, Gutiérrez A and Rosario VS. (2009). Hepatoprotective and
inhibition of oxidative stress of Prostechea michuacana. Rec Nat Prod,
3(1): 46-51.
� Roy CK, Kamath JV, Asad M. (2006). Hepatoprotective activity of
Psidium guajava leaf extract. Ind J Exp Bio, 44(4): 305-311.
� Reitman S and Frankel S. (1957). Am J Clin Patho, 28: 56-63.
� Sabir M and Razdan MK. (1970). Anti-fertility study with leaf extract of
Adina cordifolia. Indian Journal of Physiology and Pharmacology, 14(3):
209-210.
Page 222 of 250
� Saleem MTS, Christina AJM, Chidambaranathan N, Ravi V and
Gauthaman K. Hepatoprotective activity of Annona squamosa on
experimental animal model. Int J Applied Res Nat Pro, 1(3): 1-7.
� Sangameswaran B, Chandraganth RT and Jayakar B. (2008).
Hepatoprotective effect of leaf extracts of Andrographis lineata on liver
damage caused by carbon tetrachloride in rats. J Phytother. Res, 22, 124-
126.
� Sangameswaran B, Deshraj C, Balakrishnan RB and Jaykar B. (2008).
Hepatoprotective effects of Thespesia lampas Dalz and Gibs in CCl4
induced liver injury in rats. J Pharma Sci, 7(1): 11-15.
� Saraswat B, Visen PKS, Dayal R, Agarwal DP and Patnaik GK. (1996).
Protective action of ursolic acid against chemical induced hepatotoxicity in
rats. Ind. J. Pharmaco, 28: 232-39.
� Sasmal D, Das S and Basu SP. (2007). Phytoconstituente and therapeutic
potential of Nyctanthes arbortristis. Pharmacognosy Reviews, 1 (2): 344-
349.
� Sasmal D, Das Sanjita and Basu S.P. (2008). Antianemic activity of
Nyctanthes arbortristis. Phcog Mag, 4(15): 56-58.
� Sathiya M, Parimal P and Muthuchelian. (2008). Preliminary
Phytochemical screening and antibacterial studies on ethanolic leaf
extrects of Nyctanthes arbortristis. Ethnobotanical Leaflets, 12: 337-342.
� Saxena RS, Gupta B and Lata S. (2002). Tranquilizing, antihistaminic and
purgative activity of Nyctanthes arbortristis leaf extract. Journal of
Ethnopharmacology, 81: 321-325.
Page 223 of 250
� Saxena RS, Gupta B, Saxena KK, Singh RC and Prasad DM. (2007)
Study of anti inflammatory activity in the leaves of Nyctanthes
arbortristis Linn. — an Indian medicinal plant. Journal of
Ethnopharmacology, 11(3): 319-33.
� Saxena RS, Gupta B, Saxena KK, Srivastava, VK and Prasad DN. (1987).
Analgesic, antipyretic and ulcerogenic activity of Nyctanthes arbortristis
leaf extract. Journal of Ethnopharmacology, 19(2): 193-200.
� Sembulingam K and Sembulingam P. (2004). Liver and Gallbladder:
Essentials of Medical Physiology. 3rd ed. New Delhi: Jaypee brother’s
medical publishers, 200-1.
� Shapiro H, Ashkenazi M, Weizman N, Shahmurov M, Hussein A and
Bruck R. (2006). Curcumin ameliorates acute ethanol induced
hepatotoxicity. J. Gastroenterol and Hepato, 21: 358-366.
� Shelly L and Neil K. (1989). “Drug induced Hepatotoxicity.” Current
Hepatology, 9: 105-133.
� Shirwaiker A, Sreenivasan KK, Krishnan BR and Kumar AV. (1996).
Chemical investigation and anti hepatotoxic activity of the root bark of
Caparis spinosa. Fitoterapia, 67 (3): 200-4.
� Shivashangari KS, Ravikuma V and Devaki T. (2004). Evaluation of the
protective efficacy of Asteracantha longifolia on acetaminophen induced
liver damage in rats. J Med Food, 7(2): 245-251.
� Singh A, and Hand SS. (1999). Hepatoprotective activity of Apium
graveolens and Hygrophila auriculata against paracetamol and
thioacetamide intoxication in rats. J Ethnopharmacol, 49(3): 119-126.
Page 224 of 250
� Singh B, Chandan BK, Prabhakar A, Taneja SC, Singh J and Qazi G N.
(2005). Chemistry and hepatoprotective activity of an active fraction from
Barleria prionitis in experimental animals. Phytother Res, 19(5): 391-404.
� Singh UK, Guru PY, Sen AB and Tandon JS. (1992). Antileishmanial
activity of traditional plants against Leishmania donovani in golden
hamsters. Ind. J Pharmacogy, 30: 289:295.
� Srivatsava SK and Gupta HO. (1983). A new flavanone from Adina
cordifolia. Planta Medica, 48 (5): 58:59.
� Stuppner H, Müller EP, Mathuram, V and Kundu AB. (1993). Iridoid
glycosides from Nyctanthes arbortristi. J. Phytochemistry, 32(2): 375-
378.
� Suja SR, Latha PG, Pushpangadan P and Rajesekharan S. (2004).
Evaluation of hepatoprotective effects of Helminthostachys zeylanica (L.)
Hook against carbon tetrachloride – induced liver damage in Wister rats. J
Ethonopharmacol, 92(1): 61-66.
� Sultana S, Perwaiz S, Iqbal M and Athar M. (1995). Crude extracts of
hepatoprotective plants, Solanum nigrum and Cichorium intybus inhibit
free radical mediated DNA damage. J Ethnopharmacol, 45: 189-192.
� Tandon JS, Srivastava V and Guru PY. (1991). Iridoids: A new class of
leishmanicidal agents from Nyctanthes arbortristis Linn. J Nat. Prod.
54(4): 1102-1104.
� Tang X, Gao J, Wang Y, Fan Y, Xu LZ, Zhao XN, Xu Q and Qian ZM.
(2006). Effective protection of Terminalia catappa L. leaves from damage
Page 225 of 250
induced by carbon tetrachloride in liver mitochondria. J Nutr Biochem,
17(3): 177-182.
� Tasduq SA, Kaisar P, Gupta DK, Kapahi BK, Maheshwari HS, Jyotsna S
and Johri RK. (2005). Protective effect of a 50% hydroalcoholic fruit
extract of Emblica officinalis against anti tuberculosis drugs induced liver
toxicity. Phytother Res, 19(3): 193-197.
� Thaibinh TT. (1998). Herbal Medicine. Indian J Pharm Edu, 32(2):
104-6.
� The Ayurvedic Phrmacopoeia of India. (1999). Government of India.
Ministry of Health and Family Welfare, New Delhi, I, (III): 235.
� Thyagarajan SP, Jayaram S, Gopalakrishnan V, Hari R, Jeyakumar P and
Sripathi MS. (2002). Herbal medicines for liver diseases in India. J
Gastroenterol Hepatol, 17 (3): 370-6.
� Tian YH, Kim HC, Cui JM and Kim YC. (2005). Hepatoprotective
constituents of Cudrania tricuspidata. Arch Pharm Res, 28(1): 44-48.
� Tortora GJ and Grabowski SR. (2002). The digestive system (liver and
gallbladder): Principles of Anatomy and Physiology. 7th ed. New York:
Harper Collins college publishers, 792-5.
� Tran QI, Adnyana IK, Tezuka Y, Nagaoka T, Tran QK and Kadota S.
(2001). J Nat Prod, 64: 456.
� Tuntiwachwuttikul P, Rayanil K and Taylor WC. (2003). Chemical
constituents from the flowers of Nyctanthes arbortristis. ScienceAsia, 29:
21-30.
Page 226 of 250
� Vadivu R, Krithika A, Biplab C, Dedeepya P, Shoeb N and Lakshmi KS.
(2008). Evaluation of hepatoprotective activity of the fruits of Coccinia
grandis Linn. Ind J Health Res, 1(3): 163.168.
� Valcheva Kuzmanova S, Borisova P, Galuska B, Krasnaliev I and
Belcheva A. (2004). Hepatoprotective effect of the natural fruit juice from
Aronia melanocarpa on carbon tetrachloride –induced acute liver damage
in rats. Exp Toxicol Pathol, 56(3): 195-201
� Vijayan P, Prashanth HC, Vijayaraj P, Dhanaraj SA, Badami Sand Suresh
B (2003). Hepatoprotective effect of the total alkaloid fraction of Solanum
pseudocapsicum leaves. Pharm. Biol. 41(6): 443-448.
� Vinodhini S, Malairajan S and Hazeena B. (2007). The hepatoprotective
effect of Bael Leaves (Aegle Marmelos) in alcohol induced liver injury in
albino rats. Int J Sci and Tech, 2(2): 83-92.
� Warrier PK, Nambiar VPK and Ramankutty C. (1996). Indian Medicinal
Plants. A Compendium of 500 species, In: Sida Cordata, Arya Vaidsala
publication, Kolkatta, India, 129-31.
� www. digestive.niddk.nih.gov/about/contact/htm.
� www.arizonatransplant.com/healthtopics/liver.html.
� www.conatuspharma.com/liverfacts/html.
� www.enjoylongerhealth.com/liver pic.html.
� www.hepfi.org/.
� www.liverfoundation.org/
� www.unos.org/.
Page 227 of 250
� Yue M, Yu CH, Ren K, Chen W and Li Y. (2006). Transient elevation of
hepatic enzymes in volunteers after intake of alcohol. Hepatobiliary Pancreat
Dis Int., 5(1): 52-55.
� Yue M, Yu CH, Ren K, Chen W and Li Y. (2009) Antiamoebic
coumarins from the root bark of Adina cordifolia and their new
thiosemicarbazone derivatives. Eur J Med Chem., 44(5): 2252-9.
� Zimmerman HJ, Ishak KG. (2002). “Hepatotoxin injury due to drugs and
toxins”. London, Churchill Livingstone, 4: 622-24.
� Zimmerman MD and Hayman J. (1976). Function and integrity of the
liver, In: Clinical diagnosis and management by laboratory methods In:
Clinical diagnosis and management by laboratory methods. 17th Ed, 217-50.
� Zimmerman MD and Hayman J. (1974). Alkaloid Constituents of Sida
acuta, S. humilis, S. rhombifilia and S. spinosa. Planta Med. 43: 384-8.