ENDOWMENT UPDATE Improving Brain FunctionTh e

REPRINT May 1, 2005 Edition online www.endowmentmed.org The Endowment for Medical ResearchTM

OUR PURPO SE: TO CONDUCT MEDICAL RESEARCH AN D EDUCATIONAL RESEARCH FOR IM PRO VED BRAIN FUN CTION IN CHILDREN AN D ADU LTS W ITHO UT DRU GS OR HARM FUL SIDE EFFECTS.

P. O. Box 73089, Houston, Texas 77273 • 281-587-2020 • FAX 281-893-6397 • Website: www.EndowmentMed.org

Alzheimer’s Studies • Stem Cell ResearchC a u s e a n d A n s w e r s Vs . S y m p t o m s

ImprovingBrain Function

by J. C. Spencer

Since we started the intense PilotSurveys in 2004 with scores of patientswith Alzheimer’s, Dementia, Stroke,Trauma, and Parkinson ranging fromearly stages to advanced patients in carefacilities, we have gathered a lot of dataand learned much from these studies. This report is not about those studies. Those findings are scheduled to appearin medical papers authored by MedicalWriters: Patricia Smith (author of“Alzheimer’s” published in the Dummiesseries), H. Reg McDaniel, M.D., CharlesEschweiler, and another university basedprinciple investigator. This report is on our findings leadingup to the Pilot Surveys and oninformation we have gained in thestudies, not the studies themselves. Cognizant studies are of great interestto us and play major roles in ourunderstanding brain function. It is ourintent that the surveys will helpdetermine ways and means of improvingacademic achievement in children andimproved brain function in adults. Cognizant and physical responseshave been documented to be improv-ed when the science of Glycomics isintegrated into the equation. A combi-nation of certain micronutrients in theform of glyconutrients, phytonutrients,and phytogenins, taken orally, producepositive alertness response, sometimesevidenced within minutes. This knowl-edge demands continued research todetermine the best pathway for optimalsuccess. The Endowment for Medical Researchplans to continue gathering researchdata in the area of brain functionchallenges in preparation for majorresearch funding. Our studies so far have determined atleast three commonalities of brainfunction that Alzheimer’s victims have

that we believe research will indicate canbe addressed:1) There is a protein plaque build-up on the neurons;2) There is a near depletion of Dehydroepiandrosterone (DHEA) in the brain; and,3) It is reported to us that Lecithin, normally abundant in the brain is reduced. The Endowment is committed toinvestigate and document functionalvariations in the human brain. There are already discoveries inmainstream medical universities thatfuture studies of the brain need (toovercome the risk of misleading results)to take into consideration certain aspectsof structure and function including thedifferences in male and female brain. Our studies are two fold:(1) Discover and document how Glycomics aid brain function.(2) Discover other sciences that aid Glycomic’s ability to improve brain function. Stanford University’s Seymour Levinein 1966 wrote an article published inScientific American entitled “SexDifferences in the Brain”. While much ofhis view has been put on the shelf, histhoughts helped generate a generationof neuroscientists that concluded thatindeed there are differences in the braincaused by hormones. Technological advances can view andmonitor the brain of a living being insophisticated noninvasive imagingtechniques including positron-emissiontomography (PET) and functionalmagnetic resonance imaging (fMRI). Neuroscientists are beginning toexplore the possibilities in determining ifthe number of neurons correlate with thedifferences in cognitive abilities. H. Reg McDaniel, M.D. believes we areable to proliferate the patient’s produc-tion of stem cells and thereby increasethe number of neurons in the brain.

Through the Pilot Surveyswe are conducting followingDr. H. Reg McDaniel’s direction,we are able to documentimprovement in brain function.

Hormones andBrain Function

It is the author’s conviction that notonly do hormones play a major role inbrain function but that specific hormonesintegrated with Glycomics can improvebrain function. It appears to us that in many cases,stress caused by a traumatic situationoccurred in the past and most likelycontributed to or even precipitated manyof today’s health challenges fromAlzheimer’s to Fibromyalgia & ChronicFatigue Syndrom. Stress is a major cause of theconsumption and depletion of dehydroepiandrosterone from theblood stream. This depletionaccelerates the aging process and bringson an onslaught of diseases by loweringthe immune system. This hormonewhich is at the apex of our hormonalsystem is designed into the brain at aconcentrated level six and a half (6½)time that it is in the blood stream. How-ever, according to Ward Dean, M.D., inhis book, “Smart Drugs”, the brain of anAlzheimer’s patient is missing the vitalhormone, dehydroepiandrosterone.

Dehydroepiandrosteroneis missing in the brain ofan Alzheimer’s patient.

If the stress of a stroke or othertraumas depletes this hormone thatcontributes to the production of allhormones, is there any way of getting itback?

We believe that the protocol we areusing in our Pilot Surveys is increasingthe hormonal levels in the brain butcurrently we have no means of provingthat. Detection of that hormone in thebrain can be achieved only through anautopsy and we have had no volunteers.

Myelin Sheath

damagecontributes to ManyHealth Challenges

Myelin is an insulating layer

that forms around nerves. It

is made up of protein and

fatty substances.Reprinted from our Autism NEWSletter 11/04

The Myelin Sheath of a neuronconsists of fat-containing cells thatinsulate the axon from the electricaltransmission of signals. A gap existsbetween each myelin sheath cell alongthe axon. Since fat inhibits the flow ofelectricity, the signals jump from one gapto the next. Multiple sclerosis ischaracterized by patches of demyelina-tion (destruction or loss of the myelinsheath) in the central nervous system. The symptoms that result from this

demyelination are determined by thefunctions normally contributed by theaffected neurons. Disruption of musclecontrol, speech and visual disturbancesare common and is evident in MS,Parkinson, and other diseases.

The Advanced Tutorial states: Themyelin sheath (a tubular case orenvelope) give the whitish appearance tothe white matter of the brain. Myelincells are included in the category of Glialcells. Glial cells function to support theprocesses of neurons in a variety ofways. The glial cells forming myelinsheaths are called oligodendrocytes inthe central nervous system and Schwanncells in the peripheral nervous system. The gaps (approx. 1 micrometer wide)formed between myelin sheath cellsalong the axons are called Nodes orRanvier. Since fat serves as a good insulator,the myelin sheaths speed the rate oftransmission of an electrical impulse

along the axon. The electrical impulsejumps from one node to the next at arate as fast as 120 meters per second. This rapid rate of conduction is calledsaltatory conduction. For the brain to work, it must beconnected. NOTE: This knowledge may help us tobetter understand how hydrogenated oilsARE silent killers and why good oils giveus a better quality of life.

Stem CellsHold the Answers:Making the Connection Stem cells produce neurons.

Stem cells are known for their

ability to migrate to any part of the

human body that needs repair

including the brain. Stem cells seem

to move to the area of greatest need

to do their work.

Stem cells are produced in the

bone marrow. A bone marrow

transplant may cost up to $300,000.

You can harvest your own stem cells,

if they are healthy, and have them

frozen and later injected back into

your own body after radiation or

chemotherapy for about $100,000.

Umbilical stem cells can be

harvested from a newly born baby

without harm to the child and later

used in a compatible recipient for

$14,500 to $21,000.

Visit our website

endowmentmed.org

In addition to being a very

informative website, we have posted

three NEW S Bulletin Boards:

Health NEWSStem Cell NEWS andKids NEWS

The Endowment for

Medical Research

P. O. Box 73089Houston, Texas 77273281-587-2020

Address Service Requested

Major Medical ConferenceSponsored by The Endowment

for Medical Research

October 8, 2005 - HoustonVisit: www.endowmentmed.org and

click on Conference for details.

Glycomics

Everyhealthcareprofessionalshould havethis StemCell SurveyCD by H. Reg McDaniel, M.D. whichdocuments how Dr. McDaniel discoveredthe glyconutrient growth factor for stemcell proliferation in the human body. Learn how Stem Cell proliferation maybenefit Alzheimer’s and other braindysfunctions. This CD plus a DVD of Dr.McDaniel presenting the study isavailable for a contribution of $50. Thismay be purchased online atwww.EndowmentMed.org or by calling281-587-2020. Studies are under way or planned atThe Endowment for Medical Researchincluding Autism, Down Syndrome,ADhD, Alzheimer’s, Dementia, ALSParkinson, Huntington chorea, Trauma,and Stroke.See www.EndowmentMed.org.Necessary forms are online.

G