Post on 22-Aug-2020
CURRICULUM VITAE
GENE GABRIEL GURKOFF
EDUCATION
2006 Ph.D. in Neuroscience, Laboratory of Dr. David Hovda,
Neuroscience Interdepartmental Program, University of California
Los Angeles, Los Angeles, CA
1998 B.S., Honors, in Neuroscience, Brown University, Providence, RI
RESEARCH INTERESTS
My primary research interests are in evaluating mechanisms and developing innovative
treatments for traumatic brain injury and epilepsy patients. Currently the field of
traumatic brain injury focuses primarily on developing neuroprotective compounds to
reduce cell death following injury. The majority of epilepsy research is related to
reducing seizures. However, patients with traumatic brain injury and epilepsy both
present with a range of behavioral disorders, with cognitive disability being a common
co-morbidity. There are currently minimal efforts to develop innovative therapies to
improve cognition in chronic TBI and epilepsy patients. My laboratory uses animal
models of traumatic brain injury and epilepsy to better understand the physiological and
anatomical basis for chronic cognitive and social deficits in both the pediatric and adult
rat. Our current focus is on using advanced in vivo electrophysiology techniques to
identify systems-level changes in brain function with the goal of developing novel and
innovative neuromodulatory approaches for treating patients suffering chronic cognitive
deficits related to traumatic brain injury or epilepsy. Our ultimate goal is to translate
these innovative treatment strategies from the bench to the bedside.
RESEARCH EXPERIENCE
2018 – present Director of UC Davis Neurological Surgery Research Laboratory
2014 – present Assistant Professor, Department of Neurological Surgery,
University of California Davis, Davis, CA.
2012 - 2014 Assistant Professional Researcher, Department of Neurological
Surgery, University of California Davis, Davis, CA.
2007 - 2012 Postdoctoral Fellow, Department of Neurological Surgery,
University of California Davis, Davis, CA. Advisor Dr. Bruce
Lyeth
2010 - 2011 Post-Doctoral Fellow, Banyan Biomarkers Inc, Gainesville, FL
2006 – 2007 Postdoctoral Fellow, Department of Surgery, Division of
Neurosurgery, University of California Los Angeles, Los Angeles,
CA. Advisor: Dr. Richard Sutton,
1998 – 2000 Staff Research Associate II, Laboratory of Dr. Allen Basbaum,
Department of Anatomy, University of California San Francisco,
San Francisco, CA
1996 – 1998 Undergraduate Research Assistant, Laboratory of Dr. J. Michael
Walker, Brown University, Providence, RI
1996 – 1997 Summer Intern, Connectics Inc., Palo Alto, CA
TEACHING EXPERIENCE
2018 Instructor of Record NSC298 Rocks and Shoals. A career
development course for neuroscience graduate students. Invited 9
guest speakers with either expertise in career development or who
had chosen careers outside of academia to meet with graduate
students and led discussions. (10 weeks, 1 hour/week)
2018 Instructor of Record NSC271C Translational Approaches to
Learning, Memory, and Plasticity Disorders. I developed the
curriculum of the course to focus around three disease areas per 10
weeks of instruction. In successive weeks the clinical condition
was discussed followed by strategies for in vivo and then in vitro
research respectively. (10 weeks, 2 hours/week)
2017 Instructor PTX 203 Principles of Pharmacology and Toxicology
III. Graduate level class. Included traditional instruction (2 hours)
pertaining to neurotransmitters with a subsequent case study (1
hour)
2017 Instructor of Record FRS 003 007 Neurobiology of Learning
(Freshman seminar). Small group based instruction. Co-taught
with my post doctoral fellow Dr. Alex Pevzner (10 weeks, 1
hour/week)
2017 - present Instructor VMB 234 Current Topics in Neurotoxicology.
Graduate level course. Lectured on excitotoxicity (1 hr).
2017 Instructor NSC298 Rocks and Shoals. A career development
course for neuroscience graduate students. Discussed “two body
problem” and how to develop a 2 and 5 min research pitch (2
weeks, 1 hour/week)
2016 - present Instructor of Record FRS 003 027 Brain stimulation (Freshman
seminar). Small group based instruction (10 weeks, 1 hour/week)
2016 - 2017 Instructor and Mentor First Year Aggie Connection. This was a
discussion section offered to incoming community college transfer
students aimed to develop balance and a routine in their daily
schedule (10 hrs)
2016 - present Instructor NSC 201 Neuroanatomy. Graduate level course.
Lectured on the anatomy of the cerebellum (1 hr)
2015 Instructor Doctoring AMP 1 (School of Medicine). Small group
case-based instruction (6 hrs). Topic: Chronic obstructive
pulmonary disease.
2014 Instructor Doctoring AMP 1 (School of Medicine). Small group
case-based instruction (6 hrs). Topic: Lead poisoning.
2010 Instructor and Mentor (winter internship), Winter Internship for
Community College Students (CC Winter; 100 hours), Helped to
implement and supervise a two-week intensive laboratory course.
Prepared and presented three lectures (30 minutes each), Center of
Biophotonics Science and Technology at UC Davis, Jan 4-15th
2010.
2009 - 2011 Instructor (summer internship), Summer Internship for the Center
of Biophotonics at UC Davis. Proposed, designed and led a
Neuroscience and Biophotonics Journal Club (5 hours/week)
2009 - 2011 Organizer and Instructor, Summer Internship for the Center of
Biophotonics at UC Davis June 15 - 20. Assisted in the design and
implementation of a one-week intensive program (40 hours)
2009 Instructor and Mentor (winter internship), Winter Internship for
Community College Students (CCWinter; 15 hours), Center of
Biophotonics Science and Technology at UC Davis, Jan 5-16,
2009
2009 - present Instructor Basic Science (neurosurgical residents), Department of
Neurological Surgery, UC Davis School of Medicine (2-5 hours
annually). Lectures include: anatomy, plasticity, excitotoxicity,
neuromodulation.
2008 - 2013 Instructor, IST 8A (freshman course), Integrated Studies,
Invitational Honors Program, Introduction to Biophotonics (1.5
hours). Lecture: Applying the Scientific Method to Biophotonics.
2008 – 2009, 2012 Instructor, EAD/BIM 289 (graduate course), Selected Topics in
Biophotonics (2 hours). Lecture: Applying Biophotonics to CNS
Injury.
2001 and 2002 Teaching Assistant, Neuroanatomy 102 (undergraduate course),
Department of Neuroscience, David Geffen School of Medicine at
UCLA, Los Angeles, CA (10 weeks). Supervised weekly labs,
held weekly office hours (2 hrs/week), prepared and taught one
review session (10 hrs).
Other Teaching Experience
2012 – 2017 Mentor. University of Davis, California Alliance for Minority
Participation (CAMP) program. This program is designed to
present opportunities in research for under-represented and
economically disadvantaged students who have an interest in
pursuing a graduate degree (4 total students).
2012 – present Mentor. Biology Undergraduate Scholars Program (BUSP) –
Honors. This program is designed to present opportunities in
research for under-represented and economically disadvantaged
students who have an interest in pursuing a graduate degree. I give
annual presentations on lab etiquette as well as a basic science
lecture to the entire class. In addition I mentor individual students
within the program (5 total students, 2 active).
2012 Mentor. Mentorship for Undergraduate Research in Agriculture,
Letters and Science (MURALS). This program is designed to
present opportunities in research for under-represented and
economically disadvantaged (1 former student).
2007 – 2013 Mentor. Center for Biophotonics Science and Technology
Internship. This program is designed to present opportunities in
research for under-represented and economically disadvantaged
who are pursuing a career in medicine or research (13 former
students).
2013 - present Moderator. Moderate an oral presentation session at the annual
Undergraduate Research Conference (URC).
RESEARCH MENTORING EXPERIENCE
Postdoctoral Fellows
2018 – present Ali Izadi. Received a PhD in neuroscience from UC Davis
2018 – present Amber Schedlbauer. Received a PhD in neuroscience from UC
Davis.
2015 - 2017 Alexzander Pevzner. Received a PhD in neuroscience from UC
Irvine. Currently an Assistant Professor at Notre Dame de Namur
University.
Neurosurgery Residents
2017 – 2018 Tamar Binyamin. Currently chief resident in UC Davis
Neurological Surgery residency program. Received her MD from
Virginia Commonwealth University.
2018 – 2019 Amir Goodarzi. Received his MD from UC Davis.
Graduate Students
2016 - present Katelynn Ondek a dual degree student in the Department of
Veterinary Medicine and the UC Davis Neuroscience Graduate
Group
2016 - 2018 Kayleen Tercovich a member of the UC Davis Neuroscience
Graduate Group. Received her masters degree in Spring 2018.
Currently employed by The Jackson Laboratories.
2013 - present Ali Izadi, a member of the UC Davis Neuroscience Graduate
Group. Currently a post-doctoral fellow in my lab.
2010 – 2012 Darrin Lee, a member of the UC Davis Neuroscience Graduate
Group and Neurosurgery Resident. Currently an Assistant
Professor in Neurosurgery at University of Southern California.
Medical Students
2016 – 2017 Lucy Ogbu-Nwobodo. A T32 scholar between 3rd
and 4th
year of
medical school. Currently in a Psychiatry residency program at
Harvard University.
2015 – 2016 Arjang Ahmandpour. A T32 scholar between 3rd
and 4th
year of
medical school. Currently in a Neurosurgical residency program at
University of Chicago.
Rotating Graduate Students
2016 Brendan Cohn-Sheehy. Currently in his 3rd
year of Neuroscience
Graduate School.
2018 Gregory Disse. Currently a MS2 in medical school.
Undergraduate
2019 – present Francisco Valverde, a UC Davis Undergraduate (6 hrs/week)
2018 – present Myat Wai, a UC Davis Undergraduate (6 hrs/week)
2018 – present Consuelo Jimenez-Ornelas, a UC Davis Undergraduate (8
hrs/week)
2017 – present Olga Brevnova, a UC Davis Undergraduate (8 hrs/week).
2016 - 2017 Pedro Hernandez, a UC Davis Undergraduate (10 hrs/week).
2016 - 2017 Matthew Culberson, a UC Davis Undergraduate (3 hrs/week).
2015 - 2018 Emily Hsu, a UC Davis Undergraduate (6 hrs/week)
2014 and 2015 Anthony Fong, summer intern from the UC Santa Cruz (25
hrs/week). Currently a technician in the Dr. Edward Chang lab at
UCSF.
2014 and 2015 Abby Scurfield, summer intern from the University of Puget Sound
(25 hrs/week). Current position unknown.
2014 - 2016 Sunny Yu, a UC Davis undergraduate (10 hrs/week). Current
position unknown.
2014 - 2017 Eman Meky, a UC Davis undergraduate (10 hrs/week) and CAMP
Summer Program (32 hrs/week). Recently graduated and studying
for the MCAT.
2013 - 2016 Lauren Ekman, a UC Davis undergraduate (6 hrs/week). Recently
completed a masters degree program at USC.
2013 Fritz Libby, a undergraduate at California State University,
Northridge, and Minority Biomedical Research Support / Research
Initiative for Scientific Enhancement Intern (40 hrs/week for 10
weeks). Current position unknown.
2012 - 2015 Mikhail Melnik, a UC Davis undergraduate (10 hrs/week), and UC
Davis Center for Biophontonics Science and Technology Summer
Intern (35 hrs/week for 12 weeks). Currently a neuroscience
graduate student at UCLA.
2012 - 2015 Rafael Ordaz, a UC Davis undergraduate (10 hrs/week) and UC
Davis Center for Biophotonics and Science and Technology
Summer Intern (35 .hrs/week for 12 weeks). Current position
unknown
2012 - 2015 Angela Avitua, a UC Davis undergraduate (8 hrs/week) and UC
Davis Center for Biophotonics and Science and Technology.
Summer Intern (35 hrs/week for 12 weeks). Currently a
neuroscience graduate student at University of California,
Riverside.
2012 - 2015 Haroon Shafique, a UC Davis undergraduate (8 hrs/week) and UC
Davis Center for Biophotonics and Science and Technology
Summer Intern (35 hrs/week for 12 weeks). Currently employed at
Genentech.
2012 Laura Brouchard, a UC Davis undergraduate (6 hrs/week for 1
quarter). Currently a second year medical student at UCSF.
2012 Hunter Trice, a UC Davis undergraduate (2011 – 2012 (6 hrs/week
for 2 quarters). Current position unknown
2012 Simon Chang, a UC Davis undergraduate (6 hrs/week for 2
quarters). Current position unknown
2011 - 2014 Nick Yin, a UC Davis undergraduate (8 hrs/week). Current
position unknown
2011 - 2014 Anup Sonti, a UC Davis undergraduate (6 hrs/week). Currently a
first year medical student at Hofstra Northwell School of
Medicine.
2011 - 2012 Heather McConnell, a UC Davis undergraduate (8 hrs/week).
Received her PhD from Oregon Health Sciences and is currently a
post-doctoral scholar.
2011 - 2013 Rebecca Wong, a UC Davis undergraduate (6 hrs/week). Currently
employed by Genentech.
2011 - 2014 Tomas Tesfasilassie, a UC Davis undergraduate (10 hrs/week) and
UC Davis Center for Biophotonics and Science and Technology
Summer Intern (35 hrs/week for 12 weeks). Currently in medical
school at UCSF.
2010 - 2011 Andrea Domingo, a UC Davis undergraduate (8 hrs/week). Current
position unknown
2010 - 2011 Jennifer Gahan, a UC Davis undergraduate (8 hrs/week).
Currently a PGY2 resident in Surgery at University of North
Carolina.
2010 - 2013 Rahil Ghiasvand, a UC Davis undergraduate (8-12 hrs/week) and
UC Davis Center for Biophotonics and Science and Technology
Summer Intern (35 hrs/week for 12 weeks). Currently enrolled in
the Marine Science and Watershed Systems Masters Program at
California State University, Monterey.
2010 & 2011 M. Hiram Dominguez, a University of Santa Barbara
undergraduate. UC Davis Center for Biophotonics and Science
Technologies Summer Intern (35 hrs/week for 12 weeks and 2
summers). Currently employed as a laboratory technician at UC
Merced.
2010 Carissa Perez, a University of San Diego undergraduate. UC Davis
Center for Biophotonics and Science Technologies Summer Intern
(35 hrs/week for 10 weeks). Current position unknown.
2008 – 2010 Vanessa Atkinson, a UC Davis undergraduate (6-8 hrs/week) and
UC Davis Center for Biophotonics and Science and Technology
Summer Intern (35 hrs/week for 12 weeks). Currently a charge
nurse at the Palo Alto VA.
2008 - 2010 Paul Mello, UC Davis undergraduate (6 hrs/week) and UC Davis
Center for Biophotonics and Science and Technology Summer
Intern (35 hrs/week for 12 weeks). Currently an In-Hospital
Pharmacist at Kaiser Oakland Medical Center.
2008 & 2009 Justiss Kallos, an Emory University Undergraduate. UC Davis
Center for Biophotonics and Science Technologies summer intern
(35 hrs/week for 10 weeks). Currently a 4th
year medical student at
Vanderbilt.
2007 & 2008 Bryan Brandon, a California State San Louis Obispo
undergraduate. UC Davis Center for Biophotonics and Science
Technologies summer intern (35 hrs/week for 12 weeks and 2
summers). Currently a PGY4 in a Head and Neck Surgery
Residency Program at University of North Carolina.
2007 Cristal Resto, Solano College undergraduate. UC Davis Center for
Biophotonics and Science Technologies summer intern (35
hrs/week for 12 weeks). Current position unknown.
High School
2019 Amanda Soeth, a student at Davis Highschool. Amanda
participated in a 70 hr internship (Jan – May) as a part of her high
school biotechnology class.
2019 Jessica Bennett, a student at Davis Highschool. Jessica participated
in a 70 hr internship (Jan – May) as a part of her high school
biotechnology class.
2018 Jillian Fahey, a student at Davis Highschool. Jilian participated in a
70 hr internship (Jan – May) as a part of her high school
biotechnology class.
PEER-REVIEWED PUBLICATIONS
1. Gurkoff GG, Giza CC, Hovda DA. Lateral Fluid Percussion Injury in the
Developing Rat Causes An Acutre, Mild Behavioral Dysfunction in the Absence
of Significant Cell Death. Brain Research 1077(1); 24-36, 2006.
2. Myer DJ, Gurkoff GG, Norton D, Lee SM, Hovda DA, and Sofroniew MV.
Essential Protective Roles of Reactive Astrocytes in Traumatic Brain Injury.
Brain 129(Pt 10); 2761-2772, 2006.
3. Zhang B, West EJ, Van KC, Gurkoff GG, Zhou J, Zhang X-M, Kozikowski AP,
Lyeth BG. HDAC Inhibitor Increases Histone H3 Acetylation and Reduces
Microglia Inflammatory Response Following Traumatic Brain Injury in Rats.
Brain Research 1226; 181-191, 2008.
4. Gurkoff GG, Shin D, Auvin S, Sankar R, Hovda DA. Acute Neuroprotection to
Pilocarpine-Induced Seizures is Not Sustained After Traumatic Brain Injury in the
Developing Rat. Neuroscience 164(2); 862-876, 2009
5. Shahlaie K, Lyeth BG, Gurkoff GG, Muizelaar JP, Berman RF. Neuroprotective
Effects of Selective N-Type VGCC Blockade on Stretch Injury-Induced Calcium
Dynamics in Cortical Neurons. J Neurotrauma 27(1); 175-187, 2010.
6. Feng J, Van KC, Gurkoff GG, Kopriva C, Song M, Yuen P, Jiang J, Zhou J,
Lyeth BG. Post-injury administration of NAAG peptidase inhibitor prodrug, PGI-
02776, in experimental TBI. Brain Research 1395; 62-73, 2011.
7. Beller JA, Gurkoff GG, Berman RF and Lyeth BG. Pharmacological
Enhancement of Glutamate Transport Reduces Excitotoxicity. Restorative
Neurology and Neuroscience 29(5); 331-346, 2011.
8. Feng J*, Zhao, X*, Gurkoff GG, Van KC, Shahlaie K, and Lyeth BG.
Posttraumatic Hypoxia Exacerbates Neuronal Cell Death in the Hippocampus J
Neurotrauma 29(6); 1167-1179, 2012.
9. Gurkoff GG, Shahlaie K, and Lyeth BG. In vitro mechanical strain trauma alters
neuronal calcium responses: Implications for posttraumatic epilepsy. Epliepsia
53(suppl.1); 53-60, 2012.
10. Feng J, Gurkoff GG, Van KC, Song M, Lowe DA, Zhou J, and Lyeth BG.
NAAG Peptidase Inhibitor Reduces Cellular Damage in a Model of TBI with
Secondary Hypoxia. Brain Research 1469; 144-152, 2012.
11. Lee DJ, Gurkoff GG, Izadi A, Berman RF, Ekstrom AD, Muizelaar JP, Lyeth
BG and Shahlaie K. Medial septal nucleus theta frequency deep brain stimulation
improves spatial working memory after traumatic brain injury. J Neurotrauma
30(2); 131-139, 2013.
12. Gurkoff GG, Gahan JD, Ghiasvand RT, Hunsaker MR, Van K, Feng JF, Shahlaie
K, Berman RF, Lyeth BG, and Folkerts MM. Evaluation of metric, topological
and temporal ordering memory tasks after lateral fluid percussion injury. J
Neurotrauma 30(4); 292-300, 2013.
13. Shahlaie K*, Gurkoff GG*, Lyeth BG, Muizelaar JP, and Berman RF.
Neuroprotective effects of SNX-185 in an in vitro model of TBI with a second
insult. Restorative Neurology and Neuroscience 31(2); 141-153, 2013.
14. Watrous AJ*, Lee DJ*, Izadi A, Gurkoff GG, Shahlaie K, and Ekstrom AD. A
comperative study of human and rat hippocampal low frequency oscillations
during spatial navigation. Hippocampus 23(8); 656-661, 2013.
15. Gurkoff GG, Feng JF, Van KC, Izadi A, Ghiasvand RT, Shahlaie K, Song M,
Lowe DA, Zhou J, and Lyeth BG. NAAG peptidase inhibitor improves motor
function and reduces cognitive dysfunction in a model of TBI with secondary
hypoxia. Brain Res 1515; 98-107, 2013.
16. Gurkoff GG, Shahlaie K, Lyeth BG, and Berman RF. Voltage-Gated Calcium
Channel Antagonists and Traumatic Brain Injury (Review). Pharmaceuticals 6(7);
788-812, 2013.
17. Lee DJ, Gurkoff GG, Goodarzi A, Muizelaar JP, Boggan JE, and Shahlaie K.
Intracerebroventricular opiate infusion for refractory head and facial pain. World
Journal of Clinical Cases 2(8); 351-356, 2014.
18. Lee DJ, Gurkoff GG, Izadi A, Echeverri A, Melnik M, Berman RF, Ekstrom AD,
Muizelaar JP, Lyeth BG, and Shahlaie K. Hippocampal theta frequency
modulation for cognitive and electrophysiological improvement following
traumatic brain injury. J Neurotrauma 32(22); 1822-1832, 2015.
19. Kolarik BS, Shahlaie K, Hassan A, Borders AA, Kaufman KC, Gurkoff GG,
Yonelinas AP, and Ekstrom AD. Impairments in precision, rather than spatial
strategy, characterize performance on the virtual Morris Water Maze; A case
study. Neuropsychologia 80; 90-101, 2015.
20. Pevzner A, Izadi A, Lee DJ, Shahlaie K, and Gurkoff GG. Making Waves in the
Brain: What Are Oscillations, and Why Modulating Them Makes Sense for Brain
Injury (Review). Front Syst Neurosci. 2016.
21. Lee DJ, Izadi A, Melnik M, Seidl S, Echeverri A, Shahlaie K, and Gurkoff GG.
Stimulation of the medial septum improves performance in spatial learning
following pilocarpine-induced status epilepticus. Epilepsy Res. 130; 53-63, 2017.
22. Scangos KW, Carter CS, Zhang L, Gurkoff GG, and Shahlaie K. Theta
frequency stimulation of the subthalamic nucleus improves cognitive dysfunction
in Parkinson’s disease. Brain Stimulation. 11(2); 456-458, 2018.
23. Izadi A*, Ondek K*, Schedlbauer A, Keselman I, Shahlaie K, and Gurkoff GG.
Clinically Indicated Electrical Stimulation Strategies to Treat Patients with
Medically Refractory Epilepsy Open. 2018.
24. Izadi A, Pevzner A, Lee DJ, Ekstrom A, Shahlaie K, and Gurkoff GG. Medial
septal nucleus stimulation increases seizure threshold and improves cognitive
function in a rodent model of temporal lobe epilepsy. Brain Stimulation (in press)
Submitted
1. Moxon K, Shahlaie K, Girgis F, Saez I, and Gurkoff GG. From adagio to
allegretto: The changing tempo of theta frequencies in epilepsy and its relation to
interneuron function. (submitted to Neurobiology of Disease; November 2018)
In Preparation
1. Izadi A, Ondek K, Schedlbauer A, Ekstrom AD, Shahlaie K and Gurkoff GG.
Theta stimulation of the medial septum during epileptogenesis reduces seizures
and improves cognitive outcome.
2. Ondek K*, Pevzner A*, Tercovich K*, Izadi I, Schedlbauer A, Ekstrom AD,
Cowen S, Shahlaie K and Gurkoff GG. Traumatic brain injury results in
depressed oscillations across the septohippocampal circuit.
ABSTRACTS AND PRESENTATIONS
Poster Presentations:
1. Malmberg A, Gurkoff GG, Gilbert H, Zhou L-M, McCabe T, Basbaum AI.
Antinociceptive Effects of Cone Snail Venom-Derived Subtype-Selective
NMDA-Receptor Antagonists. Society for Neuroscience, 25:921, 1999.
Presented at the 29th
Annual Society for Neuroscience Meeting, Miami, FL,
October 23-28, 1999.
2. Gurkoff GG, Wagstaff JD, Layer RT, McCabe T, Basbaum AI. Antinociceptive
Effects of Spinal Contulakin-G, A Cone Snail-Derived Neurotensin. Society for
Neuroscience Annual Meetings Abstracts Volume (26), 2000. Presented at the
30th
Annual Society for Neuroscience Meeting, New Orleans, LA, November 4-9,
2000.
3. Trafton JA, Gurkoff, GG, Basbaum AI. Consequences of Mu Opiod Receptor
(MOR) Internalization for Morphine-Induced Analgesia and Tolerance. Society
for Neuroscience Annual Meetings Abstracts Volume (27) 2001. Presented at the
31st Annual Society for Neuroscience Meeting, San Diego, CA, November 10-15,
2001.
4. Gurkoff GG, Giza CC, Hovda DA. Behavioral Deficits Following Lateral Fluid
Percussion Injury in the Rat Pup Due to Cellular Dysfunction and Not Cell Death.
Journal of Neurotrauma, 19(10);1320, 2002. Presented at the 20th
Annual National
Neurotrauma Society Symposium, Tampa, FL and the 6th
International
Neurotrauma Symposium, October 27 – November 1, 2002.
5. Gurkoff GG, Hoffmann JR, Giza CC, Hovda DA. Injury Severity Does Not
Predict Outcome in a Model of Developmental Lateral Fluid Percussion. Journal
of Neurotrauma 20(10);1093, 2003. Presented at the 21st Annual National
Neurotrauma Society Symposium, Biloxi, MS, November 6-7, 2003.
6. Gurkoff GG, Shin D, Reger M, Giza CC, Sankar R, Hovda DA. Lateral Fluid
Percussion Sustained Early in Life Protects Hippocampal Cells from Secondary
Seizure. Journal of Neurotrauma, 21(9);1341, 2004. Presented at the 22th
Annual
National Neurotrauma Society Symposium, San Diego, CA, October 21-22, 2004.
7. Gurkoff GG, Shin D, Giza CC, Hovda DA, and Sankar R. Concussive Brain
Injury Produces a State of Preconditioning in the Developing Rat Brain. Annals
of Neurology, 58(S9); S115, 2005. Presented at the 34th
Child Neurology Society
Annual Meeting, Los Angeles, CA, September 28 – October 1, 2005.
8. Reger ML, Gurkoff GG, Hovda DA, and Giza CC. The Novel Object
Recognition Task Detects a Transient Cognitive Deficit After Developmental
TBI. Journal of Neurotrauma, 22(10);1206, 2005. Presented at the 23rd
Annual
National Neurotrauma Society Symposium, Washington D.C., November 10-11,
2005.
9. Gurkoff GG, Shin D, Auvin S, Giza CC, Sankar R, and Hovda DA. Concussive
Brain Injury and Status Epilepticus: Acute Preconditioning Does Not Translate to
Long-Term Hippocampal Protection From Seizures. Journal of Neurotrauma,
23(6); 1031, 2006. Presented at the 24th
Annual National Neurotrauma Society
Symposium, St. Louis, MO, July 7-9, 2006.
10. Hutson C, Gurkoff GG, Giza CC, Hovda DA, and Chesselet MF. Multiple Risk
Factors for Parkinson’s Disease: Pesticide Exposure and Traumatic Brain Injury.
Journal of Neurotrauma, 24(7); 1232, 2007 Presented at the 25th
Annual National
Neurotrauma Society Symposium, Kansas City, MO, July 30-Aug 1, 2007.
11. Gurkoff GG, Katleba KD, Justin JA, and Lyeth BG. Changes in Extracellular
Potassium Influence Injury-Related Neuronal Activity and Cell Death. Journal of
Neurotrauma, 25(7); 926, 2008. Presented at the 26th
Annual National
Neurotrauma Society Symposium, Orlando, FL, July 27-30, 2008.
12. Zhang B, West E, Van K, Gurkoff GG, Kozikowski A, and Lyeth BG. HDAC
Inhibitor Increases Histone H3 Acetylation and Reduces Microglia Inflammatory
Response Following Traumatic Brain Injury in Rats. Journal of Neurotrauma,
25(7); 932, 2008. Presented at the 26th
Annual National Neurotrauma Society
Symposium, Orlando, FL, July 27-30, 2008.
13. Mello PJ, Atkinson V, Lyeth BG and Gurkoff GG. Mechanical Strain Injury
Leads to Neuronal Dysfunction and Cell Death In Neuron-Astrocyte Co-Cultures
in the First Three Days Post-Injury. Journal of Neurotrauma, 26(8); A-85, 2009.
Presented at the Second Joint Symposium of the International and National
Neurotrauma Societies, Santa Barbara, CA Sept. 7-11, 2009.
14. Beller JA, Gurkoff GG, and Lyeth BG. Pharmacological Manipulation of
Astrocytic Glutamate Transporters, GLAST and GLT-1, Expression in
Neuron/Astrocyte Co-Cultures. Journal of Neurotrauma, 26(8); A-88, 2009.
Presented at the Second Joint Symposium of the International and National
Neurotrauma Societies, Santa Barbara, CA Sept. 7-11, 2009.
15. Gurkoff GG, Beller JA, Katleba KD and Lyeth BG. Elevated Extracellular K+
Reduces Accumulation of Ca2+
But Not Cell Death Following a Second Insult In-
Vitro. Journal of Neurotrauma, 26(8); A-19, 2009. Presented at the Second Joint
Symposium of the International and National Neurotrauma Societies, Santa
Barbara, CA Sept. 7-11, 2009.
16. Feng J, Gurkoff GG, Van K, West E, Lowe D, Lyeth, BG. NAAG Peptidase
Inhibitor PGI-02776 is Neuroprotective in a Model of Post-TBI Hypoxia. Journal
of Neurotrauma 27(5); A-65, 2010. Presented at the 28th
Annual National
Neurotrauma Society Symposium, Las Vegas, NV, June 14-17, 2010.
17. Beller JA, Gurkoff GG, Doisy E, Lyeth BG. Pharmacological Manipulation of
Glutamate Transporter Expression and Activity in Neuron/Astrocyte Cultures.
Journal of Neurotrauma 27(5); A-64, 2010. Presented at the 28th
Annual National
Neurotrauma Society Symposium, Las Vegas, NV, June 14-17, 2010.
18. Gurkoff GG, Shahlaie, Lyeth BG, Muizelaar JP, Berman RF. Delivery of a
VGCC Blocker through the Cisterna Magna Improves Cognitive Function in a
Rodent Model of Traumatic Brain Injury. Journal of Neurotrauma 28(5); A-56,
2011. Presented at the 10th
International Neurotrauma Meeting, Shanghai, CN,
April 27th
– May 1st, 2011.
19. Lee D, Gurkoff GG, Schwartzkroin P, Berman R, Muizelaar JP, Lyeth BG.
Hyperexcitability and Epileptogenesis Following Traumatic Brain Injury and
Secondary Hypoxia. Journal of Neurotrauma 28(5); A-60, 2011. Presented at the
10th
International Neurotrauma Meeting, Shanghai, CN, April 27th
– May 1st,
2011.
20. Zhang Z, Finger I, Gurkoff GG, Shabashvili A, Zoltewicz S, Wang KW.
Utilization of Fluorescently-Tagged Calpain and Caspase Inhibitors to Study
Necrotic and Apoptotic Neural Injury. Journal of Neurotrauma 28(5); A-58, 2011.
Presented at the 10th
International Neurotrauma Meeting, Shanghai, CN, April
27th
– May 1st, 2011.
21. Gurkoff GG, Van K, Izadi A, Feng J, Lowe D, Lyeth BG. Post-Treatment With
the NAAG Peptidase Inhibitor PGI-02776 Improves Functional Outcome
Following Moderate Lateral Fluid Percussion with Secondary Hypoxia. Journal of
Neurotrauma 28(6):A-77, 2011. Presented at the 29th
Annual National
Neurotrauma Society Symposium, Hollywood Beach, FL, July 10-13, 2011.
22. Lee D, Gurkoff GG, Izadi A, Schwartzkroin P, Berman R, Muizelaar JP,
Shahlaie K, Lyeth BG. Medial Septal Stimulation Following Traumatic Brain
Injury Increases Exploration. Journal of Neurotrauma 28(6):A-12, 2011.
Presented at the 29th
Annual National Neurotrauma Society Symposium,
Hollywood Beach, FL, July 10-13, 2011.
23. Zhang Z, Finger I, Gurkoff GG, Shabashvili A, Zoltewicz S, Wang KW.
Fluorescently Tagged Calpain and Caspase Inhibitors as Image Probes to Study
Necrotic and Apoptotic Neuro-Glial Injury. Journal of Neurotrauma 28(6):A-15,
2011. Presented at the 29th
Annual National Neurotrauma Society Symposium,
Hollywood Beach, FL, July 10-13, 2011.
24. Anagli J, Finger I, Gurkoff GG, Martinez J, Zhang Z, Wang KW, Larner S.
Neuron Specific NR-1 Targeted PLGA Nanoparticles. Journal of Neurotrauma
28(6):A-15, 2011. Presented at the 29th
Annual National Neurotrauma Society
Symposium, Hollywood Beach, FL, July 10-13, 2011.
25. Lee D, Gurkoff GG, Izadi A, Sonti AP, Schwartzkroin P, Berman R, Muizelaar
JP, Shahlaie K, Lyeth BG. Hippocampal Theta Perturbations After Traumatic
Brain Injury and Increased Exploration Following Medial Septal Stimulation.
Program 938.24 2011 Neuroscience Meeting Planner, Presented at the 41st Annual
Society for Neuroscience Meeting, Washington D.C. November 12-16, 2011.
26. Lee DJ. Gurkoff GG, Izadi A, Ekstrom A, Schwartzkroin P, Berman RF,
Muizelaar JP, Shahlaie K, Lyeth BG. Frequency-dependent effects of medial
septal stimulation for cognitive improvement following traumatic brain injury.
Journal of Neurotrauma 29:A-10, 2012. Presented at the 30th
National
Neurotrauma Symposium, Phoenix, AZ, July 22-25, 2012.
27. Cadena G, Lewis B, Bobinski M, Rudisill N, Gurkoff GG, Zwienenberg-Lee M,
Muizelaar JP, and Shahlaie K. Ct Scan Interpretation in TBI: Implications for
Resident Training. Journal of Neurotrauma 29:A-41, 2012. Presented at the 30th
National Neurotrauma Symposium, Phoenix, AZ, July 22-25, 2012.
28. Echeverri A, Gurkoff GG, Tesfasilassi T, Yin H, Lyeth BG, and Zwienenberg-
Lee M. Longitudinal Analysis of Behavioral Outcome Following Closed Skull
Injury in Post-Natal Day 35 Rats. Journal of Neurotrauma 29:A-101, 2012.
Presented at the 30th
National Neurotrauma Symposium, Phoenix, AZ, July 22-25,
2012.
29. Izadi I, Lee DJ, Gurkoff GG, Echeverri A, Schwartzkroin PA, Berman RF,
Muizelaar JP, Lyeth BG, and Shahlaie K. TBI leads to alterations in hippocampal
theta, beta and gamma frequencies during rest and exploration in rats. Journal of
Neurotrauma 29:A-111, 2012. Presented at the 30th
National Neurotrauma
Symposium, Phoenix, AZ, July 22-25, 2012.
30. Keachie K, Nishijima D, Utter G, Gurkoff GG, Zwienenberg-Lee M, Muizelaar
JP, and Shahlaie K. Impact of Direct Transport Versus Secondary Transfer on 6-
Month Outcome in Adult Patients with TBI. Journal of Neurotrauma 29:A-142,
2012. Presented at the 30th
National Neurotrauma Symposium, Phoenix, AZ, July
22-25, 2012.
31. Lee DJ, Shahlaie K, Izadi A, Melnik M, Seidl S, Berman RF, Ekstrom AD,
Muizelaar JP, Lyeth BG, Gurkoff GG. Stimulation of medial septum restores
hippocampal theta coherence following traumatic brain injury. Journal of
Neurotrauma 30(15): B-128, 2013. Presented at the 31st Annual National
Neurotrauma Symposium, Nashville, TN, August 4-7, 2013.
32. Madden L, Gurkoff GG, Shahlaie K, DeVon HA, Berman RF. Admission
Temperature does not Predict Extended Glasgow Outcome Scale Score following
Traumatic Brain Injury. Journal of Neurotrauma 30(15): A-132, 2013. Presented
at the 31st Annual National Neurotrauma Symposium, Nashville, TN, August 4-7,
2013.
33. Seidl SE, Izadi A, Lee DJ, Melnik M, Ekstrom AD, Shahlaie K, Gurkoff GG.
Stimulation of the Medial Septum Drives Hippocampal Theta Oscillations
Leading to Persistent Increases In Theta Phase Coherence. Journal of
Neurotrauma 31(12): A-98, 2014. Presented at the 32st Annual National
Neurotrauma Symposium, San Francisco, CA, June 29 – July 2nd, 2014.
34. Avitua A, Shafique H, Echeverri AM, Seidl SE, Yin H, Zwienenberg-Lee M,
Gurkoff GG. A New Rodent Model of Pediatric Sports-Related Concussion.
Journal of Neurotrauma 31(12): A-98, 2014. Presented at the 32st Annual
National Neurotrauma Symposium, San Francisco, CA, June 29 – July 2nd, 2014.
35. Huang S, Gurkoff GG, Garajehdaghi RJ, Tian L, Lyeth BG, Berman RF.
Blockade of the N-Type voltage-gated calcium channel reduces intracellular
calcium accumulation following injury visualized using the gene-encoded calcium
sensor GCaMP6. Program Number. 421.10/X11. 2014 Neuroscience Meeting
Planner. Presented at the 44th
Annual Society for Neuroscience Meeting,
Washington D.C. November 15-19, 2014.
36. Izadi A, Seidl S, Lee D, Ekstrom AD, Shahlaie K, Gurkoff GG. Medial septal
theta stimulation increases seizure threshold and improves cognition in a rat
model of epilepsy. Poster number 1.078, Page 38, 2014 American Epilepsy
Meeting Program. Presented at the 68th
Annual American Epilepsy Society
Meeting, Seattle, WA. December 5-9, 2014.
37. Berman RF, Huang S, Liew J, Lyeth BG, Tian L, Gurkoff GG. Calcium and
glutamate signaling after TBI visualized in-vitro using gene-encoded molecular
sensors GCaMP6 and iGluSnFR. Journal of Neurotrauma 32:A-1-A-152, 2015.
Presented at the 33rd
Annual National Neurotrauma Symposium, Santa Fe, NM,
June 28 – July 1, 2015.
38. Izadi A, Pevzner A, Huang S, Ekstrom AD, Cowen S, Shahlaie K, Gurkoff GG.
Medial temporal lobe epilepsy alters theta oscillations in animals behaving in a
spatial recognition memory task. Poster number 2.079, Page 60, 2015 American
Epilepsy Meeting Program. Presented at the 69th
Annual American Epilepsy
Society Meeting, Philadelphia, PA. December 4-8, 2015.
39. Pevzner A, Izadi A, Ekstrom AD, Shahlaie K, and Gurkoff GG. Network level
analysis of neural oscillations following fluid percussion injury in the rat. Journal
of Neurotrauma 33:A-1-A-139, 2016. Presented at the 34th
Annual National
Neurotrauma Symposium, Lexington, KY, June 26 – 29, 2016.
40. Tercovich K, Nord A, Zdilar I, Van K, Lyeth BG and Gurkoff GG. Longitudinal
gene expression analysis reveals systems-level perspective of TBI. Journal of
Neurotrauma 33:A-1-A-139, 2016. Presented at the 34th
Annual National
Neurotrauma Symposium, Lexington, KY, June 26 – 29, 2016.
41. Izadi A, Pevzner A, Ahmadpour A, Lee DJ, Ekstrom AD, Shahlaie K, Gurkoff
GG. Neuromodulatiuon to entrain oscillations increases seizure threshold and
improves cognition in the pilocarpine model of temporal lobe epilepsy. Poster
number 3.048, 2016 American Epilepsy Meeting Program. Presented at the 69th
Annual American Epilepsy Society Meeting, Houston, TX. December 2-6, 2016.
42. Ondek K, and Gurkoff GG. A new rat model of repeat mild traumatic brain
injury during adolescence. Journal of Neurotrauma 34:A-1-A-164, 2017.
Presented at the 35th
Annual National Neurotrauma Symposium, Snowbird, UT,
July 7 – 12, 2017.
43. Pevzner A, Gimlin K, Hernandez P, Izadi A, Ondek K, Shahlaie K, Gurkoff GG.
Deep brain stimulation to entrain theta oscillations and improve behavioral
outcome following lateral fluid percussion TBI. Journal of Neurotrauma 34:A-1-
A-164, 2017. Presented at the 35th
Annual National Neurotrauma Symposium,
Snowbird, UT, July 7 – 12, 2017.
44. Izadi A, Pevzner A, Ogbu-Nwobodo L, Shahlaie K and Gurkoff GG.
Neuromodulation of the septohippocampal network alters epileptogenesis
resulting in improved outcome in pilocarpine treated rats. Poster number 2.047,
2017 American Epilepsy Meeting Program. Presented at the 71st Annual
American Epilepsy Society Meeting, Washington D.C., December 1-5, 2017.
45. Ogbu-Nwobodo L, Izadi A, Pevzner A, Ahmadpour A, Shahlaie K and Gurkoff
GG. Low frequency vagal nerve stimulation to increase seizure threshold and
improve cognitive outcome in a rodent model of temporal lobe epilepsy. Poster
number 2.128, 2017 American Epilepsy Meeting Program. Presented at the 71st
Annual American Epilepsy Society Meeting, Washington D.C., December 1-5,
2017.
46. Binyamin T, Kamal K, Izadi I, Ondek K, Berman F, Sharp F, Gurkoff GG,
Waldau B. The effect of intraventricular hemorrhage injection in rats on spatial
memory and dentate neurogenesis. Poster number 475.21, Society for
Neuroscience Program. Presented at the 48th
Annual Society of Neuroscience
Meeting, San Diego, CA, November 3 – 7, 2018.
47. Izadi A, Ondek K, Schedlbauer A, Hsu E, Disse G, Shahlaie K and Gurkoff GG.
Stimulation of the medial septal nucleus reduces interictal spikes, entrains
oscillations, and improves object learning in epileptic rats. Poster number 3.109,
Page 42, 2018 American Epilepsy Meeting Program. Presented at the 72nd
Annual American Epilepsy Society Meeting, New Orleans, LA, November 30 –
December 4, 2018.
48. Ondek K, Izadi A, Schedlbauer A, Keselman I, Shahlaie K and Gurkoff GG.
Acute septal stimulation improves behavioral performance and seizure threshold
in pilocarpine-treated rats. Poster number 3.108, Page 42, 2018 American
Epilepsy Meeting Program. Presented at the 72nd
Annual American Epilepsy
Society Meeting, New Orleans, LA, November 30 – December 4, 2018.
Invited Talks
1. Neuromodulation to Treat Cognitive Dysfunction: Is One Target Enough? 15th
Annual University of California Neurotrauma Meeting, Carmel, California,
September 16th
, 2014.
2. Deep Brain Stimulation to Modulate Theta Oscillations and Improve Cognitive
Function Following Traumatic Brain Injury. 14th
Annual University of California
Neurotrauma Meeting, Santa Barbara, California, September 22th
, 2013.
3. Utility of Animal Models of Secondary Insult to Characterize Potential
Therapeutics. 12th
Annual University of California Neurotrauma Meeting, Santa
Barbara, California, September 25th
, 2011.
4. Applying Biophotonics to Neurotrauma. 8th
Annual University of California
Neurotrauma Meeting, Santa Barbara, California, September 24th, 2007.
5. Is the Developing Brain Vulnerable Following Traumatic Brain Injury?
University of California at Davis, Davis, CA, February 22nd
, 2005.
6. Gurkoff GG, Shin D, Reger M, Giza CC, R Sankar and Hovda DA. Concussive
Brain Injury Produces a State of Anatomical and Behavioral Preconditioning to
Seizures in the Developing Rat Brain. Journal of Neurotrauma, 22(10);1167,
2005. Presented at the 23rd
Annual National Neurotrauma Society Symposium,
Washington D.C., November 10-11, 2005.
7. Is the Developing Brain Vulnerable Following Traumatic Brain Injury? 7th
International Neurotrauma Symposium, Adelaide, Australia, September 16, 2004.
8. Traumatic Preconditioning in a Developmental TBI Model. 5th
Annual University
of California Neurotrauma Meeting, Carmel, California, August 19th
, 2004.
9. The Developing Story of Diffuse Traumatic Brain Injury In the Rat Pup. 4th
Annual University of California Neurotrauma Meeting, La Jolla, California,
August 22, 2003.
Oral Presentations
1. Brain Injury, Slow Wave Oscillations and Cognition. Spinal Cord and Brain
Injury Research Center, University of Kentucky, Lexington Kentucky, October
16th
2014.
2. Four Dimensional Imaging of Cells Undergoing Injury-Induced Cell Death.
Banyan Biomarkers Incorporated, Gainesville Florida, March 16th
2010.
3. Changes in the Extracellular Environment Influence Injury-Related Neuronal
Activity and Cell Death. Spinal Cord and Brain Injury Research Center,
University of Kentucky, Lexington Kentucky, May 14th
2009.
4. Post-Traumatic Neuronal Activity and Cell Death. Department of Biomedical
Engineering, New Jersey Institute of Technology, Newark NJ, March 26th
2009.
5. Can the Use of Advanced Optical Techniques Aid in Our Better Understanding of
Traumatic brain Injury? Center for Biophotonics and Science Technology
Summer Retreat, Squaw Valley, CA, July 17th
, 2007.
6. Chemically-Induced Status Epilepticus and the Post-Traumatic Brain: A
Characterization of Secondary Injury in the Immature Rat Brain. Center for
Biophotonics and Science Technology, University of California at Davis, Davis,
CA, September 8th
, 2006.
7. The Effect of Chemically-Induced Status Epilepticus and the Post-Traumatic
Brain: A Characterization of Secondary Injury in the Immature Rat Brain.
Burnham Institute for Medical Research, La Jolla CA, August 7th
, 2006.
8. Dysfunction in the Absence of Cell Death: Is the Developing Brain Vulnerable to
Secondary Insult Following Traumatic Brain Injury. Virginia Commonwealth
University, Richmond, VA, November 7th
, 2005.
SERVICE
NATIONAL SERVICE
National Neurotrauma Society
1. Social Media Committee 2016 - present
2. Program Committee 2016 – 2017
3. Program Committee 2018 - 2019
4. President of Teaching, Education, and Mentorship (TEAM) 2018 – present
Chair of A Scientific Session at a National Meeting
1. What we think we know: Different Perspectives. University of California 19th
Annual Neurotrauma Symposium, San Jose, CA, September 23-25th
, 2018.
2. Data Blitz A: Mini Presentations. 35th
Annual National Neurotrauma Symposium,
Snowbird, UT, July 7-12th
, 2017.
3. Big data and the future of TBI. University of California 18th
Annual Neurotrauma
Symposium, Santa Barbara, CA, September 24-26th
, 2017.
4. New technologies and ideas in neurotrauma. University of California 17th
Annual
Neurotrauma Symposium, Sonoma, CA, September 18-20th
, 2016.
5. Neurostimulation. University of California 15th
Annual Neurotrauma Symposium,
Carmel, CA, September 14-16th
, 2014.
6. Mild, Repeat TBI and Chronic Impairment. University of California 13th
Annual
Neurotrauma Symposium, Sonoma, CA, September 9-11th
, 2012.
Grant Review
Ad Hoc:
1. SRA International Inc 2016 - present
2. Paul J. Allen Family Foundation 2017
Service to Professional Publications
Referee:
1. Journal of Neurotrauma
2. Hippocampus
3. Behavioral Neuroscience
4. Glia
5. PLoS One
6. Epilepsy Research
7. Behavioral Brain Research
8. Neurobiology of Disease
9. Brain Research Bulletin
10. Journal of Neuorscience Research
11. Proceedings of the National Academy of Science
12. Epilepsy Research
13. Experimental Neurology
14. Journal of Neurosurgery
ACADEMIC SERVICE
Department of Neurological Surgery
1. Research Conference Coordinator 2016 - present
2. Search Committee (Chair) for new faculty in basic science 2017
Center for Neuroscience
1. Coordinator for Bootcamp Orientation 2015 - present
2. Space Committee 2015 - present
3. Qualifying Exam 1 Committee 2016 – 2017
4. Executive Committee 2017 – present
5. Advisory Committee 2017 – present
Graduate Student Committees
Qualifying Exams/Dissertation Proposal
1. Millie Copara 6/10/2014
2. Amber Shedlbauer 9/23/2015
3. Jared Stokes 4/6/2016
4. Rafael Veraza (external) 12/13/2016
5. John-Paul Aboubechara 3/17/2017
6. Jamie Kruger (chair) 1/19/2018
7. Brendon Cohn-Sheehy (chair) 3/14/2018
8. Kyle Ireton (chair) 7/18/2018
9. Preetham Ganupuru (chair) 7/30/2018
10. Lindsay Cameron (chair) 8/15/2018
11. Taylor Follansbee (chair) 10/17/2018
12. Stela Petkova (chair) 12/14/2018
13. Jonas Calsbeek 12/14/2018
Dissertation Committee
1. Amber Shedlbauer 2015 - 2018
2. Ali Izadi (chair) 2015 - 2018
3. Michelle Guignet 2017 – present
4. Jamie Krueger 2017 - present
5. Katelynn Ondek (chair) 2018 - present
6. Brendan Cohn-Sheehy 2018 - present
Masters Thesis Committee
1. Kayleen Terchovich (chair) 2016 – 2018
2. Thomas Salazar 2018
Service During Graduate School
1. Neuroscience IDP Committee (2004 – 2006). Served on a committee comprised
of 8 faculty members and 2 graduate students to evaluate, modify and implement
changes in the graduate program curricula and evaluations.
2. UCLA Graduate Students Association, Biological Sciences Committee (2001 –
2006). Represented the Neuroscience IDP program on the Biological Sciences
Committee. Discussed issues and concerns of graduate students in our program
as they related to University mandates, programs and benefits.
3. UCLA Graduate Students Association Forum Representative (2005-2006)).
Served as the Biological Sciences Committee representative to the Graduate
Students Association Forum (a forum comprised of representatives from 13
different councils representing all graduate and professional students at UCLA).
4. Neuroscience Admissions Committee (2002). Organized all events for two
recruitment weekends. Coordinated faculty, students and recruits for interviews,
social events and transportation.
ONGOING RESEARCH SUPPORT
Title (Source) Effort Fund Period Costs
1R01NS084026 (PI: Gurkoff)
NIH, NINDS 45% 2/1/14-1/31/19 $2,075,000
Restoring Connectivity Following Traumatic Brain Injury
The major goal of this grant is to evaluate changes in electrical activity across the
septohippocampal circuit following traumatic brain injury and to evaluate the
potential of deep brain stimulation as a therapeutic option.
Role: Principle Investigator
2R01NS076856 (PI: Ekstrom; Univ. of Arizona)7/15/18 – 4/30/23
NIH, NINDS 5% $275,000
Representation of spatiotemporal information in human episodic memory and
navigation
The major goal of this project is to evaluate the role of oscillations in spatial learning
and cognition using stereo EEG or depth electrodes and/or cortical grids in epilepsy
patients as a part of their medical course of care to treat refractory epilepsy.
Role: Principle Investigator on the UC Davis subaward
UC Davis (PI: Shahlaie) 0% 7/1/18 – 6/30/19 $50,000
Comprehensive Cancer Center
Intracranial Electrode Implantation to Deliver Spherical Tumor Treatment Fields
Therapy for Management of Glioblastoma Multiforme
The major goal of this program is to use neurostimulation techniques to create an
electric field around and ultimately eliminate, brain tumors.
Role: Co-Investigator
PENDING RESEARCH SUPPORT
Title (Source) Effort Fund Period Costs
1R01NS112496 (PI: Gurkoff)
NIH, NINDS 35% 8/1/19 – 7/31/24 $2,375,000
Altered synchrony: a mechanism for seizures and cognitive decline
The major goal of this program is to evaluate and manipulate neural synchrony in
epileptic rats in order to better define mechanisms related to seizures and cognitive
dysfunction in epilepsy.
Role: Principle Investigator
W81XWH-18-ERP (PI: Martin)
CDMRP/DoD 0% 7/1/19 – 6/30/21 $300,000
Imaging of Glial Activation and Risk of Post-Traumatic Epilepsy
The major goal of this study is to use a novel PET probe for TSPO to determine
whether there is a correlation between post-traumatic glial activity and the
development of post-traumatic epilepsy in patients following moderate-to-severe TBI.
COMPLETED RESEARCH SUPPORT
Pediatric TBI and Cognition (PI: Zwienenberg-Lee)
Children’s Miracle Network 25% 7/1/12-6/30/14 $50,000
Grant #CMNMZ12
Novel Mechanism for Reducing Acute and Chronic Neurodegeneration after
Traumatic Brain Injury (PI: Lyeth)
DoD 5% 1/1/14-12/31/16 $496,050
Grant #PT120075
Mapping Human Memory with Electrocorticography and Chronometric Stimulation
(PI: Ekstrom)
NIH, NINDS 5% 9/30/14 – 8/31/16 $366,160
1R21NS087527
PROFESSIONAL SOCIETY MEMBERSHIPS
2007 – present National Neurotrauma Society
2009 – present Society for Neurosciences
2014 – present American Epilepsy Society
HONORS
2018 UC Davis Neuroscience Graduate Group: Outstanding Graduate
Mentor in Neuroscience Award
2018 UC Davis Neuroscience Graduate Faculty: Outstanding Service
Award
2011 International Neurotrauma Society Student Travel Award
2009 Above and Beyond Award for outstanding contributions to the
Education efforts at the University of California Davis, NSF
Center for Biophotonics Science & Technology.
2008 Above and Beyond Award for outstanding contributions to the
Education efforts at the University of California Davis, NSF
Center for Biophotonics Science & Technology.
2005 National Neurotrauma Society Alan Faden Award of Excellence
for top abstract and poster presentation at the Annual National
Neurotrauma Society Meeting
2004 International Neurotrauma Society Student Travel Award