CURRICULUM VITAE GENE GABRIEL GURKOFF · CURRICULUM VITAE GENE GABRIEL GURKOFF EDUCATION 2006 Ph.D....

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CURRICULUM VITAE GENE GABRIEL GURKOFF EDUCATION 2006 Ph.D. in Neuroscience, Laboratory of Dr. David Hovda, Neuroscience Interdepartmental Program, University of California Los Angeles, Los Angeles, CA 1998 B.S., Honors, in Neuroscience, Brown University, Providence, RI RESEARCH INTERESTS My primary research interests are in evaluating mechanisms and developing innovative treatments for traumatic brain injury and epilepsy patients. Currently the field of traumatic brain injury focuses primarily on developing neuroprotective compounds to reduce cell death following injury. The majority of epilepsy research is related to reducing seizures. However, patients with traumatic brain injury and epilepsy both present with a range of behavioral disorders, with cognitive disability being a common co-morbidity. There are currently minimal efforts to develop innovative therapies to improve cognition in chronic TBI and epilepsy patients. My laboratory uses animal models of traumatic brain injury and epilepsy to better understand the physiological and anatomical basis for chronic cognitive and social deficits in both the pediatric and adult rat. Our current focus is on using advanced in vivo electrophysiology techniques to identify systems-level changes in brain function with the goal of developing novel and innovative neuromodulatory approaches for treating patients suffering chronic cognitive deficits related to traumatic brain injury or epilepsy. Our ultimate goal is to translate these innovative treatment strategies from the bench to the bedside. RESEARCH EXPERIENCE 2018 present Director of UC Davis Neurological Surgery Research Laboratory 2014 present Assistant Professor, Department of Neurological Surgery, University of California Davis, Davis, CA. 2012 - 2014 Assistant Professional Researcher, Department of Neurological Surgery, University of California Davis, Davis, CA. 2007 - 2012 Postdoctoral Fellow, Department of Neurological Surgery, University of California Davis, Davis, CA. Advisor Dr. Bruce Lyeth 2010 - 2011 Post-Doctoral Fellow, Banyan Biomarkers Inc, Gainesville, FL 2006 2007 Postdoctoral Fellow, Department of Surgery, Division of Neurosurgery, University of California Los Angeles, Los Angeles, CA. Advisor: Dr. Richard Sutton, 1998 2000 Staff Research Associate II, Laboratory of Dr. Allen Basbaum, Department of Anatomy, University of California San Francisco, San Francisco, CA

Transcript of CURRICULUM VITAE GENE GABRIEL GURKOFF · CURRICULUM VITAE GENE GABRIEL GURKOFF EDUCATION 2006 Ph.D....

Page 1: CURRICULUM VITAE GENE GABRIEL GURKOFF · CURRICULUM VITAE GENE GABRIEL GURKOFF EDUCATION 2006 Ph.D. in Neuroscience, Laboratory of Dr. David Hovda, ... 2012 - 2015 Haroon Shafique,

CURRICULUM VITAE

GENE GABRIEL GURKOFF

EDUCATION

2006 Ph.D. in Neuroscience, Laboratory of Dr. David Hovda,

Neuroscience Interdepartmental Program, University of California

Los Angeles, Los Angeles, CA

1998 B.S., Honors, in Neuroscience, Brown University, Providence, RI

RESEARCH INTERESTS

My primary research interests are in evaluating mechanisms and developing innovative

treatments for traumatic brain injury and epilepsy patients. Currently the field of

traumatic brain injury focuses primarily on developing neuroprotective compounds to

reduce cell death following injury. The majority of epilepsy research is related to

reducing seizures. However, patients with traumatic brain injury and epilepsy both

present with a range of behavioral disorders, with cognitive disability being a common

co-morbidity. There are currently minimal efforts to develop innovative therapies to

improve cognition in chronic TBI and epilepsy patients. My laboratory uses animal

models of traumatic brain injury and epilepsy to better understand the physiological and

anatomical basis for chronic cognitive and social deficits in both the pediatric and adult

rat. Our current focus is on using advanced in vivo electrophysiology techniques to

identify systems-level changes in brain function with the goal of developing novel and

innovative neuromodulatory approaches for treating patients suffering chronic cognitive

deficits related to traumatic brain injury or epilepsy. Our ultimate goal is to translate

these innovative treatment strategies from the bench to the bedside.

RESEARCH EXPERIENCE

2018 – present Director of UC Davis Neurological Surgery Research Laboratory

2014 – present Assistant Professor, Department of Neurological Surgery,

University of California Davis, Davis, CA.

2012 - 2014 Assistant Professional Researcher, Department of Neurological

Surgery, University of California Davis, Davis, CA.

2007 - 2012 Postdoctoral Fellow, Department of Neurological Surgery,

University of California Davis, Davis, CA. Advisor Dr. Bruce

Lyeth

2010 - 2011 Post-Doctoral Fellow, Banyan Biomarkers Inc, Gainesville, FL

2006 – 2007 Postdoctoral Fellow, Department of Surgery, Division of

Neurosurgery, University of California Los Angeles, Los Angeles,

CA. Advisor: Dr. Richard Sutton,

1998 – 2000 Staff Research Associate II, Laboratory of Dr. Allen Basbaum,

Department of Anatomy, University of California San Francisco,

San Francisco, CA

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1996 – 1998 Undergraduate Research Assistant, Laboratory of Dr. J. Michael

Walker, Brown University, Providence, RI

1996 – 1997 Summer Intern, Connectics Inc., Palo Alto, CA

TEACHING EXPERIENCE

2018 Instructor of Record NSC298 Rocks and Shoals. A career

development course for neuroscience graduate students. Invited 9

guest speakers with either expertise in career development or who

had chosen careers outside of academia to meet with graduate

students and led discussions. (10 weeks, 1 hour/week)

2018 Instructor of Record NSC271C Translational Approaches to

Learning, Memory, and Plasticity Disorders. I developed the

curriculum of the course to focus around three disease areas per 10

weeks of instruction. In successive weeks the clinical condition

was discussed followed by strategies for in vivo and then in vitro

research respectively. (10 weeks, 2 hours/week)

2017 Instructor PTX 203 Principles of Pharmacology and Toxicology

III. Graduate level class. Included traditional instruction (2 hours)

pertaining to neurotransmitters with a subsequent case study (1

hour)

2017 Instructor of Record FRS 003 007 Neurobiology of Learning

(Freshman seminar). Small group based instruction. Co-taught

with my post doctoral fellow Dr. Alex Pevzner (10 weeks, 1

hour/week)

2017 - present Instructor VMB 234 Current Topics in Neurotoxicology.

Graduate level course. Lectured on excitotoxicity (1 hr).

2017 Instructor NSC298 Rocks and Shoals. A career development

course for neuroscience graduate students. Discussed “two body

problem” and how to develop a 2 and 5 min research pitch (2

weeks, 1 hour/week)

2016 - present Instructor of Record FRS 003 027 Brain stimulation (Freshman

seminar). Small group based instruction (10 weeks, 1 hour/week)

2016 - 2017 Instructor and Mentor First Year Aggie Connection. This was a

discussion section offered to incoming community college transfer

students aimed to develop balance and a routine in their daily

schedule (10 hrs)

2016 - present Instructor NSC 201 Neuroanatomy. Graduate level course.

Lectured on the anatomy of the cerebellum (1 hr)

2015 Instructor Doctoring AMP 1 (School of Medicine). Small group

case-based instruction (6 hrs). Topic: Chronic obstructive

pulmonary disease.

2014 Instructor Doctoring AMP 1 (School of Medicine). Small group

case-based instruction (6 hrs). Topic: Lead poisoning.

2010 Instructor and Mentor (winter internship), Winter Internship for

Community College Students (CC Winter; 100 hours), Helped to

implement and supervise a two-week intensive laboratory course.

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Prepared and presented three lectures (30 minutes each), Center of

Biophotonics Science and Technology at UC Davis, Jan 4-15th

2010.

2009 - 2011 Instructor (summer internship), Summer Internship for the Center

of Biophotonics at UC Davis. Proposed, designed and led a

Neuroscience and Biophotonics Journal Club (5 hours/week)

2009 - 2011 Organizer and Instructor, Summer Internship for the Center of

Biophotonics at UC Davis June 15 - 20. Assisted in the design and

implementation of a one-week intensive program (40 hours)

2009 Instructor and Mentor (winter internship), Winter Internship for

Community College Students (CCWinter; 15 hours), Center of

Biophotonics Science and Technology at UC Davis, Jan 5-16,

2009

2009 - present Instructor Basic Science (neurosurgical residents), Department of

Neurological Surgery, UC Davis School of Medicine (2-5 hours

annually). Lectures include: anatomy, plasticity, excitotoxicity,

neuromodulation.

2008 - 2013 Instructor, IST 8A (freshman course), Integrated Studies,

Invitational Honors Program, Introduction to Biophotonics (1.5

hours). Lecture: Applying the Scientific Method to Biophotonics.

2008 – 2009, 2012 Instructor, EAD/BIM 289 (graduate course), Selected Topics in

Biophotonics (2 hours). Lecture: Applying Biophotonics to CNS

Injury.

2001 and 2002 Teaching Assistant, Neuroanatomy 102 (undergraduate course),

Department of Neuroscience, David Geffen School of Medicine at

UCLA, Los Angeles, CA (10 weeks). Supervised weekly labs,

held weekly office hours (2 hrs/week), prepared and taught one

review session (10 hrs).

Other Teaching Experience

2012 – 2017 Mentor. University of Davis, California Alliance for Minority

Participation (CAMP) program. This program is designed to

present opportunities in research for under-represented and

economically disadvantaged students who have an interest in

pursuing a graduate degree (4 total students).

2012 – present Mentor. Biology Undergraduate Scholars Program (BUSP) –

Honors. This program is designed to present opportunities in

research for under-represented and economically disadvantaged

students who have an interest in pursuing a graduate degree. I give

annual presentations on lab etiquette as well as a basic science

lecture to the entire class. In addition I mentor individual students

within the program (5 total students, 2 active).

2012 Mentor. Mentorship for Undergraduate Research in Agriculture,

Letters and Science (MURALS). This program is designed to

present opportunities in research for under-represented and

economically disadvantaged (1 former student).

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2007 – 2013 Mentor. Center for Biophotonics Science and Technology

Internship. This program is designed to present opportunities in

research for under-represented and economically disadvantaged

who are pursuing a career in medicine or research (13 former

students).

2013 - present Moderator. Moderate an oral presentation session at the annual

Undergraduate Research Conference (URC).

RESEARCH MENTORING EXPERIENCE

Postdoctoral Fellows

2018 – present Ali Izadi. Received a PhD in neuroscience from UC Davis

2018 – present Amber Schedlbauer. Received a PhD in neuroscience from UC

Davis.

2015 - 2017 Alexzander Pevzner. Received a PhD in neuroscience from UC

Irvine. Currently an Assistant Professor at Notre Dame de Namur

University.

Neurosurgery Residents

2017 – 2018 Tamar Binyamin. Currently chief resident in UC Davis

Neurological Surgery residency program. Received her MD from

Virginia Commonwealth University.

2018 – 2019 Amir Goodarzi. Received his MD from UC Davis.

Graduate Students

2016 - present Katelynn Ondek a dual degree student in the Department of

Veterinary Medicine and the UC Davis Neuroscience Graduate

Group

2016 - 2018 Kayleen Tercovich a member of the UC Davis Neuroscience

Graduate Group. Received her masters degree in Spring 2018.

Currently employed by The Jackson Laboratories.

2013 - present Ali Izadi, a member of the UC Davis Neuroscience Graduate

Group. Currently a post-doctoral fellow in my lab.

2010 – 2012 Darrin Lee, a member of the UC Davis Neuroscience Graduate

Group and Neurosurgery Resident. Currently an Assistant

Professor in Neurosurgery at University of Southern California.

Medical Students

2016 – 2017 Lucy Ogbu-Nwobodo. A T32 scholar between 3rd

and 4th

year of

medical school. Currently in a Psychiatry residency program at

Harvard University.

2015 – 2016 Arjang Ahmandpour. A T32 scholar between 3rd

and 4th

year of

medical school. Currently in a Neurosurgical residency program at

University of Chicago.

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Rotating Graduate Students

2016 Brendan Cohn-Sheehy. Currently in his 3rd

year of Neuroscience

Graduate School.

2018 Gregory Disse. Currently a MS2 in medical school.

Undergraduate

2019 – present Francisco Valverde, a UC Davis Undergraduate (6 hrs/week)

2018 – present Myat Wai, a UC Davis Undergraduate (6 hrs/week)

2018 – present Consuelo Jimenez-Ornelas, a UC Davis Undergraduate (8

hrs/week)

2017 – present Olga Brevnova, a UC Davis Undergraduate (8 hrs/week).

2016 - 2017 Pedro Hernandez, a UC Davis Undergraduate (10 hrs/week).

2016 - 2017 Matthew Culberson, a UC Davis Undergraduate (3 hrs/week).

2015 - 2018 Emily Hsu, a UC Davis Undergraduate (6 hrs/week)

2014 and 2015 Anthony Fong, summer intern from the UC Santa Cruz (25

hrs/week). Currently a technician in the Dr. Edward Chang lab at

UCSF.

2014 and 2015 Abby Scurfield, summer intern from the University of Puget Sound

(25 hrs/week). Current position unknown.

2014 - 2016 Sunny Yu, a UC Davis undergraduate (10 hrs/week). Current

position unknown.

2014 - 2017 Eman Meky, a UC Davis undergraduate (10 hrs/week) and CAMP

Summer Program (32 hrs/week). Recently graduated and studying

for the MCAT.

2013 - 2016 Lauren Ekman, a UC Davis undergraduate (6 hrs/week). Recently

completed a masters degree program at USC.

2013 Fritz Libby, a undergraduate at California State University,

Northridge, and Minority Biomedical Research Support / Research

Initiative for Scientific Enhancement Intern (40 hrs/week for 10

weeks). Current position unknown.

2012 - 2015 Mikhail Melnik, a UC Davis undergraduate (10 hrs/week), and UC

Davis Center for Biophontonics Science and Technology Summer

Intern (35 hrs/week for 12 weeks). Currently a neuroscience

graduate student at UCLA.

2012 - 2015 Rafael Ordaz, a UC Davis undergraduate (10 hrs/week) and UC

Davis Center for Biophotonics and Science and Technology

Summer Intern (35 .hrs/week for 12 weeks). Current position

unknown

2012 - 2015 Angela Avitua, a UC Davis undergraduate (8 hrs/week) and UC

Davis Center for Biophotonics and Science and Technology.

Summer Intern (35 hrs/week for 12 weeks). Currently a

neuroscience graduate student at University of California,

Riverside.

2012 - 2015 Haroon Shafique, a UC Davis undergraduate (8 hrs/week) and UC

Davis Center for Biophotonics and Science and Technology

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Summer Intern (35 hrs/week for 12 weeks). Currently employed at

Genentech.

2012 Laura Brouchard, a UC Davis undergraduate (6 hrs/week for 1

quarter). Currently a second year medical student at UCSF.

2012 Hunter Trice, a UC Davis undergraduate (2011 – 2012 (6 hrs/week

for 2 quarters). Current position unknown

2012 Simon Chang, a UC Davis undergraduate (6 hrs/week for 2

quarters). Current position unknown

2011 - 2014 Nick Yin, a UC Davis undergraduate (8 hrs/week). Current

position unknown

2011 - 2014 Anup Sonti, a UC Davis undergraduate (6 hrs/week). Currently a

first year medical student at Hofstra Northwell School of

Medicine.

2011 - 2012 Heather McConnell, a UC Davis undergraduate (8 hrs/week).

Received her PhD from Oregon Health Sciences and is currently a

post-doctoral scholar.

2011 - 2013 Rebecca Wong, a UC Davis undergraduate (6 hrs/week). Currently

employed by Genentech.

2011 - 2014 Tomas Tesfasilassie, a UC Davis undergraduate (10 hrs/week) and

UC Davis Center for Biophotonics and Science and Technology

Summer Intern (35 hrs/week for 12 weeks). Currently in medical

school at UCSF.

2010 - 2011 Andrea Domingo, a UC Davis undergraduate (8 hrs/week). Current

position unknown

2010 - 2011 Jennifer Gahan, a UC Davis undergraduate (8 hrs/week).

Currently a PGY2 resident in Surgery at University of North

Carolina.

2010 - 2013 Rahil Ghiasvand, a UC Davis undergraduate (8-12 hrs/week) and

UC Davis Center for Biophotonics and Science and Technology

Summer Intern (35 hrs/week for 12 weeks). Currently enrolled in

the Marine Science and Watershed Systems Masters Program at

California State University, Monterey.

2010 & 2011 M. Hiram Dominguez, a University of Santa Barbara

undergraduate. UC Davis Center for Biophotonics and Science

Technologies Summer Intern (35 hrs/week for 12 weeks and 2

summers). Currently employed as a laboratory technician at UC

Merced.

2010 Carissa Perez, a University of San Diego undergraduate. UC Davis

Center for Biophotonics and Science Technologies Summer Intern

(35 hrs/week for 10 weeks). Current position unknown.

2008 – 2010 Vanessa Atkinson, a UC Davis undergraduate (6-8 hrs/week) and

UC Davis Center for Biophotonics and Science and Technology

Summer Intern (35 hrs/week for 12 weeks). Currently a charge

nurse at the Palo Alto VA.

2008 - 2010 Paul Mello, UC Davis undergraduate (6 hrs/week) and UC Davis

Center for Biophotonics and Science and Technology Summer

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Intern (35 hrs/week for 12 weeks). Currently an In-Hospital

Pharmacist at Kaiser Oakland Medical Center.

2008 & 2009 Justiss Kallos, an Emory University Undergraduate. UC Davis

Center for Biophotonics and Science Technologies summer intern

(35 hrs/week for 10 weeks). Currently a 4th

year medical student at

Vanderbilt.

2007 & 2008 Bryan Brandon, a California State San Louis Obispo

undergraduate. UC Davis Center for Biophotonics and Science

Technologies summer intern (35 hrs/week for 12 weeks and 2

summers). Currently a PGY4 in a Head and Neck Surgery

Residency Program at University of North Carolina.

2007 Cristal Resto, Solano College undergraduate. UC Davis Center for

Biophotonics and Science Technologies summer intern (35

hrs/week for 12 weeks). Current position unknown.

High School

2019 Amanda Soeth, a student at Davis Highschool. Amanda

participated in a 70 hr internship (Jan – May) as a part of her high

school biotechnology class.

2019 Jessica Bennett, a student at Davis Highschool. Jessica participated

in a 70 hr internship (Jan – May) as a part of her high school

biotechnology class.

2018 Jillian Fahey, a student at Davis Highschool. Jilian participated in a

70 hr internship (Jan – May) as a part of her high school

biotechnology class.

PEER-REVIEWED PUBLICATIONS

1. Gurkoff GG, Giza CC, Hovda DA. Lateral Fluid Percussion Injury in the

Developing Rat Causes An Acutre, Mild Behavioral Dysfunction in the Absence

of Significant Cell Death. Brain Research 1077(1); 24-36, 2006.

2. Myer DJ, Gurkoff GG, Norton D, Lee SM, Hovda DA, and Sofroniew MV.

Essential Protective Roles of Reactive Astrocytes in Traumatic Brain Injury.

Brain 129(Pt 10); 2761-2772, 2006.

3. Zhang B, West EJ, Van KC, Gurkoff GG, Zhou J, Zhang X-M, Kozikowski AP,

Lyeth BG. HDAC Inhibitor Increases Histone H3 Acetylation and Reduces

Microglia Inflammatory Response Following Traumatic Brain Injury in Rats.

Brain Research 1226; 181-191, 2008.

4. Gurkoff GG, Shin D, Auvin S, Sankar R, Hovda DA. Acute Neuroprotection to

Pilocarpine-Induced Seizures is Not Sustained After Traumatic Brain Injury in the

Developing Rat. Neuroscience 164(2); 862-876, 2009

5. Shahlaie K, Lyeth BG, Gurkoff GG, Muizelaar JP, Berman RF. Neuroprotective

Effects of Selective N-Type VGCC Blockade on Stretch Injury-Induced Calcium

Dynamics in Cortical Neurons. J Neurotrauma 27(1); 175-187, 2010.

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6. Feng J, Van KC, Gurkoff GG, Kopriva C, Song M, Yuen P, Jiang J, Zhou J,

Lyeth BG. Post-injury administration of NAAG peptidase inhibitor prodrug, PGI-

02776, in experimental TBI. Brain Research 1395; 62-73, 2011.

7. Beller JA, Gurkoff GG, Berman RF and Lyeth BG. Pharmacological

Enhancement of Glutamate Transport Reduces Excitotoxicity. Restorative

Neurology and Neuroscience 29(5); 331-346, 2011.

8. Feng J*, Zhao, X*, Gurkoff GG, Van KC, Shahlaie K, and Lyeth BG.

Posttraumatic Hypoxia Exacerbates Neuronal Cell Death in the Hippocampus J

Neurotrauma 29(6); 1167-1179, 2012.

9. Gurkoff GG, Shahlaie K, and Lyeth BG. In vitro mechanical strain trauma alters

neuronal calcium responses: Implications for posttraumatic epilepsy. Epliepsia

53(suppl.1); 53-60, 2012.

10. Feng J, Gurkoff GG, Van KC, Song M, Lowe DA, Zhou J, and Lyeth BG.

NAAG Peptidase Inhibitor Reduces Cellular Damage in a Model of TBI with

Secondary Hypoxia. Brain Research 1469; 144-152, 2012.

11. Lee DJ, Gurkoff GG, Izadi A, Berman RF, Ekstrom AD, Muizelaar JP, Lyeth

BG and Shahlaie K. Medial septal nucleus theta frequency deep brain stimulation

improves spatial working memory after traumatic brain injury. J Neurotrauma

30(2); 131-139, 2013.

12. Gurkoff GG, Gahan JD, Ghiasvand RT, Hunsaker MR, Van K, Feng JF, Shahlaie

K, Berman RF, Lyeth BG, and Folkerts MM. Evaluation of metric, topological

and temporal ordering memory tasks after lateral fluid percussion injury. J

Neurotrauma 30(4); 292-300, 2013.

13. Shahlaie K*, Gurkoff GG*, Lyeth BG, Muizelaar JP, and Berman RF.

Neuroprotective effects of SNX-185 in an in vitro model of TBI with a second

insult. Restorative Neurology and Neuroscience 31(2); 141-153, 2013.

14. Watrous AJ*, Lee DJ*, Izadi A, Gurkoff GG, Shahlaie K, and Ekstrom AD. A

comperative study of human and rat hippocampal low frequency oscillations

during spatial navigation. Hippocampus 23(8); 656-661, 2013.

15. Gurkoff GG, Feng JF, Van KC, Izadi A, Ghiasvand RT, Shahlaie K, Song M,

Lowe DA, Zhou J, and Lyeth BG. NAAG peptidase inhibitor improves motor

function and reduces cognitive dysfunction in a model of TBI with secondary

hypoxia. Brain Res 1515; 98-107, 2013.

16. Gurkoff GG, Shahlaie K, Lyeth BG, and Berman RF. Voltage-Gated Calcium

Channel Antagonists and Traumatic Brain Injury (Review). Pharmaceuticals 6(7);

788-812, 2013.

17. Lee DJ, Gurkoff GG, Goodarzi A, Muizelaar JP, Boggan JE, and Shahlaie K.

Intracerebroventricular opiate infusion for refractory head and facial pain. World

Journal of Clinical Cases 2(8); 351-356, 2014.

18. Lee DJ, Gurkoff GG, Izadi A, Echeverri A, Melnik M, Berman RF, Ekstrom AD,

Muizelaar JP, Lyeth BG, and Shahlaie K. Hippocampal theta frequency

modulation for cognitive and electrophysiological improvement following

traumatic brain injury. J Neurotrauma 32(22); 1822-1832, 2015.

19. Kolarik BS, Shahlaie K, Hassan A, Borders AA, Kaufman KC, Gurkoff GG,

Yonelinas AP, and Ekstrom AD. Impairments in precision, rather than spatial

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strategy, characterize performance on the virtual Morris Water Maze; A case

study. Neuropsychologia 80; 90-101, 2015.

20. Pevzner A, Izadi A, Lee DJ, Shahlaie K, and Gurkoff GG. Making Waves in the

Brain: What Are Oscillations, and Why Modulating Them Makes Sense for Brain

Injury (Review). Front Syst Neurosci. 2016.

21. Lee DJ, Izadi A, Melnik M, Seidl S, Echeverri A, Shahlaie K, and Gurkoff GG.

Stimulation of the medial septum improves performance in spatial learning

following pilocarpine-induced status epilepticus. Epilepsy Res. 130; 53-63, 2017.

22. Scangos KW, Carter CS, Zhang L, Gurkoff GG, and Shahlaie K. Theta

frequency stimulation of the subthalamic nucleus improves cognitive dysfunction

in Parkinson’s disease. Brain Stimulation. 11(2); 456-458, 2018.

23. Izadi A*, Ondek K*, Schedlbauer A, Keselman I, Shahlaie K, and Gurkoff GG.

Clinically Indicated Electrical Stimulation Strategies to Treat Patients with

Medically Refractory Epilepsy Open. 2018.

24. Izadi A, Pevzner A, Lee DJ, Ekstrom A, Shahlaie K, and Gurkoff GG. Medial

septal nucleus stimulation increases seizure threshold and improves cognitive

function in a rodent model of temporal lobe epilepsy. Brain Stimulation (in press)

Submitted

1. Moxon K, Shahlaie K, Girgis F, Saez I, and Gurkoff GG. From adagio to

allegretto: The changing tempo of theta frequencies in epilepsy and its relation to

interneuron function. (submitted to Neurobiology of Disease; November 2018)

In Preparation

1. Izadi A, Ondek K, Schedlbauer A, Ekstrom AD, Shahlaie K and Gurkoff GG.

Theta stimulation of the medial septum during epileptogenesis reduces seizures

and improves cognitive outcome.

2. Ondek K*, Pevzner A*, Tercovich K*, Izadi I, Schedlbauer A, Ekstrom AD,

Cowen S, Shahlaie K and Gurkoff GG. Traumatic brain injury results in

depressed oscillations across the septohippocampal circuit.

ABSTRACTS AND PRESENTATIONS

Poster Presentations:

1. Malmberg A, Gurkoff GG, Gilbert H, Zhou L-M, McCabe T, Basbaum AI.

Antinociceptive Effects of Cone Snail Venom-Derived Subtype-Selective

NMDA-Receptor Antagonists. Society for Neuroscience, 25:921, 1999.

Presented at the 29th

Annual Society for Neuroscience Meeting, Miami, FL,

October 23-28, 1999.

2. Gurkoff GG, Wagstaff JD, Layer RT, McCabe T, Basbaum AI. Antinociceptive

Effects of Spinal Contulakin-G, A Cone Snail-Derived Neurotensin. Society for

Neuroscience Annual Meetings Abstracts Volume (26), 2000. Presented at the

30th

Annual Society for Neuroscience Meeting, New Orleans, LA, November 4-9,

2000.

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3. Trafton JA, Gurkoff, GG, Basbaum AI. Consequences of Mu Opiod Receptor

(MOR) Internalization for Morphine-Induced Analgesia and Tolerance. Society

for Neuroscience Annual Meetings Abstracts Volume (27) 2001. Presented at the

31st Annual Society for Neuroscience Meeting, San Diego, CA, November 10-15,

2001.

4. Gurkoff GG, Giza CC, Hovda DA. Behavioral Deficits Following Lateral Fluid

Percussion Injury in the Rat Pup Due to Cellular Dysfunction and Not Cell Death.

Journal of Neurotrauma, 19(10);1320, 2002. Presented at the 20th

Annual National

Neurotrauma Society Symposium, Tampa, FL and the 6th

International

Neurotrauma Symposium, October 27 – November 1, 2002.

5. Gurkoff GG, Hoffmann JR, Giza CC, Hovda DA. Injury Severity Does Not

Predict Outcome in a Model of Developmental Lateral Fluid Percussion. Journal

of Neurotrauma 20(10);1093, 2003. Presented at the 21st Annual National

Neurotrauma Society Symposium, Biloxi, MS, November 6-7, 2003.

6. Gurkoff GG, Shin D, Reger M, Giza CC, Sankar R, Hovda DA. Lateral Fluid

Percussion Sustained Early in Life Protects Hippocampal Cells from Secondary

Seizure. Journal of Neurotrauma, 21(9);1341, 2004. Presented at the 22th

Annual

National Neurotrauma Society Symposium, San Diego, CA, October 21-22, 2004.

7. Gurkoff GG, Shin D, Giza CC, Hovda DA, and Sankar R. Concussive Brain

Injury Produces a State of Preconditioning in the Developing Rat Brain. Annals

of Neurology, 58(S9); S115, 2005. Presented at the 34th

Child Neurology Society

Annual Meeting, Los Angeles, CA, September 28 – October 1, 2005.

8. Reger ML, Gurkoff GG, Hovda DA, and Giza CC. The Novel Object

Recognition Task Detects a Transient Cognitive Deficit After Developmental

TBI. Journal of Neurotrauma, 22(10);1206, 2005. Presented at the 23rd

Annual

National Neurotrauma Society Symposium, Washington D.C., November 10-11,

2005.

9. Gurkoff GG, Shin D, Auvin S, Giza CC, Sankar R, and Hovda DA. Concussive

Brain Injury and Status Epilepticus: Acute Preconditioning Does Not Translate to

Long-Term Hippocampal Protection From Seizures. Journal of Neurotrauma,

23(6); 1031, 2006. Presented at the 24th

Annual National Neurotrauma Society

Symposium, St. Louis, MO, July 7-9, 2006.

10. Hutson C, Gurkoff GG, Giza CC, Hovda DA, and Chesselet MF. Multiple Risk

Factors for Parkinson’s Disease: Pesticide Exposure and Traumatic Brain Injury.

Journal of Neurotrauma, 24(7); 1232, 2007 Presented at the 25th

Annual National

Neurotrauma Society Symposium, Kansas City, MO, July 30-Aug 1, 2007.

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11. Gurkoff GG, Katleba KD, Justin JA, and Lyeth BG. Changes in Extracellular

Potassium Influence Injury-Related Neuronal Activity and Cell Death. Journal of

Neurotrauma, 25(7); 926, 2008. Presented at the 26th

Annual National

Neurotrauma Society Symposium, Orlando, FL, July 27-30, 2008.

12. Zhang B, West E, Van K, Gurkoff GG, Kozikowski A, and Lyeth BG. HDAC

Inhibitor Increases Histone H3 Acetylation and Reduces Microglia Inflammatory

Response Following Traumatic Brain Injury in Rats. Journal of Neurotrauma,

25(7); 932, 2008. Presented at the 26th

Annual National Neurotrauma Society

Symposium, Orlando, FL, July 27-30, 2008.

13. Mello PJ, Atkinson V, Lyeth BG and Gurkoff GG. Mechanical Strain Injury

Leads to Neuronal Dysfunction and Cell Death In Neuron-Astrocyte Co-Cultures

in the First Three Days Post-Injury. Journal of Neurotrauma, 26(8); A-85, 2009.

Presented at the Second Joint Symposium of the International and National

Neurotrauma Societies, Santa Barbara, CA Sept. 7-11, 2009.

14. Beller JA, Gurkoff GG, and Lyeth BG. Pharmacological Manipulation of

Astrocytic Glutamate Transporters, GLAST and GLT-1, Expression in

Neuron/Astrocyte Co-Cultures. Journal of Neurotrauma, 26(8); A-88, 2009.

Presented at the Second Joint Symposium of the International and National

Neurotrauma Societies, Santa Barbara, CA Sept. 7-11, 2009.

15. Gurkoff GG, Beller JA, Katleba KD and Lyeth BG. Elevated Extracellular K+

Reduces Accumulation of Ca2+

But Not Cell Death Following a Second Insult In-

Vitro. Journal of Neurotrauma, 26(8); A-19, 2009. Presented at the Second Joint

Symposium of the International and National Neurotrauma Societies, Santa

Barbara, CA Sept. 7-11, 2009.

16. Feng J, Gurkoff GG, Van K, West E, Lowe D, Lyeth, BG. NAAG Peptidase

Inhibitor PGI-02776 is Neuroprotective in a Model of Post-TBI Hypoxia. Journal

of Neurotrauma 27(5); A-65, 2010. Presented at the 28th

Annual National

Neurotrauma Society Symposium, Las Vegas, NV, June 14-17, 2010.

17. Beller JA, Gurkoff GG, Doisy E, Lyeth BG. Pharmacological Manipulation of

Glutamate Transporter Expression and Activity in Neuron/Astrocyte Cultures.

Journal of Neurotrauma 27(5); A-64, 2010. Presented at the 28th

Annual National

Neurotrauma Society Symposium, Las Vegas, NV, June 14-17, 2010.

18. Gurkoff GG, Shahlaie, Lyeth BG, Muizelaar JP, Berman RF. Delivery of a

VGCC Blocker through the Cisterna Magna Improves Cognitive Function in a

Rodent Model of Traumatic Brain Injury. Journal of Neurotrauma 28(5); A-56,

2011. Presented at the 10th

International Neurotrauma Meeting, Shanghai, CN,

April 27th

– May 1st, 2011.

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19. Lee D, Gurkoff GG, Schwartzkroin P, Berman R, Muizelaar JP, Lyeth BG.

Hyperexcitability and Epileptogenesis Following Traumatic Brain Injury and

Secondary Hypoxia. Journal of Neurotrauma 28(5); A-60, 2011. Presented at the

10th

International Neurotrauma Meeting, Shanghai, CN, April 27th

– May 1st,

2011.

20. Zhang Z, Finger I, Gurkoff GG, Shabashvili A, Zoltewicz S, Wang KW.

Utilization of Fluorescently-Tagged Calpain and Caspase Inhibitors to Study

Necrotic and Apoptotic Neural Injury. Journal of Neurotrauma 28(5); A-58, 2011.

Presented at the 10th

International Neurotrauma Meeting, Shanghai, CN, April

27th

– May 1st, 2011.

21. Gurkoff GG, Van K, Izadi A, Feng J, Lowe D, Lyeth BG. Post-Treatment With

the NAAG Peptidase Inhibitor PGI-02776 Improves Functional Outcome

Following Moderate Lateral Fluid Percussion with Secondary Hypoxia. Journal of

Neurotrauma 28(6):A-77, 2011. Presented at the 29th

Annual National

Neurotrauma Society Symposium, Hollywood Beach, FL, July 10-13, 2011.

22. Lee D, Gurkoff GG, Izadi A, Schwartzkroin P, Berman R, Muizelaar JP,

Shahlaie K, Lyeth BG. Medial Septal Stimulation Following Traumatic Brain

Injury Increases Exploration. Journal of Neurotrauma 28(6):A-12, 2011.

Presented at the 29th

Annual National Neurotrauma Society Symposium,

Hollywood Beach, FL, July 10-13, 2011.

23. Zhang Z, Finger I, Gurkoff GG, Shabashvili A, Zoltewicz S, Wang KW.

Fluorescently Tagged Calpain and Caspase Inhibitors as Image Probes to Study

Necrotic and Apoptotic Neuro-Glial Injury. Journal of Neurotrauma 28(6):A-15,

2011. Presented at the 29th

Annual National Neurotrauma Society Symposium,

Hollywood Beach, FL, July 10-13, 2011.

24. Anagli J, Finger I, Gurkoff GG, Martinez J, Zhang Z, Wang KW, Larner S.

Neuron Specific NR-1 Targeted PLGA Nanoparticles. Journal of Neurotrauma

28(6):A-15, 2011. Presented at the 29th

Annual National Neurotrauma Society

Symposium, Hollywood Beach, FL, July 10-13, 2011.

25. Lee D, Gurkoff GG, Izadi A, Sonti AP, Schwartzkroin P, Berman R, Muizelaar

JP, Shahlaie K, Lyeth BG. Hippocampal Theta Perturbations After Traumatic

Brain Injury and Increased Exploration Following Medial Septal Stimulation.

Program 938.24 2011 Neuroscience Meeting Planner, Presented at the 41st Annual

Society for Neuroscience Meeting, Washington D.C. November 12-16, 2011.

26. Lee DJ. Gurkoff GG, Izadi A, Ekstrom A, Schwartzkroin P, Berman RF,

Muizelaar JP, Shahlaie K, Lyeth BG. Frequency-dependent effects of medial

septal stimulation for cognitive improvement following traumatic brain injury.

Journal of Neurotrauma 29:A-10, 2012. Presented at the 30th

National

Neurotrauma Symposium, Phoenix, AZ, July 22-25, 2012.

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27. Cadena G, Lewis B, Bobinski M, Rudisill N, Gurkoff GG, Zwienenberg-Lee M,

Muizelaar JP, and Shahlaie K. Ct Scan Interpretation in TBI: Implications for

Resident Training. Journal of Neurotrauma 29:A-41, 2012. Presented at the 30th

National Neurotrauma Symposium, Phoenix, AZ, July 22-25, 2012.

28. Echeverri A, Gurkoff GG, Tesfasilassi T, Yin H, Lyeth BG, and Zwienenberg-

Lee M. Longitudinal Analysis of Behavioral Outcome Following Closed Skull

Injury in Post-Natal Day 35 Rats. Journal of Neurotrauma 29:A-101, 2012.

Presented at the 30th

National Neurotrauma Symposium, Phoenix, AZ, July 22-25,

2012.

29. Izadi I, Lee DJ, Gurkoff GG, Echeverri A, Schwartzkroin PA, Berman RF,

Muizelaar JP, Lyeth BG, and Shahlaie K. TBI leads to alterations in hippocampal

theta, beta and gamma frequencies during rest and exploration in rats. Journal of

Neurotrauma 29:A-111, 2012. Presented at the 30th

National Neurotrauma

Symposium, Phoenix, AZ, July 22-25, 2012.

30. Keachie K, Nishijima D, Utter G, Gurkoff GG, Zwienenberg-Lee M, Muizelaar

JP, and Shahlaie K. Impact of Direct Transport Versus Secondary Transfer on 6-

Month Outcome in Adult Patients with TBI. Journal of Neurotrauma 29:A-142,

2012. Presented at the 30th

National Neurotrauma Symposium, Phoenix, AZ, July

22-25, 2012.

31. Lee DJ, Shahlaie K, Izadi A, Melnik M, Seidl S, Berman RF, Ekstrom AD,

Muizelaar JP, Lyeth BG, Gurkoff GG. Stimulation of medial septum restores

hippocampal theta coherence following traumatic brain injury. Journal of

Neurotrauma 30(15): B-128, 2013. Presented at the 31st Annual National

Neurotrauma Symposium, Nashville, TN, August 4-7, 2013.

32. Madden L, Gurkoff GG, Shahlaie K, DeVon HA, Berman RF. Admission

Temperature does not Predict Extended Glasgow Outcome Scale Score following

Traumatic Brain Injury. Journal of Neurotrauma 30(15): A-132, 2013. Presented

at the 31st Annual National Neurotrauma Symposium, Nashville, TN, August 4-7,

2013.

33. Seidl SE, Izadi A, Lee DJ, Melnik M, Ekstrom AD, Shahlaie K, Gurkoff GG.

Stimulation of the Medial Septum Drives Hippocampal Theta Oscillations

Leading to Persistent Increases In Theta Phase Coherence. Journal of

Neurotrauma 31(12): A-98, 2014. Presented at the 32st Annual National

Neurotrauma Symposium, San Francisco, CA, June 29 – July 2nd, 2014.

34. Avitua A, Shafique H, Echeverri AM, Seidl SE, Yin H, Zwienenberg-Lee M,

Gurkoff GG. A New Rodent Model of Pediatric Sports-Related Concussion.

Journal of Neurotrauma 31(12): A-98, 2014. Presented at the 32st Annual

National Neurotrauma Symposium, San Francisco, CA, June 29 – July 2nd, 2014.

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35. Huang S, Gurkoff GG, Garajehdaghi RJ, Tian L, Lyeth BG, Berman RF.

Blockade of the N-Type voltage-gated calcium channel reduces intracellular

calcium accumulation following injury visualized using the gene-encoded calcium

sensor GCaMP6. Program Number. 421.10/X11. 2014 Neuroscience Meeting

Planner. Presented at the 44th

Annual Society for Neuroscience Meeting,

Washington D.C. November 15-19, 2014.

36. Izadi A, Seidl S, Lee D, Ekstrom AD, Shahlaie K, Gurkoff GG. Medial septal

theta stimulation increases seizure threshold and improves cognition in a rat

model of epilepsy. Poster number 1.078, Page 38, 2014 American Epilepsy

Meeting Program. Presented at the 68th

Annual American Epilepsy Society

Meeting, Seattle, WA. December 5-9, 2014.

37. Berman RF, Huang S, Liew J, Lyeth BG, Tian L, Gurkoff GG. Calcium and

glutamate signaling after TBI visualized in-vitro using gene-encoded molecular

sensors GCaMP6 and iGluSnFR. Journal of Neurotrauma 32:A-1-A-152, 2015.

Presented at the 33rd

Annual National Neurotrauma Symposium, Santa Fe, NM,

June 28 – July 1, 2015.

38. Izadi A, Pevzner A, Huang S, Ekstrom AD, Cowen S, Shahlaie K, Gurkoff GG.

Medial temporal lobe epilepsy alters theta oscillations in animals behaving in a

spatial recognition memory task. Poster number 2.079, Page 60, 2015 American

Epilepsy Meeting Program. Presented at the 69th

Annual American Epilepsy

Society Meeting, Philadelphia, PA. December 4-8, 2015.

39. Pevzner A, Izadi A, Ekstrom AD, Shahlaie K, and Gurkoff GG. Network level

analysis of neural oscillations following fluid percussion injury in the rat. Journal

of Neurotrauma 33:A-1-A-139, 2016. Presented at the 34th

Annual National

Neurotrauma Symposium, Lexington, KY, June 26 – 29, 2016.

40. Tercovich K, Nord A, Zdilar I, Van K, Lyeth BG and Gurkoff GG. Longitudinal

gene expression analysis reveals systems-level perspective of TBI. Journal of

Neurotrauma 33:A-1-A-139, 2016. Presented at the 34th

Annual National

Neurotrauma Symposium, Lexington, KY, June 26 – 29, 2016.

41. Izadi A, Pevzner A, Ahmadpour A, Lee DJ, Ekstrom AD, Shahlaie K, Gurkoff

GG. Neuromodulatiuon to entrain oscillations increases seizure threshold and

improves cognition in the pilocarpine model of temporal lobe epilepsy. Poster

number 3.048, 2016 American Epilepsy Meeting Program. Presented at the 69th

Annual American Epilepsy Society Meeting, Houston, TX. December 2-6, 2016.

42. Ondek K, and Gurkoff GG. A new rat model of repeat mild traumatic brain

injury during adolescence. Journal of Neurotrauma 34:A-1-A-164, 2017.

Presented at the 35th

Annual National Neurotrauma Symposium, Snowbird, UT,

July 7 – 12, 2017.

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43. Pevzner A, Gimlin K, Hernandez P, Izadi A, Ondek K, Shahlaie K, Gurkoff GG.

Deep brain stimulation to entrain theta oscillations and improve behavioral

outcome following lateral fluid percussion TBI. Journal of Neurotrauma 34:A-1-

A-164, 2017. Presented at the 35th

Annual National Neurotrauma Symposium,

Snowbird, UT, July 7 – 12, 2017.

44. Izadi A, Pevzner A, Ogbu-Nwobodo L, Shahlaie K and Gurkoff GG.

Neuromodulation of the septohippocampal network alters epileptogenesis

resulting in improved outcome in pilocarpine treated rats. Poster number 2.047,

2017 American Epilepsy Meeting Program. Presented at the 71st Annual

American Epilepsy Society Meeting, Washington D.C., December 1-5, 2017.

45. Ogbu-Nwobodo L, Izadi A, Pevzner A, Ahmadpour A, Shahlaie K and Gurkoff

GG. Low frequency vagal nerve stimulation to increase seizure threshold and

improve cognitive outcome in a rodent model of temporal lobe epilepsy. Poster

number 2.128, 2017 American Epilepsy Meeting Program. Presented at the 71st

Annual American Epilepsy Society Meeting, Washington D.C., December 1-5,

2017.

46. Binyamin T, Kamal K, Izadi I, Ondek K, Berman F, Sharp F, Gurkoff GG,

Waldau B. The effect of intraventricular hemorrhage injection in rats on spatial

memory and dentate neurogenesis. Poster number 475.21, Society for

Neuroscience Program. Presented at the 48th

Annual Society of Neuroscience

Meeting, San Diego, CA, November 3 – 7, 2018.

47. Izadi A, Ondek K, Schedlbauer A, Hsu E, Disse G, Shahlaie K and Gurkoff GG.

Stimulation of the medial septal nucleus reduces interictal spikes, entrains

oscillations, and improves object learning in epileptic rats. Poster number 3.109,

Page 42, 2018 American Epilepsy Meeting Program. Presented at the 72nd

Annual American Epilepsy Society Meeting, New Orleans, LA, November 30 –

December 4, 2018.

48. Ondek K, Izadi A, Schedlbauer A, Keselman I, Shahlaie K and Gurkoff GG.

Acute septal stimulation improves behavioral performance and seizure threshold

in pilocarpine-treated rats. Poster number 3.108, Page 42, 2018 American

Epilepsy Meeting Program. Presented at the 72nd

Annual American Epilepsy

Society Meeting, New Orleans, LA, November 30 – December 4, 2018.

Invited Talks

1. Neuromodulation to Treat Cognitive Dysfunction: Is One Target Enough? 15th

Annual University of California Neurotrauma Meeting, Carmel, California,

September 16th

, 2014.

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2. Deep Brain Stimulation to Modulate Theta Oscillations and Improve Cognitive

Function Following Traumatic Brain Injury. 14th

Annual University of California

Neurotrauma Meeting, Santa Barbara, California, September 22th

, 2013.

3. Utility of Animal Models of Secondary Insult to Characterize Potential

Therapeutics. 12th

Annual University of California Neurotrauma Meeting, Santa

Barbara, California, September 25th

, 2011.

4. Applying Biophotonics to Neurotrauma. 8th

Annual University of California

Neurotrauma Meeting, Santa Barbara, California, September 24th, 2007.

5. Is the Developing Brain Vulnerable Following Traumatic Brain Injury?

University of California at Davis, Davis, CA, February 22nd

, 2005.

6. Gurkoff GG, Shin D, Reger M, Giza CC, R Sankar and Hovda DA. Concussive

Brain Injury Produces a State of Anatomical and Behavioral Preconditioning to

Seizures in the Developing Rat Brain. Journal of Neurotrauma, 22(10);1167,

2005. Presented at the 23rd

Annual National Neurotrauma Society Symposium,

Washington D.C., November 10-11, 2005.

7. Is the Developing Brain Vulnerable Following Traumatic Brain Injury? 7th

International Neurotrauma Symposium, Adelaide, Australia, September 16, 2004.

8. Traumatic Preconditioning in a Developmental TBI Model. 5th

Annual University

of California Neurotrauma Meeting, Carmel, California, August 19th

, 2004.

9. The Developing Story of Diffuse Traumatic Brain Injury In the Rat Pup. 4th

Annual University of California Neurotrauma Meeting, La Jolla, California,

August 22, 2003.

Oral Presentations

1. Brain Injury, Slow Wave Oscillations and Cognition. Spinal Cord and Brain

Injury Research Center, University of Kentucky, Lexington Kentucky, October

16th

2014.

2. Four Dimensional Imaging of Cells Undergoing Injury-Induced Cell Death.

Banyan Biomarkers Incorporated, Gainesville Florida, March 16th

2010.

3. Changes in the Extracellular Environment Influence Injury-Related Neuronal

Activity and Cell Death. Spinal Cord and Brain Injury Research Center,

University of Kentucky, Lexington Kentucky, May 14th

2009.

4. Post-Traumatic Neuronal Activity and Cell Death. Department of Biomedical

Engineering, New Jersey Institute of Technology, Newark NJ, March 26th

2009.

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5. Can the Use of Advanced Optical Techniques Aid in Our Better Understanding of

Traumatic brain Injury? Center for Biophotonics and Science Technology

Summer Retreat, Squaw Valley, CA, July 17th

, 2007.

6. Chemically-Induced Status Epilepticus and the Post-Traumatic Brain: A

Characterization of Secondary Injury in the Immature Rat Brain. Center for

Biophotonics and Science Technology, University of California at Davis, Davis,

CA, September 8th

, 2006.

7. The Effect of Chemically-Induced Status Epilepticus and the Post-Traumatic

Brain: A Characterization of Secondary Injury in the Immature Rat Brain.

Burnham Institute for Medical Research, La Jolla CA, August 7th

, 2006.

8. Dysfunction in the Absence of Cell Death: Is the Developing Brain Vulnerable to

Secondary Insult Following Traumatic Brain Injury. Virginia Commonwealth

University, Richmond, VA, November 7th

, 2005.

SERVICE

NATIONAL SERVICE

National Neurotrauma Society

1. Social Media Committee 2016 - present

2. Program Committee 2016 – 2017

3. Program Committee 2018 - 2019

4. President of Teaching, Education, and Mentorship (TEAM) 2018 – present

Chair of A Scientific Session at a National Meeting

1. What we think we know: Different Perspectives. University of California 19th

Annual Neurotrauma Symposium, San Jose, CA, September 23-25th

, 2018.

2. Data Blitz A: Mini Presentations. 35th

Annual National Neurotrauma Symposium,

Snowbird, UT, July 7-12th

, 2017.

3. Big data and the future of TBI. University of California 18th

Annual Neurotrauma

Symposium, Santa Barbara, CA, September 24-26th

, 2017.

4. New technologies and ideas in neurotrauma. University of California 17th

Annual

Neurotrauma Symposium, Sonoma, CA, September 18-20th

, 2016.

5. Neurostimulation. University of California 15th

Annual Neurotrauma Symposium,

Carmel, CA, September 14-16th

, 2014.

6. Mild, Repeat TBI and Chronic Impairment. University of California 13th

Annual

Neurotrauma Symposium, Sonoma, CA, September 9-11th

, 2012.

Grant Review

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Ad Hoc:

1. SRA International Inc 2016 - present

2. Paul J. Allen Family Foundation 2017

Service to Professional Publications

Referee:

1. Journal of Neurotrauma

2. Hippocampus

3. Behavioral Neuroscience

4. Glia

5. PLoS One

6. Epilepsy Research

7. Behavioral Brain Research

8. Neurobiology of Disease

9. Brain Research Bulletin

10. Journal of Neuorscience Research

11. Proceedings of the National Academy of Science

12. Epilepsy Research

13. Experimental Neurology

14. Journal of Neurosurgery

ACADEMIC SERVICE

Department of Neurological Surgery

1. Research Conference Coordinator 2016 - present

2. Search Committee (Chair) for new faculty in basic science 2017

Center for Neuroscience

1. Coordinator for Bootcamp Orientation 2015 - present

2. Space Committee 2015 - present

3. Qualifying Exam 1 Committee 2016 – 2017

4. Executive Committee 2017 – present

5. Advisory Committee 2017 – present

Graduate Student Committees

Qualifying Exams/Dissertation Proposal

1. Millie Copara 6/10/2014

2. Amber Shedlbauer 9/23/2015

3. Jared Stokes 4/6/2016

4. Rafael Veraza (external) 12/13/2016

5. John-Paul Aboubechara 3/17/2017

6. Jamie Kruger (chair) 1/19/2018

7. Brendon Cohn-Sheehy (chair) 3/14/2018

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8. Kyle Ireton (chair) 7/18/2018

9. Preetham Ganupuru (chair) 7/30/2018

10. Lindsay Cameron (chair) 8/15/2018

11. Taylor Follansbee (chair) 10/17/2018

12. Stela Petkova (chair) 12/14/2018

13. Jonas Calsbeek 12/14/2018

Dissertation Committee

1. Amber Shedlbauer 2015 - 2018

2. Ali Izadi (chair) 2015 - 2018

3. Michelle Guignet 2017 – present

4. Jamie Krueger 2017 - present

5. Katelynn Ondek (chair) 2018 - present

6. Brendan Cohn-Sheehy 2018 - present

Masters Thesis Committee

1. Kayleen Terchovich (chair) 2016 – 2018

2. Thomas Salazar 2018

Service During Graduate School

1. Neuroscience IDP Committee (2004 – 2006). Served on a committee comprised

of 8 faculty members and 2 graduate students to evaluate, modify and implement

changes in the graduate program curricula and evaluations.

2. UCLA Graduate Students Association, Biological Sciences Committee (2001 –

2006). Represented the Neuroscience IDP program on the Biological Sciences

Committee. Discussed issues and concerns of graduate students in our program

as they related to University mandates, programs and benefits.

3. UCLA Graduate Students Association Forum Representative (2005-2006)).

Served as the Biological Sciences Committee representative to the Graduate

Students Association Forum (a forum comprised of representatives from 13

different councils representing all graduate and professional students at UCLA).

4. Neuroscience Admissions Committee (2002). Organized all events for two

recruitment weekends. Coordinated faculty, students and recruits for interviews,

social events and transportation.

ONGOING RESEARCH SUPPORT

Title (Source) Effort Fund Period Costs

1R01NS084026 (PI: Gurkoff)

NIH, NINDS 45% 2/1/14-1/31/19 $2,075,000

Restoring Connectivity Following Traumatic Brain Injury

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The major goal of this grant is to evaluate changes in electrical activity across the

septohippocampal circuit following traumatic brain injury and to evaluate the

potential of deep brain stimulation as a therapeutic option.

Role: Principle Investigator

2R01NS076856 (PI: Ekstrom; Univ. of Arizona)7/15/18 – 4/30/23

NIH, NINDS 5% $275,000

Representation of spatiotemporal information in human episodic memory and

navigation

The major goal of this project is to evaluate the role of oscillations in spatial learning

and cognition using stereo EEG or depth electrodes and/or cortical grids in epilepsy

patients as a part of their medical course of care to treat refractory epilepsy.

Role: Principle Investigator on the UC Davis subaward

UC Davis (PI: Shahlaie) 0% 7/1/18 – 6/30/19 $50,000

Comprehensive Cancer Center

Intracranial Electrode Implantation to Deliver Spherical Tumor Treatment Fields

Therapy for Management of Glioblastoma Multiforme

The major goal of this program is to use neurostimulation techniques to create an

electric field around and ultimately eliminate, brain tumors.

Role: Co-Investigator

PENDING RESEARCH SUPPORT

Title (Source) Effort Fund Period Costs

1R01NS112496 (PI: Gurkoff)

NIH, NINDS 35% 8/1/19 – 7/31/24 $2,375,000

Altered synchrony: a mechanism for seizures and cognitive decline

The major goal of this program is to evaluate and manipulate neural synchrony in

epileptic rats in order to better define mechanisms related to seizures and cognitive

dysfunction in epilepsy.

Role: Principle Investigator

W81XWH-18-ERP (PI: Martin)

CDMRP/DoD 0% 7/1/19 – 6/30/21 $300,000

Imaging of Glial Activation and Risk of Post-Traumatic Epilepsy

The major goal of this study is to use a novel PET probe for TSPO to determine

whether there is a correlation between post-traumatic glial activity and the

development of post-traumatic epilepsy in patients following moderate-to-severe TBI.

COMPLETED RESEARCH SUPPORT

Pediatric TBI and Cognition (PI: Zwienenberg-Lee)

Children’s Miracle Network 25% 7/1/12-6/30/14 $50,000

Grant #CMNMZ12

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Novel Mechanism for Reducing Acute and Chronic Neurodegeneration after

Traumatic Brain Injury (PI: Lyeth)

DoD 5% 1/1/14-12/31/16 $496,050

Grant #PT120075

Mapping Human Memory with Electrocorticography and Chronometric Stimulation

(PI: Ekstrom)

NIH, NINDS 5% 9/30/14 – 8/31/16 $366,160

1R21NS087527

PROFESSIONAL SOCIETY MEMBERSHIPS

2007 – present National Neurotrauma Society

2009 – present Society for Neurosciences

2014 – present American Epilepsy Society

HONORS

2018 UC Davis Neuroscience Graduate Group: Outstanding Graduate

Mentor in Neuroscience Award

2018 UC Davis Neuroscience Graduate Faculty: Outstanding Service

Award

2011 International Neurotrauma Society Student Travel Award

2009 Above and Beyond Award for outstanding contributions to the

Education efforts at the University of California Davis, NSF

Center for Biophotonics Science & Technology.

2008 Above and Beyond Award for outstanding contributions to the

Education efforts at the University of California Davis, NSF

Center for Biophotonics Science & Technology.

2005 National Neurotrauma Society Alan Faden Award of Excellence

for top abstract and poster presentation at the Annual National

Neurotrauma Society Meeting

2004 International Neurotrauma Society Student Travel Award