Creating the University of the Highlands and Islands Department of Diabetes & Cardiovascular Science...

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Creating the University of the Highlands and Islands

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Department of Diabetes &

Cardiovascular Science

HI STOPHI STOPHiHighland ghland SSchoolschools DiabeDiabetteses

PreventiPreventioonn PProgrammerogramme

Sandra MacRuryDept of Diabetes & Cardiovascular Science

UHI Millennium InstituteInverness

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“Diabetes is the greatest health challenge facing

the UK today”

Diabetes UK 2007

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Diabetes epidemic

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Pancreas

Brain

Liver

Stomach

Intestines

Pancreas

INSULIN

ISLET

Cell

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Types of Diabetes

• Type 1 15%

• Type 2 85%

World Health Organisation 2005

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Type 1 Diabetes

• Destruction of insulin producing cells

( cells in pancreas)

• Children, young people up to 35-40 years

• Late onset Type 1 > 40 years

• 10-15% occurs in families

• Treated with insulin

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What is diabetes

• The body cannot effectively use the insulin it produces • Middle aged or older 40+ years• Young onset type 2 < 35 years• 40% occurs in families• Treated with diet, tablets and sometimes insulin

World Health Organisation 2006

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Type 2 diabetes

• WeightWeight• Family Family history history • Age Age • EthnicityEthnicity

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Type 2 diabetes

• WeightWeight• WaistWaist circumferencecircumference• Family Family history history • Age Age • EthnicityEthnicity

+

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What Diabetes Epidemic?

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BMI

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T2DM and weight

0

2

4

6

8

10

12

14

18.5 or under 18.5 to 25 25 to 30 30 to 40 Over 40

BMI (kg/m2)

Pre

vale

nce

of

Typ

e 2

dia

be

tes

(%)

MaleFemale

Body Mass Index BMIWeight/height

Kg/m2

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Vascular problems in diabetes

75%

LIFE EXPECTANCY

SHORTENED

7-8 YEARS

IN T2DM

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Progression of Type 2 diabetes

Adapted from Bailey. Br J Cardiol 2000; 7: 350–360DeFronzo & Ferrannini. Diabetes Care 1991; 14: 173–194

Insulin resistance

Blood glucose

Insulin production

Normal Pre diabetes Type 2 diabetes

Diagnosis

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What can we do?

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Watch what you eat

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Get active!