UCSC MS bioinformatics report 2010
Novel multi-platform next generation assembly methods for mammalian genomes The Baylor College of Medicine, Australian Government and University of Connecticut.
Transcriptome analysis With a reference – Challenging due to size and complexity of datasets – Many tools available, driven by biomedical research – GATK.
Novel multi-platform next generation assembly methods for mammalian genomes
Informatics for next-generation sequence analysis – SNP calling
Transcriptome analysis
Allele Specific Gene/Isoform Expression
Experimental Setup Whole brain RNA-Seq Data from Sanger Institute Mouse Genomes Project [Keane et al. 2011] Synthetic hybrids with different levels.