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1 MEDIA LAB ASIA CRAFT REVIVAL PROJECT INDIAN INSTITUTE OF TECHNOLOGY KANPUR KANPUR.
Regulatory Motifs. Contents Biology of regulatory motifs Experimental discovery Computational discovery PSSM MEME.
Sequence motifs. What are sequence motifs? Sequences are translated into electron densities with different affinities of interacting with other molecules.
Sequence Motifs. Motifs Motifs represent a short common sequence –Regulatory motifs (TF binding sites) –Functional site in proteins (DNA binding motif)
Biological Motif Discovery Concepts Motif Modeling and Motif Information EM and Gibbs Sampling Comparative Motif Prediction Applications Transcription.
Motif Finding PSSMs Expectation Maximization Gibbs Sampling.
