LINKAGE ANALYSIS. Recombination Fraction During synapsis, crossing-over may occur between any two non-sister chromatids If there are allelic differences.
Linkage Chromosome mapping by recombination Meiosis is the basis of transmission genetics The recombination that occurs during meiosis (in heterozygotes)
. Introduction to Gene Mapping Techniques Lecture 2 This class has been edited from several sources. Primarily from Terry Speed’s homepage at Stanford.
Discovering Disease Genes- The Example of Schizophrenia Pippa Thomson, Medical Genetics Section, Dept of Medical Sciences, MMC, University of Edinburgh.