Nature Genetics 37, 77 - 83 (2004) Modular epistasis in yeast metabolism Daniel Segr � 1, Alexander DeLuna2, George M Church1 & Roy Kishony2.
ASSIGNING GENE FUNCTION BY EXPERIMENTAL ANALYSIS 1.Gene inactivation (loss-of-function) - mutate gene (“knock-out”) and observe change in phenotype (i)Deletion.
ASSIGNING GENE FUNCTION BY EXPERIMENTAL ANALYSIS
