8/18/2019 USMLE Diseases
1/9
Wolf’s Amnesia A transient selective loss of memory during an exam that prevents onefrom remembering the eponymically-named diseases discovered by old, dead doctors.
Addison’s Disease • primary adrenocortical deficiency
Addisonian Anemia • pernicious anemia (antibodies to intrinsic factor or parietal cells → ↓I → ↓!it "#$ → megaloblastic anemia%
Albright’s &yndrome • polyostotic fibrous dysplasia, precocious puberty, caf' au lait spots, short stature, young girls
Alport’s &yndrome • hereditary nephritis ith nerve deafness
Al)heimer’s • progressive dementiaArgyll-*obertson +upil • loss of light reflex constriction (contralateral or bilateral%
• +rostitute’s ye - accommodates but does not react• +athognomonic for /°&yphilis
Arnold-0hiari 1alformation • cerebellar tonsil herniation
"arrett’s • columnar metaplasia of loer esophagus ( ris2 of adenocarcinoma%
"artter’s &yndrome • hyperreninemia
"ec2er’s 1uscular Dystrophy • similar to Duchenne, but less severe (deficiency in dystrophin protein%
"ell’s +alsy • 03!II palsy (entire face4 recall that 513 lesion only affects loer face%
"erger’s Disease • IgA nephropathy
"ernard-&oulier Disease • defect in platelet adhesion (abnormally large platelets 6 lac2 of platelet-surface glycoprotein%
"erry Aneurysm • circle of Willis (subarachnoid bleed%•
often associated ith AD+7D"oen’s Disease • carcinoma in situ on shaft of penis ( ris2 of visceral ca%
"ri8uet’s &yndrome • somati)ation disorder• psychological9 multiple physical complaints ithout physical pathology
"roca’s Aphasia • 1otor Aphasia intact comprehension
"ron-&e8uard • hemisection of cord (contralateral loss of pain 6 temp : ipsilateral loss of fine touch, 513%
"ruton’s Disease • ;-lin2ed agammaglobinemia
"udd-0hiari • post-hepatic venous thrombosis
"uerger’s Disease • acute inflammation of small, medium arteries → painful ischemia → gangrene
"ur2itt’s
8/18/2019 USMLE Diseases
2/9
hler’s-Danlos • defective collagen
isenmenger’s 0omplex • late cyanotic shunt (*→
8/18/2019 USMLE Diseases
3/9
+aget’s Disease • abnormal bone architecture (thic2ened, numerous fractures → pain%
+ancoast ?umor • bronchogenic tumor ith superior sulcus involvement → @orner’s &yndrome
+ar2inson’s • dopamine depletion in nigrostriatal tracts
+eut)-egher’s &yndrome • melanin pigmentation of lips, mouth, hand, genitalia plus hamartomatous polyps of small intestine
+eyronie’s Disease • subcutaneous fibrosis of dorsum of penis
+ic2’s Disease • progressive dementia similar to Al)heimer’s
+lummer’s &yndrome • hyperthyroidism, nodular goiter, absence of eye signs (+lummer’s J rave’s - eye signs%
+lummer-!inson • esophageal ebs 6 iron-deficiency anemia, ↑ &00A of esophagus
+ompe’s Disease •
glycogen storage disease→
cardiomegaly+ott’s Disease • tuberculous osteomyelitis of the vertebrae
+otter’s 0omplex • renal agenesis → oligohydramnios → hypoplastic lungs, defects in extremities
*aynaud’s • Disease9 recurrent vasospasm in extremities• +henomenon9 $° to underlying disease (&
8/18/2019 USMLE Diseases
4/9
Wernic2e-7orsa2off &yndrome • thiamine deficiency in alcoholics4 bilateral mamillary bodies (confusion, ataxia, ophthalmoplegia%
Whipple’s Disease • malabsorption syndrome (ith bacteria-laden macrophages% 6 polyarthritis
Wilson’s Disease • hepatolenticular degeneration (copper accumulation 6 decrease in ceruloplasmin%
Wis2ott-Aldrich &yndrome • immunodeficiency9 combined "- 6?-cell deficiency (thrombocytopenia 6 ec)ema%
Wolff-0hai2off ffect • high iodine level (−%’s thyroid hormone synthesis
Men2er’s Diverticulum • esophageal4 cricopharyngeal muscles above 5&
Mollinger-llison • gastrin-secreting tumor of pancreas (or intestine% → acid → intractable ulcers
@allmar2 indingsAlbumino-0ytologic Dissociation • uillain-"arre (mar2edly increased protein in 0& ith only modest increase in cell count%
Antiplatelet Antibodies • idiopathic thrombocytopenic purpura
Arachnodactyly • 1arfan’s
Aschoff "odies • rheumatic fever
Auer *ods • acute promyelocytic leu2emia (A1< type 1/%
Autosplenectomy • sic2le cell anemia
"abins2i • 513 lesion
"asophilic &tippling of *"0s • lead poisoning
"ence ones +rotein • multiple myeloma free light chains (either 2appa or lambda%• Waldenstrom’s macroglobinemia
"irbec2 ranules • histiocytosis ; (eosinophilic granuloma%
"lue "loater • 0hronic "ronchitis
"oot-&haped @eart • ?etralogy of allot
"ouchard’s 3odes • osteoarthritis (+I+%
"outonniere’s Deformity • rheumatoid arthritis
"ron ?umor • hyperparathyroidism
"rushfield &pots • Don’s
0all-xner "odies • granulosa cell tumor
0ardiomegaly ith Apical Atrophy • 0hagas’ Disease
0hancre • #° &yphilis
0hancroid • @aemophilus ducreyi
0harcot ?riad • multiple sclerosis (nystagmus, intention tremor, scanning speech%
0harcot-
8/18/2019 USMLE Diseases
5/9
hon ocus : 0omplex • ?uberculosis (#° 6 $°, respectively%
oer’s 1aneuver • Duchenne’s 1D use of arms to stand
@eberden’s 3odes • steoarthritis (DI+%
@ein) "odies • L+D@ Deficiency
@emorrhagic 5rticaria • @enoch-&chonlein
@eterophil Antibodies • infectious mononucleosis ("!%
@irano "odies • Al)heimer’s
@ypersegmented +13s • 1egaloblastic anemia
@ypochromic 1icrocytic *"0s •
iron-deficiency anemiaarisch-@erxheimer *eaction • &yphilis over-aggressive treatment of an asymptomatic pt. that causes symptoms $° to rapid lysis
oint 1ice • osteoarthritis (fractured osteophytes%
7aussmaul "reathing • acidosis
7eratin +earls • &00A
7eyser-leischer *ing • Wilson’s
7immelstiel-Wilson 3odules • diabetic nephropathy
7oilocytes • @+!
7opli2 &pots • measles
8/18/2019 USMLE Diseases
6/9
*ouleaux ormation • multiple myeloma *"0’s stac2ed as po2er chips
&/ @eart &ound • &> @eart &ound • +ulmonary &tenosis• +ulmonary @?3
&chart)man *eaction • 3eisseria meningitidis impressive rash ith bugs
&imian 0rease • Don’s
&mith Antigen • &
8/18/2019 USMLE Diseases
7/9
0ardiac #° ?umor N 0hild • *habdomyoma
0ardiac ?umor N Adults • 1etasteses
0ardiomyopathy • Dilated (0ongestive% 0ardiomyopathy
0ause of $° @?3 • *enal Disease
0ause of Addison’s • Autoimmune ($nd N infection%
0ause of 0ongenital Adrenal @yperplasia • $#-@ydroxylase Deficiency (then, ##-%
0ause of 0ushings • xogenous &teroid ?herapy (then, #° ↑ A0?@, Adrenal Adenoma, ctopic A0?@%
0ause of death in Al)heimer pts • +neumonia
0ause of death in Diabetics •
1I0ause of Death in &
8/18/2019 USMLE Diseases
8/9
+rimary @yperparathyroidism • Adenomas (folloed by9 hyperplasia, then carcinoma%
+t. With @odg2in’s • Goung 1ale (except 3odular &clerosis type N emale%
+t. With 1inimal 0hange Disease • Goung 0hild
&econdary @yperparathyroidism • @ypocalcemia of 0hronic *enal ailure
&exually transmitted disease • 0hlamydia
&ite of Diverticula • &igmoid 0olon
&ite of metastasis • *egional
8/18/2019 USMLE Diseases
9/9
Induce 0+>KQ • "arbiturates• +henytoin• 0arbama)epine• *ifampin
Inhibit 0+>KQ • 0imetidine• 7etocona)ole
Interstitial 3ephritis • 1ethicillin• 3&AIDs (except Aspirin%• urosemide• &ulfonamides
1onday Disease • 3itroglycerin Industrial exposure → tolerance during ee2 → loss of tolerance during ee2end → headache,tach, di))iness upon re-exposure
range "ody luids • *ifampin
steoporosis • @eparin• 0orticosteroids
+ositive 0oombs’ ?est • 1ethyldopa
+ulmonary ibrosis • "leomycin• Amiodarone
*ed 1an &yndrome • !ancomycin
&evere @?3 ith ?yramine • 1AIs
&
Top Related