Tracking a protein through a cell
Organelles that Build Proteins
• Ribosomes, Endoplasmic Reticulum, Golgi Apparatus
• One of the most important jobs of the cell is making proteins
• Proteins are assembled on the ribosomes• Ribosomes are small particles of RNA and
proteins that produce other proteins using the coded instructions from DNA
• Ribosomes are assembled in the nucleolus
nucleusnucleolus
ribosomes
Endoplasmic Reticulum
Rough endoplasmic reticulum
Smooth endoplasmic reticulum
Proteins targeted for export to the cell membrane or to special locations such as lysosomes complete their assembly on ribosomes attached to the rough ER
Proteins targeted for export to the cell membrane or to special locations such as lysosomes complete their assembly on ribosomes attached to the rough ER
The smooth ER contains enzymes that synthesize membrane lipids and detoxification materials found in liver cells
Free ribosomes
Other cellular proteins are made on ribosomes which are not attached to ER
Golgi apparatus
Newly assembled proteins are carried from the rough ER to the golgi apparatus vesicles
The golgi apparatus modifies, sorts, and packages proteins and other materials for storage in the cell or transport out of the cell
It also ships proteins to their final destination
Ribosome
Large subunit
Small subunit
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