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Useful GeneticsProfessor Rosie Redfield

The University of British Columbia

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• Describe DNA replication• Explain the role of DNA replication

in the history of DNA

The history of DNA

a) DNA replication

b) The Cell Theory in biology

c) A ‘DNA Theory’ for genetic information

d) DNA’s evolutionary continuity

Lecture 1D

Outline:

Learning objectives:

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DNA replication

Image from Wikimedia Commons

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DNA replication

Image from Wikimedia Commons

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DNA replication

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Evolutionary continuity of life

Eukaryotes

Bacteria

Archaea

Most recent common ancestor of all life

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The Cell Theory in biology

Omnis cellula e cellula

"Every cell originates from another existing cell like it, by cell division.”

Virchow’s cell drawings from Wikimedia Commons

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Evolutionary continuity of life

Eukaryotes

Bacteria

Archaea

Most recent common ancestor of all life

cells

cells

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The DNA Theory

Omnis DNA e DNA

"Every DNA strand originates from a preexisting complementary DNA strand, by DNA replication.”

DNA sketch from Wikimedia Commons

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Evolutionary continuity of life

Eukaryotes

Bacteria

Archaea

Most recent common ancestor of all life

DNA

DNA

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What we’ve done

a) DNA replication• Each strand is the template for

a new strand• Each new dsDNA has one old

strand and one new strand

b) DNA’s evolutionary continuity• like cells, all DNA is copied

from existing DNA

• All DNAs are descended in a lineage from the first DNA.

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Coming up....

What makes a DNA sequence a gene?

Lecture 1E

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