The European Commission’s science and knowledge service Joint Research Centre
INDOOR AIR TOXICOLOGY Conference 16-18 September 2018, Berlin, Germany
The European Commission’s Information Platform for Chemical Monitoring data (IPCHEM): a reference gateway for searching, accessing, retrieving, assessing and sharing indoor air monitoring data in EU
Stylianos Kephalopoulos (European Commission, DG JRC)
2
IPCHEM - policy background
ASSESSING EU REGULATIONS Effectiveness/efficiency of the EU regulatory
framework implementation
Revision/integration of the current EU Regulatory framework
SOLVING DATA AND INFORMATION NEEDS Solving the problem of data and information scattered across a multitude of disconnected systems, repositories and databases
RESPONDING TO POLICY NEEDS EC Communication “The combination effects of chemicals
Chemical mixtures”
7th EU Environment Action Programme (2014-2020)
SOLVE
ASSESS
RESPOND
IPCHEM – Policy Background
European Commission Communication on “The combination effects of chemicals – Chemical mixtures” (COM/2012/0252 final) recognises the need of: “Promoting a more coherent approach to the generation,
collection, storage and use of chemical monitoring data in relation to humans and the environment, through the creation of a platform for chemical monitoring data”.
7th Environment Action Programme (2014-2020) priority objective 5: “To improve the knowledge and evidence base for Union Environmental Policy”
European Commission’s requirement to: Assess the effectiveness and efficiency of the EU regulatory framework implementation; including EU Environmental Monitoring and Reporting
IPCHEM – Policy Background
5
IPCHEM – salient elements
One access point, all the information
A strong strategic partnership
A wealth of chemical monitoring data
Expanding recognition and impact
https://ipchem.jrc.ec.europa.eu
IPCHEM – Salient elements
A fast track system to make chemical monitoring data readily accessible and comparable across various media (e.g. environment, humans, food/feed, indoor air and consumer products) and policy domains
Enables an informed policy-making process on the basis of timely delivered and quality data
One access point, all the information
A strong strategic partnership
A wealth of chemical monitoring data
Expanding recognition and impact
One access point, all the information
A strong strategic partnership
A wealth of chemical monitoring data
Expanding recognition and impact
146.829.052 CONCENTRATION MEASUREMENTS
2040 SUBSTANCES AND COMPOUNDS
34 DATA COLLECTIONS
14 HBM4EU METADATA
+ AROUND 60 NEW HBM4EU METADATA AND DATA IN AUTUMN/WINTER 2018
One access point, all the information
A strong strategic partnership
A wealth of chemical monitoring data
Expanding recognition and impact
EC REPORT ON THE SUSTAINABLE USE OF BIOCIDES
March 2016
EC STAFF WORKING DOCUMENT IMPACT ASSESSMENT DEFINING CRITERIA FOR IDENTIFYING ENDOCRINE
DISRUPTORS June 2016
SUBMISSION BY THE EU AND ITS MEMBER STATES IN RESPONSE TO THE REQUESTS TO PREPARE A GLOBAL LEGALLY BINDING INSTRUMENT ON
MERCURY October 2016
EUROPEAN COMMISSION AMR ACTION PLAN A EUROPEAN ONE HEALTH ACTION PLAN AGAINST ANTIMICROBIAL RESISTANCE
(AMR) June 2017
CONCLUSIONS OF THE COUNCIL OF THE EUROPEAN UNION ON THE PROTECTION OF HUMAN HEALTH AND THE ENVIRONMENT THROUGH THE SOUND
MANAGEMENT OF CHEMICALS December 2016
EC STAFF WORKING DOCUMENT TOWARDS A FITNESS CHECK OF EU ENVIRONMENTAL MONITORING AND REPORTING
May 2016
IPCHEM ONE OF THE CASE STUDIES Identified as best fitting into the EC-JRC DATA4POLICY INITIATIVE
May 2017
One access point, all the information
A strong strategic partnership
A wealth of chemical monitoring data
Expanding recognition and impact
IPCHEM – Level of data granularity and access groups
Based on: the IPCHEM Data Policy, the Reg. 45/2001 and GDPR
Data retrievable through IPCHEM: shall be made available to all users at highest possible level of data granularity and under the conditions of free, full, open and timely access
Metadata: mandatory by default
Aggregated data: mandatory for European Commission and EU Agencies
Dedicated regimes and rules for Research Projects: for the project duration
Occurrence data (not exposure), i.e. chemical concentrations values measured in various media across Europe and beyond by EC services, EU Agencies, National Bodies, Research centres and consortia, e.g.:
• data collected for legal obligations on ad-hoc or regular basis for reporting monitoring data at European or national levels
• data generated as result of targeted research on the presence of known or unknown chemical substances in specific media
Type of data currently accessible through IPCHEM
Data collections in IPCHEM are grouped under four thematic modules:
Human Biomonitoring data
Environmental monitoring data
Food and Feed monitoring data
Product and indoor air monitoring data
146.829.052 (24.000.000)2017
MEASUREMENT RECORDS (excluding data under integration)
2.040 (1600)2017
NUMBER OF CONTROLLED SUBSTANCES (i.e. quality controlled and not duplicated)
Type of chemical data in IPCHEM module and media Human Biomonitoring data* (20)
Environmental data* (19)
Product and Indoor Air data (3)
20
19
3 3
HBM ENV INDOOR FOOD
DATA/METADATA INTEGRATED IN IPCHEM
MID. 2018
* The Environmental Specimen Bank of Germany stores both HBM and ENV data
Blood-whole blood Blood -plasma Blood -serum Cord blood: whole blood/plasma/serum Urine: spot/24h/morning urine Saliva/sputum Semen Hair Breast milk Adipose Tissue/Fat
Surface water Ground water Industrial water Drinking water Atmospheric water Suspended particulate matter (SPM) Sediment in water Biowaste Sewage sludge Refuse derived fuels (RDF) Demolition waste Ashes Other city waste Topsoil Subsoil Underwater/subaqueous soil Plants Animals Bacteria
Outdoor air
Indoor air
Personal Sampling
Under refinement
Food and Feed data (3)
Spatial coverage and resolution 0,
4083
61
0,53
3102
0,02
2
0,03
3978
0,05
375
0,80
5368
0,24
2615
0,02
9009
0,25
9096
17,4
4397
4
2,49
7328
0,05
2052
0,12
0412
0,18
6369
3,08
306
0,02
8615
0,06
2246
0,02
2303
0,01
1042
2,19
5094
0,19
8299
0,19
081
0,08
0868
0,25
3218
0,09
2046
0,76
5873
0,26
7517
2,75
5498
0
5
10
15
20
Mill
ione
n
Measurements records per Country (EU28), end of 2017
0 0 2
10 5 3
6 7 3
15
5 4
05
101520
Level of coverage of IPCHEM data, mid 2018
IPCHEM Data
IPCHEM-HBM data
Level of detail and accessibility in IPCHEM
6
11
2 0
5
0 1
13
1 0 2
0 0 0 3
0 02468
101214
Aggregated Singlemeasurement
Singlemeasurements
filtered orgeneralised
Metadata only(temporal)
IPCHEM-Level of Data granularity-end 2017
Environment Human Biomonitoring Products&Indoor Air Food&Feed
8 8
3 5
1 2 2 1 1 3
0 0 0
5
10
Public Restricted to EC and EUAgencies
Under integration
IPCHEM-Level of Data accessibility-mid 2018
Environment Human Biomonitoring Products&Indoor Air Food&Feed
IPCHEM – Main tools and functionalities
Interoperability With relevant international Information Systems/web services for establishing a more comprehensive knowledge framework on chemical exposure
Data comparability Spatial and temporal comparative analysis across chemicals/media
Data quality To properly understand, use/re-use the data that are accessible and retrievable through IPCHEM
IPCHEM - as Improver
IPCHEM OBJECTIVES
Search page
Metadata info page
Database Console
Basket tool
Map viewer
IPCHEM: Main Tools & Funtionalities
Links with relevant information systems and services
Definition and implementation of Central IPCHEM Quality Control Rules Rules are ingested into the IPCHEM ETL process service and launched IPCHEM ETL creates the “IPCHEM Quality and Harmonisation Report” shared with the data providers Any remaining quality issues are flagged and displayed into the IPCHEM DB console
IPCHEM: Salient Features DATA QUALITY IPCHEM Data Quality Control Rules
IPCHEM: Salient Features DATA COMPARABILITY
IPCHEM internal Data Model
“Chemical Monitoring data” definition and data templates
Definition of the IPCHEM internal data model
Internal IPCHEM ETL mechanism for data mapping, transformation and integration
IPCHEM Data Visualisation options
Direct link for each chemical searchable via IPCHEM from the “structural information and properties” window
Built on CAS registry number (exceptionally on chemical name)
IPCHEM: Salient Features INTEROPERABILITY
Linking external Information Systems by chemical ID
Solved case by case, via: • Web services with
third party repository (ChemAgora)
• Provision of links (eChemPortal), on regular basis
• Scheduled download and update of links (ECHA info card)
IPCHEM: Salient Features INTEROPERABILITY
Linking database’s web application by record ID
Use of the ID sampling record to link IPCHEM with an external database web application (e.g. the ESB of UBA) to trace each record from IPCHEM to the source database and vice-versa
The web application of the
external database might provide additional information (e.g. further attributes not provided to IPCHEM)
IPCHEM: new Tools & Functionalities
IPCHEM Advanced Search Tool
Module-based filter criteria (the first one is for HBM data)
Extended to search multiple chemicals, groups and relations (e.g. parent compounds and their metabolites, HBM4EU group of priority substances)
Quality control and chemical names, synonyms, IDs, groups and relations are managed into the IPCHEM Chemical Nomenclature Registry
The new IPCHEM version will be released by end of October 2018
IPCHEM: new Tools & Functionalities
IPCHEM Advanced Viewer
Search/view/download multiple chemicals by location: typing a city or drawing an area
The new IPCHEM version will be released by end of October 2018
IPCHEM – Module 4 ‘Products & Indoor Air Data’
AIRMEX - European Indoor Air Monitoring and Exposure Assessment Project • 27 chemicals • 9 EU Countries • 8.487 SINGLE concentration measurements OFFICAIR - Indoor air pollution in modern office buildings • 33 chemicals • 7 EU Countries • 11.156 SINGLE concentration measurements SINPHONIE - Schools Indoor Pollution and Health Observatory Network in Europe database on chemical and biological pollutants • 11 chemicals • 22 EU Countries • 2165 SINGLE concentration measurements
• Links to BUMA and BUMAC, providing product emissions and health relevant thresholds
IPCHEM Module 4 ‘Products & Indoor Air Monitoring Data’
IPCHEM Module 4 ‘Products & Indoor Air Monitoring Data’
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European Energy Efficiency Platform E3P
Workshop on IPCHEM-Module 4 ‘Indoor Air Monitoring Data’ (2-3 October 2017, Ispra)
• Enhancing and expanding the scope of the IPCHEM-Module 4 metadata and data model so that existing and future data collections on Indoor Environment Data can serve policies cross cutting the chemical policy (e.g. on health and energy performing buildings).
• Integrating IPCHEM-M4 data into the DG ENER’s EU Building Stock Observatory & JRC’s European Energy Efficiency Platform – E3P
• The further enhancement will rely on and benefit from on-going and former relevant harmonisation efforts undertaken by European Commission and other international organisations;
• Engage potential data providers
IPCHEM Module 4: improving data and metadata model and increasing indoor air monitoring data collections
29
n Data Collection Providers Level of detail Accessibility Media Spatial Coverage Temporal coverage
1 National monitoring programs on IAQ in Belgium
VITO, BBIEM
Aggregated data
Public Indoor air Belgium -
2 The OQAI French Indoor Air Quality Observatory
French Authorities
Aggregated data later single measurements, filtered or generalised data
Public Indoor air France From 2001
3 IAQ data of the German Environmental Survey (GerES)
UBA-Germany
Aggregated data Public Indoor air Germany Several years, to be decided
4 Indoor air quality study - CO2 concentration in preschools/schools in Estonia
Health Board-Estonia
Single measurements, filtered or generalised data
Public Indoor air Estonia 2007-2008
Indoor Air Monitoring Data Integration Plan 2018-2019 (1/3)
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n Data Collection Providers Level of detail Accessibility Media Spatial Coverage Temporal coverage
5 GENASIS Database RECETOX, Masaryk University
Aggregated data
Single measurements, filtered or generalised data
Public Indoor air World 2005-2016
6 Survey of indoor air quality in insulated and not insulated school buildings in Tallinn
Health Board-Estonia
Single measurements, filtered or generalised data
Public Indoor air in insulated and not insulated schools
Estonia 2015
7 Emerging contaminants dataset, EMERTOX, Toxicology dataset
RECETOX, Masaryk University
Aggregated data
Single measurements, filtered or generalised data
Public Indoor air
Outdoor air
World 2005-2008
Indoor Air Monitoring Data Integration Plan 2018-2019 (2/3)
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n Data Collection Providers Level of detail Accessibility Media Spatial Coverage Temporal coverage
8 INSULAtE project National Institute for Health and Welfare, Finland
Single measurements, filtered or generalised data
Public Indoor air Finland 2011-2015
9 Indoor environmental data (pollutants and comfort) in Greece from various types of spaces – Personal Exposure
National and Kapodistrian University of Athens
Single measurements data
Public Indoor air Greece 2012-2017
10 IAQ in Lithuanian low energy buildings
Kaunas University of Technology, Lithuania
Single measurements, filtered or generalised data
Restricted to EC and EU Agencies;
Restricted to EU MS
Indoor air Lithuania 2014
Indoor Air Monitoring Data Integration Plan 2018-2019 (3/3)
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IPCHEM - salient collaborations
33
IPCHEM – HBM MODULE EXTENSION
IPCHEM is the official platform (long-term HBM data repository) for accessing and sharing existing and new human biomonitoring data collected during the HBM4EU project (2017-2022).
Agreement for integrating OECD HBM db into IPCHEM (OECD Working Party Exposure Assessment - June 2017)
The European Human Biomonitoring Initiative (HBM4EU) is a joint effort of 26 countries and the European Commission which aims to coordinate and advance human biomonitoring in Europe.
Using IPCHEM as the platform for searching, retreiving, accessing HBM metadata and data on global scale
34
84 HBM4EU metadata was compiled in 2018 by HBM4EU partners sharing data and metadata via IPCHEM and stored into the IPCHEM-HBM4EU Data Repository (IPCHEM share).
Once quality checked by IPCHEM team, the metadata is published in IPCHEM and approved by
the data providers
Once approved the metadata page is indexed and available on line from the IPCHEM search tool
So far 14 metadata are published in IPCHEM, the remaining 70 will be published by the HBM
Conference “Human Biomonitoring in Europe –science and policy for healthy citizens”, September 28, 2018 in Vienna (Austrian Presidency of the Council of the European Union)
2 HBM4EU data collections has been integrated into IPCHEM (both of Israel), still under final
quality control by IPCHEM team
HBM4EU data collections/metadata integrated into IPCHEM (mid 2018)
IPCHEM – HBM MODULE EXTENSION
35
IPCHEM – EFSA DATAWAREHOUSE data sharing
Centralised data
(S-DWH) Implemented
data flows Matrix
(data from applications)
Self-service data
(Zenodo)
Data sharing supported by
EFSA
External data
sources Access/retrieve data from EFSA Data Lake
IPCHEM
Access/retrieve IPCHEM data & metadata
36
IPCHEM as potential platform to track chemical of concern in products/articles within the EU Circular Economy context
Chemicals in
Products
Prioritisation
Assessment
Criteria
Tracking
How can IPCHEM support the tracking, prioritisation and assessment of chemicals of concern in products/articles (e.g. toys, electronics, textiles, construction materials/products), the environment, the food-web, indoor environments and humans?
According to the EU Circular Economy Action Plan (from production, consumption, waste and recycling)
SAICM - Chemicals in Products Program (CiP) Synergistically with relevant developments on global scale (e.g. UNEP-
SETAC, USEtox, Tox21, ConsExpo, OECD WPEA, ECHA REACH, SubsPort, etc.)
Kick-off discussions, Workshop IPCHEM-M4 ‘PRODUCTS DATA’, 26-27 October 2017, Ispra
Experts from DGs ENV, JRC, ECHA, EEA, US EPA, HEALTH CANADA, OECD and experts from EU MS
37
IPCHEM supporting the assessment of chemical mixtures
Workshop ‘IPCHEM Supporting the assessment of chemical mixtures, 11-12 December 2017, JRC-Ispra
Purpose: • How can IPCHEM be used for mixture risk assessment (MRA)?
• What data collections, data elements and templates should IPCHEM integrate to support MRA practices
• What functionalities IPCHEM is currently featuring and which should be developed additionally in the future to support exposure and risk assessment of mixtures?
• Which other tools, e.g. databases and information systems developed in H2020 funded projects on chemical mixtures should become interoperable with IPCHEM?
Joint H2020 Workshop (29-30 May 2018, JRC-Ispra)
Purpose: to create a joint forum for researchers and policy-makers to discuss and identify gaps in risk assessment and governance of chemical mixtures. It has addressed how the state-of-the-art knowledge can be used to prioritise new initiatives and strategies to limit unwanted impact on human health and the environment from combined exposure to multiple chemicals.
38
IPCHEM – our partners’ view
• Established in the 1980s
• Annual collection of aquatic, terrestrial, and human samples which reflect a broad cross-section of environmental conditions in Germany.
• Samples are cryo-preserved for retrospective analyses
• Annual quantification of a fixed set of pollutants
1) The German Environmental Specimen Bank (ESB) German Environment Agency (UBA): IPCheM Experiences
39 August 29th 2018 | ISES-ISEE (Ottawa, Canada)
2) The German POP-Dioxin Database German Environment Agency (UBA): IPCheM Experiences
40 August 29th 2018 | ISES-ISEE (Ottawa, Canada)
• Since 1991: compile, document, and evaluate data from monitoring programs at Government and Federal State level
• Data on dioxins and other POPs managed in a harmonized way including specific metadata (reason of investigation, location, sampling, analysis, and administrative aspects)
• Analytical data is stored as congeners. Calculation of toxicity equivalents (TEQ) can be updated or compared between different approaches.
3) Database on Pharmaceuticals in the Environment German Environment Agency (UBA): IPCheM Experiences
41 August 29th 2018 | ISES-ISEE (Ottawa, Canada)
Sour
ce: d
jaha
n / F
otol
ia.c
om
• Result of comprehensive literature review (1981-2013): 1,016 original publications and 150 reviews
• Data on observed environmental concentrations of human and veterinary pharmaceuticals worldwide
• Systematic database on substances in surface water, groundwater, drinking water, manure, soil, and other environmental matrices
Conclusions and Outlook German Environment Agency (UBA): IPCheM Experiences
42 August 29th 2018 | ISES-ISEE (Ottawa, Canada)
• IPCHEM participation helps in fully tapping the value of data for science and policy-making by putting them into a broader context and making them widely accessible.
• Timely access for policy makers and regulatory agencies to sound monitoring data
• Increasing international visibility of own activities is a key benefit.
DB on Pharmaceuticals in the Environment updated in 2018 (approx. 20.000 new entries)
Future contributions to IPCHEM are i. a. indoor air monitoring data of the German
Environmental Survey (GerES) and from HBM4EU.
IPCHEM: The reference platform for chemical monitoring data in Europe
A unique and reference access point for searching, accessing, retreiving chemical occurence data in different media EU and beyond
Developed as distributed infrastructure Strategy, user requirements, Data Policy and governance defined in collaboration with IPCHEM partners Providing hosting facilities for orphan data and research data Improving quality, comparability, standardisation of chemical data and metadata Handling heterogeneity of data sources, formats and accessibility regimes Promoting and, where possible, implementing, the overarching principles of free, full, open and timely access to
chemical monitoring data and interoperability with other existing relevant information systems and web services Facilitating assessments Streamlining data reporting
https://ipchem.jrc.ec.europa.eu/
IPCHEM – Driving Data & Knowledge Sharing
Enables Risk assessment of combination effects; Early warning system; Alert system between environment and food; Correlation of assessments
Improves Risk assessment; Prioritisation of chemicals; Validation of exposure and
deposition models; Policy effectiveness evaluation; State of environment evaluation
Saves Resources for data collections and data
storing; Burden for reporting;
The benefits of using IPCHEM
IPCHEM – Driving Data & Knowledge Sharing
Scientific coordinator:
• Stelios Kephalopoulos (F.7)
Technical coordinator:
• Silvia Dalla Costa (B.6)
Developing and support team:
• Alberto Cusinato (B.6)
• Roberto Sgnaolin (B.6)
• Vittorio Reina (F.2)
• Dorelia Lipsa (F.2)
• Otmar Geiss (F.2)
• Mariana Valerio (F.2)
The JRC’s IPCHEM Team Supervisors:
• Guy Van Den Eede (HoU F.7)
• Arnd Hoeveler (HoU F.2)
• Maurice Whelan (HoU F.3)
• Alessandro Annoni (HoU B.6)
Other contributing JRC Units:
• Nick Nicholson (F.1)
• Clemens Wittwehr (F.3)
• Stephanie Bopp (F.3)
• A. Pistocchi (D.2)
Please contact us:
46
Stay in touch
•EU Science Hub: ec.europa.eu/jrc
•Twitter: @EU_ScienceHub
•Facebook: EU Science Hub - Joint Research Centre
•LinkedIn: Joint Research Centre
•YouTube: EU Science Hub
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