SECTION 1 INTRODUCTIONCHAPTER1Introduction to Concepts of Pathology 1CATHERINEC. GOODMAN
Pathogenesis of Disease, 1Concepts of Health, IIIness, and Disability, 1Theories of Health and IIIness, 7Health Promotion and Disease Prevention, 9Genetic Aspects of Disease, 11
CHAPTER2Behavioral, Social, and Environmental FactorsContributing to Disease and Dysfunction 17SUSANA. SCHERER.IRAGORMAN .CATHERINEC.GOODMAN
Overview, 17Clinical Models of Health, 18Variations in Client Populations, 19Lifestyle Factors That Intluence Health, 26Behavioral Intluences on Health, 44Environmental Barriers to Health Care, 52
CHAPTER3The Psychosocial-Spirituallmpact on HealthCare 54BONNIE YOST .CATHERINEC. GOODMAN
Psychologic Considerations in Health Care, 54Terminology, 57Effects of Trauma on Brain Development, 58Brain Function: A Review of Organization and Healing
Potential, 63Spiritual Development in the Health Care Profession, 71Special Role of the Physical Therapist, 73Specific Psychologic Conditions, 74Chronic Pain Disorders, 105Mood Disorders, 109Suicide, 118
CHAPTER4Environmental and OccupationalMedicine 121CATHERINEc. GOODMAN
Introduction, 121Environmental Medicine, 122Occupational Injuries and Diseases, 138
CHAPTER5Problems AHecting Multiple Systems 150CELESTEPETERSON .CATHERINEC. GOODMAN
Systemic Effects of Pathology, 150Adverse Drug Reactions, 152Specific Drug Categories, 156Radiation Injuries, 166Chemotherapy, 173
Specific Disorders Affecting Multiple Systems, 179Fluid and Electrolyte Imbalances, 182Acid-Base Imbalances, 192
CHAPTER6Iniury, Inflammation, and Healing 197CATHERINEc. GOODMAN
STEVENH. TEPPER.D. MICHAELMCKEOUGH(FIRSTAND SECONDEDITIONS)
Cellular Aging, 197Cell Injury, 198Tissue Healing, 208Phases of Healing, 215Specific Tissue or Organ Repair, 230
SECTION 2 CLlNICALMEDICINECHAPTER7The Immune System 241ZOHER F. KAPASI .CATHERINEC. GOODMAN
Typesof Immunity, 241The Immune Response, 242Aging and the Immune System, 250Factors Affecting Immunity, 251Interactions Between the Immune and Central Nervous
Systems, 252Exercise Immunology, 253Immunodeficiency Diseases, 255Hypersensitivity Disorders, 277Autoimmune Diseases, 280Isoimmune Disease, 296
CHAPTER8Infectious Disease 298CATHERINEc. GOODMAN .CELESTEPETERSON
Signs and Symptoms of Infectious Diseases, 299Aging and Infectious Diseases, 301Infectious Diseases, 301Specific Infectious Diseases, 315Viral Infections, 326Miscellaneous Infectious Diseases, 339
CHAPTER9Oncology 348CATHERINEc. GOODMAN
Definitions, 348Classifications of Neoplasm, 349Incidence, 351Etiology, 352Risk Factors, 353Pathogenesis, 357Invasion and Metastases, 359Clinical Manifestations, 363Medical Management of Cancer, 368Cancer, Physical Activity, and Exercise Training, 385Childhood Cancer, 390
xvii
CHAPTER10
The Integumentary System 392HARRlffi B. LOEHNE . CATHERINE C. GOODMAN
Skin Lesions, 392Signs and Symptoms of Skin Disease, 392Aging and the Integumentary System, 396Common Skin Disorders, 398Skin Infections, 402Skin Cancer, 410Skin Disorders Associated With Immune
Dysfunction, 421Thermal Injuries, 433Miscellaneous Integumentary Disorders, 442
CHAPTER11
The Endocrine and Metabolic Systems 453CATHERINE c. GOODMAN
Endocrine System, 453Specific Endocrine Disorders, 461Metabolic System, 515Specific Metabolic Disorders, 517
CHAPTER12
The Cardiovascular System 519CATHERINE c. GOODMAN · IRINA V. SMIRNOVA
Signs and Symptoms of Cardiovascular Disease, 519Aging and the Cardiovascular System, 524Gender Differences and the Cardiovascular
System, 525Diseases Affecting the Hean Muscle, 528Disease Affecting the Cardiac Nervous System, 588Diseases Affecting the Hean Valves, 594Diseases Affecting the Pericardium, 605Diseases Affecting the Blood Vessels, 607Other Cardiac Considerations, 637
CHAPTER13The Lymphatic System 642BONNIE B. LASINSKI
Anatomy and Physiology, 642Inflammation and Infection in the Lymphatic
System, 647
CHAPTER14
The Hematologic System 678CELESTE PETERSON . CATHERINE C. GOODMAN
Signs and Symptoms of Hematologic Disorders, 678Aging and the Hematopoietic System, 681BIood Transfusions, 681Disorders of Iron Absorption, 684Disorders of Erythrocytes, 685Disorders of Leukocytes, 690Neoplastic Diseases of the BIood and Lymph
Systems, 693Disorders of Hemostasis, 716
CHAPTER15The Respiratory System 742BETHIKEDA · CATHERINEC.GOODMAN
Overview, 742Aging and the Pulmonary System, 746Infectious and Inflammatory Diseases, 749Obstructive Diseases, 759Environmental and Occupational Diseases, 783Near Drowning, 787
Congenital Disorders, 788Parenchymal Disorders, 799Disorders of the Pulmonary Vasculature, 816Disorders of the Pleural Space, 822
CHAPTER16The Gastrointestinal System 828CATHERINEc. GOODMAN
Signs and Symptoms of Gastrointestinal Disease, 828Aging and the Gastrointestinal System, 832The Esophagus, 833The Stomach, 841The Intestines, 848The Appendix, 875The Peritoneum, 878The Rectum, 879
CHAPTER17The Hepatic, Pancreatic, and BiliarySystems 881CATHERINEc. GOODMAN .CElESTE PETERSON
Signs and Symptoms of Hepatic Disease, 881Aging and the Hepatic System, 883Healing in the Hepatic System, 883Liver, 884Pan creas, 912Biliary, 918
CHAPTER18The Renal and Urologic Systems 927CATHERINEc. GOODMAN .CELESTEPETERSON
Aging and the Renal and Urologic Systems, 927Infections, 928Renal Disorders, 932Disorders of the BIadder and Urethra, 950
CHAPTER19
The Male Genital/Reproductive System 964CATHERINEc. GOODMAN
Aging and the Male Reproductive System, 964Disorders of the Prostate, 964Disorders of the Testes, 978
CHAPTER20The Female Genital/ReproductiveSystem 986CATHERINEc. GOODMAN
Aging and the Female ReproductiveSystem, 986Exercise and the Reproductive System, 994Sexual Dysfunction, 994Disorders of the Uterus and Fallopian Tubes, 995Disorders of the Ovaries, 1005Pelvic Floor Disorders, 1010Breast Disease, 1015
CHAPTER21Transplantation 1037CHRISl. WElLS.CATHERINEC.GOODMAN
Incidence, 1037Types ofTransplantation, 1037Organ Procurement and Allocation, 1039Advances and Research in Transplantation, 1045Biopsychosocial Implications, 1048Posttransplant Complications, 1051
Organ Transplantation and Exercise, Activity, andSpons, 1056
Hematopoietic Cell Transplantation, 1059Organ Transplantation, 1066
SECTION3 PATHOLOGYOFTHEMUSCULOSKELETALSYSTEM
CHAPTER22
Introduction to Pathology of theMuseuloskeletal System 1099CATHERINEc. GOODMAN
Advances in Musculoskeletal Biotechnology, 1100Biologic Response to Trauma, 1100Aging and the Musculoskeletal System, 1101The Musculoskeletal System and Exercise, 1104Musculoskeletal System Disease, 1106
CHAPTER23
Genetie and Developmental Disorders 1108ALlAN GLANZMAN
Down Syndrome, 1108Scoliosis, 1111Kyphoscoliosis, 1116Spina Bifida Occulta, Meningocele,
Myelomeningocele, 1116Developmental Dysplasia of the Hip, 1126Neuromuscular Disorders, 1130Torticollis, 1145Erb's Palsy, 1147Osteogenesis Imperfecta, 1150Arthrogryposis Multiplex Congenita, 1154
CHAPTER24Metabolie Disorders 1157CATHERINEc. GOODMAN
Osteoporosis, 1157Osteomalacia, 1173Paget's Disease, 1176
CHAPTER25Infectious Diseases of the MuseuloskeletalSystem 1182CATHERINE c. GOODMAN
Osteomyelitis, 1182Infections of Prostheses and Implants, 1187Diskitis, 1191Infectious (Septic) Arthritis, 1192Infectious (Inflammatory) Muscle Disease, 1195Extrapulmonary Tuberculosis, 1197Summary of Special Implications for the Therapist, 1200
CHAPTER26
Museuloskeletal Neoplasms 1201CATHERINEc. GOODMAN
Primary Tumors, 1201Primary Benign Bone Tumors, 1209Primary Malignant Bone Tumors, 1212Multiple Myeloma, 1222Primary Soft Tissue Tumors, 1223Metastatic Tumors, 1229
CONTENTS
CHAPTER27Soft Tissue, Joint, and Bone Disorders 1235CATHERINEc. GOODMAN
Soft Tissue, 1235Joint, 1250Bone, 1294
SECTION4 PATHOLOGYOFTHENERVOUSSYSTEM
CHAPTER28Introduction to Central Nervous SystemDisorders 1319KENDAS. FULLER
Overview, 1319Pathogenesis, 1319Clinical Manifestations, 1326Diagnosis, 1344Treatment, 1346Prognosis, 1348
CHAPTER29Infectious Disorders of the Central NervousSystem 1352KENDAS. FULLER
Overview, 1352Meningitis, 1352Encephalitis, 1356Brain Abscess, 1361Prion Disease, 1362
CHAPTER30
Central Nervous System Neoplasms 1365SHARONM. KONECNE
Introduction, 1365Primary Brain Tumors, 1367Specific Primary Brain Tumors, 1369Primary Intraspinal Tumors, 1393Metastatic Tumors, 1396Paraneoplastic Syndromes, 1399Leptomeningeal Carcinomatosis, 1400Pediatric Tumors, 1400
CHAPTER31Degenerative Diseases of the Central NervousSystem 1402KENDAS. FULLER.PATRIClA A. WINKLER
JOHN R.CORBOY(SECONDEDITION)
Amyotrophic Lateral Sclerosis, 1402Alzheimer's Disease, Alzheimer's Dementia, and
Variants, 1411Dystonia, 1419Huntington's Disease, 1422Multiple Sclerosis, 1425Parkinsonism and Parkinson's Disease, 1437
CHAPTER32Stroke 1449KENDAS. FULLER
Stroke, 1449Vascular Disorders of the Spinal Cord, 1471
CONTENTS
CHAPTER33Traumatic Brain Iniury 1477KENDAS. FUlLER
Traumatic Brain Injury, 1477Traumatic Brain Injury in Children, 1493
CHAPTER34Traumatic Spinal Cord Iniury 1496KENDA S. FULLER
Spinal Cord Injury, 1496
CHAPTER35Cerebral Palsy 1517AlLAN GLANZMAN
Cerebral Palsy, 1517
CHAPTER36Epilepsy 1532KENDA S. FUllER
Epilepsy, 1532
CHAPTER37Headache 1547KENDA S. FUllER
Overview, 1547Primary Headaches, 1548Secondary Headaches, 1561
CHAPTER38Vestibular Disorders 1566KENDAS. FUlLER
Vestibular Disorders, 1566
CHAPTER39The Peripheral Nervous System 1595MARCIA B. SMITH
Structure, 1595Peripheral Nervous System Changes With Aging, 1595Response to Injury, 1597Classification of Nerve Injury, 1597Classification of Neuropathy, 1599Signs and Symptoms of Peripheral Dysfunction, 1599Pathogenesis and Diagnosis of Peripheral
Dysfunction, 1601
Hereditary Neuropathies, 1601Mechanical Injuries: Compression and Entrapment
Syndromes, 1604Metabolic Neuropathies, 1617InfectionsjInflammations, 1621Cancer-Induced, 1628Toxins, 1629Motor Endplate Disorders, 1631Botulism, 1633Abnormal Response in Peripheral Nerves, 1634
CHAPTER40Laboratory Testsand Values 1637GlENN lo IRION · CATHERINEC. GOODMAN
Laboratory Tests, 1637Basic Metabolic Panel, 1639Comprehensive Metabolic Panel, 1644Complete Blood Count, 1646Blood Tests, 1648Erythrocyte Sedimentation Rate, 1651Hemostasis, 1652Cardiovascular Lab Tests, 1654Serum Hormones, 1660Immunologic, 1661Urinalysis, 1662Drug Screening, 1663Microbiologic Studies, 1663Pulmonary Function Tests, 1664Fluid Analysis, 1666
Appendix A: Summary of StandardPrecautions 1669
Historical Perspective, 1669Universal Precautions, 1669Standard Precautions, 1670Sources of Potential Exposure for the Therapist, 1671
Appendix B: Guidelines for Activity andExercise 1674
Medications and Exercise, 1674Guidelines for Monitoring Vital Signs, 1674Guidelines for Aquatic Physical Therapy, 1681
Index 1685
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