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CardiovascularDynamics
Schematicof
CirculatorySystem
systemiccircuit
pulmonarycircuit
heart
left atriumleft ventricle
aortapulmonaryarterypulmonaryveins
The Heart
inferiorvena cava
The Heartsuperior
vena cava
right ventricleright atrium
pulmonaryartery
pulmonary veins
bicuspidvalve
aorticsemilunarvalve
tricuspidvalve
pulmonarysemilunar
valve
Heart Valves
BloodFlow
Throughthe
Heart
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ContractionCycle of the
Heart
ContractionCycle of the
Heart
ContractionCycle of the
Heart
BloodVessel
Structure
simplesquamousepithelium
smoothmuscletissue
connectivetissue
Arteries• Carry blood away from the heart.
• Thick-walled to withstandhydrostatic pressure of theblood during ventricular systole.
• Blood pressure pushes bloodthrough arteries.
Veins• Carry blood to the heart.• Thinner-walled than arteries.• Possess one-way valves
that prevent backwardsflow of blood.• Blood flow due to body
movements, not fromblood pressure.
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One-WayValves in
Veins
Schematicof
CirculatorySystem
systemiccircuit
pulmonarycircuit
heart
Schematicof
CirculatorySystem
systemicarteries
pulmonaryarteries
capillarybeds
capillarybeds
systemicveins
pulmonaryveins
Blood Pressure
Mechanics of CirculationSome Definitions
Blood FlowBlood Pressure
Peripheral ResistanceBlood Viscosity
Factor InfluencingPeripheral Resistance
Blood ViscosityVessel RadiusVessel Length
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Poiseuille’s Equation
Blood Flow (∆Q) = πΔPr 4
8ηl
Poiseuille’s Equation
π = pi ( ≈ 3.14)
Blood Flow (∆Q) = πΔPr 4
8ηl
Poiseuille’s Equation
ΔP = pressure difference
Blood Flow (∆Q) = πΔPr 4
8ηl
Poiseuille’s Equation
r = vessel radius
Blood Flow (∆Q) = πΔPr 4
8ηl
Poiseuille’s Equation
η = blood viscosity
Blood Flow (∆Q) = πΔPr 4
8ηl
Poiseuille’s Equation
l = vessel length
Blood Flow (∆Q) = πΔPr 4
8ηl
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VesselResistance
Pump MechanicsSome Definitions
End Diastolic Volume (EDV)End Systolic Volume (ESV)
Cardiac OutputStroke Volume (SV = EDV - ESV)
PumpMechanics
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