Download - Quality Control WP1

Marker compound

Finding the profile of active molecules in plant

Copyright 2010 All Rights Reserved, GP-TCM Consortium.

Quality Control Issues relating to quality

Supply of materialExport of material (restrictions on samples being taken out of China: clarity of permits needed)Substitutes /adulterants

1232763242008-2009

Taxonomic compounds 3D representation of LC-MS profileActive compoundsKite/Simmonds et al. unpublished


Supply: quality control Obtaining supply of quality plants

Urgent need to do this

This links with International Conventions EU Directives - D 1.9 Target audiences need different information

Business as usual is not an option.

What does this mean for conservation and those interested in increased use of biodiversity, improved agriculture, - research?

Changes in land use in China having impact on land available for growing plants = move from wild harvesting to cultivated materialOctober 30 2006

Global Strategy for Plant Conservation

Conservation and sustainable use of plants used in TCMAdopted World Summit 2002 16 targets to deliverTargets revised Dublin Ireland 2010

TCM: and GSPCMain areas of activity internationally:Target 1: A widely accessible working list of known plant spp., as a step towards a complete world flora Target 2: A preliminary assessment of the conservation status of all known plant spp.Target 8: 60% of threatened plant spp. in accessible ex situ collections, preferably in country of origin, and 10% included in recovery and restoration programmes

Plant conservation in China33,000 vascular plants (50-60% are endemic: e.g. Camellia 98 in China, 21 in rest of the world) of which 24,667 are represented in botanical collections in China

Red listed species: 1992=388; 2004 = 4408 (TCM 500)

3,000 natural conservation area (16% of land area; 1980=70; 2010=160 botanic gardens)

Plant Biodiversity in ChinaCrop plants: 300 of the 15,000 crop plants come from China

Ornamentals: 60% of the 7,500 traded come from China

Medicinal: 8000 species about 2000 TCM

Target 12: Managing plant products sustainablyProgress Health Agriculture WP 1

ImplementBiodiversity StrategiesSustainable Development StrategyGAP guidelines - TCM Forestry Standards, Organic Action plansBest practise LEAF (Linking Environment & Farming)CAP reforms cross compliance, Natura 2000 network


What information are we gathering NamesWhere plants are growingHow they are grownAre they processed/howChemisty (as to above)Chemistry and activity (often still needs to be done)Single species to mixture - the real TCM


Plant names Legacy of GP-TCM

Wellcome Trust grant 685,850 over 3 yrs

List scientific names, trivial names, trade names and CAS numbers etc


Key points

Links with other WPs - bring the data together

Quality control criteria for reviewing papers and input into the future = SOP

Are we gathering the appropriate information ???

********