1. 1 | P a g e Prostate , , , , , , , - - , , : : 30 4 32 700 700 20 "One who stands before" "Protector" "Guardian" 2002 (Female Paraurethral Glands or Skene's Glands) (Orgasm) ... ( Exocrine) 20 3 .., 4 .. 2 .. (Pubic Symphysis) , , (Urinary Bladder) (Rectum) (Apex) (Striated External Urethral Sphincter)

2. 2 | P a g e , , (Fascia) (Anterior and Anterolateral Fascia) ( Penis) (Deep Dorsal Vein) (Denonvilliers) (RrectoVesical Fascia) (Connective Tissue) seminal vesicles (PuboProstatic Ligaments) (Levator Ani Muscle) 6 .. (Ductus Deferens) (Ejaculatory Duct) 3. 3 | P a g e 1- (Anterior lobe) 2- (Posterior lobe) 3- (Lateral lobes) 4- (Median lobe) 1968 . 1- (Transition zone) 2- (Central zone) 3- (Peripheral zone) 4- ( Anterior Fibromuscular Zone) (Glandular Tissue)10 % 20 % 70% 30% (Fibromuscular Stroma) (Transition zone) (Urethra) (2.5 ..) (2 ..) ( Posterior Urethera) (Epithelium) (Transitional) ( Adenoma) (Lateral Lobes) (Median Lobe) (Urethral crest) , ( Sinus or Grove) , - (Seminal Colliculus Verumontanum) , , (Prostatic Utricle) , 4. 4 | P a g e (Central zone) 25 % 2.5% , (Peripheral zone) 70% ( Per Rectal Examination) 70 % (Chronic Prostatitis) Anterior Fibro-muscular Zone (or Stroma) (5%) (Inferior Vesical Artery) , Internal Iliac (Hypogastric) Artery , , (Urethral Artery) , - 5 7 (Benign Prostatic Hyperplasia) , - (superior Vesical Artery) (Artery of the ductus) (Deep Dorsal Vein) , , 5. 5 | P a g e - (Anterior Prostatic Fascia) (Endopelvic Fascia) , , (Internal Iliac Vein) (S2-S4) , ( L1-L2) 7 .. , (PreProstatic Sphincter) ( ) - - , , (Transitional Epithelium) (Urethra) , 6. 6 | P a g e (Urethra) (Prostatic Urethra) , (Trigone) , (Membranous Urethra) (Penile (Cavernous) Urethra) (External Urethral Meatus) 3 . . 9 .. 30 .. (Stereocilia) , , (Peristaltic Waves) (Epididymis) (Ampulla) , 7. 7 | P a g e 20 (Acini) , (PSA) ( PSA) - -3 kallikrein-3 (KLK3) -3 (KLK3 gene) (Arousal) - (Orgasm) (Urethra) (Coiled) (Greek: upon + testicle) (Vas Deferens) ( ) , , - 1.028 (pH) 7.35-7.50 3 0.15 (2-5%) - 200-500 1.5-2 ( 65-75%) (1.5-6.5 /), , ,, , , , , 0.6-0.9 (25-30%) (PSA), , , , , , , , (13540 /) < 0.15 (10-20 ng/ml) - ( ) .. ... - .. ... , (Lymph Nodes) , , ... , (Cystoscopy) - (Cystoscopy) , , 15. 15 | P a g e (Staging) , I - II I ... III IV - 2002 ... ( Tumor, Node, Metastases) (T stage) , (N stage) (M stage) ... ("T") Tx: T0: T1: T1a: 5% T1b: 5% T1c: ... T2: T2a: T2b: , T2c: T3: T3a: T3b: T4: 16. 16 | P a g e T2c T2c ("N") NX: N0: N1: ("M") MX: M0: M1: M1a: M1b: M1c: , 17. 17 | P a g e , 1- 2- ( 3- -, , , , , - , , 36 % - 90 % , , (30%-70% ) (3%-10% ) - (Incontinence of Urine) (Impotence) 98% 60% , 70 % , , - 18. 18 | P a g e , 8 (), () - , 19. 19 | P a g e (Conventional External Beam Radiotherapy EBRT) 6 7 (Brachytherapy) , , , - , (Androgenic) ( ) LH-RH (Luteinizing Hormone-Releasing Hormone) - LH-RH LH-RH - - - ( Gynecomastia) (Hot Flashes) LH-RH (Lupron) (Zoladex) - (Eulexin) (Casodex) LH-RH 20. 20 | P a g e LH-RH , - ( ) 10 % () (Cryotherapy) (Cryotherapy) , (Fistula) ( () )HIFU HIFU , 800 -1000 C ... , (Emcyt) ( Castrate-Resistant Prostate Cancers) (Taxotere) , 21. 21 | P a g e , , , - ( ), - () ( ) http://www.virtualmedicalcentre.com/treatment/cryotherapy-for-prostate-cancer/93