demography and linked selection in maize and teosinte
Jeffrey Ross-Ibarra @jrossibarra
UC Davis
photo by Jason Wallace
Beadle 1979 Field Museum of Natural History Bulletin
Meyerowitz 1994 Current Biology Duvick et al. 1999 US 6639132 B1
maize origins
Tripsacum extinct maizeF1F1
teosinte (Z. mays ssp. parviglumis)
maize (Z. mays ssp. mays)
George Beadle
van Heerwaarden 2011 PNAS Matsuoka et al 2002 PNAS
Zea mays ssp. parvgilumis
Zea mays ssp. mexicana
Zea mays ssp. mays
1250m
M. D. PURUGGANAN AND D. Q. FULLER
Figure 4. Comparison of evolutionary rate estimates. Box plots of the rates of evolution in (A) log (darwins) and (B) log (haldanes) fordomestication (DOM) as well as plants (PLAN) (from Bones and Farres 2001) and anthropogenic (AN) and natural (NAT) conditions for wildanimal species (Hendry et al. 2008). The asterisk indicates domestication rates under the assumption of the shortened 2000-year periodfor legume species. The vertical lines give the estimate ranges, whereas the boxes span the minimum and maximum quartile range. Thehorizontal line within the box gives the median rate.
while for grain/seed increase is 0.68 ± 0.15 × 10−3 haldanes.Using the log (rate) estimates, we find that the evolutionary ratesare not significantly different (t = 0.63, df = 18, P < 0.54). Incontrast, however, making the assumption of an ∼2000-year do-mestication period for legumes leads to a nearly twofold higherestimate for grain/seed size increase across all species (mean =1.15 × 10−3 ± 0.26 haldanes), but this rate difference betweennonshattering and seed size increase is still not significant (t =0.34, df = 18, P < 0.74). This analysis does not reveal a sig-nificantly higher rate for nonshattering compared to grain sizeevolution.
EVOLUTIONARY RATES DURING DOMESTICATION
ARE SIMILAR TO THOSE EXPERIENCED BY WILD
SPECIES
The real interest in calculating evolutionary rates for these dif-ferent domestication traits lies in the comparison with estimatesobserved in wild species that are subject to natural selection. Therehave been extensive compilations of phenotypic rates of evolu-tion from contemporary microevolutionary (Hendry and Kinnison1999; Bone and Farres 2001; Kinnison and Hendry 2001; Hendryet al. 2008) and paleontological data (Gingerich 2001), and wecan use these to compare domesticated versus wild species.
The rate estimates for evolution during domestication fallwithin the range observed in these microevolutionary studies, buton the lower side of the range, either those for plants (Bone andFarres 2001) or under natural and anthropogenic conditions inanimals (Hendry et al. 2008,) see Figure 4. Comparison with theplant data (Bone and Farres 2001), for example, reveals that themean rates of evolution based on log-transformed data are muchhigher than those observed for the rate of evolution during domes-tication (see Fig. 4 and Table 4). Indeed, the mean evolutionaryrates we observe during domestication are significantly lower thanmean rates of phenotypic evolution of plant species in the wild(t = 7.48, df = 91, P < 0.0001).
Most of the studies that document rapid evolution in wildplant species, however, represent cases of very strong selection(e.g., growth in serpentine soils, herbicide resistance, Bone andFarres 2001). To examine evolution of other wild species, we alsocompare our results to data from wild animal species (Hendry et al.2008). Moreover, the large size of the dataset (Hendry et al. 2008)allows us to focus on allochronic data (e.g., change across a timeseries, which is comparable to the our archaeological data), and topartition the data for wild species into those that have experiencednatural versus anthropogenic conditions. This comparison is basedon the assumption that, in contrast to the compiled data from plantsunder strong selection pressures (Bone and Farres 2001), the ratesof evolution under less-stringent selective conditions are at leastbroadly comparable between plants and animals.
Not surprisingly, the mean rates of evolution for wild speciesunder anthropogenic conditions are higher than those under nat-ural conditions (see Fig. 4 and Table 4). Nevertheless, the meanrate of evolution under domestication is significantly lower than
Table 4. Mean rates of evolution.
Mean Rates Rate Rate×103
(darwins) (haldanes)
DomesticationOverall 144.56±33.55 0.73±0.14Overall1 200.82±44.04 1.17±0.26Nonshattering 835.44±196.13 0.98±0.16Grain/seed size 107.92±20.7 0.69±0.16Grain/seed size1 158.35±32.15 1.21±0.29
NaturalPlant 8893.8±2604.8 33.4±10.5Anthropogenic animal 5906.7±781 71.3±18.4Natural animal 626.2±86.4 29.5±5.4
1Rates calculated under the assumption that legume domestication occurred
over a 2000-year period.
1 7 8 EVOLUTION JANUARY 2011
log
Dar
win
s (e
/106
yrs
)
Purugganan and Fuller 2010 Evolution Benz 2009 Hist. Maize
Briggs et al. 2007 Genetics Wang et al. 2005 Nature
1 2 3 4 5
6 7 8 9 10
tb1gt1
Figure 1.Phenotypes. a. Maize ear showing the cob (cb) exposed at top. b. Teosinte ear with the rachisinternode (in) and glume (gl) labeled. c. Teosinte ear from a plant with a maize allele of tga1introgressed into it. d. Close-up of a single teosinte fruitcase. e. Close-up of a fruitcase fromteosinte plant with a maize allele of tga1 introgressed into it. f. Ear of maize inbred W22(Tga1-maize allele) with the cob exposed showing the small white glumes at the base. g. Earof maize inbred W22:tga1 which carries the teosinte allele, showing enlarged (white) glumes.h. Ear of maize inbred W22 carrying the tga1-ems1 allele, showing enlarged glumes. For highermagnification copies of f–h see Supplementary Information.
Wang et al. Page 10
Nature. Author manuscript; available in PMC 2006 May 23.
NIH
-PA Author Manuscript
NIH
-PA Author Manuscript
NIH
-PA Author Manuscript
tga1Figure 2 Map of parviglumis Populations and Hopscotch allele frequency. Map showing the frequencyof the Hopscotch allele in populations of parviglumis where we sampled more than 6 individuals. Size ofcircles reflects number of individuals sampled. The Balsas River is shown, as the Balsas River Basin isbelieved to be the center of domestication of maize.
as our independent trait for phenotyping analyses. SAS code used for analysis is available athttp://dx.doi.org/10.6084/m9.figshare.1166630.
RESULTSGenotyping for the Hopscotch insertionThe genotype at the Hopscotch insertion was confirmed with two PCRs for 837 individualsof the 1,100 screened (Table S1 and Table S2). Among the 247 maize landrace accessionsgenotyped, all but eight were homozygous for the presence of the insertion Withinour parviglumis and mexicana samples we found the Hopscotch insertion segregatingin 37 (n = 86) and four (n = 17) populations, respectively, and at highest frequencywithin populations in the states of Jalisco, Colima, and Michoacan in central-westernMexico (Fig. 2). Using our Hopscotch genotyping, we calculated diVerentiation betweenpopulations (FST) and subspecies (FCT) for populations in which we sampled sixteenor more chromosomes. We found that FCT = 0, and levels of FST among populationswithin each subspecies (0.22) and among all populations (0.23) (Table 1) are similar togenome-wide estimates from previous studies Pyhajarvi, HuVord & Ross-Ibarra, 2013.Although we found large variation in Hopscotch allele frequency among our populations,BayEnv analysis did not indicate a correlation between the Hopscotch insertion andenvironmental variables (all Bayes Factors < 1).
Vann et al. (2015), PeerJ, DOI 10.7717/peerj.900 8/21
Studer et al. 2011 Nat. Gen.; Vann et al. PeerJ 2015 Wills et al. 2013 PLoS Gen
T/TM/TM/M
T/TM/TM/M
A B
T/TM/TM/M
T/TM/TM/M
A B
3’ UTR
5’ control region
Hufford et al. 2012 Nat. Gen.
strong selection (s~0.015) on ~1,100 genes 11M maize-teosinte shared SNPs
3,000 fixed SNPs
Tim Beissinger
teos
inte
nuc
leot
ide
dive
rsity
mai
ze n
ucle
otid
e di
vers
ity
distance to nearest substitution (cM)
Tim Beissinger Wallace et al. 2014 PLoS Gen.
Hard sweeps?
Interpretation
Hard sweeps were not widespread during maize domestication
Hernandez et al., 2011
Sattath et al., 2011
Other species
9distance to substitution (cM)mai
ze n
ucle
otid
e di
vers
ity
Sattah et al. 2011 PLoS Gen.
nucl
eotid
e di
vers
ity
distance to nearest substitution (cM)
distance to nearest substitution (kb)
scal
ed d
iver
sity
Ne ~ 150,000 Ne ~ 10,000
Ne ~ 2,000,000 Ne ~ 600,000
Sattah et al. 2011 PLoS Gen. Williamson et al. 2014 PLoS Gen Hernandez et al. 2011 Science
Tim Beissinger
rela
tive
nucl
eotid
e di
vers
ity
distance to gene (cM)
teosinte Ne~150,000maize Ne~50,000
200-2000bp
Nordborg et al. 1996 Genetical Res.Tim Beissinger
het. selection (hs)deleterious mut. rate μ
recombination rB ⇡ e
�P
iµiti
(ti+ri(1�ti))2
B =
rela
tive
dive
rsity
distance to gene (M)
observedbest fit
maizeteosinte
teosinte 2Ns=1maize 2Ns=1
s (h=0.1)
Tim Beissinger
Fitness effects of new mutations
maize
3.6E-7
3.6E-9
teosinte
µ
t = hs 2.3E-7
6E-9
Kate Crosby Hearne et al. 2014 http://hdl.handle.net/11529/10034
4K samples ~1M SNPs
Ne ~106
CIMMYT 1984
49M ha of open-pollinated maize 22,000 plants/ha. Nc ~1012
min. 10 plants/ha to reseed Ne ~5 x 108
Tim Beissinger
0.05Na
Na
Na 3Na
nucl
eotid
e di
vers
ity
distance to gene (cM)
sing
leto
n di
vers
ity
distance to gene (cM)
Mexico highland6,000 BP
S. America lowland
6,000 BP
S. America Highland
4,000 BP
Mexico lowland
9,000 BP
Matsuoka et al. 2002; Piperno 2006 Perry et al. 2006; Piperno et al. 2009
Li Wang Hearne et al. 2014 http://hdl.handle.net/11529/10034
●
●
y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529y = 0.039 − 8.8e−07 ⋅ x, r2 = 0.0529
0.00
0.02
0.04
0.06
0 2000 4000 6000 8000geographical distance to Balsas Valley (km)
perc
enta
ge o
f pol
ymor
phic
sites
elevation100020003000
country_name●
●
●
Central AmericaMEXICOSouth America
Lowland Highland
NA
NB
NCN1 N2
N2P
tDtE
tF
NA
NB
NCN1 N2
N2P
tDtE
tF
tmex
Nmex
NA
NB
NCN1 N2
tDtE
tF
N3 N4
NC = αNA
N1 = βNC
N2 = (1-β)NC
N2P = γN2
NC = αNA
N1 = βNC
N2 = (1-β)NC
N2P = γN2
NC = αNA
N1 = β1NC
N2 = (1-β1)NC
N3 = β2N2
N4 = (1-β2)N2
N4P = γN4
tG
N4PLowland Highland mexicana
Meso-americaLowland Lowland Highland
Model IA Model IB Model II
Mesoamerica South America
Figure 2 Models of historical population size for lowlandand highland populations. Parameters in bold were esti-mated in this study. See text for details.
(Figure 2).We calculated the observed joint frequency distributions
(JFDs) using only the GBS data set due to its lower level ofascertainment bias. A subset of synonymous and noncodingSNPs were utilized that had � 15 individuals without missingdata in both lowland and highland populations and did not vi-olate HWE. A HWE cut-off of P < 0.005 was used for eachsubpopulation due to our under-calling of heterozygotes.
We obtained similar results under more or less stringentthresholds for significance (P < 0.05 ⇠ 0.0005; data notshown), though the number of SNPs was very small at P <0.05.
Parameters were inferred with the software �a�i (Gutenkunstet al. 2009), which uses a diffusion method to calculate an ex-pected JFD and evaluates the likelihood of the data assumingmultinomial sampling. We did not use the “full” model thatincorporates all four populations because parameter estimationunder this model is computationally infeasible.
Model IA This model is applied separately to both theMesoamerican and the S. American populations. We assumethe ancestral diploid population representing parviglumis fol-lows a standard Wright-Fisher model with constant size. Thesize of the ancestral population is denoted by NA. At tD gen-erations ago, the bottleneck event begins at domestication, andat tE generations ago, the bottleneck ends. The populationsize and duration of the bottleneck are denoted by NB andtB = tD � tE , respectively. The population size recovers toNC = ↵NA in the lowlands. Then, the highland populationis differentiated from the lowland population at tF generationsago. The size of the lowland and highland populations at timetF is determined by a parameter � such that the populationis divided by �NC and (1 � �)NC ; our conclusions hold if
we force lowland population size to remain at NC (data notshown).
We assume that the population size in the lowlands is con-stant but that the highland population experiences exponentialexpansion after divergence: its current population size is �times larger than that at tF .
Model IB We expand Model IA for the Mesoamericanpopulations by incorporating admixture from the teosintemexicana to the highland Mesoamerican maize population.The time of differentiation between parviglumis and mexicanaoccurs at tmex generations ago. The mexicana population sizeis assumed to be constant at Nmex. At tF generations ago, theMesoamerican highland population is derived from admixturebetween the Mesoamerican lowland population and a portionPmex from the teosinte mexicana.
Model II The final model includes the Mesoamericanlowland, S. American lowland and highland populations. Thismodel was used for simulating SNPs with ascertainment bias(see below). At time tF , the Mesoamerican and S. Americanlowland populations are differentiated, and the sizes of popu-lations after splitting are determined by �1. At time tG, the S.American lowland and highland populations are differentiated,and the sizes of populations at this time are determined by�2. As in Model IA, the S. American highland population isassumed to experience population growth with the parameter �.
Estimates of a number of our model parameters were avail-able from previous work. NA was set to 150,000 using esti-mates of the composite parameter 4NAµ ⇠ 0.018 from parvig-lumis (Eyre-Walker et al. 1998; Tenaillon et al. 2001, 2004;Wright et al. 2005; Ross-Ibarra et al. 2009) and an estimateof the mutation rate µ ⇠ 3 ⇥ 10
�8 (Clark et al. 2005) persite per generation. The severity of the domestication bottle-neck is represented by k = NB/tB (Eyre-Walker et al. 1998;Wright et al. 2005), and following Wright et al. (2005) we as-sumed k = 2.45 and tB = 1, 000 generations. Taking into ac-count archaeological evidence (Piperno et al. 2009), we assumetD = 9, 000 and tE = 8, 000. We further assumed tF = 6, 000for Mesoamerican populations in Models IA and IB (Piperno2006), tF = 4, 000 for S. American populations in Model IA(Perry et al. 2006; Grobman et al. 2012), and tmex = 60, 000,Nmex = 160, 000 (Ross-Ibarra et al. 2009), and Pmex = 0.2(van Heerwaarden et al. 2011) for Model IB. For both Mod-els IA and IB, we inferred three parameters (↵, � and �), and,for Model II, we fixed tF = 6, 000 and tG = 4, 000 (Piperno2006; Perry et al. 2006; Grobman et al. 2012) and estimatedthe remaining four parameters (↵, �1, �2 and �).
4
Lowland Highland
NA
NB
NCN1 N2
N2P
tDtE
tF
NA
NB
NCN1 N2
N2P
tDtE
tF
tmex
Nmex
NA
NB
NCN1 N2
tDtE
tF
N3 N4
NC = αNA
N1 = βNC
N2 = (1-β)NC
N2P = γN2
NC = αNA
N1 = βNC
N2 = (1-β)NC
N2P = γN2
NC = αNA
N1 = β1NC
N2 = (1-β1)NC
N3 = β2N2
N4 = (1-β2)N2
N4P = γN4
tG
N4PLowland Highland mexicana
Meso-americaLowland Lowland Highland
Model IA Model IB Model II
Mesoamerica South America
Figure 2 Models of historical population size for lowlandand highland populations. Parameters in bold were esti-mated in this study. See text for details.
(Figure 2).We calculated the observed joint frequency distributions
(JFDs) using only the GBS data set due to its lower level ofascertainment bias. A subset of synonymous and noncodingSNPs were utilized that had � 15 individuals without missingdata in both lowland and highland populations and did not vi-olate HWE. A HWE cut-off of P < 0.005 was used for eachsubpopulation due to our under-calling of heterozygotes.
We obtained similar results under more or less stringentthresholds for significance (P < 0.05 ⇠ 0.0005; data notshown), though the number of SNPs was very small at P <0.05.
Parameters were inferred with the software �a�i (Gutenkunstet al. 2009), which uses a diffusion method to calculate an ex-pected JFD and evaluates the likelihood of the data assumingmultinomial sampling. We did not use the “full” model thatincorporates all four populations because parameter estimationunder this model is computationally infeasible.
Model IA This model is applied separately to both theMesoamerican and the S. American populations. We assumethe ancestral diploid population representing parviglumis fol-lows a standard Wright-Fisher model with constant size. Thesize of the ancestral population is denoted by NA. At tD gen-erations ago, the bottleneck event begins at domestication, andat tE generations ago, the bottleneck ends. The populationsize and duration of the bottleneck are denoted by NB andtB = tD � tE , respectively. The population size recovers toNC = ↵NA in the lowlands. Then, the highland populationis differentiated from the lowland population at tF generationsago. The size of the lowland and highland populations at timetF is determined by a parameter � such that the populationis divided by �NC and (1 � �)NC ; our conclusions hold if
we force lowland population size to remain at NC (data notshown).
We assume that the population size in the lowlands is con-stant but that the highland population experiences exponentialexpansion after divergence: its current population size is �times larger than that at tF .
Model IB We expand Model IA for the Mesoamericanpopulations by incorporating admixture from the teosintemexicana to the highland Mesoamerican maize population.The time of differentiation between parviglumis and mexicanaoccurs at tmex generations ago. The mexicana population sizeis assumed to be constant at Nmex. At tF generations ago, theMesoamerican highland population is derived from admixturebetween the Mesoamerican lowland population and a portionPmex from the teosinte mexicana.
Model II The final model includes the Mesoamericanlowland, S. American lowland and highland populations. Thismodel was used for simulating SNPs with ascertainment bias(see below). At time tF , the Mesoamerican and S. Americanlowland populations are differentiated, and the sizes of popu-lations after splitting are determined by �1. At time tG, the S.American lowland and highland populations are differentiated,and the sizes of populations at this time are determined by�2. As in Model IA, the S. American highland population isassumed to experience population growth with the parameter �.
Estimates of a number of our model parameters were avail-able from previous work. NA was set to 150,000 using esti-mates of the composite parameter 4NAµ ⇠ 0.018 from parvig-lumis (Eyre-Walker et al. 1998; Tenaillon et al. 2001, 2004;Wright et al. 2005; Ross-Ibarra et al. 2009) and an estimateof the mutation rate µ ⇠ 3 ⇥ 10
�8 (Clark et al. 2005) persite per generation. The severity of the domestication bottle-neck is represented by k = NB/tB (Eyre-Walker et al. 1998;Wright et al. 2005), and following Wright et al. (2005) we as-sumed k = 2.45 and tB = 1, 000 generations. Taking into ac-count archaeological evidence (Piperno et al. 2009), we assumetD = 9, 000 and tE = 8, 000. We further assumed tF = 6, 000for Mesoamerican populations in Models IA and IB (Piperno2006), tF = 4, 000 for S. American populations in Model IA(Perry et al. 2006; Grobman et al. 2012), and tmex = 60, 000,Nmex = 160, 000 (Ross-Ibarra et al. 2009), and Pmex = 0.2(van Heerwaarden et al. 2011) for Model IB. For both Mod-els IA and IB, we inferred three parameters (↵, � and �), and,for Model II, we fixed tF = 6, 000 and tG = 4, 000 (Piperno2006; Perry et al. 2006; Grobman et al. 2012) and estimatedthe remaining four parameters (↵, �1, �2 and �).
4
Table 1 FST of synonymous and noncoding GBS SNPs
Mesoamerica S. America
Lowlands Highlands Lowlands Highlands
Mesoamerica Lowlands –
Highlands 0.0244 –
S. America Lowlands 0.0227 0.0343 –
Highlands 0.0466 0.0534 0.0442 –
be that the adaptive mutation occurs in a lowland area, sub-sequently migrating into the highlands. The calculation abovedoes not account for these points, but the approximation is quitegood, as verified by exact numerical calculation of the chanceof fixation of a mutation as a function of the location whereit first appears (see Figure A1); for theoretical treatment seeBarton (1987).
Migration It is harder to intuit a corresponding expressionfor the chance that an allele established by selection in onehighland population moves to the other.
For maize in the Andean highlands to have inherited ahighland-adapted allele from the Mesoamerican highlands,those Andean plants must be directly descended from highlandMesoamerican plants that lived more recently than the appear-ance of the adaptive allele. In other words, the ancestral lin-eages along which the modern Andean plants have inheritedat that locus must trace back to the Mesoamerican highlands.If the allele is neutral in the lowlands, we can treat the move-ment of these lineages as a neutral process, using the frame-work of coalescent theory (Wakeley 2005). To do this, we needto follow all of the N ⇡ 2.5⇥ 10
6 lineages backwards. Thesequickly coalesce to fewer lineages; but this turns out to not af-fect the calculation much. Assuming demographic stationarity,the motion of each lineage can be modeled as a random walk,whose displacement after m generations has variance m�2, andfor large m is approximately Gaussian. If we assume that lin-eages move independently, and Zn is the distance to the furthestof n lineages, then Zn
pm�2
(
p2 log n +
p2/ log n) with
very high probability (Berman 1964).Since this depends only on the logarithm of n, the number
of lineages, the practical upshot of this is that the most distantlineage is very unlikely to be more than about 6 times moredistant than the typical lineage, even among 10
7 lineages. Lin-eages are not independent, but this only makes this calculationconservative.
ResultsSamples and data
We sampled 94 maize landraces from four distinct regions inthe Americas (Table S1; Figure 1): the lowlands of Mesoamer-ica (Mexico/Guatemala; n = 24) and northern S. America
Table 2 Estimated parameters of population size model
Mesoamerica Model IA Model IB
Likelihood �5592.80 Likelihood �4654.79
NC 138,000 NC 225,000
N1 52,440 N1 171,000
N2 85,560 N2 54,000
N2P 85,560 N2P 54,000
S. America Model IA Model II
Likelihood �3855.28 Likelihood �8044.71
NC 78,000 NC 150,000
N1 75,660 N1 96,000
N2 2,340 N2 54,000
N2P 205,920 N3 51,300
N4 2,700
N4P 145,800
(n = 23) and the highlands of Mesoamerica (n = 24) andthe Andes (n = 23). Samples were genotyped using theMaizeSNP50 Beadchip platform (“MaizeSNP50”; n = 94) andgenotyping-by-sequencing (“GBS”; n = 87). After filteringfor Hardy-Weinberg genotype frequencies and minimum sam-ple size at least 10 in each of the four populations (see Materi-als and Methods) 91,779 SNPs remained, including 67,828 and23,951 SNPs from GBS and MaizeSNP50 respectively.
Population structure
We performed a STRUCTURE analysis (Pritchard et al. 2000;Falush et al. 2003) of our landrace samples, varying the numberof groups from K = 2 to 6 (Figure 1B, Figure S3). Most lan-draces were assigned to groups consistent with a priori popu-lation definitions, but admixture between highland and lowlandpopulations was evident at intermediate elevations (⇠ 1700m).Consistent with previously described scenarios for maize dif-fusion (Piperno 2006), we find evidence of shared ancestry be-tween lowland Mesoamerican maize and both Mesoamericanhighland and S. American lowland populations. Pairwise FST
among populations reveals low overall differentiation (Table 1),and the higher FST values observed in S. America are consis-tent with the decreased admixture seen in STRUCTURE. Ar-chaeological evidence supports a more recent colonization ofthe highlands in S. America (Piperno 2006; Perry et al. 2006;Grobman et al. 2012), suggesting that the observed differentia-tion may be the result of a stronger bottleneck during coloniza-tion of the S. American highlands.
Population differentiation
To provide a null expectation for allele frequency differentia-tion, we used the joint site frequency distribution (JFD) of low-
7
Table 1 FST of synonymous and noncoding GBS SNPs
Mesoamerica S. America
Lowlands Highlands Lowlands Highlands
Mesoamerica Lowlands –
Highlands 0.0244 –
S. America Lowlands 0.0227 0.0343 –
Highlands 0.0466 0.0534 0.0442 –
be that the adaptive mutation occurs in a lowland area, sub-sequently migrating into the highlands. The calculation abovedoes not account for these points, but the approximation is quitegood, as verified by exact numerical calculation of the chanceof fixation of a mutation as a function of the location whereit first appears (see Figure A1); for theoretical treatment seeBarton (1987).
Migration It is harder to intuit a corresponding expressionfor the chance that an allele established by selection in onehighland population moves to the other.
For maize in the Andean highlands to have inherited ahighland-adapted allele from the Mesoamerican highlands,those Andean plants must be directly descended from highlandMesoamerican plants that lived more recently than the appear-ance of the adaptive allele. In other words, the ancestral lin-eages along which the modern Andean plants have inheritedat that locus must trace back to the Mesoamerican highlands.If the allele is neutral in the lowlands, we can treat the move-ment of these lineages as a neutral process, using the frame-work of coalescent theory (Wakeley 2005). To do this, we needto follow all of the N ⇡ 2.5⇥ 10
6 lineages backwards. Thesequickly coalesce to fewer lineages; but this turns out to not af-fect the calculation much. Assuming demographic stationarity,the motion of each lineage can be modeled as a random walk,whose displacement after m generations has variance m�2, andfor large m is approximately Gaussian. If we assume that lin-eages move independently, and Zn is the distance to the furthestof n lineages, then Zn
pm�2
(
p2 log n +
p2/ log n) with
very high probability (Berman 1964).Since this depends only on the logarithm of n, the number
of lineages, the practical upshot of this is that the most distantlineage is very unlikely to be more than about 6 times moredistant than the typical lineage, even among 10
7 lineages. Lin-eages are not independent, but this only makes this calculationconservative.
ResultsSamples and data
We sampled 94 maize landraces from four distinct regions inthe Americas (Table S1; Figure 1): the lowlands of Mesoamer-ica (Mexico/Guatemala; n = 24) and northern S. America
Table 2 Estimated parameters of population size model
Mesoamerica Model IA Model IB
Likelihood �5592.80 Likelihood �4654.79
NC 138,000 NC 225,000
N1 52,440 N1 171,000
N2 85,560 N2 54,000
N2P 85,560 N2P 54,000
S. America Model IA Model II
Likelihood �3855.28 Likelihood �8044.71
NC 78,000 NC 150,000
N1 75,660 N1 96,000
N2 2,340 N2 54,000
N2P 205,920 N3 51,300
N4 2,700
N4P 145,800
(n = 23) and the highlands of Mesoamerica (n = 24) andthe Andes (n = 23). Samples were genotyped using theMaizeSNP50 Beadchip platform (“MaizeSNP50”; n = 94) andgenotyping-by-sequencing (“GBS”; n = 87). After filteringfor Hardy-Weinberg genotype frequencies and minimum sam-ple size at least 10 in each of the four populations (see Materi-als and Methods) 91,779 SNPs remained, including 67,828 and23,951 SNPs from GBS and MaizeSNP50 respectively.
Population structure
We performed a STRUCTURE analysis (Pritchard et al. 2000;Falush et al. 2003) of our landrace samples, varying the numberof groups from K = 2 to 6 (Figure 1B, Figure S3). Most lan-draces were assigned to groups consistent with a priori popu-lation definitions, but admixture between highland and lowlandpopulations was evident at intermediate elevations (⇠ 1700m).Consistent with previously described scenarios for maize dif-fusion (Piperno 2006), we find evidence of shared ancestry be-tween lowland Mesoamerican maize and both Mesoamericanhighland and S. American lowland populations. Pairwise FST
among populations reveals low overall differentiation (Table 1),and the higher FST values observed in S. America are consis-tent with the decreased admixture seen in STRUCTURE. Ar-chaeological evidence supports a more recent colonization ofthe highlands in S. America (Piperno 2006; Perry et al. 2006;Grobman et al. 2012), suggesting that the observed differentia-tion may be the result of a stronger bottleneck during coloniza-tion of the S. American highlands.
Population differentiation
To provide a null expectation for allele frequency differentia-tion, we used the joint site frequency distribution (JFD) of low-
7
Hufford et al. 2013 PLoS Genetics van Heerwaarden et al. 2011 PNAS Takuno et al. 2015 bioRxiv http://dx.doi.org/10.1101/013607
Mexico highlands Andean highlands
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●●
●
●●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●●
●●
●
●
●
●●●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●●●●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●●●
●
●
●
●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●●●
●●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●●
●
●●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●●●●●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●●
●
●
●
●
●
●●
●●
●
●●●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●●
●
●
●●●●
●
●
●
●
●●
●●
●
●●
●
●
●
●●●●●●
●●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●●
●
●
●
●●●
●●
●
●●●
●
●
●●●●●
●
●
●
●
●●
●●●
●
●
●
●●
●●●●●●●●
●
●
●
●
●●
●
●●
●
●●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●●●
●●●
●
●
●
●
●
●●
●
●●●●
●●
●●
●●●●●
●●
●●●
●
●●●
●
●●
●
●
●
●
●●●
●
●
●
●
●●●
●●
●
●●
●●
●
●
●
●●●
●●
●●
●
●
●
●
●●
●●
●●
●
●●●
●
●●●
●
●
●
●●●
●●
●●
●
●
●●●
●●
●●
●●
●●●
●
●
●●
●●
●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●●
●
●
●
●
●●●
●●●
●
●●●
●
●●
●
●●●●
●
●
●
●
●●
●●●
●
●●
●●
●
●
●●
●
●
●●●
●
●
●
●●●
●●
●
●●●
●
●●
●
●
●
●
●●
●●
●
●●●●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●●●
●●●
●
●
●
●
●●●●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●●
●●
●
●●
●
●●●
●●
●
●●
●●
●●
●●
●●
●
●
●
●●●●
●
●
●
●
●
●
●
●●●●●
●●●●
●
●
●
●●●●
●●●●●●●●
●●
●
●
●●●
●●
●
●
●●
●●
●●
●●
●
●
●
●
●●
●
●●
●
●●
●●●
●●
●
●
●●●
●
●●●●●
●●●
●
●
●●●
●
●
●●
●●●
●
●
●●●●
●●
●●
●●
●
●
●
●
●
●
●
●●●
●
●
●●
●●
●
●●
●●●
●●●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●●
●●
●●●●
●●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●●●●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●●●●●
●●
●
●●
●
●
●●
●
●●●
●
●●
●
●●
●●
●
●
●
●●
●●
●●●
●
●
●
●
●●
●
●
●
●●●
●
●●
●
●
●
●
●
●●
●●●
●●
●●
●
●●●
●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●●
●
●●
●●
●
●
●
●
●●●●
●
●
●
●●●
●
●●
●
●
●
●
●●
●
●●
●●
●●
●●●●
●
●●
●
●●●●
●●
●
●
●
●
●
●
●●●
●
●
●
●●
●●
●
●●●
●
●
●
●●●
●
●●
●●●●●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●●
●●
●●
●
●●
●●●
●
●●
●
●
●
●
●
●
●●
●●●●●●●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●●
●●
●●
●●●
●●●
●
●
●
●●
●
●
●
●
●●
●●●●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●●
●
●
●●●●
●●●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●●
●●●
●●
●
●●
●
●●●●
●
●
●
●
●●
●
●
●●●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●●●
●
●●●
●●
●●●
●
●●
●
●
●●●
●
●●
●●
●●
●
●●
●
●
●●●
●
●
●
●
●
●
●●
●●
●
●●●
●
●●
●●
●
●●
●
●●
●
●●●●●●
●
●
●●●●●
●
●
●
●
●●●
●
●
●●
●●●●●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●●●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●●●
●●
●●●
●
●
●●
●●
●●●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●●●●
●
●
●
●
●●
●●
●●●
●
●●
●●●
●●
●
●
●●
●
●●
●
●
●
●●
●
●
●●
●●
●
●●●●●●
●
●
●●●●●
●
●●
●
●
●
●
●
●
●●
●●
●●
●●●
●
●
●
●●●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●●
●
●●
●
●
●●●●●
●
●●●
●
●●●
●●●
●
●●●
●●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●●●●
●
●
●
●
●
●
●●
●●
●
●
●
●●●●
●●
●●
●●●
●
●
●
●
●●●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●●●●●●
●●●●●
●
●
●
●
●
●
●
●●
●●●●
●
●●●●
●
●●
●
●
●
●
●
●●
●●●
●●
●●
●
●
●●
●
●●
●
●
●●
●
●
●●
●●●
●
●
●
●●●
●
●●●●
●●
●●●●
●
●●●
●
●●
●
●●
●●●
●●
●
●●●●
●●
●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●●
●
●
●
●●
●
●
●●
●●
●
●
●●
●
●●
●
●●●
●
●●
●
●
●
●
●
●●●●●
●
●
●
●
●
●●●
●
●●
●●
●
●●●●
●●
●
●
●
●
●
●
●●●●●●●
●●●
●●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●●
●●●●
●●
●●●
●●
●●
●●●
●●
●●
●●
●●
●
●
●●
●
●●●
●
●●
●
●
●
●
●
●●●●
●
●●
●●
●
●
●●
●
●●●
●
●
●
●●●●●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●●
●●
●●
●●
●
●●●●
●●
●
●
●
●●
●
●
●
●
●
●
●●●●
●
●
●
●●●
●
●
●
●
●
●
●●●●●●
●●
●
●●●
●
●
●
●
●
●
●
●●
●
●●●●●
●
●●
●
●
●
●
●●
●●
●
●
●●●
●●●●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●●●
●
●●
●
●●
●
●●
●
●
●
●●
●
●
●●
●
●●
●
●●●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●●
●
●●
●
●●
●●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●●
●
●
●
●●●
●●
●
●●●
●
●●
●
●●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●●●●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●●
●●●
●
●●●
●
●
●
●
●
●●
●
●●
●
●●●
●
●
●
●●
●
●
●
●●
●
●
●
●●
●●
●●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●●
●
●●●
●
●
●
●●●
●
●
●●
●●
●
●
●●●●
●●●
●●
●●
●
●●
●
●●
●
●●
●
●
●
●
●●
●
●●●●●●●
●●
●
●
●
●
●●
●●●●●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●●●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●●●●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●●
●●
●
●
●●●●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●●●●
●●
●
●●
●
●
●●●
●
●
●●
●●●●●
●
●
●
●
●
●
●●
●●●●
●
●
●
●●●
●
●
●
●
●
●●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●●●
●●
●
●
●●
●
●
●●●
●●
●●●●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●●
●●●●●
●
●
●●
●●
●
●●●
●●●●
●●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●●●●
●●
●●
●
●
●●
●●●●
●
●●●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●
●●
●●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●●
●●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●●
●●
●●
●
●
●
●
●
●●
●●
●
●
●
●●
●●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●●
●●
●●●●●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●●
●
●●
●
●
●
●●●
●
●
●
●
●●●●
●●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●●●●●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●●
●●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●●
●●
●●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●●●●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●●
●
●●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●●●●
●
●
●●●●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●●
●
●●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●●●
●●
●●
●
●●
●●
●●
●
●
●●
●
●
●●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●●
●
●
●
●
●●●
●
●
●●
●
●
●●
●
●●
●
●●●
●
●●
●
●
●
●●●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●●●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●●
●●
●●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●●
●
●
●●
●
●●
●●
●●
●
●●
●
●
●
●
●
●●●●
●
●
●●●●
●
●
●
●
●●
●
●●
●
●●
●●●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●●●
●
●
●
●●●●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●●●
●
●
●
●
●
●●
●●●
●
●
●●
●
●●
●
●
●
●
●●
●●●
●●●●●
●●
●
●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●●●●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●●
●
●●●
●
●
●
●●
●
●●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●●●●
●
●
●
●
●
●
●●●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●●●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●●●●
●●
●
●
●●
●
●●
●
●
●
●
●
●●
●●
●●
●
●●
●●
●
●
●●
●●
●
●●
●
●
●
●
●●
●
●
●●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●●●
●●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●●
●
●●●
●
●●
●
●●
●●
●
●
●●
●
●●
●
●
●
●●
●●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●●
●
●●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●●●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●●●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●●●●
●●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●●●
●●
●
●
●
●●
●●
●
●
●●●●
●
●
●●●●
●
●
●●●
●●●●●●
●
●
●●●
●●
●
●
●●
●●
●●
●●
●
●
●
●
●
●
●●
●
●●●
●
●●●●
●
●●
●●●
●●
●
●●
●●
●
●
●
●●●●●
●●●
●
●
●
●●●●
●
●●
●
●●●●
●
●●
●
●
●
●
●
●●●
●●●
●
●●
●●●●●
●
●
●
●
●●●●●●
●●
●
●
●
●●●●●
●
●
●
●●●
●●
●
●●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●●●
●●●●
●
●
●●●●●●●●●
●
●
●
●●●●
●●●
●
●●
●●
●●
●
●
●
●
●
●●
●
●
●
●●●●
●
●
●●
●
●
●●●
●●
●●
●●●●
●●●
●
●
●
●●
●
●
●
●●●●●
●●●
●
●●●
●●●●●●●
●
●●
●
●
●
●
●●
●●●●●●●
●
●●
●
●
●
●
●
●●●●●
●
●●●
●●●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●●
●
●●
●●
●●●●
●●
●●●
●
●
●●●●
●●
●
●●
●
●
●●
●
●●●●
●
●●●
●●●●●
●●
●●
●
●
●●
●
●●
●
●
●
●
●●
●●
●●
●
●●●●
●●●●●●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●●●
●●
●●●●
●
●●●
●
●
●●
●●
●
●●
●●
●
●●●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●●●●●
●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●●●●
●
●●
●
●
●
●
●●
●●
●●
●●
●●●
●
●
●
●
●●
●
●●●●●●●●●
●●
●
●●
●
●
●
●
●
●●●●●●
●●
●●
●
●
●●●●
●
●●
●●●●
●
●
●●
●
●
●●●●●●●●
●
●●●
●●●
●
●●
●
●●●
●●●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●●●●
●●
●
●●
●
●●
●●●
●●●
●
●●●
●
●●
●
●
●●
●
●
●●
●●●
●●●●●●●●
●●
●●●
●●
●●●●●
●
●
●●●
●●
●●●
●●
●
●●
●
●●
●
●●
●●
●
●●
●
●
●●
●●
●
●●
●
●●
●
●
●●●●
●●
●
●
●●●
●
●
●
●●●
●●
●
●●●●●●
●●
●●●
●
●●
●
●●
●●●
●●●●
●●●●●●
●
●
●●●●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●●●
●
●
●●●
●
●
●
●●
●
●
●●
●
●
●●●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●●●
●
●
●
●
●
●
●●
●
●●●●●●
●●●●
●●●
●●●●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●●●
●
●
●●
●
●
●
●●●●
●
●
●●
●
●●●
●
●
●
●●●
●●
●
●●●●●●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●●●●
●●●●
●
●
●●
●
●
●●●
●●●
●●
●
●●●●●●
●
●●●●●
●●
●
●
●
●●
●●●●●
●
●
●●
●●●
●
●●
●●
●
●●
●
●
●
●
●●
●●
●●●●
●
●
●
●
●
●
●●
●●●
●
●●
●●●●●●
●
●●
●
●●
●
●
●
●●
●●●
●
●●
●
●●
●●●●
●●●
●
●●
●●
●
●
●●●
●
●
●●●●●●
●●
●●●
●●●
●
●●
●●
●
●
●●●
●
●●
●●
●●
●●●●
●
●●●
●
●●●
●
●
●●
●
●●●●●●●●●
●
●●●
●
●●●
●●●
●●
●●●●
●
●
●
●
●
●
●
●
●●●●
●●●●●
●●
●●
0.000
0.005
0.010
0.015
0.020
Andean SAlow MexHigh MexLow GuaHigh swUS
theta
factor(pop)AndeanGuaHighlandMexHighlandMexLowlandSA_LowlandSW_US
SAm Low
Gua High
SAm High
Mex High
Mex Low
SW High
nucl
eotid
e di
vers
ity
●●●●●●●
●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●
●●●●●●●●●●●●●●●
●●●●●●
●●●●●●●●●●●●
●
●●●●●●●●
●
●●●●●●●●●●●
●●●●●●
●●●●●
●
●
●
●
●●●●●●●●●●●●
●●●●●●●●●●●●●●●●●
●
●●●●●●●●●●●●●●●●●●
●●●●●●●●●
●●●●●●●
●●●●●●●●
●●●
●
●
●
●●●
●●●●●
●●●●●●●●●●●●●●●●●
●
●●●
●●●●●●●●●●●●●●●●●●
●●●●●●●●●●●●●
●●●●●
●●●●●●●●●
●●●●●●●●●●
●●●●●●●●●●
●●●●●●●●●
●●●●●●●●●
●
●●●●●
●●●●●●●●●●●●●●●●●●●●●
●●●●●●●●●●●●
●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●
●
●●●●●●●●
●●●●●●
●●●●●
●
●●●
●●●●●
●●●
●
●●●●●●
●●
●●●●●●●●●●
●●●●●●●●●●
●●●●●●●●●●●●●●●●●●●●●
●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●
●●●●●●●●●●●●●
●●●●●●
●
●
●●●●●●
●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●
●
●●●
●●●●●●●●●●
●●●●●
●●●●●●●●●●●●●●
●●●●●●●●●●●●●●●●●●●●●●
●
●●●●●●●
●●●●●●●●●
●●
●
●●●●●●●●●●
●●●●●●●●●●●●●●●●●●●●●●●●●●●●●
●●●●●●●●
●
●
●●●●●●●●●●
●●●
●●●●
●●●●●●●●●●
●●●●●●●●●
●
●●●●●●●●●●●●●●●●●●●●●●●●
●●
●
●
●●●●●
●●●●●●
●●●●●●●●●●●●●●
●●●●●●●●●●●
●
●●●●●●●
●●
●
●
●●●●●●●●
●●●●●●●●●●
●●●●●
●●●●●●●●●
●
●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●●
●●●●●●●●●●●
●
●●
●●●●●●●●●●●●●
●●●●●●●●●●●●●●●●●●●●●●●●●
●●●●●●●●●●●●
●●●●
●
●●●●●●●●
●
●●●●●●●●
●●●●●●●●●●
●●●●●●●●
●●
●●●●●●●●●●●●●●●●●●
●
●
●●●●●●●●●●
●
●
●●
●●●●●●●●●●●●●●●●●●●●●●●●●●● ●
●●
●
●
●●●●
●
●●
●
●●●●
●●●●
●●●
●
●
●
●●
●
●
●●●
●●
●●●●●
●●●
●
●
●
●
●●●
●●
●●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●●●
●
●●●●●●●
●
●
●
●
●
●
●●
●
●
●●
●●
●●
●
●
●●
●
●●
●
●●●●●
●●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●●●●
●
●●●
●
●
●
●
●
●
●
●●●●
●
●●●
●●
●
●●
●●
●
●●
●
●
●
●●
●
●
●●●
●●
●
●
●●●
●
●●
●●●
●
●●●
●
●
●●
●●●●
●
●
●●●
●●●●●●●
●●●●●●
●●●
●
●●
●
●●
●
●
●●●●●
●●
●●
●
●
●
●
●
●
●
●
●●●●
●●
●
●
●●
●
●
●
●●
●
●●●●
●●
●
●●●●●
●●●●●
●
●●●●
●
●
●
●
●●
●
●
●●
●
●●●
●
●
●
●●
●●
●●●
●●
●●●●
●
●
●●
●
●
●
●●●●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●●
●
●
●●●●
●
●●
●●
●
●●●
●
●●●●●
●●
●●●●
●●●
●
●
●●
●●●●●
●
●●
●
●
●
●●
●●●●
●●●●
●
●●
●
●
●●●●●
●
●
●
●●●
●
●●●
●●
●
●●●
●
●●●
●
●
●
●●●
●
●
●●
●
●●
●
●●●
●
●●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●●
●
●
●●
●
●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●●
●●
●●●
●●●●
●
●
●
●●●●
●●
●
●
●●
●
●
●
●●
●
●●●
●●●
●
●
●
●●●
●
●
●
●●●●●●
●
●
●
●
●
●
●
●●
●
●●●
●●●●●●●
●●●
●●●●
●
●●
●
●●
●
●●
●●●
●●●
●
●●
●
●
●
●●●
●●●●
●●
●●●
●
●
●
●●
●●
●
●
●●
●●●
●
●
●
●
●●
●●●
●
●
●●●●●
●
●●
●
●
●●●
●
●
●
●●●●
●
●
●
●
●
●
●●●
●
●
●●
●●
●●●
●
●
●●
●●
●
●●●
●●●
●
●
●●
●●
●
●●●
●●
●●
●
●●●
●
●
●●
●
●
●
●
●
●
●●●●
●●●
●
●●
●●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●●
●●●●●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●●●●
●
●
●
●
●
●
●●●
●●
●
●●●●●
●
●●
●●●
●●
●
●
●
●
●
●
●
●
●●●
●●●
●
●●●●
●
●
●●
●●●
●●
●
●●
●
●
●●
●●●●●●●●
●
●●●●
●●
●●
●●●●●●
●
●
●●●
●
●
●●●
●●
●●●●
●
●●●●
●●●●●●
●
●
●
●
●●
●
●
●
●
●
●●●
●●
●●●
●
●
●●
●●
●
●●
●
●●●●
●●
●
●
●
●●●●●
●
●●
●●
●●●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●●●●
●
●
●
●●●●●
●●●●●●●
●
●
●
●
●
●
●
●
●●●●
●
●
●●●
●
●
●
●●
●
●●
●●●
●●
●
●
●
●
●●●●●●
●●
●●●●
●
●
●
●
●●
●●
●
●●
●●
●●
●
●
●●●●
●●●
●
●
●
●●
●
●●●
●●●●●●
●
●●
●●●●●●●●
●●
●●●●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●●
●
●
●●
●●
●
●●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●●●
●
●
●
●
●●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●●
●●
●●
●
●●●●
●●●
●
●
●●
●
●
●●●
●
●●
●●
●●
●●
●●
●●●
●
●
●
●
●●●
●
●
●●●
●
●●●●●
●
●●
●●●●
●●●●●
●
●●
●●●
●●●●
●●
●
●●
●●●●●
●●●●
●●●
●●
●
●
●
●●●●●●●
●
●●●
●●●●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●●●
●
●
●●●●
●
●●●●
●
●
●●
●●●
●●
●
●
●●
●
●
●
●●
●
●
●
●●●●●●●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●●●●
●
●
●●
●
●●●
●●
●
●
●●
●
●
●
●●●●
●●●
●
●●●●
●
●
●
●
●●
●
●
●
●
●●●
●●
●●
●
●
●
●●●
●
●
●●
●●
●
●●●
●
●
●●
●
●
●
●●
●
●●●●●●
●●●●●
●●●
●
●
●
●●●●●
●
●
●●
●●
●
●●
●●●●●●●●●●●
●●●
●
●●
●
●
●
●
●●●●
●●
●●●
●●●
●
●
●
●
●●
●
●
●●
●
●
●
●●
●●●
●●
●●●
●
●
●
●
●
●
●●●●
●●
●
●●
●
●
●●
●●
●
●●
●
●●●●●●●
●
●●
●
●
●
●
●●●
●
●
●●
●●●●
●●●
●
●●●●
●
●●
●●●
●●●
●
●●●●●
●
●●
●●
●●
●
●●
●
●●
●●
●
●●●●●●
●●●
●
●●
●
●●
●●●●●●●●
●
●
●
●
●●●
●●●●
●
●
●●●●
●
●●
●
●
●●●●●●●●●●●
●
●●
●●
●
●
●●●●
●
●●
●●●
●●
●
●
●
●●●●
●●●●
●
●
●●●●●●●●●●●●●●●●●
●
●●●
●
●●
●
●
●●
●●●
●●●
●
●●●
●
●●●●
●
●
●
●
●
●●
●●
●●
●
●
●
●●
●
●●●
●●●
●●
●
●
●
●
●
●●●●
●
●●●
●
●
●●
●●
●
●●●
●
●●●●●
●
●
●
●●
●●●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●●
●●
●
●
●●●●●
●
●●●
●●●●●
●●●
●●
●●
●
●●●●
●●
●
●●
●
●
●●
●●●●
●
●
●
●
●
●●●●
●●●●●●
●
●
●●●
●●●
●
●
●●
●●●
●
●●
●
●●
●
●
●●
●
●●●
●
●
●●●●●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●●●
●
●
●●●
●●
●
●●
●
●
●●●
●
●●●●●●
●●
●
●
●●
●●●●●
●
●
●●●
●●●
●
●●●
●●●
●
●
●●●
●
●●
●●
●●●
●●●
●
●●
●●●●●●
●
●
●●●●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●●
●●
●
●
●●
●●
●
●
●
●
●
●●●
●
●●●●●●●●●●●●●●●●
●
●
●
●
●
●
●●●●
●
●
●
●●
●
●
●
●
●●
●●
●●
●
●●●●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●●●●●
●●
●●
●
●
●●●
●
●●●
●
●
●
●●●
●
●●
●●●
●
●●●●
●
●●
●●●●●●●●●●
●
●●●
●●
●
●
●
●●
●
●●
●●●●
●
●●
●●●●
●
●●●
●●●
●
●●
●●●
●
●
●
●
●
●
●●●
●●●
●
●
●
●●
●
●●●
●
●
●●
●
●●
●●
●●●
●
●●●
●●
●●
●
●
●
●●●●●●
●●●●
●●
●
●●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●●●●
●●●
●●●
●
●●
●
●
●
●
●
●●
●●
●●●●
●
●
●
●●●●●●
●
●
●●
●●●●●●●
●
●
●●●●●
●
●●●
●
●
●●
●●●
●
●●
●
●
●
●●●●●●●●
●●●
●
●
●●●●
●●
●●
●
●●
●●
●
●●
●
●
●
●●
●
●
●●
●
●
●●●
●●
●
●
●
●
●
●●
●
●●
●●
●
●●
●
●●
●●●●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●●●●●
●●
●
●
●
●
●●
●●
●
●
●
●
●●
●●●●
●
●
●
●
●
●
●
●
●
●
●●●●●●●●
●
●●
●●●
●
●●●
●
●
●●●●
●●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●●●●●●
●●
●
●
●●
●
●
●●●
●●
●●
●
●●
●
●
●
●
●●●
●
●●
●
●●●●●
●●
●●●●●●
●●●●●●
●
●
●
●●●●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●●
●
●●
●●●●●●●
●
●●●●
●
●
●
●●
●●
●
●
●
●
●●●
●●●
●
●
●●
●
●●●●●
●
●●
●
●
●
●●
●
●
●●
●
●
●●
●●
●
●
●●●●●
●●●
●●
●
●●
●
●●
●●
●
●●
●
●
●●●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●●●
●
●●
●
●
●●●
●●●
●●
●●
●●
●●
●
●
●●
●●
●●
●
●
●●
●
●
●●
●
●
●
●●
●
●●
●●
●
●●
●●●
●
●
●●●●●
●
●●
●●●●
●
●
●●
●
●
●●●
●●●
●
●
●
●●●●●●●●
●
●
●
●●●
●
●●
●●
●
●●
●●●
●
●
●●●●
●
●●●●
●
●
●●●●●
●
●
●
●
●
●●
●●
●●
●
●●
●●●
●
●●
●
●
●
●●●
●
●●●
●
●●
●
●●
●●●●●
●
●
●
●●●●
●●●
●
●
●
●
●
●
●
●●
●●
●
●●●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●●
●●
●
●
●
●●
●
●●
●●●
●
●
●
●●●●●●
●
●●●●
●●
●
●●●●
●
●
●●
●
●
●
●
●●●
●●●
●
●●●
●●●
●●●
●
●
●
●
●
●●
●●
●●●●●●●●
●●
●
●
●
●●●
●
●
●●
●
●●
●
●
●
●
●
●●●●
●
●●●
●
●
●
●●
●●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●●●
●●
●●
●
●●
●●
●
●
●●●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●●
●
●
●●
●●●
●●
●
●●
●
●
●
●●●
●
●●
●●●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●●●●●
●
●
●
●
●●
●
●●●●
●●
●
●
●●
●●●
●
●
●
●●●
●●
●●
●●●
●●
●
●●
●●
●●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●●●
●
●●●●
●●●
●●
●●
●
●●
●
●
●
●
●
●●
●
●
●●
●●●
●
●
●
●●
●●
●
●
●
●●●●
●
●
●●●●●
●
●●
●●
●
●
●
●●●
●●●●●●●
●●●●
●
●
●
●●
●
●●
●●●●●
●●
●
●●●●
●
●
●●
●
●●
●
●
●●
●●●
●●
●●●●
●●
●●
●●
●●
●
●●●
●
●
●
●●●●●●●
●
●
●
●●●
●
●
●
●●●
●●●●●
●
●●●
●
●
●●●●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●●
●●●●●
●●●
●
●
●●
●
●●●
●
●●
●
●
●●●●
●●
●●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●●
●
●
●●
●
●●●●●●
●
●
●
●
●
●
●
●
●●
●●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●●
●
●●
●
●
●
●●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●●
●
●
●
●●●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●●
●●
●
●
●
●
●●
●●●●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●●
●
●●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●
●
●
●●●
●
●
●●●
●
●
●●
●
●●
●
●
●
●
●●
●●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●●●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●●
●
●
●
●●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●●
●●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●●●●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●●●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●●●
●●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●●●●
●
●
●
●
●●
●
●●
●●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●
●
●●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●●
●
●●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●●
●●
●
●
●●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●●●●
●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●●
●●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●●
●●●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●●
●
●●
●
●
●
●
●●
●●
●
●
●●
●●●●
●
●
●●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●●●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●●
●●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●●●●●●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●●
●
●
●●●●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●●●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●●
●●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●●●
●●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●●●
●
●●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●●
●●●
●
●
●
●●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●●●
●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●●●●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●●
●●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●●●
●
●
●
●●
●
●
●
●●●●●●
●●●●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●●
●●
●
●
●
●●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●
●
●●●
●
●●
●
●
●
●
●
●●●●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●
●●
●
●
●
●
●
●●●●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●●
●●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●
●
●●
●
●
●
●●●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●●●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●●●
●●
●
●
●
●
●●
●
●●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●●
●
●
●
●
●●●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●
●●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●●
●
●●
●
●
●
●
●●●
●
●●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●●
●
●●
●●●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●●●
●●●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●
●●●
●●
●
●●
●
●
●
●
●●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●●
●●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●●
●●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●●
●●●
●
●
●●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●●●●
●
●
●
●
●
●
●●
●●
●●●
●
●
●●
●
●
●
●
●●●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●●
●●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●●●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●●
●●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●●
●
●●●●
●
●
●●
●
●
●
●
●●
●●
●
●●
●
●
●●
●●
●●●●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●●
●
●●●
●
●
●
●
●
●●●
●
●
●
●●●
●
●
●●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●
●
●●●
●
●
●
●
●●●●●●●●
●
●●
●
●
●●●●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●●●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●●●
●
●
●●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●●●
●●
●
●
●●
●
●●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●●●
●
●
●●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●●
●●
●
●
●
●●
●
●
●
●
●
●●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●
●
●●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●●
●●
●
●●
●
●
●
●●●
●
●
●
●
●
●●●●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●●
●
●
●●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●●
●
●
●●●
●●
●
●
●
●
●●
●●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●●●
●
●●●●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●●
●●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●●
●
●●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●●●●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●●●
●
●
●
●●●●
●
●
●
●
●
●●
●
●
●
●●●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●
●●
●
●●
●
●
●●
●●
●●
●
●
●
●●
●
●●●
●●
●●
●
●
●
●
●●
●
●
●●
●
●
●
●●●
●
●●●●
●●
●●●●●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●●●
●
●●●
●
●●
●
●
●
●●●
●
●
●
●
●●●
●●
●●
●●●
●
●
●●●●
●●
●●
●
●
●
●
●
●
●
●●
●●
●
●●●
●●●
●
●
●
●
●●
●
●
●●
●●
●
●●●
●
●
●●
●●
●●
●
●
●●●
●
●
●
●
●●●●
●●●
●●
●
●
●●
●●
●
●
●
●
●●●
●
●
●●
●●
●
●●
●
●
●●
●
●●
●
●
●●
●●●
●
●●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●●●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●●●
●●
●●●
●
●
●●
●
●●●
●
●
●
●
●
●●●
●
●●
●●
●●
●
●●●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●●●●●
●
●
●
●
●●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●
●
●●●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●●●
●
●
●
●
●
●●●
●●●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●●
●●●
●●●●
●
●
●●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●
●
●●●
●●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●●●
●
●●
●
●●●●
●
●
●●
●
●●
●●
●
●
●●●
●●
●●●
●
●●
●●
●
●
●●
●
●●
●
●●
●
●
●●●
●●●●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●●●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●●
●
●
●
●
●
●●●●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●●
●●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●●
●
●
●
●
●
●
●
●●
●
●
●●●●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●●●
●
●●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●●●●●
●
●●
●
●
●
●●
●
●●
●
●●●●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●●
●
●
●
●●●
●●●●●●
●●●
●●
●●
●
●●
●●●●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●●
●●●
●
●
●
●
●
●
●
●●
●
●●
●●
●●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●●●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●●●●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●●●
●
●●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●●
●
●●
●●
●
●●
●
●●
●
●
●●●
●
●
●
●
●●
●
●
●●●
●
●
●●
●
●
●●
●
●
●
●
●
●●●●●●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●●
●●
●
●
●
●
●
●●●●
●●●
●
●●●●
●
●
●
●
●
●
●
●
●
●●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●●●●●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●●
●
●
●●
●
●
●●
●
●
●●
●
●
●●
●
●●
●
●
●●
●
●
●●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●●
●
●
●●
●
●
●
●
●●●●
●
●
●
●●●
●●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●
●●
●
●
●●●●
●●
●●
●
●●●
●
●
●●
●●
●
●●
●●
●
●●
●
●
●●
●●
●
●
●
●
●●
●●
●
●
●●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●●●
●●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●●
●
●●●●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●●●
●●●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●●●●●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●●●
●
●●●
●
●
●
●●●●
●
●
●
●●●●●●●
●
●●●●●
●●
●
●●●
●
●●
●
●●●●
●
●
●●
●●
●
●●●●
●
●●●
●
●
●●●●
●
●●●
●
●
●
●●●
●
●
●
●
●
●●
●●
●●
●●
●
●●●●●●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●●●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●●
●●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●●●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●●
●
●●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●●
●
●●
●
●
●
●●●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●●●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●●●●●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●●●●
●●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●●●
●●●●
●
●
●
●●
●
●●
●
●
●●
●
●
●●
●●●●
●
●●●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●●
●●
●
●●●●
●
●
●
●
●●●●
●
●●
●
●●●
●●
●
●
●●
●
●
●
●●●
●●
●●
●●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●
●●
●
●
●●
●●●●
●●
●
●
●●●
●●
●●
●●●
●
●
●
●
●
●●●
●
●
●
●●
●●●
●
●●●
●
●●
●
●
●
●
●●
●
●
●●
●●●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●●●●
●●
●●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●●
●●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●
●●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●●●
●●●●
●
●
●
●
●
●
●●●
●●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●●
●●
●●
●
●
●●●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●●●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●●●
●●
●
●
●
●●●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●●●
●●
●●
●
●●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●●●●●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●●
●
●●
●●
●●●
●
●●
●
●●
●
●
●
●
●●
●●●
●●●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●●
●
●●
●●
●
●●
●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●●●●
●
●
●
●
●
●
●
●●●●●●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●●●●
●
●●●
●●
●
●
●
●
●
●●●●
●●●●●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●●
●●
●●
●●●
●●●●●
●
●
●●●
●
●●
●
●●
●●
●●●●
●
●
●●
●●●
●
●
●
●●
●●
●
●●●
●
●
●
●
●
●●●●
●
●
●
●●●●
●
●
●
●●
●●●
●●●
●
●
●●●●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●●●
●
●●●●
●
●
●●
●●●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●●●●●
●
●●
●●●
●●
●●●
●●●●●
●
●
●●
●
●
●
●●●●●●
●●●
●●
●
●
●●
●●●
●
●
●●
●●
●●●
●
●●
●●
●
●
●
●●
●
●●●
●●
●
●
●
●●
●●
●●●●●●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●●
●
●●
●●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●●
●
●●
●
●●
●
●●
●●●●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●●
●●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●
●●
●●
●●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●●
●
●●●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●●●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●●
●
●
●
●●●●
●
●●●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●●
●
●●
●●
●
●
●
●●
●●
●
●●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●●●
●
●
●●●●●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●●
●
●
●
●
●●●
●
●
●●
●
●
●●●
●
●
●
●
●●
●
●
●●●●
●
●●
●
●
●●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●●
●●
●
●
●●●
●
●
●
●●
●●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●●●
●
●
●
●
●
●●
●
●
●●
●
●●
●
●●●●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●●●
●●
●●
●
●●
●
●
●●
●●●
●
●
●
●●●
●●●●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●●
●●
●
●●●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●●●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●●●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●●●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●●●●
●
●
●
●
●
●●
●
●
●
●●
●●●●
●
●●
●
●●
●
●
●●●
●●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●●●●●
●
●
●●●
●●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●●●●●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●●
●
●●
●
●
●●
●
●
●●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●●
●
●
●●●
●●
●
●●●●
●●●
●
●●●●●
●
●
●●
●●
●
●
●●●
●
●●
●
●
●
●
●
●●
●●●●
●●
●●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●●●●
●
●●
●
●
●●
●
●●
●
●
●
●
●●●
●●
●●
●
●●●●
●●●
●
●
●●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●●●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●●●
●
●●●
●
●●●●●●●●●●
●●
●●●
●●
●●
●●●
●
●
●●
●
●●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●●
●
●
●●
●
●●●
●
●
●●●
●
●
●
●
●●●●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●●●
●●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●●
●●●●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●●
●●●
●
●
●●
●
●
●
●
●
●●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●●●●
●
●●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●●●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●●
●
●●●
●
●
●●
●●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●●
●●
●
●
●●●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●●
●●
●
●●●
●
●
●
●
●●
●●
●
●
●
●●
●
●●
●●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●●
●●●●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●●
●
●
●●
●
●
●
●
●●
●●
●
●●●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●●
●
●●
●●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●●●●●●●
●
●
●
●
●
●
●●
●●
●●
●●
●●
●
●
●●●
●
●●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●●
●
●●
●
●
●●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●●
●●
●●●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●●
●
●
●
●●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●●●
●
●●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●●●●
●●
●
●
●
●
●●
●
●●
●
●
●
●●
●●
●
●
●●●
●●
●
●
●●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●●●
●
●
●
●
●
●●●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●●
●
●
●●
●●●
●
●●
●
●
●
●●
●
●
●●
●●
●●
●
●
●
●
●●
●
●●
●●
●
●
●●
●●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●●●
●●●
●●
●
●●
●
●
●
●
●
●●●●●●
●
●
●●
●
●
●
●
●
●●●
●●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●●●
●
●●●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●●●
●●
●
●
●
●●
●●●
●
●●●●
●●
●●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●●●●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●●●●
●●
●
●
●
●
●
●●
●
●●
●●●●
●
●
●
●●
●●●●●●●●
●●
●
●●
●
●
●●●●
●●●●
●
●
●●
●
●
●
●
●
●
●
●●●●
●●●
●●●●●
●
●
●
●
●●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●●
●
●●●
●
●●●●●●
●●
●●
●
●
●
●
●●
●
●●
●●
●●
●
●
●
●●●●●
●
●
●●●
●●●
●●●
●●
●
●
●●
●
●●●●●
●
●●
●
●
●
●
●●●●●●●●
●
●●
●
●●
●●
●
●●
●●
●●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●●●●●●
●
●●●
●●
●
●●●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●●●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●●●
●●●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●●
●
●●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●●
●●
●●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●●●
●
●
●
●●
●
●●
●●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●●●
●●●●
●●
●●●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●●
●●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●●●
●●
●
●
●
●●●●
●
●
●
●
●
●
●●
●
●
●
●●●●
●
●●
●
●
●●
●
●
●
●
●●●●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●●
●●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●●●●●
●
●
●
●
●
●●
●●●●●
●●
●
●
●
●
●●
●
●
●
●●
●●
●●
●●●●
●●
●●●
●●
●
●
●
●
●●
●●
●
●
●●
●●
●
●●●
●
●●
●
●●
●
●
●
●
●
●●
●●
●●●●●
●
●
●●
●
●●
●
●
●●●
●●
●●●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●●
●●
●
●
●●●●
●●
●
●
●●●
●●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●●
●●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●●●●
●
●
●●●
●●
●
●
●
●
●
●●●
●
●
●●
●
●
●●
●
●●
●
●
●●●
●●
●
●●
●
●
●●●
●
●
●●●
●●
●●●
●●
●
●
●
●●
●●●
●
●
●
●●
●●●●
●
●●●
●
●
●
●
●
●●●●●●●●
●
●●
●●●●
●
●
●
●●
●
●
●●●
●
●●
●
●●●
●●
●●●●●
●●●●●●●
●
●
●
●
●●●
●●
●
●
●
●
●●
●●●
●
●
●●
●
●
●●●●
●
●
●
●●●
●●
●
●●
●●
●
●●
●
●●
●
●
●●
●●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●●
●
●●●
●●
●●●
●
●●
●
●●
●
●
●
●
●
●
●
●●●
●●
●●
●●●
●●●
●
●●
●●●●
●
●●
●
●
●
●●●●●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●
●●●
●
●
●
●
●
●●
●
●
●●●
●●
●
●
●
●
●
●
●●●
●
●●
●
●●●
●
●
●
●●
●●
●●●●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●●●
●●
●●●●
●
●●●
●
●●
●●●●
●●
●
●●●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●●
●
●
●●
●
●●
●
●
●
●●
●●
●●
●
●●
●●●●
●
●
●
●
●
●
●●●
●●●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●●●
●
●
●●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●●
●●
●
●
●
●●
●
●●●
●●●
●●
●●
●
●
●●●●
●●
●●
●
●
●●●
●●
●●
●
●●
●
●
●
●
●
●●●
●
●●●
●
●●●
●●
●●
●
●
●
●
●●
●
●●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●●
●
●●
●●
●●●●
●
●
●
●●●
●
●●
●
●
●●
●●●●
●
●●
●
●
●●
●●●●●
●
●●
●
●
●
●
●
●
●
●●
●●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●●●●
●●●
●
●
●
●
●
●
●
●●
●●
●●●
●
●
●●
●
●●
●●
●
●
●
●●●
●●●●●●●
●●
●
●
●
●●●
●
●
●●
●
●
●●
●
●
●
●●●
●
●●●●●●●●●●●●●●●●●●●●●●●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●●●●
●
●●●●●●
●
●●●
●
●●●●
●●●●●
●
●
●
●
●●●
●
●
●●●●
●●●
●●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●●●
●●●●
●●
●
●●●
●
●
●
●
●
●●●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●●●
●
●●●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●●●
●
●
●●
●
●
●
●●
●
●●
●
●●●
●
●
●
●●
●
●●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●●
●
●●●
●●
●
●●
●●●
●●
●●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●
●●
●
●●
●
●
●●
●●●
●
●
●●●
●●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●●
●●
●
●
●
●
●●
●
●●
●
●●
●
●●●
●●●●●●●
●●
●
●
●
●●●
●●
●●
●
●●
●
●
●●●
●
●●
●
●●●●
●●
●
●
●
●●
●●●
●●●●
●
●
●●●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●●●
●
●
●●●
●●
●
●
●●●
●
●
●●●●●●
●●
●
●
●●●●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●●
●
●
●●●
●
●
●
●●
●
●
●●●●●
●
●
●
●
●●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●●
●●●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●●●
●
●●
●●●●●
●●●
●
●●
●
●●●●●
●●
●●●
●
●●●
●
●
●
●
●●
●
●
●●
●●
●●
●●●●●●
●
●●●
●
●
●
●●●●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●●
●
●●●●
●
●●
●
●
●●
●
●●
●
●
●
●●
●
●●
●●●
●
●
●●
●●●●
●
●
●
●●
●
●●
●●
●●●
●●
●
●●
●
●
●●●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●●
●
●●●
●●●
●
●
●●
●
●●●
●●●
●●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●●●
●●●●●●●●
●
●●
●●●●
●
●
●●●
●
●
●
●
●
●
●
●●
●●
●●●●●
●
●
●
●
●●
●●●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●●●
●●
●●●●
●
●●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●●●
●●
●●
●
●●●
●●
●●●●
●●
●
●
●
●●
●●
●●
●●
●
●
●●
●●●
●●
●
●●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●●
●●●●●
●●
●●
●●
●
●
●●
●●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●
●●
●
●●●●
●●
●●
●
●●●●
●●●
●●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●●●●
●
●●
●
●
●
●
●
●
●●●●
●●●
●
●
●●
●
●
●
●
●●
●●
●
●●●
●
●
●
●
●
●
●●●●●●
●●
●●
●
●●
●●●●●
●
●
●●
●
●
●
●●
●
●
●●●●
●●●
●●
●●●
●●●
●
●
●●
●●●
●●
●
●
●
●
●●●●
●●
●
●●
●
●
●●●
●
●
●
●
●●
●●
●
●●
●
●
●●
●●
●
●
●
●●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●●
●
●●
●
●●
●
●●
●
●
●
●●
●
●●●●
●●
●●●●
●
●●
●●●●
●●●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●●
●
●●
●●
●●
●
●
●
●●
●
●
●
●
●●
●●●
●
●●
●●●●
●
●●
●●
●
●●
●●●●●
●●●●
●
●
●●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●●
●●
●●●●
●
●
●
●●●
●
●
●●
●●
●
●
●●
●●
●●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●●
●●●●
●●
●
●●
●
●
●
●
●
●
●●
●●
●
●●●
●
●●
●
●●●
●
●
●
●
●
●●●●●
●
●●
●
●●
●
●
●
●
●●●
●●
●●
●●
●
●
●
●
●
●
●
●●
●●
●●●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●●
●●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●●●
●●
●
●
●
●
●●
●●
●
●
●
●
●●
●●
●
●●●
●
●
●
●●
●
●
●
●
●
●●●
●●●
●●
●●●
●●
●●
●
●
●●●
●
●●
●●
●
●
●●
●
●●●●
●●
●●●
●●●●
●
●
●
●
●
●
●●●●
●●●●●
●
●●
●
●
●●●
●
●●●●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●●
●●
●●●
●
●
●
●●
●●
●●
●
●
●●
●●●●
●●
●●
●●
●
●
●●●
●●
●
●●
●
●
●
●●
●●●
●●
●
●
●
●●●●
●●
●●
●
●●●
●
●●
●
●
●
●●●
●
●●
●
●
●●
●
●
●
●●
●
●●●●
●●
●
●●
●●●
●
●
●
●
●●
●●
●●
●●●
●●●●●
●
●
●●●●●
●
●
●
●
●●●●
●●●
●
●●
●
●
●●●●●
●
●
●
●●●●●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●●
●
●
●●●
●●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●●●
●
●
●●
●
●
●
●●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●●
●●●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●●
●
●
●●●
●●
●●●●
●
●●
●
●●
●●●●
●
●
●
●●
●
●●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●●●
●●
●●●●●●●
●
●
●●●●
●●
●●
●
●●●
●●
●
●●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●●
●
●●●
●
●
●
●●
●
●●
●●●●●●●●●●●
●
●
●
●
●
●
●●●●●●●●●●●●
●
●
●
●
●●
●●
●●●●
●
●
●
●●●●●●
●
●
●
●●
●●
●
●●
●
●
●●
●
●●●
●●
●
●
●●
●●●
●
●
●
●●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●●●●●●●●●●●●●●●●●●●
●●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●●
●
●●
●
●
●
●●
●●
●●●●●
●●
●
●
●●
●●
●●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●●●
●
●
●
●
●●
●
●●●
●●●●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●●●
●
●●
●
●
●
●●●●●
●
●
●
●●●
●●●
●●
●
●
●
●
●●
●●
●
●
●●
●
●
●●●●
●
●●
●●
●
●●●
●
●●●
●
●●
●
●
●●
●
●
●
●●
●●
●
●
●●
●●
●●●
●●●
●
●
●
●
●
●●
●●●
●
●●●
●
●
●●
●
●●●
●
●●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●●
●●●●●●●
●●●
●
●
●
●●
●●
●
●●
●●●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●●
●
●
●●
●●●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●●
●
●
●
●●●
●●
●
●
●
●
●●
●●●
●
●
●
●
●●●
●●●
●
●
●●●
●●
●
●
●
●
●
●
●●●
●
●●●
●
●
●●
●●
●
●
●●
●
●●
●
●●●
●
●
●
●●
●
●●●●
●
●●●
●
●
●●●
●
●●
●
●●
●
●●●
●
●
●
●
●
●
●●
●
●●●●
●●
●●
●
●
●
●●●
●
●●●●
●●
●
●
●
●
●
●●
●
●
●●
●●
●●●●
●
●
●
●●●●
●●●●
●●
●
●
●
●
●●●
●
●
●
●●
●
●●●●●
●●●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●●●●
●
●●
●
●●
●
●
●
●●
●
●
●●
●●
●●
●
●
●
●
●
●
●●●●
●●●
●
●
●●
●
●
●●
●
●
●
●●
●
●
●
●●●●
●●●
●●●
●●●
●●●
●●
●●●●
●
●●●
●●
●
●●
●
●
●●●●●
●●
●●●
●
●●
●
●●●
●
●●●●●
●●
●●
●●●
●
●●
●●
●
●
●
●
●
●●●
●
●●
●
●
●●●
●●
●
●
●●
●
●●
●
●●●
●●
●●
●●
●
●
●
●
●●●
●●
●●●
●
●
●
●
●●
●●●
●
●●
●●●●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●●
●
●●●
●●●
●
●●
●●
●
●●
●●
●
●●
●●
●●
●
●●
●●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●●
●
●
●●●●
●●
●
●
●
●●
●
●
●●
●
●●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●●●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●●●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●●
●
●
●
●●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●●
●
●●
●●●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●●●
●
●●
●
●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●●●
●
●●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●●●●
●●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●●
●●
●
●
●●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●●●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●●
●●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●●
●●●●●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●●
●●
●
●
●●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●●●
●
●
●
●●
●
●
●
●●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●●
●
●●
●
●●
●
●
●
●●●●
●
●
●
●●
●●
●
●●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●●●
●●
●●●●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●●●
●
●●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●●
●
●●
●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●●
●●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●●●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●●
●
●●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●●
●
●
●●●
●●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●●●
●
●
●
●●
●
●
●
●
●●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●●●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●●●
●
●
●●
●
●
●●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●●
●
●
●
●●●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●●
●
●
●
●
●
●●
●
●●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●●
●●
●
●
●
●
●●●●●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●●
●
●
●
●
●●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●●●
●●
●●
●
●●
●
●
●
●
●●
●
●●
●
●
●●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●●
●
●
●●
●●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●●
●
●
●●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●●●
●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●
●●●
●●
●
●
●●●●●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●●
●●
●
●●
●
●●
●●
●●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●●●●
●
●
●
●
●
●●
●●
●●
●
●●
●●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●●●●
●
●
●
●
●●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●●
●
●●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●●
●●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●
●
●●●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●●
●●
●●
●
●
●●
●
●
●
●●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●●
●●●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●●●●
●
●
●●
●
●●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●●
●●
●
●
●
●
●
●●●●●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●●
●●
●
●
●
●
●●
●
●●
●●
●●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●●
●●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●●●
●
●
●
●●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●●●
●
●
●●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●●
●●●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●●●●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●●
●●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●
●
●
●
●
●
●
●
●●●●
●
●
●
●
●
●
●●
●
●●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●●●
●
●●
●
●
●●
●●●
●
●
●●
●
●
●
●●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●●
●●
●
●
●
●●●
●●●
●●●
●
●
●
●●
●
●
●
●
●
●
●
●●●
●●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●
●
●
●
●●
●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●●
●
●
●●
●
●●
●
●●●
●●●
●
●
●
●
●
●
●●
●
●●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●●
●●●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●●●●
●●●●
●
●●●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●●
●
●●
●
●●●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●●
●●
●●
●
●●●
●
●
●
●
●
●
●
●
●
●●
●●●
●
●
●
●
●
●
●
●●●
●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●
●●
●
●
●●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●
●●
●●
●
●●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●●
●
●
●
●
●●
●
●
●
●
●●
●
●
●
●●
●●
●
●
●
●
●
●
●●
●●
●
●
●
●
●●●
●
●
●●
●
●
●
●
●
●
●●
●●
●●
●
●
●
●●
●
●
●
●
●
●
●●
●
●●
●
●
●
●
●
●●●
●
●●●
●
●
●
●
●
●●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●●●
●
●
●●
●
●●
●●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●
●●
●
●
●●●
●
●
●
●
●
●●
●
●
●
●−1
0
1
Andean SAlow MexHigh MexLow GuaHigh swUS
Tajim
aD
factor(pop)AndeanGuaHighMexHighMexLowSA_LowSW_US
Tajim
a’s D
SAm Low
Gua High
SAm High
Mex High
Mex Low
SW High
Rodgers-Melnick et al. 2015 PNAS
26
Figure S30. The mean GERP rates within annotated codons across the genome. Bars give the mean rates at all first and second codon positions or all third codon positions (red and orange bars) or the mean rates at those positions with known segregating polymorphisms (blue and green bars).
Figure S31. Percent difference between the proportion of polymorphisms at sites with GERP above a threshold in hotspots ( θ 1) vs. the rest of the genome (θ 2).
A B
N = 744,505 N = 506,898
r = -0.8
Mea
n G
ERP
Mea
n G
ERP
MAFchromosome
Jinliang Yang
Li Wang
●
●
●
●
●
1500000
2000000
2500000
3000000
Andes SA_Low MexHigh MexLow SW_US GuaHigh
load
popAndesGua_HighlandMex_HighlandMex_LowlandSA_LowlandSW_US
●
●
●
2500000
3000000
3500000
4000000
4500000
Andes SA_Low MexHigh MexLow SW_US GuaHigh
num
ber o
f var
iabl
e si
tes
with
GER
P >0
popAndesSA_LowlandMex_HighlandMex_LowlandSW_USGua_Highland
Variable(Sites(with(Posi0ve(GERP(
all deleterious (GERP>0) SNPsNon7reference(homozygous(sites(with(Posi0ve(GERP(●
●
●
●
190000
210000
230000
Andes SA_Low MexHigh MexLow SW_US GuaHigh
load
popAndesGua_HighlandMex_HighlandMex_LowlandSA_LowlandSW_US
●
●
●
200000
220000
240000
Andes SA_Low MexHigh MexLow SW_US GuaHigh
num
ber o
f non
Ref
hom
o si
tes
with
GER
P >
0
popAndesGua_HighlandMex_HighlandMex_LowlandSA_LowlandSW_US
pop Andes SA_Lowland Mex_HighlandMex_LowlandSW_US Gua_HighlandAndesSA_Lowland 0.0022Mex_Highland 0.0411 0.1201Mex_Lowland 0.004 0.2684 0.3961SW_US 0.0022 0.197 0.2424 0.5346Gua_Highland 0.0179 0.2738 0.131 0.1964 0.131
homozygous deleterious SNPs
SAm Low
Gua High
SAm High
Mex High
Mex Low
SW High
SAm Low
Gua High
SAm High
Mex High
Mex Low
SW High
Fu et al. 2014 AJHG
Paul Bilinski
2.50
2.75
3.00
3.25
3.50
3.75
MH ML SAH SAL mexicana parviglumis1C
Gen
ome
Size
(Gb)
Altitudehighland
lowland
• limited impact of (hard) sweeps on linked diversity
• strong role for background selection
• efficacy of selection in maize changed with Ne
• recent demography affects genetic load among populations
conclusions
Acknowledgements
Hufford Lab (Iowa State)Matt Hufford
Li Wang
Ross-Ibarra Lab (UC Davis)Tim Beissinger (USDA U. Missouri)
Kate CrosbyArun Durvasula
Graham Coop (UC Davis)
Top Related