*

pJN

K2/

JNK

2O

ptic

al D

ensi

ty

0.0

0.1

0.2

0.3

0.4

24 hpi6 hpi

Sham

Lesion

+Veh

Lesion

+Anti p7

5Sha

m

Lesion

+Veh

Lesion

+Anti p7

5Sha

m

Lesion

+Veh

Lesion

+Anti p7

5Sha

m

Lesion

+Veh

Lesion

+Anti p7

5

OVX OVX+E OVX OVX+E

* **

pJNK2pJNK1

JNK2JNK1

OVX ESTROGEN SHAM LESION LESION SHAM LESION LESION

+ VEH + P75 + VEH + P75

OVX ESTROGEN SHAM LESION LESION SHAM LESION LESION

+ VEH + P75 + VEH + P75

6 hpi 24 hpi