State of the art
Introduction to Neuro-Immunology
Dr. Abdallah El-Sayed AllamMSc of Physical Medicine, Rheumatology and Rehabilitation .
Faculty of Medicine. Tanta University. EgyptMSK US fellowship. National Taiwan University. Taiwan
Immune surveillance of CNS &Clinical Application
Clinical Application
Why do we need a control?
Concept of Metasystem
Immunologic Homunculus
Immunologic Homunculus
Concept of Metasystem
Why do we need a control?
Clinical Application
Immune surveillance of CNS
Clinical Application
• Nervous system controls Immune system via centers,
sympathetic, parasympathetic as well as endocrine
system
• T Lymphocytes trafficking is very important for immune
response.• BBB and peripheral immune reactions for the brain are
important in protection of the brain against many
immune reactions.• T Lymphocytes trafficking is a therapeutic target as MS
• Inflammatory reflex attenuates the inflammatory
response. Clinical application eg stroke and RhA
Thank You
Thank You
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