655
INDEX
Volume 216, January-March 1981
Abukhres, M. M., see Voilmer, R.
It, 580Acetaldehyde, effect on placental
valine uptake (rats), 465Acetylcholine, effect of reserpine
pretreatment on femoral ar-terial responses to (dogs), 447
levo-a-Acetylmethadol, and me-tabolites, effects on schedule-
controlled behavior (pi-geons), 299
Acivicin, sex- and age-relatedtoxicity and disposition of
(mice), 433
Acyclovir, pharmacokinetics and
bioavailability (dogs), 281Adenine nucleotides, involvement
in sympathetic nerves of bas-ilar artery (dogs), 401
Adenosine
effect of reserpine pretreatment
on femoral arterial responsesto (dogs), 447
effects on mechanical perform-ance and electrical activity in
heart (dogs), 254
S-adenosylmethionine adminis-tration, decreased cerebral
catabolism of [3B]histamineafter (mice), 118
Adenylate cyclase, in striatal tin-
sue, activation by ethanol(mice), 129
Adrenergic blockade, beta, effectson renal and splanchic bloodflows during nicotine infusion(dogs), 363
Adrenergic receptors (see alsoAdrenoceptors)
agonists and antagonists, ef-fects on vesicourethral
smooth muscle (rabbits), 95a�pha-2, in isOlated islets of
Langerhans (rats), 607
beta, in submaxillary glands,
changes after reserpine orisoproterenol (rats), 419
Adrenoceptors (see also Adrener-
gic receptors)
alpha, agonist activity of do-butamine (rats, rabbits, dogs,guinea pigs), 210
aLpha, postsynaptic vascular,
variation in basilar and pal-
monary arteries (rabbits), 83alpha, presynaptic, in spleen
(cat), 162beta quinacrine-blocked desen-
itization after immobilizationstress and isoproterenol(rats), 334
classification into beta-i in-nervated and beta-2 hor-
monal receptors in atria(rats), 395
Airway smooth muscles, compar-ison of effects of ipratropiumbromide and diphemanilmethylsulfate on (guineapigs, cats), 1
Al-Turk, W. A., Stohs, S. J. andRoche, E. B.: Effect of hy-pophysectomy and castration
on hepatic, pulmonary andintestinal aryl hydrocarbonhydroxylase activities in therat, 492
Amethopterin, transport in jeju-num (rats), 329
Amidon, G. L and Buckner, C.K.: On the use of a dynamicapproach to the estimation ofdissociation constants for re-versible competitive antago-nists, 352
a-Aminoisobutyric acid, uptake inplacental villi, effects of cho-line acetyltransferase inhibi-
tom on (man), 232Amphetamine
comparison with tyramine andelectrical stimulation on do-
pamine release from caudatenucleus (rabbits), 592
interaction with drugs inhibit-
ing neurotransmission inspleen (cat), 162
d-Amphetamine, behavioral ef-fects, comparison with nico-tine (monkeys), 484
Amrinone, effects on sodiumtransport and cyclic AMPmetabolism in bladder (toad),220
Anderson, H. T., see Carp, J. S.,270
Angiotensin I, pressor responses,
effect of N-[(S)-1-carboxy-3-phenylpropyl]-L-Ala-L.Pro
and MK-421 on (guinea pigs,rats, dogs), 552
Angiotensin II, role of releasedcatecholamines in vascularresponse to (dog), 104
Antagonists, reversible competi-tive, use ofdynamic approachto estimation of dissociationconstants for (rats), 352
Antihypertensive agent (RO 12-4713), cardiovascular effects
(dogs), 624
Antihypertensive effects, of MK-421 (rats, dogs), 558
Antitumor agent, (acivicin), age-and sex-related toxicity(mice), 433
Antiviral agent, new (5-methoxy-methyl-2’-deoxyuridine), 275
Arbegast, P. T., see Sweet, C. S.,558
Arbilla, S., see Kamal, L A., 592Arrhythmias, ventricular, post-
myocardial infarction re-en-trant, suppression by bretyl-ium tosylate (dogs), 453
Arteries and veins, renal, compar-ison of dependence on cal-cium for responses to norepi-nephrine and potassium
(dogs), 239
Arterybasilar, involvement of adenine
nucleotides in sympatheticnerves of (dogs), 401
basilar and pulmonary, compar-ison of contractile responsesto sympathomimetic agonists(rabbits), 83
femoral, responses to vasodila-tor agents, effect of reserpinepretreatment (dogs), 447
Aryl hydrocarbon hydroxylaseactivity in liver, lung and intes-
tine, effect of hypophysec-tomy and castration (rats),
492of brain, characterization of
(rats, mice, guinea pigs, kites,crows, vultures, pigeons), 156
L-Asparagmase, from Escheria-chin coli, modification withmonomethoxypolyethyleneglycol (rats, mice), 410
Atkinson, A. J., Jr., see Ruo, T. I.,357
Atria, classification of beta-i in-nervated and beta-2 hor-monal adrenoceptors in(rats), 395
Autonomic nervous system (see
Nervous system, autonomic)
Axeirod, J., see Torda, T., 334
Backlund, E. P., see Gross, D. M.,552
Bannon, M. J., see Braszko, J. J.,
289
Barchas, J. D., see Edelman, A.M., 647
Barbieri, E. J., see Khanna, 0. P.,95
Baroreceptor reflex, alteration byan effect of propranolol onisolated carotid sinus (dogs),lii
Bashour, F. A., see Downey, H.F., 372
Beer, B., see Young, W. S. Ill, 434Behavior
discriminative stimulus proper-ties, evaluation of phencyci-dine analogs (rats), 543
effects of fixed ratio and dose
on methohexital-reinforcedresponding (rats), 205
schedule-controlled, effects oflevo-a-acetylmethadol andits metaboites on (pigeons),299
schedule-controlled, effects ofnaltrexone and naloxone on(monkeys, pigeons), 500
schedule-controlled, effects ofnicotine (monkeys), 484
self-administration of cocainederivatives (monkeys), 532
Benowitz, N. L, see Fredericks,
A. B., 247
Benzodiazepine receptors, locali-zation by light microscopicradiohistochemistry (rats),425
Bevan, J. A.: A comparison of thecontractile responses of therabbit basilar and pulmonary
arteries to sympathomimetic
agonists: Further evidence
for variation in vascular ad-renoceptor characteristics, 83
Bigger, J. T., Jr., see Davis, J. C.,39
Bioavailability and pharmacoki-
netics of acyclovir (dogs), 281
Biosynthesis, ofprostaglandins byhydronephrotic kidneys (rab-
bits, cats), 510Bladder
smooth muscle, effects of adre-nergic agonists and antago-mite on (rabbits), 95
urinary, effects of amrinone onsodium transport and cyclicAMP metabolism in (toad),220
Blood flowcerebral, effects of 5-hydroxy-
tryptamine (goats), 599
ischemic myocardial, effects ofsotalol and vagal stimulationon (dogs), 347
renal and splanchnic, duringnicotine infusion, effects ofbeta adrenergic blockade(dogs), 363
renal, effects ofprostaglandin 12and 6-keto-E1 (dogs), 24
Blood pressure, effects of �-9-te-
trahydrocannabinolon (mon-keys), 247
Bloom, F. E., see Schultz, J. E., 28Bloom, F. E., see Wiener, S. G.,
572
656 Index
Blum, M. R, see Krasny, H. C.,
281
Boccagno, J. A., see Voilmer, RR., 225
Bohn, D. L, see Gross, D. M., 552Bovine serum albumin, reversal of
inhibition of opiate receptorbinding by phospholipase A
(rats), 149Boyd, M. R. and Dutcher, J. S.:
Renal toxicity due to reactivemetabolites formed in situ inthe kidney: Investigations
with 4-ipomeanol in themouse, 640
Bradykinin, cardiovascular andsympathetic nerve responses
to (rats), 192
Brain (see also specific part)cerebral cortex, benzodiazepine
receptors (rats), 183characterization of aryl hydro-
carbon hydroxylase of (rats,mice, guinea pigs, kites,crows, vultures, pigeons), 156
decreased catabolism of [3H]-histamine after S-adenosyl-methionine administration(mice), 118
endogenous histamine, role incentral cardiovascular regu-lation (rats), 315
inhibition of opiate receptorbinding by phospholipase Aand reversal by bovine serum
albumin (rats), 149interaction of lisuride with so-
rotonergic and dopaminergicreceptors in (rabbits), 526
localization of benzodiazepinereceptors by light micro-scopic radiohistochemistry in
(rats), 425methionine sulfoximine epilep-
togemc, metabolism of 5-hy-droxytryptamine in (rats), 77
serotonin2 and histamine, re-
captors, Labeling with [3H]-mianserin (rat, guinea pig),142
Tyrosine hydroxylase, phos-
phorylation by cyclic AMP-dependent protein kinase
(cow), 647
Branch, R A., see Jackson, E. K.,24
Branch, R A., see Verbeeck, RK., 479
Braszko, J. J., Bannon, M. J.,Bunney, B. S. and Roth, R.H.: Intrastriatal kainic acid:Acute effects on electrophys-iological and biochemicalmeasures of nigrostriatal do-paminergic activity, 289
Breese, G. R, see Frye, G. D., 306Bretylium tosylate, suppression of
postmyocardial infarction re-entrant ventricular arrhyth-miss by (dogs), 453
Britt, P. M., see Sweet, C. S., 558
Bromberg, J. M., see Speier, S.,101
Bronchodilator agents, parasym-patholytic, ipratropium bro-
mide and diphemanil meth-ylsulfate, comparative study(guinea pigs, cats), 1
Bryan, L. J., Cole, J. J.,O’Donnell, S. R and Wan-stall, J. C.: A study designed
to explore the hypothesis
that beta-i adrenoceptors are“innervated” receptors andbeta-2 adrenoceptors are“hormonal” receptors, 404
Buck, J. D., Warltier, D. C., Hard-man, H. F. and Gross, G. J.:Effects of sotalol and vagalstimulation on ischemic myo-cardial blood flow distribu-tion in the canine heart, 347
Buckner, C. K., see Amidon, G.L, 352
Bu#{241}ag,R D., see Takahashi, H.,
192Bunney, B. S., see Braszko, J. J.,
289
Bush, E. N., see Voilmer, R. R,580
1,3-Butanediol, effects on central
nervous system, comparison
with ethanol (rats), 306Butyryicholinesterases, mono-
meric, from liver, inhibitionby chiorpromazine and otherdrugs (rabbit), 586
Calcium, binding and mobiliza-tion, comparison in renal ar-teries and veins (dogs), 239
Captopril (SQ 14,225), antihyper-tensive activity (dogs), 225
Cardiovascular effects, of Ro 12-4713 (dogs), 624
Cardiovascular regulation, cen-tral, role of histamine in(rats), 315
Cardiovascular responses, tobradykinin (rats), 192
Carp, J. S. and Anderson, R. J.:Modification of spinal cordtransmission by an interac-tion of chiorpromazine andphenytoin, 270
Castration, effect on hepatic, put-monary and intestinal aryl
hydrocarbon hydroxylase ac-tivities (rats), 492
Catabolism, decreased cerebral, of[3H]histamine after S-adeno-sylmethionine administra-
tion (mice), 118Catecholamines (see also specific
names)central, peripheral and gangli-
onic, effects of morphine on(rats), 321
released, role in vascular re.
sponse to angiotensin H(dog), 104
Cations, organic, transport in kid-ney plasma membrane veal-
des (dogs), 294
Cauvin, C. A., Devia, C. J. andKirkendol, P. L: Effect of re-serpine pretreatment on invivo femoral arterial re-
sponses to vasodilator agents,447
Cell R-15, neurosecretory, dopa-mine-sensitive receptor me-diating burst-firing inhibition
of (shellfish), 368Cells, capillary endothelial, sero-
tonin uptake by (rat), 125Cerebellum, effects oflithium and
tricyclic antidepressants onPurkinje cell discharge fre-
quency, norepinephrine re-sponses and beta receptorbinding in (rat), 28
Cerebrovascular effects, of 5-hy-droxytryptamine (goats), 599
Chang, J. K., see Pang, P. K. T.,567
Chapin, H. E., see Frye, G. D., 306
Chaturvedi, A. K., see Sastry, B.
V. R, 387
Chlorothiazide, effects on renal
tubular handling of uric acid(chickens), 441
Chlorpromazineinhibition of monomeric bu-
tyrylcholinesterases (rab-bit), 586
interaction with phenytoin,modification of spinal cordtransmission by (cats), 270
Choline acetyltransferaseinhibitors, effects on a-amino-
isobutyric acid uptake in pie-cental villi (man), 232
inhibitors, inhibition of spermmotility by (man), 378
Cholinergic system, in placental
(man), 232Cicero, T. J., see Owens, D. P.,
135Cimetidine, renal excretion of
(rats), 516Clarkson, T. W., see Dunn, J. D.,
19
Clearance, reduced, of modifiedEacherichia coli L-asparagen-
am (rats, mice), 410Clime, W. J., Jr.: Role of releasd
catecholamines in the vascu-lar response to injected an-giotensin H in the dog, 104
Clomde, effects on tolerance to
ethanol (rats), 459
Cocainederivatives, self-administration
(monkeys), 532
interaction with drugs inhibit-ing neurotransmission inspleen (cat), 162
Cole, J. J., see Bryan, L. J., 404Conjugation, and mixed-function
oxidation, postnatal develop-ment in hemoglobin-free per-fused liver (rats, puppies),473
Contractile responses, of basilarand pulmonary arteries tosympathomimetic agonists
(rabbits), 83Costa, E., see Karoum, F., 321Covalent binding, of[3H]doxorub-
icin (mice), 55
Crystal, G. J., see Downey, H. F.,372
Cyclic 3’ :5’-adenosine monophos-phate, accumulation by al-
Vol. 216
pha-2 adrenergic receptors inisolated islets of Langerhans(rats), 607
Cyclic AMP-dependent proteinkinase, phosphorylation of
tyrosine hydroxylase from
brain by (cow), 647
Das, M., Seth, P. K. and MUkhtar,
H.: Characterization of mi-crosomal aryl hydrocarbon
hydroxylase of rat brain, 156
Daum, A., see Gerold, M., 624
Davis, J. C. and Bigger, J. T., Jr.:The effects ofthioridazine onelectrical and ischemic yen-tricular fibrillation in the dogheart in situ, 39
de Miranda, P., see Krasny, H. C.,281
De Noble, V., see Pickers, H., 205Dependence, physical, on enka-
phalin analogs (rats), 12Dersham, G. H. and Han, J.: Ac-
tions of verapamil on Pur-kinje fibers from normal andinfarcted heart tissues, 261
Desethyl procainamide, metabo-
lite of procainamide, identifi-cation of (mice), 357
Desipramine, effects on discharge
frequency, norepinephrine
responses and beta receptor
binding in cerebellum (rat),28
Devia, C.J., see Cauvin, C. A., 447
Dewey, W. L, see Lamb, H. G.,496
Dexamethasone, effect on matu-ration of sympathetic neuro-transmission in heart (rat), 6
Diamond, L and O’Donnell, M.:
A comparative study of two
parasympatholytic broncho-dilator agents: Ipratropiumbromide and diphemanilmethylsulfate, 1
Dibona, G. F., see Osborn, J. L.,265
Dibutyryl cyclic AMP, effect ofreserpine pretreatment on
femoral arterial responses to(dogs), 447
Dieguez, G., GOmez, B. and Lluch,S.: Analysis of the cerebro-vascular effects of 5-hydroxy-tryptamine in unanesthetized
goats, 599
Diets, D. D., see Sellinger, 0. Z.,77
Diphemanil methylsulfate, corn-parison with ipratropiumbromide (guinea pigs, cats), 1
Dispositionof acivicin (mice), 433of [3H]doxorubicin (mice), 55
of furosemide, liver (dogs), 479of phenol red, effects of narcot-
ice on (mice), 90Dissociation constants, for revere-
ible competitive antagonists,use of dynamic approach to
estimation of (rats), 352Dobutamine
alpha adrenoceptor agonist ac-
1981 lndx 657
tivity of (rats, rabbits, dogs,guinea pigs), 210
Dopaminecell activity, nigrostriatal, ef-
fects of kainic acid on (rats),289
receptors, in brain, interactionwith lisuride (rabbits), 526
release from caudate nucleus,comparison of amphetamine,tyramine and electrical stim-
ulation (rabbits), 592-sensitive receptor mediating
burst-free inhibition of cellR-15 (shellfish), 368
Downey, H. F., Crystal, G. J. andBashour, F. A.: Regionalrenal and splanchnic blood
flows during nicotine infli-
sion: Effects of beta adrener-gic blockade, 372
[�H]Doxorubicin, pharmacoki-netics, covalent binding andsubcellular distribution of(mice), 55
Dubocovich, M. L, see Langer, S.z., 162
Dunn, J. D., Clarkson, T. W. andMagos, L: Interaction ofethanol and inorganic mer-cury: Generation of mercuryvapor in vivo, 19
Durant, N. see Lambert, J. J.,62
Dutcher, J. S., see Boyd, M. R,
640
Edelman, A. M., Reese, J. D., La-
zar, M. A. and Barchas, J. D.:Tyrosine hydroxylase: Stud-ies on the phosphorylation ofapurified preparation of thebrain enzyme by the cyclicAMP-dependent protein Id-
nase, 647
Eigenmann, R, see Gerold, M.,624
Elion, G. B., see Krasny, H. C.,281
Endotoxin-induced pyrexia, influ-ence on pharameokinetics ofgentamicin (rabbits), 415
End-plate conductance, in fran-
sected muscle, modification
by drugs (frog), 62Enkaphalin analogs, ability to
produce physical dependence
(rats), 12Enzyme
angiotensin converting, effectof N-[(S)-1-carboxy-3-phen-ylpropyl]-L-Ala-L-Pro andMK-421 on (guinea pigs, rats,
dogs), 552angiotensin converting, inhibi-
tion by captopril (dogs), 225angiotensin converting, inhibi-
tion by MK-421 (rats, dogs),558
Enzymes, hepatic drug metaboliz-ing, retrograde perfusion toprobe distribution of (rats),339
Eriaii, R, see Plante, G. E., 617Ethacrynic acid, effects on renal
tubular handling of uric acid(chickens), 441
Ethanolactivation of adenylate cyclase
in striata.l tissue by (mice),129
effects on central nervous sys-tern, comparison with 1,3-bu-tanediol (rats), 306
interaction with nutrition dur-lag gestation, influence onmaternal and offspring devel-opment (rats), 572
maternal consumption, inhibi-tion of placental valine up-
take after (rats), 465role in mercury exhalation
(mice), 19tolerance to, interactions with
pimozide and clonidine (rats),459
Excretionrenal, of cimetidine (rats), 516renal, oflevamisole (dogs), 617
Faulkner, G. D, see Rush, R S.,586
Ferko, A. P., see Mullin, M. J., 459Fibrillmion, ventricular, effect of
thioridazine on (dogs), 39[3H]Flunitrazepan, use in identi-
fication ofbenzodiazepine re-ceptors in cerebral cortex
(rats), 183Fredericks, A. B., Benowitz, N. L
and Savanapndi, C. Y.: Thecardiovascular and auto-nomic effects of repeated ad-ministration of �-9-tetrahy-drocannabinol to rhesusmonkeys, 247
Frye, G. D., Chapin, H. E., Vogel,H. A., Mailman, H. B., Kilts,C. D., Mueller, H. A. andBreese, G. R: Effects of acute
and chronic 1,3-butanedioltreatment on central nervoussystem function A compari-
son with ethanol, 306Fujiwara, M., see Muramatsu, I.,
410Furosemide
disposition in liver (dogs), 479effects on renal tubular han-
dling of uric acid (chickens),441
oxotoxicity of (chinchilla), 537
GalaCtOse, uptake into centrilob-tiler and periportal enriched
hepatocytes (rats), 634
Gardner, M. L, see Spealman, RD., 484
Gaul, S. L, see Sweet, C. S., 558Gentainicin, pharmacokinetics,
influence of endotoxin-in-duced pyrexia on (rabbits),415
Gerkens, J. F., see Jackson, E. K.,24
Gerkens, J. F., see Verbeeck, R.K., 479
Gerold, M., Eigenmann, R, Hefti,F., Daum, A. and Haeusler,G.: Cardiovascular effects of
a novel vasoactive antihyper-tensive agent, Ho 12-4713,
624Gertner, S. B., see Klein, M. C.,
315Gestation, interaction of ethanol
and nutrition during (rats),572
Gibson, J. K., see Patterson, E.,453
Girl, S. N., see Marafino, B. J., Jr.,55
Glands, submaxillary, changes inbeta adrenergic receptors
after reserpine or isoprotere-
not (rats), 419Goldberg, D. M., see Goldberg, S.
R,500
Goldberg, S. R, Morse, W. H. andGoldberg, D. M.: Acute andchronic effects of naltrexoneand naloxone on schedule-
controlled behavior of squir-rel monkeys and pigeons, 500
Goldberg, S. R, see Spealman, R
D., 484G#{243}mez, B., see Dieguez, 0., 599Gospe, S. M., Jr. and Wilson, W.
A., Jr.: Pharmacological stud-ies of a novel dopamine-sen-sitive receptor mediatingburst-firing inhibition of neu-rosecretory cell R-15 in Aply-ski californica, 377
Green, T. P., Rybak, L P., Mirkin,
B. L, Juliri, S. K. and Mori-
zono, T.: Pharmacologic de-terminants of ototoxicity offurosemide in the chinchilla,
537Gross, D. M., see Sweet, C. S., 558Gross, D. M., Sweet, C. S., Uhn,
E. H., Backlund, E. P., Mor-na, A. A., Weitz, D., Balm, D.
L, Wenger, H. C., Vassil, T.C. and Stone, C. A.: Effect ofN-[(S)-1-carboxy-3-phenyl-
propyl]-L-Ala-i.-Pro and itsethyl ester (MK-421) on an-giotensin converting enzyme
in vitro and angiotensin Ipressor responses in vivo, 552
Gross, F., see Khayyal, M, 399Gross, G. J., see Buck, J. D., 347Gupta, V. S., see Meldrum, J. B.,
275
Haeusler, G., see Gerold, M., 624
Halldn, H., Lidji, M. and Rubin-stein, E.: The influence ofendotoxin-induced pyrexiaon the pharmacokinetics ofgentan#{252}cin in the rabbit, 424
Han, J., see Dersham, G. H., 261Harden, T. K., see McCarthy, K.
D., 183Hardman, H. F., see Buck, J. D.,
347Heart
effects ofsotaloland vagal stim-ulation on ischemic myocar-dial blood flow in (dogs), 347
maturation ofsympathetic neu-retransmission in (rat), 6
mechanical performance and
electrical activity, effects ofadenosine (dogs), 254
muscle, effects of quinidine on(guinea pigs, cats), 176
postmyocardial infarction re-entrant ventricular arrhyth-miss, suppression by bretyl-ium tosylate (dogs), 453
ventricular fibrillation, effects
of thioridazine (dogs), 39Heart rate, effects of A-9-tetra-
hydrocannabinol on (mon-keys), 247
Heart tissues, normal and in-farcted, actions of verapamilon Purkinje fibers from(dogs), 261
Hechtman, H. B., see Robinson-
White, A., 125Hefti, F., see Gerold, M., 624Henderson, E. G., see Lambert, J.
J_, 62Henderson, G. I., Turner, D., Pa-
twardhan, R V., Lumeng, L,Hoyumpa, A. M. andSchenker, S.: Inhibition ofplacental valine uptake after
acute and chronic maternalethanol consumption, 465
Henthorn, T., see Ruo, T. I., 357Hepatocytes, centrilobuler and
periportal enriched, uptakeofgalactose, ouabain and tau-rocholate into (rats), 634
Heroin, self-administration, ef-fects of naltrexone (man), 45
Hen, A., see Schulz, R., 604
Herser, W. A., see Jackson, E. K.,24
Hester, R K. and Weiss, G. B.:Comparison of degree of de-pendence of canine renal ax-
teries and veins on high andlow affinity calcium for re-ponses to norepinephrine andpotassium, 239
Hirata, F., see Torda, T., 334Histamine, endogenous, role in
central cardiovascular regu-lation (rats), 315
[�H]Histamine, decreased core-bra! catabolism after S-ad-enosylmethionine adminis-
tration (mice), 118Histamine-N-methyltransferase,
inhibition by SKF 91488
(rats), 315Ho, I. K., see Nabeshima, T., 198Holland, M.-J. C., see Lin, H-K.,
149Holmberg, S., see Reingold, D. F.,
510
Holohan, P. D. and Roes, C. R:Mechanisms of organic cat-ion transport in kidneyplasma membrane vesicles: 2.�pH studies, 294
Honegger, U. E., see Reacher, A.A., 428
Horovitz, Z. P., see Voilmer, R.R., 225
HUYW1tZ, A.: Narcotic effects onphenol red disposition in
mice, 90Hoyumpa, A. M., see Henderson,
658 Index
G. I., 465Hydralazine
effect ofreserpine pretreatmenton femoral arterial responsesto (dogs), 447
in isolated renal artery, vasodi-lator effect of (rabbit), 390
Hydromorphine, effect on phenolred disposition (mice), 90
5-(p-Hydroxyphenyl)-5-phenyl-
hydantoin, interaction with
phenytoin and valproate(rats), 613
5-Hydroxytryptamine (see alsoserotonin)
cerebrovascular effects of(goats), 599
metabolism in methionine sal-foximine epileptogenic brain(rats), 77
Hyperlactatemia, effects of so-dium 2-chloropropionate on(dogs), 172
Hypertension, two-kidney model,
antihypertensive effect ofcaptopril (dogs), 225
Hypophysectomy, effect on he-patic, pulmonary and intes-
tinal aryl hydrocarbon hy-droxylase activities (rats),492
Hypotension, induced by sodium
nitroprusside, effects of die-tary sodium on role of reninangiotensin system duringand after (rats), 580
Hypotensive action, of syntheticfragments of parathyroidhormone (dogs, rats), 567
Hypothalamic-pituitary-luteiniz-
ing hormone axis, toleranceto effects of naloxone on(rat), 135
Imipramine, effects on discharge
frequency, norepinephrineresponses and beta receptorbinding in cerebellum (rat),28
Immunogenicity, reduced, ofmodified Escherichia coil L-
asparaginase (rats, mice), 410made, Y., see Kamisaki, Y., 419Infarction, myocardial, re-entrant
ventricular arrhythmiasafter, suppression by bretyl-
ium tosylate (dog), 453Insulin, release by aipha-2 adre-
nergic receptors in isOlated is-lets of Langenhans (rats), 607
Intestineeffect of hypophysectomy and
castration on aryl hydrocar-
hon hydroxylase activity in(rats), 492
small, HgCl2 inhibition of nutri-
ent transport in (fish), 70transit, interactions of reserpine
and morphine on (rats), 5214-Ipomeanol, metabolites, renal
toxicity by (mice), 640Ipratropium bromide, comparison
with diphemanil methylsul-fate (guinea pigs, cats), 1
Ishii, K., see Nakaki, T., 607
Islets of Langerhans, isolated, in-
sulin release and cyclic 3’:5’-adenosine monophosphateaccumulation by alpha-2 ad-renergic receptors in (rats),
607
Isoproterenolchanges in beta adrenergic re-
ceptors in submaxillaryglands after (rats), 419
effect of reserpine pretreatmenton femoral arterial responsesto (dogs), 447
quinacrine-blocked desensitiza-
tion of beta adenoceptorsafter (rats), 334
Jackson, E. K., Herzer, W. A.,Zimmerman, J. B., Branch,R A., Oaths, J. A. and Ger-kens, J. F.: 6-Keto-prosta-glandin E, is more potentthan prostaglandin 12 as arenal vasodilator and reninsecretagogue, 24
Jacoby, M., see Levine, S. D., 220James, T. N., see Urthaler, F., 254
Janson, V. E., see Sastry, B. V. R,387
Jejunum, transport of pteroylglu-
tamate and amethopterin in(rats), 329
Juhn, S. K., see Green, T. P., 537
Kainic acid, intrastriatal, effectson nigrostriatal dopaminecell activity (rats), 289
Kamal, L A., Arbilla, S. and Lan-ger, S. Z.: Presynaptic modu-lation of the release of dopa-mine from the rabbit caudatenucleus: Differences betweenelectrical stimulation, am-phetamine and tyramine, 592
Kamisaki, Y., Wads, H., Yagura,T., Mataushima, A. and In-
ada, Y.: Reduction in immu-nogenicity and clearance rateof Escherichia coli L-aspara-
ginase by modification withmonomethoxypolyethyleneglycol, 419
Karoum, F., Wyatt, R J. andCosta, E.: A comparativestudy on the effects of mor-
phine on central, peripheral
and gangliomc stores of cat-echolamines, 321
Kato, H., see Nakaki, T., 607
Kelleher, R. T., see Spealinan, R.
D., 532Kenakin, T. P.: An in vitro quan-
titative analysis of the alphaadrenoceptor partial agonist
activity of dobutamine andits relevance to inotropic so-
lectivity, 210Khanna, 0. P., Barbieri, E. J. and
McMichael, R F.: The effectsof adrenergic agonists andantagonists on vesicourethralsmooth muscle of rabbits, 95
Khayyal, M., Gross, F. and Kreye,V. A. W.: Studies on the di-rect vasodilator effect of hy-dralazine in the isOlated rab-bit renal artery, 399
Kidney
arteries and veins, dependenceon calcium for responses tonorepinephrine and potas-sium (dogs), 239
beta-i receptor mediation of reamsecretion from (dogs), 265
blood flow during nicotine in-fusion, effects of beta adre-nergic blockade (dogs), 363
effects of 4-ipomeanol meta-bolic activation (mice), 640
excretion of cimetidine (rats),516
excretion of levamisole (dogs),617
hydronephrotic, biosynthesis of
prostaglandins by (rabbits,cats), 510
involvement of prostaglandin 12
and 6-keto-E3 on ream secre-tion from (dogs), 24
isolated artery, vasodilator ef-fect of hydralazine in (rab-bit), 390
plasma membrane vesicles, or-ganic cation transport in(dogs), 294
tubular handling of uric acid,effects of furosemide, etha-crynic acid and chiorothia-ride (chickens), 441
Kilpatrick, B. F., see Rush, R. S.,586
Kilts, C. D., see Frye, G. D., 306Kinetics (see also Pharmacoki-
netics)of end-plate conductance, in
transected muscle, modifica-
tion by drugs (frog), 62Kirkendol, P. L, see Cauvin, C.
A., 447
Klaassen, C. D., see Stacey, N. H.,634
Klein, M. C. and Gertner. S. B.:Evidence for a role of endog-enous histamine in centralcardiovascular regulation: In-
hibition of histamine-N-methyltransferase by SKF 91
488, 315Koda, L. Y., see Wiener, S. G., 572Kopin, I. J., see Torda, T., 334Krasny, H. C., de Miranda, P.,
Blum, M. R. and Elion, G. B.:Pharmacokinetics and bioa-vailabiity of acyclovir in thedog, 281
Kreye, V. A. W., see Khayyal, M.,399
Kuehnle, J. C., see Mello, N. K.,45
Kuhar, M. J., see Young, W. S.ifi, 434
Lamb, R G. and Dewey, W. L:Effect of morphine exposureon mouse liver triglycerideformation, 496
Lambert, J. J., Durant, N. N.,Reynolds, L S., Voile, R Land Henderson, E. G.: Char-acterization of end-plate con-ductance in transected frogmuscle: Modification bydrugs, 62
Vol. 216
Langer, S. Z. and Dubocovich, M.L: Cocaine and amphet-amine antagonize the de-crease of noradrenergic neu-rotransmission elicited by ox-ymetazoline but potentiatethe inhibition by a-methyl-norepinephrine in the per-fused cat spleen, 162
Langer, S. Z., see Kamal, L A.,
592
Lau, C. and Slotkin, T. A.: Matu-ration of sympathetic neuro-transmission in the rat heart.VII. Suppression of sympa-thetic responses by dexa-methasone, 6
Laubscher, A., Pletscher, A. andNoil, H.: Interaction of D-
LSD with blood platelets ofrabbits: Shape change andspecific binding, 394
Lazar, M. A., see Edelman, A. M.,647
Lempert, N., see Speier, S., 101Levamisole, renal excretion of
(dogs), 617
Levine, S. D., Jacoby, M., Satri-ano, J. A. and &hlondorff,D.: The effects of amrinoneon transport and cyclic AMPmetabolism in toad urinarybladder, 220
Lidji, M., see Halkin, H., 424Light microscopic radiohisto-
chemistry, localization ofbenzodiazepine receptors by(rats), 425
IAn, H.-K., Holland, M.-J. C. andSimon, E. J.: Characteriza-tion of phospholipase A inhi-bition ofstereospecific opiatebinding and its reversal bybovine serum albumin, 149
Lippa, A. S., see Young, W. S. III,434
Lisuride, interaction with seroto-nergic and dopaminergic re-ceptors in brain (rabbits), 526
Lithium, effects on discharge fre-quency, norepinephrine re-sponse and beta receptorbinding in cerebellum (rat),28
Liverdisposition of furosemide in
(dogs), 479drug metabolizing enyzmes, ret-
rograde perfusion to probedistribution (rats), 339
effect of hypophysectomy andcastration on aryl hydrocar-boa hydroxylase activity in(rats), 492
inhibition by chlorpromazine ofmonomeric butyrylcholines-terases from (rabbit), 586
perfused, hemoglobin-free,postnatal development ofmixed-function oxidation andconjugation in (rats, pup-pies), 473
triglyceride formation, effect of
morphine exposure (mice),
496Lluch, S., see Dieguez, G., 599
1981 Index 659
Loubatieres-Mariani, M. M., seeRibes, G., 172
D-LSD, interaction with bloodplatelets (rabbits), 385
Lucchesi, B. R., see Patterson, E.,453
Ludden, C. T., see Sweet, C. S.,558
Lumeng, L., see Henderson, G. I.,465
Lung, effect of hypophysectomyand castration on aryl hydro-
carbon hydroxylase activityin (rats), 492
Magos, L., see Dunn, J. D., 19Mailman, R. B., see Frye, G. D.,
306Main, A. R, see Rush, R S., 586Makman, M. H., see Rosenfeld,
M. R., 526Marafino, B. J., Jr., Gin, S. N. and
Siegel, D. M.: Pharmacoki-netics, covalent binding andsubcellular distribution of[3H]doxorubicin after intra-venous administration in themouse, 55
Matsushima, A., see Kamisaki, Y.,419
McCarthy, K. D. and Harden, T.K.: Identification of two ben-zodiazepine binding sites oncells cultured from rat cere-bral cortex, 183
McGivney, W. T. and McMillan,D. E.: The effects of ievo-a-acetylmethadol and its me-tabolites on schedule-con-trolled behavior in the pi-geon, 299
McGovren, J. P., Neil, G. L, Sem,P. C. C. and Stewart, J. C.:Sex- and age-related mousetoxicity and disposition of theamino acid antitumor agent,acivicin, 433
McMichael, R. F., see Khanna, 0.P., 95
McMillan, D. E, see McGivney,
W. T., 299Mercury, exhalation, role of
ethanol (mice), 19Mercury chloride, inhibition of
nutrient transport in small
intestine (fish), 70Meldrum, J. B., Gupta, V. S., Ta-
neja, A. K. and Sisodia, C. S.:Pharmacological studies on5-methoxymethyl-2’-deoxy-uridine: A new antiviral
agent, 275Mello, N. K., Mendelson, J. H.,
Kuehnle, J. C. and Sellers, M.
S.: Operant analysis of hu-man heroin self-administra-tion and the effects of nut-trexone, 45
Mendelson, J. H., see Mello, N.K., 45
Metabolism
cyclic AMP, in bladder, effectsof amrinone (toad), 220
of 5-hydroxytryptamine in me-thionine sulfoximine epilep-togenic brain (rats), 77
Methadone, effect on phenol red
disposition (mice), 90
Methionine sulfoximine, effectson metabolism of 5-hydroxy-tryptamine in brain (rats), 77
Methohexital-reinforced re-sponding, effects of fixed ra-tio and dose (rats), 205
5-Methoxymethyl-2’-deoxyuri-dine, pharmacological studies
(mice, rats, rabbits), 275a-Methylnorepinephrine-in-
hibited neurotransmission in
spleen, effect of cocaine andamphetamine (cat), 162
Methylprednisolone sodium suc-ciiiate and phenytoin, effectson skin graft survival (mice),101
[3H}Mianserin, labeling of sero-tonin2 and histamine, recep-tore in brain (rat, guinea pig),142
Miller, D. S.: HgC1� inhibition ofnutrient transport in teleostfish small intestine, 70
Mirkin, B. L, see Green, T. P.,537
Miura, A., see Muramatsu, I., 410MK-421
antihypertensive activity of
(rats, dogs), 558effecton angiotensin converting
enzyme and angiotensin Ipresser responses (guinea
pigs, rats, dogs), 552Molinoff, P. B., see Rabin, R A.,
129
Monomethoxypolyethylene gly-col, modification of Esche-richia coil L-asparaginase
(rats, mice), 410Morita, Y., see Ruo, T. I., 357
Morizono, T., see Green, T. P.,537
Morphineeffects on central, peripheral
and ganglionic catechol-amines (rats), 321
effect on phenol red disposition(mice), 90
exposure, effect on liver triglyc-eride formation (mice), 496
interactions with reserpine onintestinal transit (rats), 521
Morris, A. A., see Gross, D. M.,552
Morse, W. H., see Goldberg, S. R,500
Motility index, ofsperm, effects ofinhibitors of choline acetyl-transferase (man), 378
Muchow, D., see Pickens, R., 205Mueller, R. A., see Frye, G. D.,
306Mukhtar, H., see Das, M., 156Mullin, M. J. and Ferko, A. P.:
Ethanol and functional to!.erance: Interactions with pi-mozide and clonidine, 459
Muramatsu, I., Fujiwara, M.,Miura, A. and Sakakibara, Y:Possible involvement of ade-nine nucleotides in sympa-
thetic neuroeffector mecha-nisms of dog basilar artery,
410Murthy, V. S., see Voilmer, R. R,
225Muscle
smooth, vesicourethral, effects
of adrenergic agonists andantagonists on (rabbits), 95
transected, end-plate conduct-ance, modification by drugs(frog), 62
Nabeshima, T. and Ho, I. K.:Pharmacological responses
to pentobarbital in different
strains of mice, 198Nakadate, T, see Nakaki, T., 607
Nakaki, T, Nakadate, T., Ishui, K.and Kato, R.: Postsynapticaipha-2 adrenergic receptors
in isolated rat islets of Lan-gerhans: Inhibition of insulinrelease and cyclic 3’:S’-aden-osine monophosphate accu-mutation, 607
Naloxoneeffects on hypothalamic-pitu-
itary-luteinizing hormoneaxis, tolerance to (rat), 135
effect on phenol red disposition(mice), 90
effects on schedule-controlledbehavior (monkeys, pigeons),500
Naltrexoneeffects on heroin seif-adminis-
tration (man), 45effects on schedule-controlled
behavior (monkeys, pigeons),500
Narcotics (see specific drug)
Nawrath, H.: Action potential,membrane currents and forceof contraction in mammalian
heart muscle fibers treatedwith quinidine, 176
Needleman, P., see Reingold, D.
F., 510Neil, G. L, see McGovren, J. P.,
433Nerve
sympathetic, of basilar artery,
involvement of adenine nu-cleotides (dogs), 401
sympathetic, responses tobradykinin (rats), 192
Nerve stimulation, renal, beta-i
receptor mediation of renin
secretion elicited by (dogs),
265
Nervous systemautonomic, effects of i�-9-te-
trahydrocannabinol on (mon.keys), 247
central, comparison of effects of1,3-butanediol and ethanol
(rats), 306central, interactions of chior-
promazine and phenytoin(cats), 270
sympathetic, maturation (rat),6
Neurotransmissionnoradrenergic, inhibited by
drugs, effects of cocaine andamphetamine (cat), 162
sympathetic, maturation in
heart (rat), 6Nicotine
effects on schedule-controlledbehavior (monkeys), 484
infusion, effects on renal andsplanchnic blood flows withand without beta adrenergic
blockade (dogs), 363Niehoff, D., see Young, W. S. IH,
434Nigrostriatal dopamine cell activ-
ity, effects of intrastriatalkainic acid on (rats), 289
Nitroglycerin, effect of reserpinepretreatment on femoral ax-
terial responses to (dogs), 447
Noll, H., see Laubscher, A., 394Norepinephrine
responses, in cerebellum, effectof lithium and tricyclic anti-depressants (rat), 28
responses, of renal arteries andveins, dependence on calcium(dogs), 239
N[(S)-1-carboxy-3-phenylpropyl]-L-Ala-L-Pro, effect on anglo-tensin converting enzyme
and angiotensin I presser re-spouses (guinea pigs, rats,dogs), 552
Nutrient, absorption in small in-testine, inhibition by HgCl2(fish), 70
Nutrition, interaction with eth-
anol during gestation, influ-ence on maternal and off-spring development (rats),572
Oates, J. A., see Jackson, E. K., 24O’Donnell, M., see Diamond, L,
O’Donnell, S. R., see Bryan, L J.,404
O’Leary, T. D. and Sansom, L N.:Interaction between pheny-
toin, 5-(p-hydroxyphenyl)-5-phenyihydantoin and val-proate in the rat, 613
Osborn, J. L, Dibona, G. F. andThames, M. D.: Beta-i recep-tor mediation of ream secre-tion elicited by low-frequencyrenal nerve stimulation, 265
Ouabain, uptake into centrilobu-
lar and periportal enrichedhepatocytes (rats), 634
Owens, D. P. and Cicero, T. J.:Development of acute toter-ance to the effects of nalox-one on the hypothalamic-pi-tuitary-luteinizing hormoneaxis in the male rat, 135
Oxidation, mixed-function andconjugation, postnatal devel-opment in hemoglobin-freeperfused liver (rats, puppies),473
Oxotoxicity, of furosemide (chin-
cilia), 537
Oxymetazoline-inhibited neuro-transmission in spleen, effectof cocaine and amphetamine(cat), 162
Pang, K. S. and Terrell, J. A.:
660 Index
Retrograde perfusion toprobe the heterogeneous cbs-tribution of hepatic drug me-
tabolizing enzymes in rats,339
Pang, P. K. T., Yang, M. C. M.,Tenner, T. E., Jr., Chang, J.K. and Shimizu, M.: Hype-tensive action of syntheticfragments of parathyroidhormone, 567
Parathyroid hormone, synthetic
fragments, hypotensive ac-tions of (dogs, rats), 567
Patterson, E., Gibson, J. K. andLucchesi, B. R: Postmyocar-dial infarction re-entrantventricular arrhythmias inconscious dogs: Suppression
by bretylium tosylate, 453Patwardhan, R. V., see Hender-
son, G. I., 465Pentobarbital, pharmacological
responses in different strains
(mice), 198
Peroutka, S. J. and Snyder, S. H.:(3H]Mianserin: Differentiallabeling ofserotonin2 and his-tamine1 receptors in ratbrain, 142
Peterson, S., see Robinson-White,
A., 125
Petitclerc, C., see Plante, G. E.,617
Pharmacokinetics (see also Xi-netics)
and bioavailability of acyclovir(dogs), 281
of acivicin (mice), 433of [‘Hjdoxonibicin (mice), 55
of gentamicin, influence ofendotoxin-induced pyrexiaon (rabbits), 415
of 5-methoxymethyl-2’-deoxy-uridine (mice, rats, rabbits),275
of phenacetin and acetamino-phen, studied by retrogradeperfusion (rats), 339
Pharmacological responses, topentobarbital in different
strains (mice), 198
Phencycidine analogs, discrimi-native stimulus properties(rats), 543
Phenol red, disposition, effects ofnarcotics on (mice), 90
Phenothiazine, inhibition of mon-omeric butyrylcholinester-ases (rabbit), 586
Phenytoinand methylprednisolone so-
dium succinate, effects on
skin graft survival (mice), 101interaction with chlorproma-
zine, modification of spinalcord transmission by (cats),
270interaction with 5-(p-hydroxy.
phenyl)-5-phenylhydantoin
and valproate (rats), 613Phospholipase A, inhibition of
opiate receptor binding by(rats), 149
Phosphorylation, of tyrosine hy-
droxylase from brain by
cyclic AMP-dependent pro-tein kinase (cow), 647
Pickens, R, Muchow, D. andDeNoble, V.: Methohexital-reinforced responding in rats:Effects of fixed ratio size andinjection dose, 205
Pimozide, effects on tolerance to
ethanol (rats), 459Placental
isolated, cholinergic system in(man), 232
valine uptake, inhibition aftermaternal ethanol consump-
tion (rats), 465Plante, G. E., Erian, R and Petit-
clerc, C.: Renal excretion oflevamisole, 617
Plasma, membrane vesicles, kid-
ney, organic cation transport
in (dogs), 294Platelets, blood, interaction with
D-LSD (rabbits), 385Pletscher, A., see Laubscher, A.,
394Potassium, responses, of renal ax-
teries and veins, dependenceon calcium (dogs), 239
Procainamide, new metabolite(desethyl procainamide)(mice), 357
Propranolol, effects on isolated
carotid sinus (dogs), liiProstaglandin
byosynthesis by hydro-ne-
phrotic kidneys (rabbits,cats), 510
6-keto-E, and 12, effect on reninsecretion in kidney (dogs), 24
Pteroylglutamate, transport in je-junum (rats), 329
Purkinje fibers, from normal andinfarcted heart tissues, ac-tions of verapamil on (dogs),
261Pyrexia, endotoxin-induced, influ-
ence on pharmacokinetics ofgentamicin (rabbits), 415
Quebbemann,, A. J., see Shide-man,J.R.,441
Quinacrine-blocked desensitize-
tion of beta adrenoceptorsafter immobilization stress orisoproterenol (rats), 334
Quinidine, effects on heart muscle
(guinea pigs, cats), 176
Rabin, R A. and Molinoff, P. B.:Activation of adenylate cy-clam by ethanol in mousestriate! tissue, 129
Reese, J. D., see Edelman, A. M.,647
Receptorsbenzodiazepine, in cerebral cor-
tex (rats), 183benzodiazepine, localization by
light microscopic radiohisto-
chemistry (rats), 425beta-i, mediation of renin so-
cretion elicited by renal nervestimulation (dogs), 265
binding, beta, in cerebellum, ef-
fects of lithium and tricycic
antidepressanth (rat), 28dopamine, presynaptic in cau-
date nucleus (rabbits), 592dopamine-sensitive, mediating
burst-firing inhibition of cellR-15 (shellfish), 368
opiate, binding, inhibition byphosphoipase A and reversalby bovine serum albumin
(rats), 149serotonergic and dopaminergic,
in brain, interaction of lisur-ide with (rabbits), 526
serotonin2 and histamine, inbrain, labeling with [3H]-mianserin (rat, guinea pig),142
Reingold, D. F., Watters, K.,Holmberg, S. and Needle-
man, P.: Differential biosyn-thesis of prostaglandins byhydronephrotic rabbit andcat kidneys, 510
Reinke, L. A., see Sonawane, B.R., 473
Renin angiotensin system, roleduring and after sodium am-troprusside-induced hype-
tensin, effect of dietary so-dium on (rats), 580
Renmsecretion elicited by renal nerve
stimulation, beta-i receptormediation (dogs), 265
secretion from kidney, involve-ment of prostaglandin 12 and6-keto-E1 (dogs), 24
Reserpinechanges in beta adrenergic re-
ceptors in submaxillary
glands after (rats), 419interactions with morphine on
intestinal transit (rats), 521pretreatment, effect on femoral
arterial responses to vasodi-
lator agents (dogs), 447
Retrograde perfusion, to probedistribution of hepatic drugmetabolizing enzymes (rats),
339Reynolds, L S., see Lambert, J.
J.,62Ribes, G., Valette, G., Valette, J.
F. and Loubatieres-Mariani,M. M.: Sodium 2-chloropro-pionate: Its effects on exper-imental hyperlactatemia inthe dog, 172
Ho 12-4713, cardiovascular effects(dogs), 624
Robinson-White, A., Peterson, S.,Hechtman, H. B. and Shepro,D.: Serotonin uptake by iso-lated adipose capillary endo-
thelium, 125
Roche, E. B., see Al-Turk, W. A.,492
Reacher, A. A., Wiesmann, U. N.
and Honegger, U. E.:Changes in beta adrenergicreceptors in submaxillaryglands of chronically reser-pine- or isoproterenol-treatedrats, 428
Vol. 216
Rosenfeld, M. R and Makman,M. H.: The interaction of is-uride, an ergot derivative,with serotonergic and dope-minergic receptors in rabbitbrain, 526
Ross, C. R, see Holohan, P. D.,294
Roth, L., see Weiner, I. M., 516Roth, R H., see Braszko, J. J., 289Rowell, P. P. and Sastry, B. V. R.:
Human placental cholinergicsystem: Depression ofthe up-
take of a-aminoisobutyricacid in isolated human pta-cental villi by choline acetyl-transferase inhibitors, 232
Rubinstein, E., see Halide, H., 424Ruo, T. I., Morita, Y., Atkinson,
A. J., Jr., Henthorn, T. andThenot, J.-P.: Identificationof desethyl procainamide inpatients: A new metabolite ofprocainamide, 357
Rush, R. S., Main, A. R, Kilpa-trick, B. F. and Faulkner, G.D.: Inhibition of two mono-
meric butyrylcholinesterasesfrom rabbit liver by chiorpro-maxine and other drugs, 586
Rybak, L see Green, T. P., 537
Sakakibara, Y., see Muramatsu,
I.,410Sansom, L N., see O’Leary, T. D.,
613Sastry, B. V. It, Janson, V. E. and
ChaturVedi, A. K.: Inhibitionof human sperm motility byinhibitors of choline acetyl-transferase, 387
Sastry, B. V. R, see Howell, P. P.,232
Satriano, J. A., see Levine, S. D.,220
Savanapridi, C. Y., see Fredericks,A. B., 247
Schatz, H. A., Stramentinoli, G.
and Sellinger, 0. Z.: De-creased cerebral catabolism
of[’Hjhistamine in vivo after
S-adenosylmethionine ad-ministration, 118
Schenker, S., see Henderson, G.I., 465
Schiondorif, see Levine, S. D.,220
Sehocker, F. W., see Schultz, J.E., 28
Schults, H. D. and Zehr, J. E.:Alteration of the barorecep-tor reflex by an effect of pro-pranolol on the isolated ca-rotid sinus, lii
Schultz, J. E., Siggins, G. R,Schocker, F. W., Tilrck, M.and Bloom, F. E.: Effects ofprolonged treatment withlithium and tricycic antide-pressants on discharge fre-quency, norepinephrine re-sponses and beta receptorbinding in rat cerebellum:Electrophysiological and bio-chemical comparison, 28
1981 Index 661
Schulz, R, W#{252}ster, M. and Hen,A.: Pharmacological charac-
terization of the s-opiate re-ceptor, 604
Sellers, M. see Mello, N. K., 45Sellinger, 0. Z. and Diets, D. D.:
The metabolism of 5-hy-droxytryptamine in the me-thionine sulfoximine epilep-togemc rat brain, 77
Sellinger, 0. Z., see SChatZ, R A.,118
Sem, P. C. C., see McGovren, J.P., 433
Serotoninreceptors, in brain, interaction
with lisuride (rabbits), 526uptake by isolated adipose cap-
illary endothelium (rat), 125
Seth, P. K., see Das, M., 156
Shannon, H. E.: Evaluation ofphencycidine analogs on thebasis of their discriminativestimulus properties in the rat,543
Shepro, D., see Robinson-White,
A., 125Shideman, J. R, Zmuda, M. J.
and Quebbemann, A. J.: Theacute effects of furosemide,ethacryrnc acid and chloro-thiazid#{235} on the renal tubularhandling of uric acid in thechicken, 441
Shimizu, M., see Pang, P. K. T.,567
Shoemaker, W. J., see Wiener, S.G., 572
Siegel, D. M., see Marafino, B. J.,Jr., 55
Siggins, G. R., see Schultz, J. F.,28
Simon, E. J., see Lin, H.-K., 149Sinus, isOlated carotid, effects of
propranolol (dogs), liiSisodia, C. S., see Meldrum, J. B.,
275SKF 91488, inhibition of hista-
mine-N-methyltransferase(rats), 315
Skin graft survival, effects ofphenytoin and methylpred-nisolone sodium succinate
(mice), 101Slotkin, T. A., see Lau, C., 6Snyder, S. H. see Peroutka, S. J.,
142Sodium
dietary, effect on renin angie-tensin system during andafter sodium nitroprusside-
induced hypotensin (rats),580
transport in bladder, effects ofamrinone (toad), 220
Sodium 2-chloropropionate, ef-fects on hyperlactatemia(dogs), i72
Sodium nitroprusside-inducedhypotensin, effect of dietary
sodium on role ofrenin anglo-tensin system during andafter (rats), 580
Sonawane, B. R, Yaffe, S. J.,Reinke, L A. and Thurman,
a G.: Postnatal developmentof mixed-function oxidationand conjugation in hemoglo-bin-free perfused rat liver,473
Sotalol, effects on ischemic myo-cardial blood flow (dogs), 347
Spealman, R D. and Kelleher, RT.: Self-administration of co-caine derivatives by squirrel
monkeys, 532Spealman, R. D., Goldberg, S. R
and Gardner, M. L: Be-havioral effects of nicotine:Schedule-controlled re-
spending by squirrel mon-keys, 484
Speier, S., Bromberg, J. M. andLempert, N.: Phenytoin,methylprednisolone sodiumsuccinate and graft survival,101
Sperm motility, inhibition by in-hibitors of choline acetyl-transferase (man), 378
Spinal cord, transmission, modi-fication by an interaction ofchiorpromazine and pheny-toin (cats), 270
Spleen, perfused, effect of cocaineand amphetamine on inhibi-tion of neurotranamission in(cat), 162
Stacey, N. H. and Klaassen, C. D.:Uptake of galactose, ouabainand taurocholate into centri-lobular and periportal en-riched hepatocyte subpopu-
lations, 634Steinbacher, T. E., see Voilmer,
R. R, 225Stewart, J. C., see McGovren, J.
P., 433Stewart, J. J.: Interactions of re-
serpine and morphine on ratintestinal transit, 521
Stimulationelectrical, comparison with am-
phetamine and tyramine ondopamine release from cau-
date nucleus (rabbits), 592vagal, effects in ischemic myo-
cardial blood flow (dogs), 347
Stobs, S. J., see Al-Turk, W. A.,492
Stone, C. A., see Gross, D. M., 552
Stone, C. A., see Sweet, C. S., 558Stramentinoli, G., see SChatZ, R.
A., 118
Stress, immobilization, quina-crine-blocked desensitization
of beta adrenoceptors after(rats), 334
Striatum, activation of adenylatecyclase by ethanol in (mice),129
Strum, W. B.: Characteristics ofthe transport of pteroylglu-tamate and amethopterin inrat jejunum, 329
Sweet, C S., Gross, D. M., Arbe-gast, P. T., Gaul, S. L, Britt,
P. M., Ludden, C. T, Weitz,D. and Stone, C. A.: Anti-hypertensive activity of
N-[(S)- i-(ethoxycarbonyl)-3-phenypropyl]-L-Ala-L-Pro
(MK-42i), an orally activeconverting enzyme inhibitor,
558
Sweet, C. S., see Gross, D. M., 552
Sympathomimetic agonists, com-parison of contractile re-sponses of basilar and pal-monary arteries to (rabbits),83
Takahashi, H. and Bufiag, R D.:Centrally induced cardiovas-cular and sympathetic nerveresponses to bradykinin inrats, 192
Taneja, A. K., see Meldrum, J. B.,275
Taurocholate, uptake into centri-lobular and periportal en-riched hepatocytes (rats), 634
Tenner, T. E., Jr., see Pang, P. K.T., 567
Terrell, J. A., see Pang, K. S., 339�-9-Tetrahydrocannabinol, car-
diovascular and autonomiceffects of (monkeys), 247
Thames, M. D., see Osborn, J. L,265
Thenot, J.-P., see Ruo, T. I., 357
Thioridazine, effects on ventricu-tar fibrillation in heart (dogs),39
Thurman, R. G., see Sonawane,B. R, 473
Toleranceto effects of naloxone on hype-
thalamic-pituitary-luteiniz-ing hormone axis (rat), 135
to ethanol, interactions with pi-mozide and clonidine (rats),459
Torda, T., Yamaguchi, I., Hirata,F., Kopin, I. J. and Axelrod,J.: Quinacrine-blocked damn-sitization of adrenoceptorsafter immobilization stress orrepeated injection of isopro-
terenol in rats, 334Toxicity
renal, by 4-ipomeanol meta-bolic activation (mice), 640
sex- and age-related, of acivicin(mice), 433
Tricycic antidepressants (see
specific drug)Triglyceride formation, liver, ef-
fect of morphine exposure(mice), 496
T#{252}rck, M., see Schultz, J. E., 28Turner, D., see Henderson, G. I.,
465
Tyramine, comparison with am-phetamine and electricalstimulation on dopaminerelease from caudate nucleus(rabbits), 592
Tyrosine hydroxylase, brain,phosphorylation by cyclicAMP-dependent protein lii-nase (cow), 647
Ulni, E. H., see Gross, D. M., 552
Uric acid, effects of furosemide,
ethacryrnc acid and chloro-thiazide on renal tubular han-dling of (chickens), 441
Urthaler, F., Woods, W. T.,James, T. N. and Walker, A.A.: Effects of adenosine onmechanical performance andelectrical activity in the ca-nine heart, 254
Valette, G., see Ribes, G., 172Valette, J. F., see Ribes, G., 172Valine, placental uptake, inhibi-
tion after maternal ethanolconsumption (rats), 465
Valproate, interaction withphenytoin and 5-(p-hydrox-yphenyl)-5-phenylhydantoin
(rats), 613Vascular response, to angiotensin
H, role of released catechol-amines in (dog), 104
Vas deferens, pharmacologicalcharacterization of a-opiatereceptors in (rats), 604
Vasodilator, effect of hydralazinein isolated renal artery (rab-
bit), 390Vassil, T. C., see Gross, D. M., 552Veins and arteries, comparison of
dependence on calcium forresponses to norepinephrineand potassium (dogs), 239
Verapamil, actions on Purkinje fi-bers from normal and in-farcted heart tissues (dogs),261
Verbeeck, R K., Gerkens, J. F.,Wilkinson, G. R and Branch,R A.: Disposition of furose-mide in functionally hepatec-
tomized dogs, 479Vogel, R. A., see Frye, G. D., 306Voile, R. L., see Lambert, J. J., 62Voilmer, R R, Boccagno, J. A.,
Steinbacher, T. E., Horovits,z. P. and Murthy, V. S.: Anti-
hypertensive activity of cap-topril (SQ 14,225), an orallyactive inhibitor of angioten-sin converting enzyme in con-scious two-kidney perine-
phritic hypertensive dogs,225
Voilmer, R R, Bush, E. N. andAbukhres, M. M.: Influenceof dietary sodium on reninangiotensin system involve-ment in sodium nitroprussidehypotension in consciousrats, 580
Wads, H., see Kamisaki, Y., 419
Walker, A. A., see Urthaler, F.,254
Wanstall, J. C., see Bryan, L J.,404
Warltier, D. C., see Buck, J. D.,
347Watters, K., see Reingold, D. F.,
510Wei, E. T.: Enkephalin analogs
and physical dependence, 12Weiner, I. M. and Roth, L: Renal
excretion of cimetidine, 516
662 Index
Weiss, G. B., see Hester, R K.,239
Weitz, D., see Gross, D. M., 552
Weitz, D., see Sweet, C. S., 558Wenger, H. C., see Gross, D. M.,
552Wiener, S. G., Shoemaker, W. J.,
Koda, L Y. and Bloom, F. E.:Interaction of ethanol andnutrition during gestation:Influence on maternal and
offspring development in therat, 572
Wiesmann, U. N., see Roscher, A.A., 428
Wilkinson, G. H., see Verbeeck, RK., 479
Wilson, W. A., Jr., see Gospe, S.M., Jr., 377
Woods, W. T., see Urthaler, F.,254
)W#{252}ster,M., see Schulz, R., 604
Wyatt, R� J., see Karoum, F., 321
Yaffe, S. J., see Sonawane, B. R.,
473Yagura, T., see Kamisaki, Y., 419Yamaguchi, I., see Torda, T, 334
Yang, M. C. M., see Pang, P. K.T., 567
Young, W. S. Ill, Niehoff, D., Ku-liar, M. J., Beer, B. andLippa, A. S.: Multiple benzo-
Vol. 216
diazepine receptor localize-tion by light microscopic ra-
diohistochemistry, 434
Zehr, J. E., see Schultz, H. D., liiZimmerman, J. B., see Jackson,
E. K., 24Zmuda, M. J., see Shideman, J.
R, 441
Top Related