Features and Benefits of Snap Combo Plus
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Antigen and Antibodies -The Battle Begins The body has an army of soldiers consisting of white cells and
antibodies waiting for the invasion by the enemy (antigens). The antigen stimulates production of the antibody. When the
antigen and antibody come into contact, the antibody locks on to the antigen. This process is called “binding.” The result is the antigen antibody immune complex.
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Why should a vet use IDEXX products rather than competition?
IDEXX Snap Combo is the only test that can identify the proteins P15, P24, and GP40.
All of these antigen proteins are indicators of the FIV Virus.
IDEXX can identify more cases of FIV than any other test on the
market because the other tests only identify the protein GP40.
Only in-clinic test that uses Elisa Technology Conjugate – enhances ur - identifies weak positives
Bi-directional Flow – twice the time allows for greater sensitivity
Wash Solution – eliminates non-specific binding
Amplification of results – identifies weak positives
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Enzyme-Linked Immuno-Sorbent Assay
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SNAP Technology Only ELISA technology rapid test in the market
Bi-directional flow of samples and wash allows for efficient washing
of the samples which removes any background interference. This
makes the test easy to read even when the sample is damaged.
True blue color means the test spots amplify blue, not red (the color
of blood) like the competitors (in US)
Highest sensitivity due to the enzyme amplifier that is present in the
conjugate
Highest specificity due to wash step
Patented technology
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What is Sensitivity?Sensitivity = # of detected positives / # of known
positives = a true positive. Example: 100 known positive parvo dogs. If Snap test
detects 95 positive dogs from the original 100 then Snap has 95% sensitivity. 5 false negatives.
We missed 5 samples that were true positives.
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What is Specificity? Specificity = # of detected negatives / # of known negatives = a
true negative. If Snap called a true negative a positive = false
positive.
For example, if 100 dogs are truly negative for the Parvo Virus but
our test says that 5 are positive than our test is 95% specific.
It falsely identified 5 dogs as positive even though they do not have
Parvo.
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How is Accuracy Determined? Accuracy is presented in a percentage form based upon the
sensitivity and specificity. The higher the sensitivity and specificity, the more accurate the assay. Accuracy = sensitivity + specificity / 2.
Example: 95(SENS) + 100(SPEC) divided by 2 = 97.5%.
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10 © 2005 IDEXX LABORATORIES, INC. | Proprietary and Confidential | Apr 20, 2023
11 © 2005 IDEXX LABORATORIES, INC. | Proprietary and Confidential | Apr 20, 2023
- Amplification of signal via enzyme reactions (ELISA)
(increased sensitivity)
- Bi-lateral flow (SNAP)
- hits reactive spot twice, increasing signal- includes wash step for clear background
(increased specificity)
-Simultaneous detection of:FIV with FeLV
Why Snap®?
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Signal Amplification
The Snap® device uses an enzyme to AMPLIFY the signal from one
antigen or antibody molecule to 100s of color molecules. Think of one
blue bubble bursting onto 100 clear bubbles turning ALL the bubbles
blue. This technology allows are tests to achieve the HIGHEST
sensitivity
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The Wash Step The Snap® device includes a wash step that removes non-specific
binding. Think of the wash as a cleaner that clears away any of the blue
that sticks to the wrong types of bubbles. This allows us to achieve the
Highest specificity.
14 © 2005 IDEXX LABORATORIES, INC. | Proprietary and Confidential | Apr 20, 2023
SNAP Technology Only ELISA technology rapid test in the market
Bilateral flow of samples and wash allows for efficient washing of the
samples which removes any background “noise”. This makes the test easy
to read even with bad samples.
True blue color means the test spots amplify blue, not red (the color of
blood) like the competitors
Highest sensitivity due to the enzyme amplifier that is present in the
conjugate
Highest specificity due to wash step
Patented technology
Most used test in the Veterinary industry
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