Group 7
Caringal, Rizzalaine Parallag Diane
Dueñas, Angelica Ranjo, Johanna Marie
Pagkalinawan, Erikka Marie Semilla, Jean Darlene
ANESTHETICS
Name Structure IUPAC Name Trade Names Manufacturer Selling Price Dosage Form and Strength
Chemical Indication
Pregnancy Category
Mepivacaine (RS)-N-(2,6-dimethylphenyl)- 1-methyl-piperidine-2-carboxamide
Carbocaine 2% (Mepivacaine hydrochloride)
Polocaine 3% (Mepivacaine hydrochloride)
Polocaine – MPF (Mepivacaine hydrochloride)
Hospira, US
Dentsply Pharmaceutical, US
APP Pharmaceutical, US
$17.75
$12.25
$16.75
Injectable solution (1%, 1.5%, 2%, 3%)
Injectable solution (1%, 1.5%, 2%, 3%)
Injectable solution (1%, 1.5%, 2%, 3%)
This medication is a local anesthetic, prescribed for inducing local or regional analgesia and anesthesia during surgical procedures, labor, or delivery. It works by preventing nerves from transmitting painful impulses to the brain.
C (Either studies in animals have revealed adverse effects on the fetus and there are no controlled studies in women or studies in women and animals are not available.)
Isoflurane Aerrane
Florane
Baxter Healthcare
Singapore Pharmawealth Lifesciences
P1,500 Inhalation solution100mL x1’s
Inhalation solution 100% x 100mL x 1’s
General inhalation anesthetic
B (Either animal-reproduction studies have not demonstrated a foetal risk but there are
Forane
Isocane
Phil Pharmawealth/Minrad Isoflurane
Abbott
Lunan
Minrad
P 4,327.58 Inhalation solution100mL x1’s
Inhalation solution100mL x1’s
Inhalation solution100mL x1’s
no controlled studies in pregnant women or animal reproduction studies have shown any adverse effects.)
Benzocaine Ethyl 4-aminobenzoate
Auralgan
United Home Burn Ointment
Orajel (UK)
Dermoplast (US)
Anbesol (US)
Wyeth
United Home
Church & Dwight UK LtdPretige Brands, Inc.
Pfizer
Pfizer
559.03 php
70.0php (15g)
92.0php (30g)
5.25 pounds
10.79 dollars
6.27 dollars
Otic Solution (14mg/mL)
Ointment (10mg/g)
Mouth Gel ( 10% w/w)
Spray (20%)
Oral gel (20%)
Benzocaine is used to reduce pain or discomfort caused by minor skin irritations, sore throat, sunburn, teething pain, vaginal or rectal irritation and many other minor pain on a surface of the body
C(Either studies in animals have revealed adverse effects on the fetus and there are no controlled studies in women or studies in women and animals are not available.)
Prilocaine and Lidocaine
Lidocaine: 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide
Prilocaine: (RS)-N-(2-methylphenyl)-N2-propylalaninamide
Asthesia
Prilox
Emla
Emla D.A.C
Oraqix
Unichem, India
Neon Labs Ltd., Maharashtra, India
AstraZeneca, Canada
DAC, Iceland
Dentsply Pharmaceutical, United States
360.00 Indian Rupees
56.20 Indian Rupees
$39.00 (USD)
109.95 ISK
$99.95 (USD)
Cream (lidocaine 2.5%, prilocaine 2.5 %)
Ointment (lidcaine 25mg, prilocaine 25 mg)
Patch (1 g of Emla Emulsion)
Patch (1g of Emla Emulsion)
Periodontal Gel 2.5 %/2.5 %
Local anesthetic B(Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal reproduction studies have shown any adverse effects.)
Bupivacaine (RS)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
Ultracaine
Pivacaine
Bupicaine Heavy
Pivacaine- D
Jayson Pharmaceuticals Ltd.
ACI Ltd.
Chemist Laboratories Ltd.
ACI Ltd.
0.25% x 20ml vial: 35.40 IP; 0.5% x 30ml vial: 60.00 IP
0.25% x 20ml vial: 45.00 IP
4ml amp x 10s pack: 280.00 MRP
4ml amp x 10s pack:
0.25% or 0.5%Solution for injection
0.25%Solution for injection
80mg/mlSolution for injection
80mg/mlSolution for
Bupivacaine is indicated for single dose-infiltration into surgical site to produce postsurgical anesthesia. It is also indicated for Peripheral nerve block, sympathetic nerve block, and caudal blocks. However it is
C (it has an action that crosses the placenta it has been approved as an obstetrical anesthesia. However Bupivacaine is excreted into human milk. The risk of continuing and
BUPI Plain Popular Pharmaceuticals Ltd.
300.00 IP
0.5% x 30ml vial: 60.00 MRP
injection
0.5%Solution for injection
most commonly used as local anesthetic in epidural anesthesia during labor.
discontinuing the drug is being discussed with the patient.)
LIDOCAINE HCl
2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide
Euro-Med Lidocaine HCl
Elin Lidocaine HCl
Phil Pharmawealth/Atlantic LidocaINE
Xepacaine
Xylocaine
Euro-Med
Elin
Atlantic Lab
Gland Pharma
AstraZeneca
(2mL) P 8.96/amp(5mL) P 12.32/amp(20mL) P 36.96/vial(50mL) P 66.08/vialP27.50 P65
P 1,757
P2,125
20 mg /mL 2%Solution for injection
2% x 10mL50mL
20mg/mL
20mg/mL
10mg/dose(10%)(2%)
Local and regional anesth: local infiltration and peripheral and central nerve block.
B ( Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women )
ANTHELMINTICSGENERIC NAME IUPAC NAME STRUCTURE BRAND NAME INDICATION PREGNANCY
CATEGORY1.Albendazole methyl N-[6-
(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate
1.HYEMEX chewable tab 400 mg (P25/tab) manufactured by: Blue sky
Treatment of single & mixed intestinal nematode infections including ascariasis, enterobiasis &
Category CEither studies in animals have revealed adverse effects on the foetus
2.ALMEX chewable tab 400 mg (25s pack/94 MRP) manufactured by: Square Pharmacy[INDIA]
3. ZENTEL 200mg/5mL suspension (P437/bottle) manufactured by: GSK
4.ANTHEL 400mg/tab (500s pack/200 MRP) manufactured by: Seema Pharmaceutical Ltd.
5.AZOLE 400 mg/tab (20s pack/80 MRP) manufactured by: Bio-pharma Laboratories Ltd.
trichuriasis. (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
2.Mebendazole methyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate
1.BENDEX 100mg & 500 mg/tab (100mg x 30s pack/22.20 MRP; 500mg x 30s pack/65.99 MRP) BENDEX 100mg/5ml suspension (30ml bot/14.83 MRP)manufactured by: Gaco Pharmaceuticals
2.ERMOX 100 mg/tablet (100mg x
Broad-spectrumanthelmintic indicated for the treatment of nematode infestations, including roundworm, hookworm, whipworm, threadworm, pinworm, and the intestinal form of trichinosis prior to its spread into the tissues beyond the digestive tract
Mebendazole is Pregnancy Category C, which means that it has been shown to cause ill effects in pregnancy in animal models and there are no adequate studies of its effects in human pregnancy. It is unknown whether it can be passed by breast feeding.
150s: 111.00 MRP)
ERMOX 100mg/5ml syrup (30ml bot/14.83 MRP)Manufactured by: Square Pharmaceuticals Ltd.3.MEBENDAZOLE 100mg/tab (100 mg x 60 strips/42.60 MRP) manufactured by:Gonoshasthaya Pharmaceuticals Ltd.
4.HELBEN 100 mg/5ml suspension (30m bot/10.60 MRP) manufactured by: Ad-din pharmaceuticals ltd.
5.MEBANTRIN 100mg/tab (30s pack/22.50 MRP) Manufactured by: Pharmadesh Laboratories Ltd.
*all from Bangladesh
3.Ivermectin 22,23-dihydroavermectin B1A + 22,23-dihydroavermectin B1B
1.AGIMECT 12 mg tab (1x4tabs=175 indian rupees) Manufactured by: Aegis Pharmaceuticals [INDIA]
2.ASCAPIL 6mg tablet (1 tab= 16.27 rupees) Manufactured by: Nicholas Piramai India Ltd. [INDIA]
3. AVERM PLUS 12 mg tab (1x5tabs= 105 rupees) Manufactured by: Biotavia Labs Pvt Ltd. India
4. BIOVER 6mg tab (1x10tabs= 2.55 US dollars) Manufactured by: Biogenetic Pharmaceuticals[USA]
5. EVRINA 3mg tab (1x50tabs= 8.50 US dollars) Manufactured by: Pride Healthcare [USA]
Used in humans in the treatment of onchocerciasis and effective against other worm infestations such as strongyloidiasis, ascariasis, trichuriasis, filariasis, and enterobiasis.
B3 (Australia), C (US)
4. Pyrantel Pamoate 4-[(3-Carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid; 1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine
1.DELENTIN 50mg/ml syrup (10ml bot/11.42 MRP) Manufactured by: Renata Ltd.[BANGLADESH]
2.MELPHIN 125mg/tab (100s pack/166.00 MRP) Manufactured by: Beximco Pharmaceuticals Ltd. [BANGLADESH]
3. WORMEX 50mg/ml Suspension (10ml bo/11.00 MRP) Manufactured by: Hallmark Pharmaceuticals Ltd.
4.COMBANTRIN 125mg/5ml suspension (P153.50/bot) Manufactured by: Zuellig Pharma
5. NEMOCID 250mg tab (2.31 Rs/3 tablets) Manufactured by: Intima (IPCA Laboratories Ltd.) [INDIA]
Single or mixed infestations by threadworm, pinworm, roundworm, hookworm, Trichostrongylus colubriformis & orientalis.
Category C
5. Praziquantel 2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
1.BILTRICIDE 600 mg tab Manufactured by: Bayer phils Inc.
2. FLUXIDE 600mg/5ml suspension Manufactured by: Blue Sky Trading Co., Inc.
3. Endure Medical Praziquantel 600 mg tab Manufactured by: Endure Medical Inc.
4. Swiss Pharma Praziquantel 600mg film coated tablet Manufactured by: Swiss Pharma Research Labs Inc
5. Wormguard (combination of Febantel/Pyrantel Pamoate/ Praziquantel) 150mg/144mg/50mgManufactured by: Fanfreluche Enterprises Inc.
*No available current price available
Trematodicide provided for the oral treatment of schistosome infections and infections due to liver fluke.
Category B, no proven risk for humans, but it is advised that Praziquantel must not be taken by mother if breast feeding..
GROUP 6 ANTIDIABETIC
Name Structure IUPAC Name 5 Trade Names (with manufacturer and selling price)
Dosage forms and strengths
Clinical Indication Pregnancy category
Glibenclamide
5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-benzamide
Euglucon (Roche) 10.81 pesos/tab
Euglotab (Acme) 4.75pesos/tab
Daonil (Sanofi Aventis) 5.47pesos/tab
Allase (Interphil) 6.09 pesos/tab
Orabetic (Biolab) 6.16 pesos/tab
Euglucon tablet 5 mg
Euglotab tablet 5 mg
Daonil tablet 5 mg Allase tablet 5 mg Orabetic tablet 5
mg
Diabetes Meliitus type 2
Category C
Gliclazide
1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea
Diamicron (Servier) P910.00/pack
Dianorm (Merck) P761.58/pack
Gluconil (Biolab)P644.00/pack
Glubitor (LR Imperial) P708.27/pack
Clibite (Korea United Pharma) P600.32/pack
Diamicron tablet 80 mg
Dianorm tablet 80 mg
Gluconil tablet 80 mg
Glubitor tablet 80 mg
Clibite tablet 80 mg
For control of hyperglycemia in gliclazide-responsive diabetes mellitus of stable, mild, non-ketosis prone, type 2 diabetes. It is used when diabetes cannot be controlled by proper dietary management and exercise or when insulin therapy is not appropriate.
Category C
Name Structure IUPAC Name 5 Trade Names (with manufacturer and selling price)
Dosage forms and strengths
Clinical Indication Pregnancy category
Metformin HCl1-carbamimidamido-N, N-dimethylmethanimidamide
Gludin (Med Choice Pharma) P3.20/tab
Neoform (GX International Inc.) P3.35/tab
Diafat (Sandoz Philippines Corporation) P5.70/tab
Nidcor (Pharma Nutria)P4.32/tab
Glumet (L.R. Imperial, Inc.) P7.22/tab
For people with Type 2 diabetes. Metformin is sometimes used in combination with insulin or other medications, but it is not for treating Type 1 diabetes.
Category B
Pioglitazone HCl
5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione hydrochloride (1:1)
Actos (Takeda Pharmaceutical Company )
15 mg x 30’s (Php2,027.30)30 mg x 30’s (Php 3,254.55) Glucozone (Vitalink) 500 mg x 100’s (Php 320/box ; Php 3.20/tab) Piozone (LR Imperial, Inc)
15 mg x 10’s, 30’s (Php 509.45/box)30 mg x 10’s, 30’s (Php 679.25/box) Prialta (OEP Philippines)
15 mg x 50’s (Php 794.18)30 mg x 50’s (Php 1,069.09)45 mg x 50’s (Php 1,069.09) Zolid (Getz Pharma)15 mg x 14’s (Php 249.50)
30 mg x 14’s (Php 261.75)45 mg x 14’s (Php 336.50)
Actos tablet 15 mg, 30 mg
Glucozone tablet 500 mg
Piozone tablet 15 mg, 30 mg
Prialta tablet 15 mg, 30 mg, 45 mg
Zolid tablet 15 mg, 30 mg, 45 mg
Used to lower high blood sugar associated with type 2 diabetes. It helps insulin to work more effectively. By keeping blood sugar at a desired level, It can help prevent or delay the long-term problems associated with uncontrolled high blood sugar (e.g., kidney disease, eye problems, nerve problems, heart disease). It increases insulin sensitivity in muscle and adipose tissue, and inhibits hepatic gluconeogenesis
CategoryC
Name Structure IUPAC Name 5 Trade Names (with manufacturer and selling price)
Dosage forms and strengths
Clinical Indication Pregnancy category
Vildagliptin
(2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}pyrrolidine-2-carbonitrile
Galvus (Novartis Healthcare) 28's(P760.20/box)
Xiliarx (Novartis AG)
Jalra-M (US Vitamins Limited) 10’s (198 Indian Rupee or
P142.34) Zomelis (Piramal Healthcare) 14’s( 270 Indian Rupee or
P194.13)
Galvus tablet 50mg
Jalra-M
tablet 50mg, 500mg
Zomelis 50mg
ANTILIPIDEMIC DRUGS
Name: SimvastatinStructure:
IUPAC Name: (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
Manufacturer: Price:
Trade Names: 1. Vidastat 20mg Unilab Php 43.39 /tab2. Cholestad 20mg Littman Drug Corp Php 2,1.37/100 tab3. Zocor 20mg Merck & Co. Php 41.22/tab
4. Alvastin 10mg Allied Chemicals & Pharmaceuticals Pvt.Ltd.
Php 5.04/tab
5. Zosta 40 mg US Vitamins Limited Php 15.00/tabDosage Forms and Strength: Tablet 5 mg, 10 mg, 20 mg, 40 mg,Clinical Indication: For the treatment of hypercholesterolemia and for the reduction in the risk of cardiac heart disease
mortality and cardiovascular events. It can also be used in adolescent patients for the treatment of heterozygous familial hypercholesterolemia.
Pregnancy Category: X
Name: Fenofibrate
Structure:
IUPAC Name: propan-2-yl 2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoate
Trade Names:Manufacturer: Price:
1. Fenoflex LR Imperial, Inc. 30's (P1030.49/box)
2. Fenogal SMB Technology 30's (P885.00/pack)
3. Lofibra OEP Phils. Inc 50's (P1090.00/pack)
4. Lipway SR Cathay Drug Co. Inc. 30's (P1041.60/pack)
5. Trolip Gracio Med Phils., Inc. 30's (P823.73/pack)
Dosage Forms and Strength: 160 mg capsule, 200 mg capsule, 250 mg capsule, 300 mg capsule
Clinical Indication: It is mainly used to reduce cholesterol levels in patients at risk of cardiovascular disease. It reduces both low-density lipoprotein (LDL) and very low density lipoprotein (VLDL) levels, as well as increasing high-density lipoprotein (HDL) levels and reducing triglycerides level.
Pregnancy Category: C
Name: RosuvastatinStructure:
IUPAC Name: (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
Trade Names:Manufacturer: Price:
1. Bestor Biocon Limited P32.40/10 tabs
2. Fortius Nicholas Piramal India Ltd. P35.28/10 tabs3. Crestor AstraZeneca P1,730/30 tabs
4. Rosucol Ajanta Pharma Phil P493.69/30 tabs
5. Rustor InnoGen Pharma P1,065/30 tabs
Dosage Forms and Strength: 5mg, 10mg, 20mg, and 40mg film-coated tabletsClinical Indication: Rosuvastatin is used for the reduction of blood total cholesterol, HDL cholesterol and triglyceride levels,
and to increase HDL cholesterol levels. Rosuvastatin also is used for reducing the risk of heart attacks, stroke, and arterial revascularization procedures in patients without clinically evident coronary heart disease but with multiple risk factors for heart disease.
Pregnancy Category: X
Name: Fluvastatin Structure:
IUPAC Name: (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
Trade Names:Manufacturer: Price:
1. Canef (EU) 20 & 40 mg
AstraZeneca 84’s (P2,680.70)84’s (P2,777.32)
2. Cranoc (US) 20 & 40 mg
Astellas 50’s (P2567.29)50’s (P3153.52)
3. Lescol 40 mg Novartis Pharmaceutical 28’s (P1,650)
4. Lescol XL 80 mg Novartis Pharmaceutical 28’s (P1,912.65)5. Liposit (US) 20 & 40 mg
Ferrer International 28’s (P1890.29)28’s (P2541.67)
Dosage Forms and Strength: 20 mg Capsule, 40mg Capsule, 40 mg Tablet, 80mg TabletClinical Indication: To be used as an adjunct to dietary therapy to prevent cardiovascular events. May be used as secondary prevention in
patients with coronary heart disease (CHD) to reduce the risk of requiring coronary revascularization procedures, for reducing progression of coronary atherosclerosis in hypercholesterolemic patients with CHD, and for the treatment of primary hypercholesterolemia and mixed dyslidipidemiaTo be used as an adjunct to dietary therapy to prevent cardiovascular events. May be used as secondary prevention in patients with coronary heart disease (CHD) to reduce the risk of requiring coronary revascularization procedures, for reducing progression of coronary atherosclerosis in hypercholesterolemic patients with CHD, and for the treatment of primary hypercholesterolemia and mixed dyslidipidemia.To be used as an adjunct to dietary therapy to prevent cardiovascular events. May be used as secondary prevention in patients with coronary heart disease (CHD) to reduce the risk of requiring coronary revascularization procedures, for reducing progression of coronary atherosclerosis in hypercholesterolemic patients with CHD, and for the treatment of primary hypercholesterolemia and mixed dyslidipidemia.
Pregnancy Category: X
Name: AtorvastatinStructure:
IUPAC Name: 7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate
Trade Names:Manufacturer: Price:
1.Lipitor 10mg Pfizer 100's (P3272.75/pack)2. Ator-10 InnoGen Pharma 30's (P676.50/pack)3. Avamax 20mg Therapharma 100's (P28.57/pack)
4. Atorwin 10mg Sanofi-Aventis 30's (P552.27/pack)5. Xantor 80mg Sandoz 30's (P34.00/film-coated tab)
Dosage Forms and Strength: 10 mg capsule, 20 mg capsule, 40 mg capsule, 80 mg capsuleClinical Indication: Atorvastatin is used for the treatment of elevated total cholesterol, LDL, and triglycerides and to elevate
HDL cholesterol. The effectiveness of atorvastatin in lowering cholesterol is dose-related, meaning that higher doses reduce cholesterol more. It prevents angina, stroke, heart attack, hospitalization for congestive heart failure, and revascularization procedures in individuals with coronary artery disease. It also reduces the risk of myocardial infarction (heart attack), stroke, angina and revascularization procedures in adults with multiple risk factors for coronary artery disease. Atorvastatin also prevents heart attacks and strokes in patients with type 2 diabetes with multiple risk factors for coronary artery disease.
Pregnancy Category: X
ANALGESIC / ANTI-INFLAMMATORY DRUGS
Generic Name
Structure IUPAC name Trade Name
Manufacturer
Selling Price Dosage Form/s
Strengths
Clinical Indication
Pregnancy Category
Celecoxib
4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]
benzene-1-sulfonamide
Aubrex Corbridge P26.00/cap Capsule 200 mg Treatment of rheumatic arthritis, juvenile
idiopathic arthritis,
osteoarthritis, signs and
symptoms of ankylosing spondylitis,
and of adenomatous
colorectal polyps, and
management of acute pain
Category C OR
Category D (in third
trimester or near
delivery)
Brexen Xeno P19.80/cap Capsule 200 mg
Celcoxx Getz Pharma
P18.83/cap
Capsule
100 mg
P27.24/cap 200 mg
P42.27/cap 400 mg
Celebrex Pfizer
P41.66/cap
Capsule
100 mg
P58.91/cap 200 mg
P79.50/cap 400 mg
Celeflam Flamingo P17.66/cap Capsule 200 mg
Diclofenac
2-[2-(2,6-dichlorophenyl-
amino)phenyl]acetic acid
Difenax GXI P5.57/tab Tablet 50 mg Treatment of rheumatic arthritis,
osteoarthritis, juvenile
rheumatic arthritis,
ankylosing spondylitis, and painful
inflammation and swelling
Category C OR
Category D (in third
trimester or near
delivery)
Cataflam Novartis Healthcare
P13.14/tab Sugar-coated Tablet
25 mg
P22.25/tab 50 mg
Clofil Filadams P6.00/tab EC Tablet 50 mg
Votan Taiwan Biotech
P18.00/tab Tablet 100 mg
Arthrotec Pfizer (USA) P39.20/tab MR Tablet 75 mg
Generic Name
Structure IUPAC name Trade Name
Manufacturer
Selling Price Dosage Form/s
Strengths
Clinical Indication
Pregnancy Category
Ibuprofen (RS)-2-[4-(2-methyl propyl)phenyl]pro-
panoic acid
Advil Pfizer Consumer
P6.83/caplet Caplet 200 mg Management of mild to moderate
Category C OR
Category D P74.25/bottle (60 mL)
Oral Suspension
100 mg/ 5 mL
paint and inflammation
(menstrual pain, dental
pain, headaches, migraines,
sprains, strains), and treatment of
(in third trimester or near
delivery)
P7.39/cap Softgel Capsule
200 mg
Brufen Abbott
P73.50/bottle (60 mL)
Oral Suspension
100 mg/ 5 mL
P13.13/tab Tablet 600 mg
Dolan FP Pediatrica
P70.75/bottle (15 mL)
Oral Drops 100 mg/ 2.5 mL
P115.51/bottle (60 mL) Oral
Suspension
200 mg/ 5 mL
P69.31/bottle (60 mL)
100 mg/ 5 mL
Faspic Zambon P22.40/tab Tablet 400 mg
Midol Invida
P6.14/tab
Tablet
200 mg Category B OR
Category D (in third
trimester)P14.55/tab 400 mg
Mefenamic Acid
2-[(2,3-dimethylphenyl)
amino]benzoic acid
Hispen Genesis P5.50/tab Tablet 500 mg For the relief of pain
including muscular, rheumatic, traumatic,
dental, post-op and post partum pain,
headache, and juvenile rheumatic
arthritis
Category C OR
Category D (in third
trimester or near
delivery)
Afligec Filadams P6.20/caplet Caplet 500 mg
Dolfenal WestmontP10.83/tab
Tablet250 mg
P20.85/tab 500 mg
Dolsten Medic+AidP2.95/cap
Capsule250 mg
P4.95/cap 500 mg
Gisfen S V More P5.54/tab Tablet 500 mg
Generic Name
Structure IUPAC name Trade Name
Manufacturer
Selling Price Dosage Form/s
Strengths
Clinical Indication
Pregnancy Category
Tramadol(±) cis-2-
[(dimethylamino) methyl]-1-(3-
Clomadol Mount Mettur
P104.00/amp (1 mL)
Ampule 50 mg/ mL
Relief of p mild to
moderate to Category C
Dolotral Stada P17.58/cap Capsule 50 mg
methoxyphenyl) cyclohexanol hydrochloride
severe pain (chronic back
pain, neuropathic pain, surgical
P106.80/amp (2 mL)
Ampule 100 mg/ 2 mL
Tramid Euro-Med P84.00/amp (1 mL)
Ampule 50 mg/ mL
Pengesic Hovid P12.50/cap Capsule 50 mg
Peptrad Shin PoongP52.00/amp
(1 mL) Ampule50 mg/
mL
ANTIDEPRESSANTS
Name Citalopram HBr
Structure
IUPAC Name 5-Isobenzofurancarbonitrile
5 Trade Names 1. Feliz 20
Manufactured by Torrent
Selling price: 3 × 10's (P1760.00/box)
2. Lupram
Manufactured by Lundbeck
Selling price: 14's (P1670.00/pack)
3. Celexa
Manufactured by Forest Laboratories (US)
Selling price: N/A
4. Cipramill
Manufactured by Lundbeck (US)
Selling price: N/A
Dosage Forms & Strengths Tablets: 10, 20, and 40 mg
Solution: 10 mg/5 ml
Clinical Indication Depression in patients whose diagnosis corresponds most closely to the DSM-III and DSM-III-R category of major depressive disorder
Pregnancy Category Pregnancy category: C
Use late in the third trimester associated with complications in newborns and may require prolonged hospitalization, respiratory support, and tube feeding.
Name Escitalopram
Structure
IUPAC Name (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
5 Trade Names 1. Nexito
Manufactured by Jewim Pharma
Selling price: 10mg 100’s (P474.50/box)
2. Feliz S 10/ Feliz S 20
Manufactured by Torrent Pharma
Selling price: Feliz s 10 100's (P3300.00/box)
Feliz s 20 100’s (P6000.00/box)
3. Jovia
Manufactured by Medichem
Selling price: 10mg 28's (P1188.21/pack)
4. Lexapro
Manufactured by Lundbeck
Selling price: 5mg 28's (P1650.00/pack)
10mg 14's (P1500.00/pack)
20mg 28's (P6000.00/pack)
5. Morcet
Manufactured by Searle
Selling price: 20mg 250’s (P7553.00/pack)
Dosage Forms & Strengths 5mg, 10mg, 20mg film coated tablets
5mg/5ml oral solution
Clinical Indication For major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive-compulsive disorder, and panic disorder(significant behavioral change).
Pregnancy Category Category C
Use late in the third trimester associated with complications in newborns and may require prolonged hospitalization, respiratory support, and tube feeding.
Name Sertraline HCl
Structure
IUPAC Name (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
5 Trade Names 1. Exulten
Manufactured by: Medichem
Selling price: 30's (P1071.29/pack)
2. Serenata
Manufactured by: Torrent
Selling price: 30's (P1858.50/pack)
3. Zolodin
Manufactured by: Medchoice Pharma
Selling price: 30's (P38.00/tab, P1140.00/box)
4. Zoloft
Manufactured by: Pfizer
Selling price: 28's (P3717.78/pack)
Dosage Forms & Strengths Tablet: 25mg, 50mg, 100mg
Solution: 20mg/ml
Clinical Indication Treatment of symptoms of depression, including depression accompanied by symptoms of anxiety, in patients w/ or w/o history of mania. Treatment of obsessive-compulsive disorder (OCD), ped OCD, panic disorder w/ or w/o agoraphobia, post traumatic stress disorder (PTSD), social phobia & premenstrual dysphoric disorder (PMDD).
Pregnancy Category Category C or Category D (if taken in the 2nd half of pregnancy)
Name Fluoxetine HCl
Structure
IUPAC Name N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
5 Trade Names 1. Motivest
Manufactured by: Medichem Pharmaceuticals, Inc.
Selling price: 30’s (P974.33/pack)
2. Neuxetin
.Manufactured by: Korea United Pharma (Korea)
Selling price: 30’s (P1230.00/pack)
3. Prodin
Manufactured by: MedChoice Pharma, Inc.
Selling price: P38.00/cap, 30’s (P1140.00/box)
4. Prozac 20
Manufactured by: Eli Lilly (USA)
Selling price: P125.00/cap
5. Prozyn
Manufactured by: Platinum Pharmaceuticals Ltd. (Pakistan)
Selling price: 30’s (P900.00/box)
Dosage Forms & Strengths Capsule: 20mg
Syrup: 20mg/5mL
Clinical Indication Management of generalized anxiety disorder, obsessive compulsive disorder, panic disorders w/ or w/o agoraphobia, social phobia & posttraumatic stress disorder; bulimia nervosa. Treatment of premenstrual dysphoric disorder.
Pregnancy Category Category C
ANTIDEPRESSANTS
Name Paroxetine Hydrochloride
Structure
IUPAC Name (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine;hydrochloride
5 Trade Names 1. Paxil
Manufactured by: GlaxoSmithKline (GSK)
Selling price: Php 70.30/tab
2. Seroxat
Manufactured by: GlaxoSmithKline (GSK)
Selling price: 30’s Php 1,792.80/
3. Pexeva
Manufactured by: Noven Pharmaceuticals, Inc.
Selling price: N/A
4. Brisdelle
Manufactured by: Noven Pharmaceuticals, Inc.
Selling price: N/A
5. Panex
Manufactured by: Brown & Burk Phils.
Selling price: Php 79.02/tab
Dosage Forms & Strengths Tablet: 10 mg, 20 mg, 30 mg & 40 mg
Oral Suspension: 10mg/5mL
Clinical Indication This medication is an SSRI antidepressant, prescribed for major depression, obsessive-compulsive disorder, panic disorder, social anxiety and generalized anxiety disorder. It increases the amount of serotonin, a natural substance in the brain that helps maintain mental balance.
Pregnancy Category Pregnancy category: D
Infants exposed to paroxetine in the first trimester of pregnancy have an increased risk of congenital malformations, particularly cardiovascular malformations.
ANTIHISTAMINESA. Name: Cetirizine diHCl
Structure:
IUPAC name: (±)-[2-[4-[(4-chlorophenyl)phenylmethyl]-1- piperazinyl]ethoxy]acetic acidTrade Name Manufacturer Selling Price
Zyrtec Duncan Oral drops 10 mg/mL: 10 mL x 1's (P377.00/bottle)Oral solution 1 mg/mL: 30 mL x 1's (P205.00/bottle) 60 mL x 1's (P392.00/bottle)Tablet 10 mg: 100's (P3667.00/box)
RiteMED Cetirizine RiteMED Tablet 10 mg: 100's (P2075.00/box, P20.75/tab)
Virlix GlaxoSmithKline Film-coated tablet 10 mg: 50's (P2300.00/pack)Oral drops 10 mg/mL: 10 mL x 1's (P391.00/bottle)Oral solution 1 mg/mL: 30 mL x 1's (P221.80/bottle)
Prixlae Shou Chan Film-coated tablet 10 mg: 100's (P2150.00/pack)
Allerkid Pediatrica Oral drops 2.5 mg/mL: 10 mL x 1's (P142.00/bottle)Syrup 5 mg/5 mL: 30 mL x 1’s (P130.00/bottle) 60 mL x 1’s (P212.26/bottle)
Dosage Form and Strength: tablet 10 mg oral drops 10 mg/mL and 2.5 mg/mL oral solution 1 mg/mL syrup 5 mg/ 5 mL
Clinical Indication: Cetirizine diHCl is indicated for the relief of symptoms associated with perennial allergic rhinitis due to allergens such as dust mites, animal
dander and molds in adults and children 6 months of age and older. Symptoms treated effectively include sneezing, rhinorrhea, postnasal discharge, nasal pruritus, ocular pruritus, and tearing.
Cetirizine diHCl is also indicated for the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria in adults and children 6 months of age and older. It significantly reduces the occurrence, severity, and duration of hives and significantly reduces pruritus.
Pregnancy Category: Category B: Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or
animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimester).
B. Name: LoratadineStructure:
IUPAC name: ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11 ylidene)-1-piperidinecarboxylate
Trade Name Manufacturer Selling PriceClaritin Schering-Plough Syrup 5 mg/5mL:
30 mL x 1's (P278.91/bottle)Tablet 10 mg: 100's (P4971.82/box)
Onemin Ampotex Tablet 10 mg: 12's (P334.88/pack)
Allerta Amherst Tab 10 mg: 50's (P1000.00/box)Syrup 5 mg/5mL: 60 mL x 1's (P200.00/bottle)
Lorano Sandoz Tab 10 mg: 50's (P850.00/pack)
Lorange Willore Pharma Tab 10 mg: 100's (P15.00/tab)
Dosage Form and Strength: tab 10 mg syrup 5 mg/5mL
Clinical Indication: Loratadine is indicated for the relief of symptoms and signs of chronic urticaria sand other allergic dermatologic disorders. It is also used in the
relief of symptoms associated with allergic rhinitis such as sneezing, nasal discharge and itching, and ocular itching and burning.
Pregnancy Category: Category B: Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or
animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimester).
C. Name: Fexofenadine HClStructure:
IUPAC: 4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl] butyl]-α,α dimethylbenzeneacetic acid hydrochlorideTrade Name Manufacturer Selling Price
Fenafex Eadriex Film-coated tablet 120 mg: 30's (P660.00/ box)
Fexet Getz Pharma Film-coated tablet 120 mg: 10's (P242.00/ box)
Neofex GXI Film-coated tablet 120 mg: 50's (P23.00/tab)
Telfast Sanofi-aventis Film-coated tablet 120 mg: 50's (P2311.14/ box)Film-coated tablet 180 mg: 50's (P2590.68/box)
Rhinogan Beximco/Euro Generics Film-coated tablet 120 mg: 30's (P630.00/ box)
Dosage Form and Strength: film-coated tablet 120 mg and 180mg
Clinical Indication:Fexofenadine HCl is indicated for the symptomatic relief of allergic conditions including seasonal allergic rhinitis and chronic urticaria.
Pregnancy Category:Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) an there are no
controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
D. Name: Diphenhydramine HClStructure:
IUPAC name: 2-benzhydryloxy-N,N-dimethylethanamine;hydrochloride
Trade name Manufacturer Selling priceBenadryl AH Johnson & Johnson Benadryl AH cap 25
mg100's (P1663.00/pack)Source: MIMS Philippines
Benadryl AH cap 50 mg
100's (P2810.50/pack)Source: MIMS Philippines
Benadryl AH syrup 12.5 mg/5 mL
60 mL x 1's (P109.25/bottle)Source: MIMS Philippines
120 mL x 1’s(P174.50/bottle)
Source: MIMS Philippines
Soniphen United LabSoniphen soft-gelatin
cap 25 mg
100's (P1037.74/pack)
Source: MIMS Philippines
Soniphen syrup12.5 mg/5 mL
60 mL x 1's (P59.44/bottle)Source: MIMS Philippines
Amherst Lab Soniphen cap 50 mg30's
(P339.62/box)Source: MIMS Philippines
Soniphen inj 50 mg/mL
1 mL x 10's (P1038.20/ampoule)Source: MIMS Philippines
DramelinWescrib
Dramelin cap 50 mg 100’s(P263.00/pack)
Source: MIMS PhilippinesDramelin syrup
12.5mg/5mL60 mL x 1's (P70.00/bottle)
Source: MIMS Philippines
RiteMed Diphenhydramine HCl
RiteMedRiteMed
Diphenhydramine HCl cap 50 mg
100’s(P700.00/pack)
Source: Mercury Drug Store
Bexil Zhejiang RuixinBexil inj
50 mg/mL
1 mL x 10 x 1's (P130.00/ampoule)
Source: MIMS Philippines
Dosage Form and Strength: Capsule 25 mg Capsule 50 mg Syrup 12.5 mg/5 mL
o 60 mLo 120 mL
Injection 50 mg/mL
Clinical Indication:Antihistaminic: For perennial and seasonal (hay fever) allergic rhinitis; vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and
foods; amelioration of allergic reactions to blood or plasma, dermatographism; as therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have been controlled.
Motion Sickness: For active and prophylactic treatment of motion sickness.Antiparkinsonism: For parkinsonism (including drug-induced extrapyramidal reactions) in the elderly unable to tolerate more potent agents; mild
cases of parkinsonism (including drug-induced) in other age groups; in other cases of parkinsonism (including drug-induced) in combination with centrally-acting anticholinergic agents.
Pregnancy Category: Category B: Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or
animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimester).
E. Name: LevocetirizineStructure:
IUPAC name: 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
Trade Name Manufacturer Selling PriceLevocet Natrapharm Tablet 5 mg:
(P16.50/tab)Zykast Ajanta Tablet 5 mg:
(P27.16/tab)Xyzal UCB Pharma, Inc. Tablet 5mg:
(P22.40/tab) Oral solution 2.5/5mL: (P181.00/bottle)
L-ZET Twilight Litaka Tablet 5 mg: (P16.00/tab)
Sensitrin XL Lab/ Ambica Tablet 5 mg: (P18.00/tab)
Dosage Form and Strength: oral solution 2.5 mg/5mL tablet 5 mg
Clinical Indication:Levocetirizine is indicated for the symptomatic treatment of seasonal and perennial allergic rhinitis including persistent allergic rhinitis and
chronic idiopathic urticarial.
Pregnancy Category:
Category B: Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimester).
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