Acknowledgements: This work was funded in part by grant BAA-AFOSR-2013-0001 (to D.M., D.P. and K.M.). Data

collection was conducted at the Athinoula A. Martinos Imaging Center at the McGovern Institute at MIT.

DDDAS 2017 Conference, MITAugust 2017

Horizontal eye position

Vertical eye position

Pupil diameter

Brain 10 Hz alpha oscillations

Pupil diameter

Partial eye closure

Conditional random fields

Leve

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Res

ista

nce

(s

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oga

te o

f fa

tigu

e)

Time blocks

1 2 3 4 5 6

1

2

3

4

5

6

7

0

Predict mental fatigue