TO UNDERSTAND THE PERCEPTION AND ATTITUDE OF PHYSICIAN,RETAILERS AND PATIENTS TOWARDS THE USE OF METERED SPRAY SYSTEM FOR SKIN DISEASES OVER CONVENTIONAL MEDICATION

SSUBMITTED BY AMIT KHANNIPER MOHALI

FLOW OF PRESENTATION

COMPANY PROFILE

LITERATURE REVIEW

RESARCH METHODOLOGY

DATA ANALYSIS

KEY FINDINGS

RECOMMENDATIONS

COMPANY’S PROFILE

INJECTABLES

CONSUMER HEALTH

CARE

PRESCRIPTION

INNOVATION AT THE CORE,DRIVING PATIENT- FOCUSED DRUG DELIVERY SOLUTION

PRESCRIPTION DIVISON

Allergic rhinitis

Asthma and COPD

Pain

Skin diseases

Central nervous system

Cont…

Aptar pharma business dedicated to the evolving needs of biotechnology, healthcare and pharmaceutical companies with innovative drug delivery solutions.With a strong focus on leveraging innovation to provide patient-focused solutions, allocate 5% of annual revenue to research and development.Having manufacturing sites in Argentina, China, France, Germany, India, Switzerland and the U.S.A. serving the pharmaceutical industry market worldwide.

Cont…Global leaderAptar is worldwide leader in metering valves used in pMDIs in treatment of Asthma and COPD

High volume global manufacturingMore than 1 billion proprietary drug delivery devices manufactured each year

Multi-talented workforce 3,050 employees (research scientists, technical experts, sales force personnel and manufacturing and services staff)

R&D investment in the future• 5% of annual revenue in Research & Development

activities

CLIENTS OF APTAR PHARMA

PROJECT PLAN

Literature review and introduction to projects and objectives

Questionnaire design and approval

Pilot testing and field study amongst dermatologists

Data analysis and

interpretation of key findings

Report preparation submission

and discussion

SKIN DISEASES AN OVERVIEW…

Fungal infection fungal infection

mainly caused by fungus

tinea pedis sypmtoms peeling,

redness, itching, burning, and

sometimes blisters and sores.

SCABIESSCABIES

Scabies is a skin infection caused by a tiny microscopic

bug known as the human itch

mite. This mite is usually passed

from skin to skin. It can also be transmitted

through infested clothing or bedding.

SKIN ALLERGY

SKIN ALLERGYIrritated skin can be caused by a variety of factors. These immune

system disorders, medications and

infections. When an allergen is responsible

for triggering an immune system

response, then it is an allergic skin condition.

Skin allergy

Angioedema

Urticaria

Contact dermatitis

Atopic dermatitis

Cont…

Atopic dermatitis Urticaria

Acne vulgaris

Acne vulgaris is a skin problem that starts when oil and dead skin cells clog up your pores. Some people call it blackheads, blemishes, whiteheads, pimples, or zits. When you have just a few red spots, or pimples, you have a mild form of acne. Acne

RESEARCH METHODOLOGY

TO UNDERSTAND THE PERCEPTION AND ATTITUDE OF PHYSICIAN,RETAILERS AND PATIENTS TOWARDS THE USE OF METERED SPRAY SYSTEM FOR NEUROLOGICAL DISORDERS OVER CONVENTIONAL

MEDICATION

SECONDRY OBJECTIVES

To find out which feature of metered spray systems physicians and retailers like the most

To find out the prescribing behavior of the physicians for metered spray systems

To gain insight on the attributes which general physicians consider while selecting the medicine and

dosage form for treatment of skin disease

To get insight about the price consciousness of the patients from the physicians and retailers

To find out the discomforts that patients usually faced during the treatment by existing medication

skin disease

RESEARCH PLANSR.NO PARAMETER DATA1 research type quantitative2 type of data primary data3 type of questionnaire structured4 mode of data collection personal interview5 sample selection specialty wise6 target respondents Dermatologists retailers,

patients7 sample size 2108 sample unit 70 dermatologists,70

retailers,70 patients9 sampling technique Convenient sampling10 tool of data collection Questionnaire containing

open ended and closed ended questions

11 area covered Haryana(ynr,amb,chd,kkr,Kar,)

`DATA ANALYSIS

DERMATOLOGISTS RESPONSE

MOST COMMON SKIN PROBLEMS OBSERVED WITH PATIENTS?

ACNE ALLERGY FUNGAL INFECTION

OTHERS SCABIES0

10203040506070

NO. OF PATIENTS

NO

.OF

PATI

ENT

IN %

Majority of dermatologists revealed that Allergy and fungal infection are the most prevalent skin disease in patients

HOW MANY PATIENTS YOU GET PER DAY OF SKIN DISEASES?

(0-10) (10-20) (20-30) > 300%

5%

10%

15%

20%

25%

30%

35%

40%

As per the above responses obtained from physicians vindicating that there is huge market potential for the drugs used in the treatment of skin problems

due to huge prevalence of skin diseases

DO PATIENT FEEL ANY DISCOMFORT WHILE ON MEDICATION?

NO; 34%

YES; 66%

Majority of patients feel discomfort with existing medications for skin diseases as revealed by the physicians

40%

16%

26%

13%5%

always oftensometimes rarelynever

Dermatologists Retailers

yes57%

no43%

Patients

IF YES, WHAT KIND OF DISCOMFORT PATIENT USUALLY FACES?

37%

50%

13%

drug administration and application problemsadverse drug reactiondosage form frequencyany other

59%

39%

2%

Retailers

physician

Major Adverse drug reactionDrowsinessGiddiness

Abdominal discomfortvomiting

59%23%

10%

9%

patients

Administration and application problems

Size of tabletGreasiness

Assistance is required

WHICH DOSAGE FORM YOU PREFER USUALLY WHEN PRICE IS NOT A CONSTRAINT?

16%

69%

3%

2% 10%

SOLID DOSAGE FORM SEMI-SOLID DOSAGE FORMLIQUID DOSAGE FORMINJECTABLESSPRAY SOLUTIONS

When price is not a constraint for physician most of the physicians agreed to prescribe semi-solid dosage form to patients like ointments, creams for local

application.

DO YOU THINK SPRAY SYSTEM IS THE BETTER AND SAFER WAY OF MEDICATION?

97%

3%

YESNO

Almost every physician and a considerable number of retailers are in the favor of statement that spray systems are better and safer way of medication as

compared to conventional medication

16%

24%

56%

4%

strongly disagree disagreeneutral agreestrongly agree

Dermatologist Retailers

WHICH FEATURES OF SPRAY SYSTEM YOU LIKE MOSTLY?

6%

37%

27%

28%2%

DOSE UNIFORMITYQUICK ONSET OF ACTIONSAFETYEFFECTIVENESSOTHERS

Quick onset of action, safety and effectiveness are the mostly liked features of spray system by the physicians

ARE YOU CURRENTLY PRESCRIBING ANY SPRAY SYSTEM?

YES15%

NO85%

Spray system prescription

Only very few number of the physicians insists on prescribing spray system to patients

DO YOU THINK PATIENTS WILL PAY EXTRA FOR SPRAY SYSTEM?

YES30%

NO70%

As per the responses obtained from doctors and retailers only 1\3 of the patients can pay extra for spray system, inferred the price conscious nature

of patients

YES23%

NO77%

Dermatologists Retailers

IF YES, THEN HOW MUCH EXTRA PATIENTS CAN PAY FOR SPRAY SYSTEM?

2-5% 5-10% 10-15% >150

10

20

30

40

50

60

As per the physician the patient can pay a small amount of extra price for spray system, not more then 10%

WHICH FEATURES OF SPRAY SYSTEM YOU THINK SHOULD BE IMPROVED

efficacy price packaging volume of container

other05

10152025303540

% o

f phy

sici

ans

A large group of physician want improvement in efficacy and affordability of spray system to patients

RETAILERS RESPONSES

DATA ANALYSIS

MOST POPULAR BRANDS FOR SKIN DISEASES

WHY THESE BRANDS ARE SO POPULAR?

effectiveness safety affordability non availability f other option

any other

94.00%

14.00%

58.80%

3.00%

As per the retailers these brands are popular due to there effectiveness and affordability to patients

DO PATIENT BUY PRESCRIBED MEDICINES ONLY?

ALWAYS OFTEN SOMETIMES RARELY NEVER0

10

20

30

40

50

60

70

80

90

As stated by most of the retailers that patients are more conscious for purchasing prescribed medicines only

IF NOT THEN,WHICH FACTOR MOSTLY INFLUENCE THE PATIENT TO SWITCH OVER OTHER BRANDS?

effective

nesssafet

ypric

e

dosage form

non availb

ility o

f medicin

es

any other

0

10

20

30

40

50

60

Half of the retailers agreed that price is major concern for patients to switch over other brands

WOULD YOU ENCOURGE THE PATIENT TO BUY SPRAY SYSTEM?

YES30%

NO70%

Majority of retailers are agree to encourage the patients to buy the spray systems

ARE YOU AWARE ABOUT SPRAY SYSTEM FOR SKIN PROBLEMS

YES89%

NO11%

A very few number of retailers are aware about spray solution for skin disease

PATIENT’S REPONSES

DATA ANALYSIS

WHICH SKIN PROBLEM DO YOU HAVE?

fungal in-fection

skin allergy scabies acne other0

5

10

15

20

25

30

35

% o

f pati

ents

Skin Allergy and fungal infection are the most prevalent skin disease among patients

ARE YOU AWARE OF AVAILABILITY OF SPRAY SYSTEM FOR SKIN PROBLEMS?

yes12%

no88%

Awareness among patients

it is glaringly inferred from above graph that is patients are not aware about spray system for skin problems

WOULD YOU PREFER TO USE SPRAY SYSTEM OVER CONVENTIONAL MEDICATION?

YES87%

NO13%

Most of the patients wanted to use spray system over conventional medication

WOULD YOU WILLING TO PAY EXTRA FOR SPRAY SYSTEM?

YES24%

NO76%

76% of the patients are reluctant to pay extra for spray system

KEY FINDINGS

A large group of people are suffering from skin disease

Fungal infection and skin allergy are the most prevalent skin

disease among patients

Most of the patients feel discomfort with existing medications

Patients

PREVALENCE

Spray system are effective and safe

way of drug administration or

applicationThere is lack of

awareness about availability of spray

system for skin diseases

Spray systems are having quick onset of

action and effectiveness

OPINION ABOUT SPRAY SYSTEM

Physicians mainly rely on semi-solid dosage form like cream and ointment for direct

application over skinPhysicians are not able to prescribe spray system to

patients due to there price conscious nature

PHYSICIANS PERCEPTION

RECOMMENDATIONS• Awareness program - campaign should be planned for spreading

awareness because large group of retailers, patients and even physicians are not aware about the spray system availability at market place

• Affordability- physicians are reluctant to prescribe spray systems due to there expensive nature over conventional medications so the price of spray system should be with in the reach of patients.

• Design of container - the product should be available in small volume packages that would be more affordable as well as convenient for patients to purchase

• Labeling- Proper instruction regarding its operation and administration should be clearly mentioned over the container

LEARNINGS FROM THE TRAINING

SECONDARY RESEARCH:- LITERATURE REVIEW OF GASTROINTESTINAL SYSTEM IN HUMANS- ASSOCIATING LITERATURE WITH THE OBJECTIVES OF THE STUDY QUESTIONNAIRE DESIGN:- FLOW OF THE QUESTIONNAIRE - FRAMING QUESTIONS BASED ON OBJECTIVES & CURRENT DATA- CONSIDERING FACTORS WHICH AFFECT THE STUDY PRIMARY RESEARCH:- PILOT STUDY OF THE QUESTIONNAIRE & CORRECTIONS BASED ON THE SAME- APPROACH TOWARDS THE DOCTORS TO EXTRACT RELEVANT INFORMATION DATA ANALYSIS & INTERPRETATION:- SUMMARIZING RESEARCH FINDINGS & INTERPRETATION OF THESE FINDINGS- IMPLICATIONS OF THESE FINDINGS ON FUTURE ACTIVITIES - DISCUSSION OF THE PROJECT WITH SENIOR AUTHORITIES.