1998 amino acids, peptides

amino acids, peptidesU 0400

21 - 182An Efficient Stereoselective Synthesis of Sphingosine. — The key stepin the large scale synthesis of the sphingosine (VI) is an addition–fragmentationreaction of tosyl hydrazones of the isopropylidene-D-xylose (III) with Grignardreagents such as (IV) for the chain extension with concomitant trans-selectiveC=C bond formation. — (KUMAR, P.; SCHMIDT, R. R.; Synthesis (1998) 1,33-35; Fak. Chem., Univ. Konstanz, D-78434 Konstanz, Germany; EN)

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